References
- Elder , R. C. , Florian , L. R. , Kennedy , E. R. and Macomber , R. S. 1973 . J. Org. Chem. , 38 : 4177
- Macomber , R. S. and Kennedy , E. R. 1976 . J. Org. Chem. , 41 : 3191
- Macomber , R. S. 1977 . J. Am. Chem. Soc. , 99 : 3072
- Macomber , R. S. , Krudy , G. A. , Seff , K. and Diaz-Miron , L. E. R. 1983 . J. Org. Chem. , 48 : 1425
- Macomber , R. S. , Constantinides , I. and Garrett , G. 1985 . J. Orq. Chem. , 50 : 4711
- The rate constant was measured by 1H nmr. The isomerization could also be carried out in 3/2 (v/v) CD3CN/CD3OD at 80°, to give 3b (deuteriated at C4) with kobs = 7.5 × 10−3 h−1 and kcat = 3.0 × 10−2 h−1M−1
- Compound 2b is also inert to 2 M HCl for 11 d at 90°.2