Plasma pharmacokinetics of a liver-selective nitric oxide-donating diazeniumdiolate in the male C57BL/6 mouse

References

• ANNICH, G. M., MEINHARDT, J. P., MOWERY, K. A., ASHTON, B. A., MERZ, S. I., HIRSCHL, R. B., MEYERHOFF, M. E. and BARTLETT, R. H., 2000, Reduced platelet activation and thrombosis in extracorporeal circuits coated with nitric oxide release polymers. Critical Care Medicine, 28, 915–920.
   PubMed Web of Science ®Google Scholar
• CHEN, C., HANSON, S. R., KEEFER, L. K., SAAVEDRA, J. E., DAVIES, K. M., HUTSELL, T. C., HUGHES, J. D., Ku, D. N. and LUMSDEN, A. B., 1997, Boundary layer infusion of nitric oxide reduces early smooth muscle cell proliferation in the endarterectomized canine artery. Journal of Surgical Research, 67, 26–32.
   PubMed Web of Science ®Google Scholar
• ESPADAS-TORRE, C., OKLEJAS, V., MOWERY, K. and MEYERHOFF, M. E., 1997, Thromboresistant chemical sensors using combined nitric oxide release/ion sensing polymeric films. Journal of the American Chemical Society, 119, 2321–2322.
   Google Scholar
• FEELISCH, M. and STAMLER, J. S., 1996, Donors of nitrogen oxides. In M. Feelisch and J. S. Stamler (eds), Methods in Nitric Oxide Research (New York: Wiley), pp. 71–115.
   Google Scholar
• HANSON, S. R., HUTSELL, T. C., KEEFER, L. K., MOORADIAN, D. L. and SMITH, D. J., 1995, Nitric oxide donors: a continuing opportunity in drug design. Advances in Pharmacology, 34, 383-398. KEEFER, L. K., 2000, Design of nitric oxide-releasing drugs. Pharmaceutical News, 7, 27–32.
   Google Scholar
• KEEFER, L. K., Nims, R. W., DAVIES, K. M. and WINK, D. A., 1996, `NONOates' (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms. Methods in Enzymology, 268, 281–293.
   PubMed Web of Science ®Google Scholar
• GILLETTE, J. R. and PANG, K. S., 1977, Theoretic aspects of pharmacokinetic drug interactions. Clinical Pharmacology and Therapeutics, 22, 623–639.
   PubMed Web of Science ®Google Scholar
• LEHMANN, J., 2000, Nitric oxide donors — current trends in therapeutic applications. Expert Opinion on Therapeutic Patents, 10, 579–594.
   Google Scholar
• LIU, J., SAAVEDRA, J. E., Lu, T., SONG, J.-G., WAALKES, M. P. and KEEFER, L. K., 2002, The liver-selective nitric oxide donor, V-PYRRO/NO, protects against d-galactosamine/endotoxin-induced hepatotoxicity in mice. Journal of Pharmacology and Experimental Therapeutics, 300, 1–8.
   Google Scholar
• LUKAS, G., BRINDLE, S. D. and GREENGARD, P., 1971, The route of absorption of intraperitoneally administered compounds. Journal of Pharmacology and Experimental Therapeutics, 178, 562–566.
   PubMed Web of Science ®Google Scholar
• MARAGOS, C. M., MORLEY, D., WINK, D. A., DUNAMS, T. M., SAAVEDRA, J. E., HOFFMAN, A., Bow, A. A., ISAAC, L., HRABIE, J. A. and KEEFER, L. K., 1991, Complexes of NO with nucleophiles as agents for the controlled biological release of nitric oxide. Vasorelaxant effects. Journal of Medicinal Chemistry, 34, 3242–3247.
   PubMed Web of Science ®Google Scholar
• MOWERY, K. A., SCHOENSCH, M. H., SAAVEDRA, J. E., KEEFER, L. K. and MEYERHOFF, M. E., 2000, Preparation and characterization of hydrophobic polymeric films that are thromboresistant via nitric oxide release. Biomaterials, 21, 9–21.
