Control options for Neospora caninum infections in cattle — current state of knowledge

References

• Anderson , ML , Palmer , CW , Thurmond , MC , Picanso , JP , Blanchard , PC , Breitmeyer , RE , Layton , AW , McAllister , M , Daft , B , Kinde , H , Read , DH , Dubey , JP , Conrad , PA and Barr , BC . 1995 . Evaluation of abortions in cattle attributable to neosporosis in selected dairy herds in California . Journal of the American Veterinary Medical Association , 207 : 1206 – 1210 .
   PubMed Web of Science ®Google Scholar
• Andrianarivo , AG , Choromanski , L , McDonough , SP , Packham , AE and Conrad , PA . 1999 . Immunogenicity of a killed whole Neospora caninum tachyzoite preparation formulated with different adjuvants . International Journal for Parasitology , 29 : 1613 – 1625 .
   PubMedGoogle Scholar
• Andrianarivo , AG , Rowe , JD , Barr , BC , Anderson , ML , Packham , AE , Sverlow , KW , Choromanski , L , Loui , C , Grace , A and Conrad , PA . 2000 . A POLYGEN-adjuvanted killed Neospora caninum tachyzoite preparation failed to prevent foetal infection in pregnant cattle following i.v./i.m. experimental tachyzoite challenge . International Journal for Parasitology , 30 : 985 – 990 .
   PubMedGoogle Scholar
• Antony , A and Williamson , NB . 2001 . Recent advances in understanding the epidemiology of Neospora caninum in cattle . New Zealand Veterinary Journal , 49 : 42 – 47 .
   PubMed Web of Science ®Google Scholar
• Atkinson , R , Harper , PAW , Ryce , C , Morrison , DA and Ellis , JT . 1999 . Comparison of the biological characteristics of two isolates of Neospora caninum . Parasitology , 118 : 363 – 370 .
   PubMed Web of Science ®Google Scholar
• Atkinson , R , Harper , PA , Reichel , MP and Ellis , JT . 2000 . Progress in the serodiagnosis of Neospora caninum infections of cattle . Parasitology Today , 16 : 110 – 114 .
   PubMedGoogle Scholar
• Baillargeon , P , Fecteau , G , Paré , J , Lamothe , P and Sauve , R . 2001 . Evaluation of the embryo transfer procedure proposed by the International Embryo Transfer Society as a method of controlling vertical transmission of Neospora caninum in cattle . Journal of the American Veterinary Medical Association , 218 : 1803 – 1806 .
   PubMedGoogle Scholar
• Barber , JS and Trees , AJ . 1996 . Clinical aspects of 27 cases of neosporosis in dogs . Veterinary Record , 139 : 439 – 443 .
   PubMed Web of Science ®Google Scholar
• Barber , JS , Trees , AJ and Johnson , AM . 1998 . Naturally occurring vertical transmission of Neospora caninum in dogs . Proceedings of the 10th International Congress of Protozoology , 28 : 57 – 64 .
   Google Scholar
• Barling , KS , McNeill , JW , Thompson , JA , Paschal , JC , McCollum , FT 3rd , Craig , TM and Adams , LG . 2000a . Association of serologic status for Neospora caninum with postweaning weight gain and carcass measurements in beef calves . Journal of the American Veterinary Medical Association , 217 : 1356 – 1360 .
   PubMedGoogle Scholar
• Barling , KS , Sherman , M , Peterson , MJ , Thompson , JA , McNeill , JW , Craig , TM and Adams , LG . 2000b . Spatial associations among density of cattle, abundance of wild canids, and seroprevalence to Neospora caninum in a population of beef calves . Journal of the American Veterinary Medical Association , 217 : 1361 – 1365 .
   PubMedGoogle Scholar
• Barr , BC , Anderson , ML , Woods , LW , Dubey , JP and Conrad , PA . 1992 . Neospora-like protozoal infections associated with abortion in goats . Journal of Veterinary Diagnostic Investigation , 4 : 365 – 367 .
