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Synthetic Communications
An International Journal for Rapid Communication of Synthetic Organic Chemistry
Volume 26, 1996 - Issue 14
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Original Articles

Alkylation of Tetrazoles Using Mitsunobu Conditions

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Pages 2687-2694 | Received 02 Feb 1996, Published online: 21 Aug 2006

References

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  • Robert-Piessard , S. , Leblois , D. , Kumar , P. , Robert , J. M. , Le Baut , G. , Sparfel , L. , Robert , B. , Khettab , E. , Sanchez , R. Y. , Petit , J. Y. and Welin , L. 1990 . Eur. J. Med. Chem. , 25 : 737
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  • Finnegan , W. G. , Henry , R. A. and Lieber , E. 1953 . J. Org. Chem. , 18 : 779 The tetrazole 1 can be prepared as previously reported. See
  • Garbrecht , W. L. and Herbst , R. M. 1953 . J. Org. Chem. , 18 : 1269 An improvement of one step has been reported. See
  • The J1,3 values for the cyclohexyl methine proton on the carbon bearing tetrazole (δ 5.42) are consistent with a syn relationship to the adjacent methine proton
  • Tsunoda , T. , Yamamiya , Y. , Kawamura , Y. and Itô , S. 1995 . Tetrahedron Lett. , 36 : 2529 For a report on a new combination of reagents which results in higher yields of inverted esters from sterically hindered alcohols. See
  • Herbst , R. M. and Wilson , K. R. 1957 . J. Org. Chem. , 22 : 1142
  • Garbrecht , W. L. and Herbst , R. M. 1953 . J. Org. Chem. , 18 : 1003

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