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Xenobiotica
the fate of foreign compounds in biological systems
Volume 38, 2008 - Issue 6
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Original Articles

Inhibition of P-glycoprotein in Caco-2 cells: Effects of herbal remedies frequently used by cancer patients

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Pages 559-573 | Received 03 Jan 2008, Accepted 13 Feb 2008, Published online: 22 Sep 2008

References

  • Adachi, Y , Suzuki, H , and Sugiyama, Y , 2001. Comparative studies on in vitro methods for evaluating in vivo function of MDR1 P-glycoprotein , Pharmaceutical Research 18 (2001), pp. 1660–1668.
  • Arunkumar, A , Vijayababu, MR , Srinivasan, N , Aruldhas, MM , and Arunakaran, J , 2006. Garlic compound, diallyl disulfide induces cell cycle arrest in prostate cancer cell line PC-3 , Molecular Cell Biochemistry 288 (2006), pp. 107–113.
  • Balayssac, D , Authier, N , Cayre, A , and Coudore, F , 2005. Does inhibition of P-glycoprotein lead to drug–drug interactions? Toxicology Letters 156 (2005), pp. 319–329.
  • Bansal, T , Singh, M , Mishra, G , Talegaonkar, S , Khar, RK , Jaggi, M , and Mukherjee, R , 2007. Concurrent determination of topotecan and model permeability markers (atenolol, antipyrine, propranolol and furosemide) by reversed phase liquid chromatography: Utility in Caco-2 intestinal absorption studies , Journal of Chromatography B Analytical Technology, Biomedicine and Life Sciences 859 (2007), pp. 261–266.
  • Bauer, S , Stormer, E , Johne, A , Kruger, H , Budde, K , Neumayer, HH , Roots, I , and Mai, I , 2003. Alterations in cyclosporin A pharmacokinetics and metabolism during treatment with St John's wort in renal transplant patients , Br Journal of Clinical Pharmacology 55 (2003), pp. 203–211.
  • Beijnen, JH , and Schellens, JH , 2004. Drug interactions in oncology , Lancet Oncology 5 (2004), pp. 489–496.
  • Beulz-Riche, D , Robert, J , Riche, C , and Ratanasavanh, D , 2002. Effects of paclitaxel, cyclophosphamide, ifosfamide, tamoxifen and cyclosporine on the metabolism of methoxymorpholinodoxorubicin in human liver microsomes , Cancer Chemotherapy and Pharmacology 49 (2002), pp. 274–280.
  • Boon, HS , Olatunde, F , and Zick, SM , 2007. Trends in complementary/alternative medicine use by breast cancer survivors: Comparing survey data from 1998 and 2005. BMC Women's Health 7:4 doi:10.1186/1472-6874-7-4 , (2007).
  • Braun, A , Hammerle, S , Suda, K , Rothen-Rutishauser, B , Gunthert, M , Kramer, SD , and Wunderli-Allenspach, H , 2000. Cell cultures as tools in biopharmacy , European Journal of Pharmaceutical Science 11 (Suppl. 2) (2000), pp. S51–S60.
  • Collett, A , Tanianis-Hughes, J , Carlson, GL , Harwood, MD , and Warhurst, G , 2005. Comparison of P-glycoprotein-mediated drug–digoxin interactions in Caco-2 with human and rodent intestine: Relevance to in vivo prediction , European Journal of Pharmaceutical Science 26 (2005), pp. 386–393.
  • Dahlin, KL , Bohlin, K , Strindlund, J , Ryrfeldt, A , and Cotgreave, IA , 1999. Amitriptyline-induced loss of tight junction integrity in a human endothelial — smooth muscle cell bi-layer model , Toxicology 136 (1999), pp. 1–13.
  • Eizenberg, DM , Davis, RB , Ettner, SL , Appel, S , Wilkey, S , Van, RM , and Kessler, RC , 1998. Trends in alternative medicine use in the United States, 1990–1997: Results of a follow-up national survey , Journal of the American Medical Association 280 (1998), pp. 1569–1575.