   PubMedGoogle Scholar
• Baszler , TV , McElwain , TF and Mathison , BA . 2000 . Immunization of BALB/c mice with killed Neospora caninum tachyzoite antigen induces a type-2 immune response and exacerbates encephalitis and neurological disease . Clinical and Diagnostic Laboratory Immunology , 7 : 893 – 898 .
   PubMedGoogle Scholar
• Bergeron , N , Fecteau , G , Paré , J , Martineau , R and Villeneuve , A . 2000 . Vertical and horizontal transmission of Neospora caninum in dairy herds in Quebec . Canadian Veterinary Journal , 41 : 464 – 467 .
   PubMed Web of Science ®Google Scholar
• Bergeron , N , Girard , C , Paré , J , Fecteau , G , Robinson , J and Baillargeon , P . 2001 . Rare detection of Neospora caninum in placentas from seropositive dams giving birth to full-term calves . Journal of Veterinary Diagnostic Investigation , 13 : 173 – 175 .
   PubMedGoogle Scholar
• Bjerkås , I , Mohn , SF and Presthus , J . 1984 . Unidentified cyst-forming sporozoon causing encephalomyelitis and myositis in dogs . Zeitschrift für Parasitenkunde , 70 : 271 – 274 .
   PubMed Web of Science ®Google Scholar
• Björkman , C , Johansson , O , Stenlund , S , Holmdahl , OJM and Uggla , A . 1996 . Neospora species infection in a herd of dairy cattle . Journal of the American Veterinary Medical Association , 208 : 1441 – 1441 .
   PubMedGoogle Scholar
• Björkman , C , Alenius , S , Manuelsson , U and Uggla , A . 2000 . Neospora caninum and bovine virus diarrhoea virus infections in Swedish dairy cows in relation to abortion . The Veterinary Journal , 159 : 201 – 206 .
   PubMed Web of Science ®Google Scholar
• Boulton , JG , Gill , PA , Cook , RW , Fraser , GC , Harper , PAW and Dubey , JP . 1995 . Bovine Neospora abortion in north-eastern New South Wales . Australian Veterinary Journal , 72 : 119 – 120 .
   PubMedGoogle Scholar
• Brownlie , J , Clarke , MC , Hooper , LB and Bell , GD . 1995 . Protection of the bovine fetus from bovine viral diarrhoea virus by means of a new inactivated vaccine . Veterinary Record , 137 : 58 – 62 .
   PubMed Web of Science ®Google Scholar
• Choromanski , L and Block , W . 2000 . Humoral immune responses and safety of experimental formulations of inactivated Neospora vaccines . Parasitology Research , 86 : 851 – 853 .
   PubMedGoogle Scholar
• Conrad , PA , Sverlow , K , Anderson , M , Rowe , J , BonDurant , R , Tuter , G , Breitmeyer , R , Plamer , C , Thurmond , M , Ardans , A , Dubey , JP , Duhamel , G and Barr , B . 1993 . Detection of serum antibody response in cattle with natural or experimental Neospora infections . Journal of Veterinary Diagnostic Investigation , 5 : 572 – 578 .
   PubMed Web of Science ®Google Scholar
• Cox , BT , Reichel , MP and Griffiths , LM . 1998 . Serology of a Neospora abortion outbreak on a dairy farm in New Zealand: a case study . New Zealand Veterinary Journal , 46 : 28 – 31 .
   PubMed Web of Science ®Google Scholar
• Davison , HC , Otter , A and Trees , AJ . 1999 . Estimation of vertical and horizontal transmission parameters of Neospora caninum infections in dairy cattle . International Journal for Parasitology , 29 : 1683 – 1689 .
