References
- ARELLANO, M., MALET-MARTINO, M., MARTINO, R. and SPECTOR, T., 1997, 5-ethynyluracil (GW776): effects on the formation of the toxic catabolites of 5-fluorouracil, fluoroacetate and fluorohydroxypropionic acid in the isolated perfused rat liver model. British Journal of Cancer, 76, 1170–1180.
- ASHWELL, G. and MORELL, A. G., 1974, The role of surface carbohydrates in the hepatic recognition and transport of circulating glycoproteins. Advances in Enzymology and Related Areas of Molecular Biology, 41, 99–128.
- BERRY, J. P., CHAINTREAU, M., CHASSOUX, D., DENNEBOUY, R., ESCAIG, F., CALLE, P., ROSSIGNOL, J. M., SLODZIAN, G. and TwuzEAu, S., 1994, Advantages of the scanning ion microscopy for mapping halogen corticoids in normal and transformed cells in culture. Biology of the Cell, 81, 65–72.
- CASTLE, M. C., 1993, Formation of a 13-glucuronidase-resistant glucuronide conjugate of digitoxin by dog liver micro somes. Drug Metabolism and Disposition, 21, 1147–1150.
- DEAR, G. J., IsmAIL, I. M., MUTCH, P. J., PLUMB, R .S., DAVIES, L. H. and SWEATMAN, B. C., 2000, Urinary metabolites of a novel quinoxaline non-nucleoside reverse transcriptase inhibitor in rabbit, mouse and human: identification of fluorine NIH shift metabolites using NMR and tandem MS. Xenobiotica, 30, 407–426.
- FEOFANOV, A., CHARONOV, S., FLEURY, F., KUDELINA, I., JARDILLIER, J. C. and NABIEV, I., 1999, Confocal spectral imaging analysis of intracellular interactions of mitoxantrone at different phases of the cell cycle. Anticancer Research, 19, 5341–5348.
- IsmAiL, I. M., DEAR, G. J., ROBERTS, A. D., PLUMB, R. S., AYRTONT, J., SWEATMAN, B. C. and BOWERS, G. D., 2002, N-0 glucuronidation: a major human metabolic pathway in the elimination of two novel anti-convulsant drug candidates. Xenobiotica, 32, 29–43.
- LODISH, H. F., 1991, Recognition of complex oligosaccharides by the multi-subunit asialoglycoprotein receptor. Trends in Biochemical Sciences, 16, 374–377.
- MALET-MARTINO, M. C., ARMAND, J. P., LOPEZ, A., BERNADOU, J., BETEILLE, J. P., BON, M. and MARTINO, R., 1986, Evidence for the importance of 5'-deoxy-5-fluorouridine catabolism in humans from 19F nuclear magnetic resonance spectrometry. Cancer Research, 46, 2105–2112.
- MALET-MARTINO, M. C. and MARTINO, R., 1992, Magnetic resonance spectroscopy: a powerful tool for drug metabolism studies. Biochimie, 74, 785–800.
- MARTINO, R., MALET-MARTINO, M. and GILARD, V., 2000, Fluorine nuclear magnetic resonance, a privileged tool for metabolic studies of fiuoropyrimidine drugs. Current Drug Metabolism, 1, 271–303.
- MARTINO, R., MALET-MARTINO, M. C., VIALANEIX, C., LOPEZ, A. and BON, M., 1987, 19F nuclear magnetic resonance analysis of the carbamate reaction of cc-fluoro-13-alanine (FBAL), the major catabolite of fiuoropyrimidines. Application to FBAL carbamate determination in body fluids of patients treated with 5'-deoxy-5-fluorouridine. Drug Metabolosm and Disposition, 15, 897–904.
- Mu, J. Z., GORDON, M., SHAO, J. S. and ALPERS, D. H., 1997, Apical expression of functional asialoglycoprotein receptor in the human intestinal cell line HT-29. Gastroenterology, 113, 1501–1509.
- NAKABAYASHI, H., TAKETA, K., MIYANO, K., YAMANE, T. and SATO, J., 1982, Growth of human hepatoma cells lines with differentiated functions in chemically defined medium. Cancer Research, 42, 3858–3863.
- PARISOT, D., MALET-MARTINO, M. C., MARTINO, R. and CRASNIER, P., 1991, 19F nuclear magnetic resonance analysis of 5-fluorouracil metabolism in four differently pigmented strains of Nectria haematococca. Applied and Environmental Microbiology, 57, 3605–3612.
- PINEDO, H. M. and PETERS, G. J., 1988, Fluorouracil: biochemistry and pharmacology. Journal of Clinical Oncology, 6, 1653–1664.
- ROBERTS, A., RENWICK, A. G., Sims, J. and SNODIN, D. J., 2000, Sucralose metabolism and pharmacokinetics in man. Food Chemistry and Toxicology, 38 (Suppl. 2), S31—S41.
- ROHLFF, C., HOLT, G., COURTNEY, S. and TREPEL, J., 1997, Enhanced liver specific activity of a glycan-conjugated 5-FU for the treatment of hepatocellular cancer. Proceedings of the American Association for Cancer Research, 38, abst 698.
- ROHLFF, C., WATSON, S. A., MORRIS, T. M., SKELTON, L., JACKMAN, A. L. and PAGE, M. J., 1999, A novel, orally administered nucleoside analogue, OGT 719, inhibits the liver invasive growth of a human colorectal tumor, C17OHM2. Cancer Research, 59, 1268–1272.
- SCARFE, G. B., WRIGHT, B., CLAYTON, E., TAYLOR, S., WILSON, I. D., LINDON, J. C. and NICHOLSON, J. K., 1999, Quantitative studies on the urinary metabolic fate of 2-chloro-4-trifluoromethylani-line in the rat using 19F-NMR spectroscopy and directly coupled HPLC-NMR-MS. Xenobiotica, 29, 77–91.
- SCHWARTZ, A. L., FRIDOVICH, S. E., KNOWLES, B. B. and LODISH, H. F., 1981, Characterization of the asialoglycoprotein receptor in a continuous hepatoma line. Journal of Biological Chemistry, 256, 8878–8881.
- SHARMA, R. A., EATOCK, M. M., TWELVES, C. J., BROWN, G., MCLELLAND, H. R., CLAYTON, K. T., O'BYRNE, K. J., MOYSES, C., CARMICHAEL, J. and STEWARD, W. P., 2001, Bioavailability study of oral and intravenous OGT 719, a novel nucleoside analogue with preferential activity in the liver. Cancer Chemotherapy and Pharmacology, 48, 197–201.
- WAIN, W. H. and STAATZ, W. D., 1973, Rates of synthesis of ribosomal protein and total ribonucleic acid through the cell cycle of the fission yeast Schizosaccharomyces pombe. Experimental Cell Research, 81, 269–278.
- WEISS, P. and ASHWELL, G., 1989, The asialoglycoprotein receptor: properties and modulation by ligand. Progress in Clinical Biology Research, 300, 169–184.
- WOOD, S. G., JOHN, B. A. and HAWKINS, D. R., 2000, The pharmacokinetics and metabolism of sucralose in the dog. Food and Chemical Toxicology, 38 (Suppl. 2), S99–5106.