References
- Organon International B. V., P. O. Box 20, 5340 BH Oss, The Netherlands.
- Ottenheijm , H. C. J. , Van den Broek , L. A. G. M. , Ballesta , J. P. G. and Zylicz , Z. 1986 . Progress in Medicinal Chemistry , Edited by: Ellis , G. P. and West , G. B. Vol. 23 , 219 – 268 . Amsterdam : Elsevier .
- Van den Broek , L. A. G. M. , Liskamp , R. M. J. , Colstee , J. H. , Lelieveld , P. , Remacha , M , Vázquez , D. , Ballesta , J. P. G. and Ottenheijm , H. C. J. 1987 . J. Med. Chem. , 30 : 325
- Ottenheijm , H. C. J. , Liskamp , R. M. J. , Van Nispen , S. P. J. M. , Boots , H. A. and Tijhuis , M. W. 1981 . J. Org. Chem. , 46 : 3273
- Van den Broek , L. A. G. M. , Lázaro , E. , Fennis , P. J. , Missler , F. A. N. , Lelieveld , P. , Ballesta , J. P. G. and Ottenheijm , H. C. J. Manuscript accepted for publication in J. Med. Chem.
- Bernady , K. F. , Floyd , M. B. , Poletto , J. F. and Weiss , M. J. 1979 . J. Org. Chem. , 44 : 1438
- Chasar , D. W. and Pratt , T. M. 1976 . Synthesis , : 262 Originally, the reduction reaction is described to be carried out in benzene; we observed, however, that CH2Cl2 is a more suitable solvent.
- Castrillón , J. P. A. and Szmant , H. H. 1965 . J. Org. Chem. , 30 : 1338 However, under these reaction conditions 3b, 3d and 3e decomposed. Another procedure studied involves the use of PPh3 in refluxing CCl4 for 2–18 hr:
- Russel , G. A. and Ochrymowycz , L. A. 1970 . J. Org. Chem. , 35 : 2106
- Corey , E. J. , Niwa , H. and Knolle , J. 1978 . J. Am. Chem. Soc. , 100 : 1942
- Von Arx , E. , Faupel , M. and Brugger , M. 1976 . J. Chromatogr. , 120 : 224