   PubMed Web of Science ®Google Scholar
• Davison , HC , Guy , CS , McGarry , JW , Guy , F , Williams , DJ , Kelly , DF and Trees , AJ . 2001 . Experimental studies on the transmission of Neospora caninum between cattle . Research in Veterinary Science , 70 : 163 – 168 .
   PubMed Web of Science ®Google Scholar
• Dijkstra , T , Eysker , M , Schares , G , Conraths , FJ , Wouda , W and Barkema , HW . 2001 . Dogs shed Neospora caninum oocysts after ingestion of naturally infected bovine placenta but not after ingestion of colostrum spiked with Neospora caninum tachyzoites . International Journal for Parasitology , 31 : 747 – 752 .
   PubMed Web of Science ®Google Scholar
• Dijkstra , T , Barkema , HW , Hesselink , JW and Wouda , W . 2002a . Point source exposure of cattle to Neospora caninum consistent with periods of common housing and feeding and related to the introduction of a dog . Veterinary Parasitology , 105 : 89 – 98 .
   PubMedGoogle Scholar
• Dijkstra , T , Barkema , HW , Eysker , M , Hesselink , JW and Wouda , W . 2002b . Natural transmission routes of Neospora caninum between farm dogs and cattle . Veterinary Parasitology , 105 : 99 – 104 .
   PubMed Web of Science ®Google Scholar
• Dubey , JP . 1992 . Neosporosis — a newly recognized protozoal infection . Comparative Pathology Bulletin , 24 : 4 – 6 .
   Google Scholar
• Dubey , JP . 1999a . Recent advances in Neospora and neosporosis . Veterinary Parasitology , 84 : 349 – 367 .
   PubMed Web of Science ®Google Scholar
• Dubey , JP . 1999b . Neosporosis in cattle: biology and economic impact . Journal of the American Veterinary Medical Association , 214 : 1160 – 1163 .
   PubMedGoogle Scholar
• Dubey , JP and Lindsay , DS . 1996 . Areview of Neospora caninum and neosporosis . Veterinary Parasitology , 67 : 1 – 59 .
   PubMed Web of Science ®Google Scholar
• Dubey , JP and Porterfield , ML . 1990 . Neospora caninum (Apicomplexa) in an aborted equine fetus . Journal of Parasitology , 76 : 732 – 734 .
   PubMedGoogle Scholar
• Dubey , JP , Christie , E and Pappas , PW . 1977 . Characterization of Toxoplasma gondii from the feces of naturally infected cats . The Journal of Infectious Diseases , 136 : 432 – 435 .
   PubMed Web of Science ®Google Scholar
• Dubey , JP , Hartley , WJ and Lindsay , DS . 1990a . Congenital Neospora caninum infection in a calf with spinal cord anomaly . Journal of the American Veterinary Medical Association , 197 : 1043 – 1044 .
   PubMedGoogle Scholar
• Dubey , JP , Hartley , WJ , Lindsay , DS and Topper , MJ . 1990b . Fatal congenital Neospora caninum infection in a lamb . Journal of Parasitology , 76 : 127 – 130 .
   PubMed Web of Science ®Google Scholar
• Dubey , JP , Metzger , FL Jr , Hattel , AL , Lindsay , DS and Fritz , DL . 1995 . Canine cutaneous neosporosis: clinical improvement with clindamycin . Veterinary Dermatology , 6 : 37 – 43 .
   PubMedGoogle Scholar
• Dubey , JP , Jenkins , MC , Adams , DS , McAllister , MM , AndersonSprecher , R , Baszler , TV , Kwok , OCH , Lally , NC , Björkman , C and Uggla , A . 1997 . Antibody responses of cows during an outbreak of neosporosis evaluated by indirect fluorescent antibody test and different enzyme-linked immunosorbent assays . Journal of Parasitology , 83 : 1063 – 1069 .
   PubMed Web of Science ®Google Scholar
• Dyer , RM , Jenkins , MC , Kwok , OC , Douglas , LW and Dubey , JP . 2000 . Serologic survey of Neospora caninum infection in a closed dairy cattle herd in Maryland: risk of serologic reactivity by production groups . Veterinary Parasitology , 90 : 171 – 181 .