  • Engdal, S , Steinsbekk, A , Klepp, O , and Nilsen, OG , 2007. Herbal use among cancer patients during palliative or curative chemotherapy treatment in Norway . 2007, Support Care Cancer, DOI 10.1007/s00520-007-0371-3.
  • Foster, BC , Foster, MS , Vandenhoek, S , Krantis, A , Budzinski, JW , Arnason, JT , Gallicano, KD , and Choudri, S , 2001. An in vitro evaluation of human cytochrome P450 3A4 and P-glycoprotein inhibition by garlic , Journal of Pharmacy and Pharmacology 4 (2001), pp. 176–184.
  • Hall, SD , Wang, Z , Huang, SM , Hamman, MA , Vasavada, N , Adigun, AQ , Hilligoss, JK , Miller, M , and Gorski, JC , 2003. The interaction between St John's wort and an oral contraceptive , Clinical Pharmacology and Therapeutics 74 (2003), pp. 525–535.
  • Hayeshi, R , Masimirembwa, C , Mukanganyama, S , and Ungell, AL , 2006. The potential inhibitory effect of antiparasitic drugs and natural products on P-glycoprotein mediated efflux , European Journal of Pharmaceutical Science 29 (2006), pp. 70–81.
  • Hellum, BH , 2007. "In vitro interactions between medicinal drugs and herbs on cytochrome P-450 metabolism and P-glycoprotein transport". In: Dissertation . Trondheim: Norwegian University of Science and Technology; 2007.
  • Hellum, BH , Hu, Z , and Nilsen, OG , 2007. The induction of CYP1A2, CYP2D6 and CYP3A4 by six trade herbal products in cultured primary human hepatocytes , Basic Clinical Pharmacology and Therapeutics 100 (2007), pp. 23–30.
  • Hu, Z , Yang, X , Ho, PC , Chan, SY , Heng, PW , Chan, E , Duan, W , Koh, HL , and Zhou, S , 2005. Herb–drug interactions: A literature review , Drugs 65 (2005), pp. 1239–1282.
  • Ikeda, Y , Iki, M , Morita, A , Kajita, E , Kagamimori, S , Kagawa, Y , and Yoneshima, H , 2006. Intake of fermented soybeans, natto, is associated with reduced bone loss in postmenopausal women: Japanese population-based osteoporosis (JPOS) study , Journal of Nutrition 136 (2006), pp. 1323–1328.
  • Ioannides, C , 2002. Pharmacokinetic interactions between herbal remedies and medicinal drugs , Xenobiotica 32 (2002), pp. 451–478.
  • Jakubikova, J , and Sedlak, J , 2006. Garlic-derived organosulfides induce cytotoxicity, apoptosis, cell cycle arrest and oxidative stress in human colon carcinoma cell lines , Neoplasma 53 (2006), pp. 191–199.
  • Keogh, JP , and Kunta, JR , 2006. Development, validation and utility of an in vitro technique for assessment of potential clinical drug–drug interactions involving P-glycoprotein , European Journal of Pharmaceutical Sciences 27 (2006), pp. 543–554.
  • Kitagawa, S , 2004. Inhibition of P-glycoprotein function by tea catechins in KB-C2 cells , Journal of Pharmacy and Pharmacology 56 (2004), pp. 1001–1005.
  • Lawson, LD , and Gardner, CD , 2005. Composition, stability, and bioavailability of garlic products used in a clinical trial , Journal of Agricultural and Food Chemistry 3 (2005), pp. 6254–6261.
  • Leveque, D , and Jehl, F , 2007. Molecular pharmacokinetics of catharanthus (vinca) alkaloids , Journal of Clinical Pharmacology 47 (2007), pp. 579–588.
  • Li, X , and Choi, JS , 2007. Effect of genistein on the pharmacokinetics of paclitaxel administered orally or intravenously in rats , International Journal of Pharmaceutics 337 (2007), pp. 188–193.
