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Xenobiotica
the fate of foreign compounds in biological systems
Volume 35, 2005 - Issue 1
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Research Article

Cytochrome P450-dependent metabolism of gefitinib

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Pages 39-50 | Received 25 Aug 2004, Published online: 22 Sep 2008

References

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  • Baselga J, Rischin D, Ranson M, Calvert H, Raymond E, Kieback DG, Kaye SB, Gianni L, Harris A, Bjork T, Averbuch SD, Feyereislova A, Swaisland H, Rojo F, Albanell J. 2002. Phase I safety, pharmacokinetics, and pharmacodynamic trial of ZD1839, a selective oral epidermal growth factor receptor tyrosine kinase inhibitor, in patients with five selected solid tumor types. Journal of Clinical Oncology 20:4292-4302.
  • Ciardiello F, Tortora G. 2002. Anti-epidermal growth factor receptor drugs in cancer therapy. Expert Opinion on Investigational Drugs 11:755-768.
  • De Wildt SN, Kearns GL, Leeder JS, Van den Anker JN. 1999. Cytochrome P450 3A. Ontogeny and drug disposition. Clinical Pharmacokinetics 37:485-505.

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