   PubMed Web of Science ®Google Scholar
• Ellis , JT . 1997 . “ Neospora caninum: prospects for diagnosis and control using molecular methods ” . In Proceedings of the VII International Coccidiosis Conference and EU COST820 Workshop , Edited by: Shirley , MW , Tomley , FM and Freeman , BM . 80 – 81 . Oxford : Oxford Institute for Animal Health .
   Google Scholar
• French , NP , Clancy , D , Davison , HC and Trees , AJ . 1999 . Mathematical models of Neospora caninum infection in dairy cattle: transmission and options for control . International Journal for Parasitology , 29 : 1691 – 1704 .
   PubMed Web of Science ®Google Scholar
• Gottstein , B , Kritzner , S , Cannas , A , Sager , H and Greif , G . 2001 . Toltrazuril and Ponazuril for treatment of experimental murine and bovine neosporosis . Proceedings of the 18th International Conference of the World Association for the Advancement of Veterinary Parasitology , B9
   Google Scholar
• Guy , CS , Williams , DJL , Smith , R , McKay , J , Guy , F , McGarry , JW and Trees , AJ . 2001 . Protective immunity in bovine neosporosis . Proceedings of the 18th International Conference of the World Association for the Advancement of Veterinary Parasitology , B10
   Google Scholar
• Innes , EA , Buxton , D , Maley , S , Wright , S , Marks , J , Esteban , I , Rae , A , Schock , A and Wastling , J . 2000 . Neosporosis. Aspects of epidemiology and host immune response . Annals of the New York Academy of Sciences , 916 : 93 – 101 .
   PubMedGoogle Scholar
• Innes , EA , Lunden , A , Esteban , I , Marks , J , Maley , S , Wright , S , Rae , A , Harkins , D , Vermeulen , A , McKendrick , IJ and Buxton , D . 2001a . A previous infection with Toxoplasma gondii does not protect against a challenge with Neospora caninum in pregnant sheep . Parasite Immunology , 23 : 121 – 132 .
   PubMedGoogle Scholar
• Innes , EA , Wright , SE , Maley , S , Rae , A , Schock , A , Kirvar , E , Bartley , P , Hamilton , C , Carey , IM and Buxton , D . 2001b . Protection against vertical transmission in bovine neosporosis . International Journal for Parasitology , 31 : 1523 – 1534 .
   PubMedGoogle Scholar
• Jenkins , MC , Wouda , W and Dubey , JP . 1997 . Serological response over time to recombinant Neospora caninum antigens in cattle after a neosporosis-induced abortion . Clinical and Diagnostic Laboratory Immunology , 4 : 270 – 274 .
   PubMedGoogle Scholar
• Jensen , AM , Björkman , C , Kjeldsen , AM , Wedderkopp , A , Willadsen , C , Uggla , A and Lind , P . 1999 . Associations of Neospora caninum seropositivity with gestation number and pregnancy outcome in Danish dairy herds . Preventive Veterinary Medicine , 40 : 151 – 163 .
   PubMedGoogle Scholar
• Lally , NC , Jenkins , MC and Dubey , JP . 1996 . Evaluation of two Neospora caninum recombinant antigens for use in an enzyme-linked immunosorbent assay for the diagnosis of bovine neosporosis . Clinical and Diagnostic Laboratory Immunology , 3 : 275 – 279 .
   PubMedGoogle Scholar
• Liddell , S , Jenkins , MC , Collica , CM and Dubey , JP . 1999 . Prevention of vertical transfer of Neospora caninum in BALB/c mice by vaccination . Journal of Parasitology , 85 : 1072 – 1075 .
