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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 24, 1994 - Issue 11
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Original Articles

An Efficient Degradation of Tazobactam, a Beta-Lactamase Inhibitor, to Metabolite M-1

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Pages 1597-1601 | Received 01 Nov 1993, Published online: 23 Sep 2006

References

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  • Bush , K. , Macalintal , C. , Rasmussen , B. A. , Lee , V. J. and Yang , Y. 1993 . Antimicrob. Agents Chem. , 37 : 851
  • Haginaka , J. , Wakai , J. , Yasuda , H. , Uno , T. and Nakagawa , T. 1985 . Chem. Pharm Bull. , 33 : 2035 For alkaline degradation of sulbactam
  • Haginaka , J. , Wakai , J. , Yasuda , H. , Uno , T. and Nakagawa , T. 1985 . Chem. Pharm. Bull. , 33 : 4923 For discussion of pyrazole-catalyzed degradation of sulbactam
  • Howarth , T. T. , Brown , A. G. and King , T. J. 1976 . J. Chem. Soc., Chem. Commun. , : 266 For degradation studies of clavulanic acid
  • Marunaka , T. , Matsushima , E. , Minami , Y. , Yoshida , K.-I. and Azuma , R. 1988 . Chem. Pharm. Bull. , 36 : 4478
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  • Twice recrystallized from water , HPLC . 95.2% (area), 95.0% (weight)

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