440
Views
4
CrossRef citations to date
0
Altmetric
Scientific Articles

Treatment with potassium bromide mitigates ataxia and reduces tremor in lambs with perennial ryegrass toxicosis

, , , ORCID Icon, , , , & show all
Pages 287-294 | Received 03 Jan 2019, Accepted 25 Jun 2019, Published online: 14 Jul 2019

References

  • Alvarez-Leefmans FJ, Gamino SM, Giraldez F, Nogueron I. Intracellular chloride regulation in amphibian dorsal root ganglion neurones studied with ion-selective microelectrodes. Journal of Physiology 406, 225–46, 1988 doi: 10.1113/jphysiol.1988.sp017378
  • Baird-Heinz HE, Van Schoick AnL, Pelsor FR, Ranivand L, Hungerford LL. A systematic review of the safety of potassium bromide in dogs. Journal of the American Veterinary Medical Association 240, 705–15, 2012 doi: 10.2460/javma.240.6.705
  • Bertolani C, Hernandez J, Gomes E, Cauzinille L, Poujade A, Gabriel A. Bromide-associated lower airway disease: a retrospective study of seven cats. Journal of Feline Medicine and Surgery 14, 591–7, 2012 doi: 10.1177/1098612X12445069
  • Boothe DM, George KL, Couch P. Disposition and clinical use of bromide in cats. Journal of the American Veterinary Medical Association 221, 1131–5, 2002 doi: 10.2460/javma.2002.221.1131
  • Bowery NG, Hudson AL, Price GW. GABAA and GABAB receptor site distribution in the rat central nervous system. Neuroscience 20, 365–83, 1987 doi: 10.1016/0306-4522(87)90098-4
  • Brown JL, Wasser SK, Wildt DE, Graham LH. Comparative aspects of steroid hormone metabolism and ovarian activity in felids, measured noninvasively in feces. Biology of Reproduction 51, 776–86, 1994
  • Combs M, Edwards SH, Scherpenhuizen JM, Narayan EJ, Kessell AE, Piltz J, Raidal, SR, Ramsay J, Quinn JC. Development of a model for investigation of perennial ryegrass toxicosis in sheep. New Zealand Veterinary Journal 66, 281–9, 2018 doi: 10.1080/00480169.2018.1492986
  • Combs M, Rendell D, Reed K, Mace W, Quinn J. Evidence of dehydration and electrolyte disturbances in cases of perennial ryegrass toxicosis in Australian sheep. Australian Veterinary Journal 92, 107–13, 2014 doi: 10.1111/avj.12161
  • Dell'Orco JM, Wasserman AH, Chopra R, Ingram MAC, Hu Y-S, Singh V, Wulff, H, Opal P, Orr HT, Shakkottai VG. Neuronal atrophy early in degenerative ataxia is a compensatory mechanism to regulate membrane excitability. The Journal of Neuroscience 35, 11292–307, 2015 doi: 10.1523/JNEUROSCI.1357-15.2015
  • Friedlander WJ. Who was ‘the father of bromide treatment of epilepsy’? Archives of Neurology 43, 505–7, 1986 doi: 10.1001/archneur.1986.00520050077027
  • Imlach WL, Finch SC, Zhang Y, Dunlop J, Dalziel JE. Mechanism of action of lolitrem B, a fungal endophyte derived toxin that inhibits BK large conductance Ca2+-activated K+ channels. Toxicon 57, 686–94, 2011 doi: 10.1016/j.toxicon.2011.01.013
  • Johnstone LK, Mayhew IG, Fletcher LR. Clinical expression of lolitrem B (perennial ryegrass) intoxication in horses. Equine Veterinary Journal 44, 304–9, 2012 doi: 10.1111/j.2042-3306.2011.00439.x
  • Kaufmann WA, Ferraguti F, Fukazawa Y, Kasugai Y, Shigemoto R, Laake P, Sexton JA, Ruth P, Wietzorrek G, Knaus H-G, et al. Large-conductance calcium-activated potassium channels in Purkinje cell plasma membranes are clustered at sites of hypolemmal microdomains. Journal of Comparative Neurology 515, 215–30, 2009 doi: 10.1002/cne.22066