   PubMedGoogle Scholar
• Lindsay , DS and Dubey , JP . 1989a . Evaluation of anti-coccidial drugs' inhibition of Neospora caninum development in cell cultures . Journal of Parasitology , 75 : 990 – 992 .
   PubMedGoogle Scholar
• Lindsay , DS and Dubey , JP . 1989b . In vitro development of Neospora caninum (Protozoa: Apicomplexa) from dogs . Journal of Parasitology , 75 : 163 – 165 .
   PubMed Web of Science ®Google Scholar
• Lindsay , DS , Rippey , NS , Cole , RA , Parsons , LC , Dubey , JP , Tidwell , RR and Blagburn , BL . 1994 . Examination of the activities of 43 chemotherapeutic agents against Neospora caninum tachyzoites in cultured cells . American Journal of Veterinary Research , 55 : 976 – 981 .
   PubMed Web of Science ®Google Scholar
• Lindsay , DS , Butler , JM , Rippey , NS and Blagburn , BL . 1996 . Demonstration of synergistic effects of sulfonamides and dihydrofolate reductase/thymidylate synthase inhibitors against Neospora caninum tachyzoites in cultured cells, and characterization of mutants resistant to pyrimethamine . American Journal of Veterinary Research , 57 : 68 – 72 .
   PubMedGoogle Scholar
• Lindsay , DS , Butler , JM and Blagburn , BL . 1997 . Efficacy of decoquinate against Neospora caninum tachyzoites in cell cultures . Veterinary Parasitology , 68 : 35 – 40 .
   PubMedGoogle Scholar
• Lindsay , DS , Lenz , SD , Dykstra , CC , Blagburn , BL and Dubey , JP . 1998 . Vaccination of mice with Neospora caninum: Response to oral challenge with Toxoplasma gondii oocysts . Journal of Parasitology , 84 : 311 – 315 .
   PubMedGoogle Scholar
• Lindsay , DS , Dubey , JP and Duncan , RB . 1999a . Confirmation that the dog is a definitive host for Neospora caninum . Veterinary Parasitology , 82 : 327 – 333 .
   PubMed Web of Science ®Google Scholar
• Lindsay , DS , Lenz , SD , Blagburn , BL and Brake , DA . 1999b . Characterization of temperature-sensitive strains of Neospora caninum in mice . Journal of Parasitology , 85 : 64 – 67 .
   PubMedGoogle Scholar
• Mainar-Jaime , RC , Berzal-Herranz , B , Arias , P and Rojo-Vazquez , FA . 2001 . Epidemiological pattern and risk factors associated with bovine viral-diarrhoea virus (BVDV) infection in a non-vaccinated dairy-cattle population from the Asturias region of Spain . Preventive Veterinary Medicine , 52 : 63 – 73 .
   PubMed Web of Science ®Google Scholar
• McAllister , MM , Huffman , EM , Hietala , SK , Conrad , PA , Anderson , ML and Salman , MD . 1996 . Evidence suggesting a point source exposure in an outbreak of bovine abortion due to neosporosis . Journal of Veterinary Diagnostic Investigation , 8 : 355 – 357 .
   PubMed Web of Science ®Google Scholar
• McAllister , MM , Dubey , JP , Lindsay , DS , Jolley , WR , Wills , RA and McGuire , AM . 1998 . Dogs are definitive hosts of Neospora caninum . International Journal for Parasitology , 28 : 1473 – 1478 .
   PubMed Web of Science ®Google Scholar
• McAllister , MM , Björkman , C , Anderson-Sprecher , R and Rogers , DG . 2000 . Evidence of point-source exposure to Neospora caninum and protective immunity in a herd of beef cows . Journal of the American Veterinary Medical Association , 217 : 881 – 887 .
   PubMedGoogle Scholar
• Moen , AR , Wouda , W , Mul , MF , Graat , EAM and van Werven , T . 1998 . Increased risk of abortion following Neospora caninum abortion outbreaks: A retrospective and prospective cohort study in four dairy herds . Theriogenology , 49 : 1301 – 1309 .