  • Lim, SL , and Lim, LY , 2006. Effects of citrus fruit juices on cytotoxicity and drug transport pathways of Caco-2 cell monolayers , International Journal of Pharmaceutics 307 (2006), pp. 42–50.
  • Molassiotis, A , Fernadez-Ortega, P , Pud, D , Ozden, G , Scott, JA , Panteli, V , Margulies, A , Browall, M , Magri, M , Selvekerova, S , et al., 2005. Use of complementary and alternative medicine in cancer patients: A European survey , Annals of Oncology 16 (2005), pp. 655–663.
  • Moschella, C , and Jaber, BL , 2001. Interaction between cyclosporine and Hypericum perforatum (St. John's wort) after organ transplantation , American Journal of Kidney Diseases 38 (2001), pp. 1105–1107.
  • Nabekura, T , Kamiyama, S , and Kitagawa, S , 2005. Effects of dietary chemopreventive phytochemicals on P-glycoprotein function , Biochemical and Biophysical Research Communications 327 (2005), pp. 866–870.
  • Netsch, MI , Gutmann, H , Luescher, S , Brill, S , Schmidlin, CB , Kreuter, MH , and Drewe, J , 2005. Inhibitory activity of a green tea extract and some of its constituents on multidrug resistance-associated protein 2 functionality , Planta Medica 71 (2005), pp. 135–141.
  • Pauli-Magnus, C , Rekersbrink, S , Klotz, U , and Fromm, MF , 2001. Interaction of omeprazole, lansoprazole and pantoprazole with P-glycoprotein , Naunyn Schmiedebergs Archives in Pharmacology 364 (2001), pp. 551–557.
  • Perva-Uzunalic, A , Skerget, M , Knez, Z , Weinreich, B , Otto, F , and Gruner, S , 2006. Extraction of active ingredients from green tea (Camellia sinensis): Extraction efficiency of major catechins and caffeine , Food Chemistry 96 (2006), pp. 597–605.
  • Sadeque, AJ , Wandel, C , He, H , Shah, S , and Wood, AJ , 2000. Increased drug delivery to the brain by P-glycoprotein inhibition , Clinical Pharmacology and Therapeutics 68 (2000), pp. 231–237.
  • Shapiro, LE , and Shear, NH , 2002. Drug interactions: Proteins, pumps, and P-450s , Journal of American Academy of Dermatology 47 (2002), pp. 467–484.
  • Sparreboom, A , Cox, MC , Acharya, MR , and Figg, WD , 2004. Herbal remedies in the United States: Potential adverse interactions with anticancer agents , Journal of Clinical Oncology 22 (2004), pp. 2489–2503.
  • Tascilar, M , De Jong, FA , Verweij, J , and Mathijssen, RHJ , 2006. Complementary and alternative medicine during cancer treatment: Beyond innocence , Oncologist 11 (2006), pp. 732–741.
  • Thiebaut, F , Tsuruo, T , Hamada, H , Gottesman, MM , Pastan, I , and Willingham, MC , 1987. Cellular localization of the multidrug-resistance gene product P-glycoprotein in normal human tissues , Proceedings of the National Academy of Sciences, USA, 84 (1987), pp. 7735–7738.
  • Verschraagen, M , Koks, CHW , Schellens, JHM , and Beijnen, JH , 1999. P-glycoprotein system as a determinant of drug interactions: The case of digoxin-verapamil , Pharmacological Research 40 (1999), pp. 301–306.
  • Werneke, U , Earl, J , Seydel, C , Horn, O , Crichton, P , and Fannon, D , 2004. Potential health risks of complementary alternative medicines in cancer patients , British Journal of Cancer 90 (2004), pp. 408–413.
  • Zhu, M , Chen, Y , and Li, RC , 2000. Oral absorption and bioavailability of tea catechins , Planta Medica 66 (2000), pp. 444–447.

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