  • Kluger E, Malik R, Govendir M. Veterinarians’ preferences for anticonvulsant drugs for treating seizure disorders in dogs and cats. Australian Veterinary Journal 87, 445–9, 2009 doi: 10.1111/j.1751-0813.2009.00509.x
  • March PA, Podell M, Sams RA. Pharmacokinetics and toxicity of bromide following high-dose oral potassium bromide administration in healthy Beagles. Journal of Veterinary Pharmacology and Therapeutics 25, 425-32, 2002 doi: 10.1046/j.1365-2885.2002.00440.x
  • Meierkord H, Grünig F, Gutschmidt U, Gutierrez R, Pfeiffer M, Draguhn A, Brückner C, Heinemann U. Sodium bromide: effects on different patterns of epileptiform activity, extracellular pH changes and GABAergic inhibition. Naunyn-Schmiedeberg's Archives of Pharmacology 361, 25–32, 2000 doi: 10.1007/s002109900162
  • Narayan EJ, Webster K, Nicolson V, Mucci A, Hero J-M. Non-invasive evaluation of physiological stress in an iconic Australian marsupial: the koala (Phascolarctos cinereus). General and Comparative Endocrinology 187, 39–47, 2013 doi: 10.1016/j.ygcen.2013.03.021
  • Nuki G, Richardson P, Goggin MJ, Bayliss RI. Four cases of bromism. British Medical Journal 2, 390–1, 1966 doi: 10.1136/bmj.2.5510.390
  • Philippe G. Lolitrem B and indole diterpene alkaloids produced by endophytic fungi of the genus Epichloë and their toxic effects in livestock. Toxins 8, 47, 2016 doi: 10.3390/toxins8020047
  • Podell M, Fenner WR. Bromide therapy in refractory canine idiopathic epilepsy. Journal of Veterinary Internal Medicine 7, 318-27, 1993 doi: 10.1111/j.1939-1676.1993.tb01025.x
  • Quast TA, Combs MD, Edwards SH. Pharmacokinetics of bromide in adult sheep following oral and intravenous administration. Australian Veterinary Journal 93, 20-5, 2015 doi: 10.1111/avj.12285
  • Reed KFM, Cummins LJ, Moore DD, Clark AJ. Performance of Coopworth ewe lambs exposed to low levels of ryegrass endophyte (Neotyphodium lolii) alkaloids and allowed access to a mycotoxin deactivator. Animal Production Science 51, 225–32, 2011 doi: 10.1071/AN10090
  • Sausbier M, Hu H, Arntz C, Feil S, Kamm S, Adelsberger H, Sausbier U, Sailer CA, Feil R, Hofmann F, et al. Cerebellar ataxia and Purkinje cell dysfunction caused by Ca2+-activated K+ channel deficiency. Proceedings of the National Academy of Sciences of the United States of America 101, 9474–8, 2004 doi: 10.1073/pnas.0401702101
  • Sausbier U, Sausbier M, Sailer C, Arntz C, Knaus H-G, Neuhuber W, Ruth P. Ca-activated K channels of the BK-type in the mouse brain. Histochemistry and Cell Biology 125, 725–41, 2006 doi: 10.1007/s00418-005-0124-7
  • Somogyi P, Takagi H, Richards J, Mohler H. Subcellular localization of benzodiazepine/GABAA receptors in the cerebellum of rat, cat, and monkey using monoclonal antibodies. The Journal of Neuroscience 9, 2197–209, 1989 doi: 10.1523/JNEUROSCI.09-06-02197.1989
  • Suzuki S, Kawakami K, Nakamura F, Nishimura S, Yagi K, Seino M. Bromide, in the therapeutic concentration, enhances GABA-activated currents in cultured neurons of rat cerebral cortex. Epilepsy Research 19, 89–97, 1994 doi: 10.1016/0920-1211(94)90019-1

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.