   PubMed Web of Science ®Google Scholar
• NishikawaY, , Ikeda H , Fukumoto , S , Xuan , X , Nagasawa , H , Otsuka , H and Mikami , T . 2000 . Immunization of dogs with a canine herpesvirus vector expressing Neospora caninum surface protein, NcSRS2 . International Journal for Parasitology , 30 : 1167 – 1171 .
   PubMedGoogle Scholar
• Nishikawa , Y , Inoue , N , Xuan , X , Nagasawa , H , Igarashi , I , Fujisaki , K , Otsuka , H and Mikami , T . 2001 . Protective efficacy of vaccination by recombinant vaccinia virus against Neospora caninum infection . Vaccine , 19 : 1381 – 1390 .
   PubMedGoogle Scholar
• Paré , J , Thurmond , MC and Hietala , SK . 1994 . Congenital Neospora infection in dairy cattle . Veterinary Record , 134 : 531 – 532 .
   PubMed Web of Science ®Google Scholar
• Paré , J , Thurmond , MC and Hietala , SK . 1996 . Congenital Neospora caninum infection in dairy cattle and associated calfhood mortality . Canadian Journal of Veterinary Research , 60 : 133 – 139 .
   PubMed Web of Science ®Google Scholar
• Paré , J , Fecteau , G , Fortin , M and Marsolais , G . 1998 . Seroepidemiologic study of Neospora caninum in dairy herds . Journal of the American Veterinary Medical Association , 213 : 1595 – 1598 .
   PubMed Web of Science ®Google Scholar
• Pfeiffer , DU , Wichtel , JJ , Reichel , MP , Williamson , NB , Teague , WR and Thornton , RN . 1998 . “ Investigations into the epidemiology of Neospora caninum infection in dairy cattle in New Zealand ” . In Proceedings of the 15th Annual Seminar of the Society of Dairy Cattle Veterinarians of the New Zealand Veterinary Association 279 – 292 .
   Google Scholar
• Pfeiffer , DU , Williamson , NB and Reichel , MP . 2000 . “ Long-term serological monitoring as a tool for epidemiological investigation of Neospora caninum infection in a New Zealand dairy herd ” . In Proceedings of the IX Symposium of the International Society of Veterinary Epidemiology and Economics 524 – 524 .
   Google Scholar
• Raghupathy , R . 1997 . Th-1 type immunity is incompatible with successful pregnancy . Immunology Today , 18 : 478 – 482 .
   PubMedGoogle Scholar
• Reichel , MP and Pfeiffer , DU . 2002 . An analysis of the performance characteristics of serological tests for the diagnosis of Neospora caninum infection in cattle . Veterinary Parasitology ,
   Google Scholar
• Ruiz , A and Frenkel , JK . 1980 . Toxoplasma gondii in Costa Rican cats . American Journal of Tropical Medicine and Hygiene , 19 : 1150 – 1160 .
   Google Scholar
• Schares , G , Peters , M , Wurm , R , Barwald , A and Conraths , FJ . 1998 . The efficiency of vertical transmission of Neospora caninum in dairy cattle analysed by serological techniques . Veterinary Parasitology , 80 : 87 – 98 .
   PubMed Web of Science ®Google Scholar
• Schares , G , Conraths , FJ and Reichel , MP . 1999 . Bovine neosporosis: comparison of serological methods using outbreak sera from a dairy herd in New Zealand . International Journal for Parasitology , 29 : 1669 – 1676 .
   PubMedGoogle Scholar
• Thornton , RN , Thompson , EJ and Dubey , JP . 1991 . Neospora abortion in New Zealand cattle . New Zealand Veterinary Journal , 39 : 129 – 133 .
   PubMed Web of Science ®Google Scholar
• Thornton , RN , Gajadhar , A and Evans , J . 1994 . Neospora abortion epidemic in a dairy herd . New Zealand Veterinary Journal , 42 : 190 – 191 .
