Publication Cover
Xenobiotica
the fate of foreign compounds in biological systems
Volume 38, 2008 - Issue 11
113
Views
2
CrossRef citations to date
0
Altmetric
Research Article

Pharmacokinetics of bicyclol in rats with acute hepatic failure

, , , , &
Pages 1399-1409 | Received 17 Apr 2008, Accepted 08 Sep 2008, Published online: 04 Nov 2008

References

  • Bruno B, Nicole LT, Rachid B, Michel MT. In vitro metabolism and drug interaction potential of a new highly potent anti-cytomegalovirus molecule, CMV423 (2-chloro 3-pyridine 3-yl 5,6,7,8-tetrahydroindolizine 1-carboxamide). British Journal of Clinical Pharmacology 2001; 52: 53–63
  • Castilla C, Prieto J, Urdaneta E, Pascual M, Nuñez M, Zudaire E, Garcia M, Quiroga J, Santidrian S. Impaired intestinal sugar transport in cirrhotic rats: Correction by low doses of insulin-like growth factor I. Gastroenterology 1997; 113: 1180–1187
  • Cummins CL, Salphati L, Reid MJ, Benet LZ. In vivo modulation of intestinal CYP3A metabolism by P-glycoprotein: Studies using the rat single-pass intestinal perfusion model. Journal of Pharmacology and Experimental Therapy 2003; 305: 306–314
  • Hu QW, Liu GT. Effects of bicyclol on dimethylnitrosamine-induced liver fibrosis in mice and its mechanism of action. Life Science 2006; 79: 606–612
  • Huang ZH, Murakami T, Okochi A, Yumoyo R, Nagai J, Takano M. Expression and function of P-glycoprotein in rats with carbon tetrachloride-induced acute hepatic failure. Journal of Pharmacy and Pharmacology 2001; 53: 873–881
  • Johnson BM, Chen WQ, Borchardt RT, Charman WN, Porter CJH. A kinetic evaluation of the absorption, efflux, and metabolism of verapamil in the autoperfused rat jejunum. Journal of Pharmacology and Experimental Therapeutics 2003; 305: 151–158
  • Ju MH, Li Y. Metabolism of bicyclol in rat and human liver microsomes in vitro. Acta Pharmaceutica Sinica 2005; 2: 111–116
  • Li C, Nakayama S, Kurosaki Y, Nakayama T, Kimura T. Pharmacokinetics of cefpiramide in rats acutely intoxicated with carbon tetrachloride. Journal of Pharmacobio-dynamics 1990; 13: 186–194
  • Li Y, Li Y, Liu GT. Protective effects of bicyclol on liver fibrosis induced by carbon tetrachloride. Chinese Medical Journal 2004; 84: 2096–2101
  • Liu GT. The anti-virus and hepatoprotective effect of bicyclol and its mechanism of action. Chinese Journal of New Drugs 2001; 10: 325–327
  • Mahnaz S, Andrew H, Glen BB. Inhibitory effects of the monoamine oxidase inhibitor tranylcypromine on the cytochrome P450 enzymes CYP2C19, CYP2C9, and CYP2D6. Cellular and Molecular Neurobiology 2004; 24: 63–76
  • Okumura H, Katoh M, Minami K, Nakajima M, Yokoi T. Change of drug excretory pathway by CCl4-induced liver dysfunction in rat. Biochemical Pharmacology 2007; 74: 488–495
  • McLean AJ, Morgan DJ. Clinical pharmacokinetics in patients with liver disease. Clinical Pharmacokinetics 1991; 21: 42–69
  • Minami K, Saito T, Narahara M, Tomita H, Kato H, Sugiyama H. Relationship between hepatic gene expression profiles and hepatotoxicity in five typical hepatotoxicant administered rats. Toxicology Science 2005; 87: 296–305
  • Okumura H, Katah M, Minami K, Nakajima M, Yokoi T. Change of drug excretory pathway by ccl4-induced liver dysfunction in rat. Biochemical Pharmacology 2007; 74: 488–495
  • Park EJ, Jeon CH, Ko G, Kim J, Sohn DH. Protective effect of curcumin in rat liver injury induced by carbon tetrachloride. Journal of Pharmacy and Pharmacology 2000; 52: 437–440
  • Reza M, Anjaneya PC. Hepatic disposition of cyclosporine A in isolated perfused rat livers. Journal of Pharmaceutical Sciences 2004; 7: 47–54
  • Savina PM, Staubus AE, Gaginella TS, Smith DF. Optimal perfusion rate determined for in situ intestinal absorption studies in rats. Journal of Pharmaceutical Sciences 1981; 70: 239–243
  • Singhal D, Ho NF, Anderson BD. Absorption and intestinal metabolism of purine dideoxynucleosides and an adenosine deaminase-activated prodrug of 2′,3′-dideoxyinosine in the mesenteric vein cannulated rat ileum. Journal of Pharmaceutical Sciences 1998; 87: 569–577
  • Sugano T, Suda K, Shimada M, Oshino N. Biochemical and ultrastructural evaluation of isolated rat liver systems perfused with a hemoglobin-free medium. Journal of Biochemistry 1978; 83: 995–1007
  • Sugihara N, Furuno K, Kita N, Murakami T, Yata N. Distribution of quinidine in rats with carbon tetrachloride-intoxicated hepatic disease. Journal of Pharmacobio-dynamics 1992; 15: 167–174
  • Tamura S, Ohike A, Tokunaga Y, Ibuki R, Amidon GL, Sezaki H, Yamashita S. Effect of experimental acute renal and hepatic failure on absorption of tacrolimus in rat small intestine. Drug Metabolism and Pharmacokinetics 2004; 3: 190–197
  • Von Moltke LL, Greenblatt DJ, Cotreau BMM, Duan SX, Harmatz JS, Shader RI. Inhibition of desipramine hydroxylation in vitro by serotonin-reuptake-inhibitor antidepressants, and by quinidine and ketoconazole: A model system to predict drug interactions in vivo. Journal of Pharmacology and Experimental Therapeutics 1994; 268: 1278–1283
  • Wang HP, Li Y. Protective effect of bicyclol on acute hepatic failure induced by lipopolysaccharide and D-galactosamine in mice. European Journal of Pharmacology 2006; 534: 194–201
  • Wu CY, Benet LZ. Disposition of tacrolimus in isolated perfused rat liver: Influence of troleandomycin, cyclosporine, and gg918. Drug Metabolism and Disposition 2003; 31: 1292–1295
  • Yao GB, Xu DZh, Lan P, Xu ChB, Wang Ch, Luo J, Shen YM, Li Q. Efficacy and safety of bicyclol in treatment of 2,200 chronic viral hepatitis. Chinese Journal of New Drugs and Clinical Remedies 2005; 24: 421–426
  • Yokogawa K, Watanabe M, Takeshita H, Nomura M, Mano Y, Miyamoto K. Serum aminotransferase activity as a predictor of clearance of drugs metabolized by CYP isoforms in rats with acute hepatic failure induced by carbon tetrachloride. International Journal of Pharmaceutics 2004; 269: 479–489
  • Zhang L, Lin G, Chang Q, Zuo Z. Role of intestinal first-pass metabolism of baicalein in its absorption process. Pharmaceutical Research 2005; 7: 1050–1058

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.