   PubMed Web of Science ®Google Scholar
• NICKERSON, D. F. and TOLER, S. M., 1997, Intraperitoneal and intraportal administration of droloxifene to the Sprague—Dawley rat: assessing the first-pass effect. Xenobiotica, 27, 627–632.
   PubMed Web of Science ®Google Scholar
• NOTARI, R. E., 1987, Biopharmaceutics and Clinical Pharmacokinetics (New York: Marcel Dekker).
   Google Scholar
• Ou, J., CARLOS, T. M., WATKINS, S. C., SAAVEDRA, J. E., KEEFER, L. K., KIM, Y.-M., HARBRECHT, B. G. and BILLIAR, T. R., 1997, Differential effects of nonselective nitric oxide synthase (NOS) and selective inducible NOS inhibition on hepatic necrosis, apoptosis, ICANI-1 expression, and neutrophil accumulation during endotoxemia. Nitric Oxide: Biology and Chemistry, 1, 404–416.
   Google Scholar
• PANG, K. S. and GILLETTE, J. R., 1978, Complications in the estimation of hepatic blood flow in vivo by pharmacokinetic parameters. The area under the curve after the concomitant intravenous and intraperitoneal (or intraportal) administration of acetaminophen in the rat. Drug Metabolism and Disposition, 6, 566–576.
   PubMedGoogle Scholar
• PLUTA, R. M., OLDFIELD, E. H. and BOOCK, R. J., 1997, Reversal and prevention of cerebral vasospasm by intracarotid infusions of nitric oxide donors in a primate model of subarachnoid hemorrhage. Journal of Neurosurgery, 87, 746–751.
   PubMed Web of Science ®Google Scholar
• RICCIARDI, R., FOLEY, D. P., QUARFORDT, S. H., SAAVEDRA, J. E., KEEFER, L. K., WHEELER, S. M., DONOHUE, S. E., CALLERY, M. P. and MEYERS, W. C., 2001, V-PYRRO/NO: an hepato-selective nitric oxide donor improves porcine liver hemodynamics and function after ischemia reperfusion. Transplantation, 71, 193–198.
   PubMedGoogle Scholar
• SAAVEDRA, J. E., BILLIAR, T. R., WILLIAMS, D. L., KIM, Y.-M., WATKINS, S. C. and KEEFER, L. K., 1997, Targeting nitric oxide (NO) delivery in vivo. Design of a liver-selective NO donor prodrug that blocks tumor necrosis factor-a-induced apoptosis and toxicity in the liver. Journal of Medicinal Chemistry, 40, 1947–1954.
   Google Scholar
• SAAVEDRA, J. E., SOUTHAN, G. J., DAVIES, K. M., LUNDELL, A., MARKOU, C., HANSON, S. R., ADRIE, C., HURFORD, W. E., ZAPOL, W. M. and KEEFER, L. K., 1996, Localizing antithrombotic and vasodilatory activity with a novel, ultrafast nitric oxide donor. Journal of Medicinal Chemistry, 39, 4361–4365.
   PubMed Web of Science ®Google Scholar
• SHARGEL, L. and Yu, A. B. C. 1985, Applied Biopharmaceutics and Pharmacokinetics (Norwalk: Appleton-Century-Crofts).
   Google Scholar
• SMITH, D. J., CHAKRAVARTHY, D., PULFER, S., SIMMONS, M. L., HRABIE, J. A., CITRO, M. L., SAAVEDRA, J. E., DAVIES, K. M., HUTSELL, T. C., MOORADIAN, D. L., HANSON, S. R. and KEEFER, L. K., 1996, Nitric oxide-releasing polymers containing the [N(0)NO] group. Journal of Medicinal Chemistry, 39, 1148–1156.
   PubMed Web of Science ®Google Scholar