   PubMed Web of Science ®Google Scholar
• Thurmond , M and Hietala , S . 1995 . Strategies to control Neospora infection in cattle . Bovine Practitioner , 29 : 60 – 63 .
   Google Scholar
• Thurmond , MC and Hietala , SK . 1996 . Culling associated with Neospora caninum infection in dairy cows . American Journal of Veterinary Research , 57 : 1559 – 1562 .
   PubMedGoogle Scholar
• Thurmond , MC and Hietala , SK . 1997 . Effect of Neospora caninum infection on milk production in first-lactation dairy cows . Journal of the American Veterinary Medical Association , 210 : 672 – 672 .
   PubMedGoogle Scholar
• Trees , AJ , Davison , HC , Innes , EA and Wastling , JM . 1999 . Towards evaluating the economic impact of bovine neosporosis . International Journal for Parasitology , 29 : 1195 – 1200 .
   PubMedGoogle Scholar
• Trees , AJ , McAllister , MM , Guy , CS , Smith , R and Williams , DJL . 2001 . “ Oral infection of pregnant cows with Neospora caninum oocysts ” . In Neospora 2001. A Symposium On All Aspects of Bovine Neosporosis , Edited by: Buxton , D , Innes , E , Maley , S , Wright , S , Rae , A , Bartley , P , Curran , C and Noble , S . 25 – 25 . Edinburgh : Moredun Research Institute .
   Google Scholar
• Uggla , A , Stenlund , S , Holmdahl , OJM , Jakubek , EB , Thebo , P , Kindahl , H and Björkman , C . 1998 . Oral Neospora caninum inoculation of neonatal calves . International Journal for Parasitology , 28 : 1467 – 1472 .
   PubMed Web of Science ®Google Scholar
• Wallach , M . 1997 . The importance of transmission-blocking immunity in the control of infections by apicomplexan parasites . International Journal for Parasitology , 27 : 1159 – 1167 .
   PubMed Web of Science ®Google Scholar
• Williams , DJ , Guy , CS , McGarry , JW , Guy , F , Tasker , L , Smith , RF , MacEachern , K , Cripps , PJ , Kelly , DF and Trees , AJ . 2000 . Neospora caninum-associated abortion in cattle: the time of experimentally-induced parasitaemia during gestation determines foetal survival . Parasitology , 121 : 347 – 358 .
   PubMedGoogle Scholar
• Woods , LW , Anderson , ML , Swift , PK and Sverlow , KW . 1994 . Systemic neosporosis in a California black-tailed deer (Odocoileus hemionus columbianus) . Journal of Veterinary Diagnostic Investigation , 6 : 508 – 510 .
   PubMedGoogle Scholar
• Wouda , W , Moen , AR , Visser , IJR , Knapen , Fv and Van Knapen , F . 1997 . Bovine fetal neosporosis: a comparison of epizootic and sporadic abortion cases and different age classes with regard to lesion severity and immunohistochemical identification of organisms in brain, heart, and liver . Journal of Veterinary Diagnostic Investigation , 9 : 180 – 185 .
   PubMed Web of Science ®Google Scholar
• Wouda , W , Moen , AR and Schukken , YH . 1998 . Abortion risk in progeny of cows after a Neospora caninum epidemic . Theriogenology , 49 : 1311 – 1316 .
   PubMed Web of Science ®Google Scholar
• Wouda , W , Dijkstra , T , Kramer , AMH , van Maanen , C and Brinkhof , JMA . 1999 . Seroepidemiological evidence for a relationship between Neospora caninum infections in dogs and cattle . International Journal for Parasitology , 29 : 1677 – 1682 .
   PubMed Web of Science ®Google Scholar
• Wren , G . 2000 . Turning a Neospora-infected herd around . Bovine Veterinarian May/June , : 22 – 30 .
   Google Scholar