A Facile Method for the Preparation of Functionalized 2-Halo-1-olefins

References

• Lansbury , P. T. 1972 . Acc. Chem. Res. , 5 : 311
   Google Scholar
• Thornberry , N. A. , Bull , H. G. , Taub , D. , Greenlee , W. J. , Patchett , A. A. and Cordes , E. H. 1987 . J. Am. Chem. Soc. , 109 : 7543
   Web of Science ®Google Scholar
• Cousseau Gouin , J. 1977 . J. Chem. Soc. Perkin Trans. , 1 : 1797
   Google Scholar
• Cousseau , J. 1980 . Synthesis , : 805
   Google Scholar
• Engman , L. 1987 . Tetrahedron Lett. , 28 : 1463
   Web of Science ®Google Scholar
• Raucher , S. 1977 . Tetrahedron Lett. , : 3909
   Google Scholar
• Lespieau , R. and Bourguel , M. 1941 . Org. Syn. Coll. , 1 : 180
   Google Scholar
• Zhu , L. , Wehmeyer , R. M. and Rieke , R. D. 1991 . J. Org. Chem. , 56 : 1445
   Web of Science ®Google Scholar
• Zhu , L. and Rieke , R. D. 1991 . Tetrahedron Lett. , 32 : 2865
   Google Scholar
• Knochel , P. , Yeh , M. C. P. , Berk , S. C. and Talbert , J. 1988 . J. Org. Chem. , 53 : 2392
   Web of Science ®Google Scholar
• In this experiment, we modified the method (ref. 5) for the preparation of highly reactive zinc by using 5–10 mol% of naphthalene based on lithium as an electron carrier. After the mixture of lithium and naphthalene in THF was stirred for about 5 min, ZnCl2/THF solution was transferred by cannula to it at a rate such that the greenish color persisted until all the lithium was consumed. The activity of the zinc was the same as the method reported earlier.5 The advantages of this method are three fold: using a catalytic amount of naphthalene, shortening the reduction times and ease of product purification
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