Xenobiotica, Volume 38, Issue 11 (2008)

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Xenobiotica, Volume 38, Issue 11 (2008)

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Obituary

David McKillop BSc, PhD 1951–2008
Pages: 1353-1354
Published online: 04 Nov 2008
CitationforDavid McKillop BSc, PhD 1951–2008 | Full Text | PDF (25.5 KB)
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Research Article

Article
Human CYP3A4-introduced HepG2 cells: In vitro screening system of new chemicals for the evaluation of CYP3A4-inhibiting activity
N. Araki, S. Tsuruoka, N. Wang, G. Hasegawa, H. Yanagihara, H. Ando, T. Omasa, S. Enosawa, H. Nagai & A. Fujimura
Pages: 1355-1364
Published online: 04 Nov 2008
AbstractforHuman CYP3A4-introduced HepG2 cells: In vitro screening system of new chemicals for the evaluation of CYP3A4-inhibiting activity | Full Text | References | PDF (137.4 KB)
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Article
Lack of interaction between metoclopramide and morphine in vitro and in mice
D. Ung, A. Cowan, H. P. Parkman & S. Nagar
Pages: 1365-1376
Published online: 04 Nov 2008
AbstractforLack of interaction between metoclopramide and morphine in vitro and in mice | Full Text | References | PDF (360.2 KB)
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Article
Interspecies scaling of a camptothecin analogue: Human predictions for intravenous topotecan using animal data
P. Ahlawat & N. R. Srinivas
Pages: 1377-1385
Published online: 04 Nov 2008
AbstractforInterspecies scaling of a camptothecin analogue: Human predictions for intravenous topotecan using animal data | Full Text | References | PDF (64.2 KB)
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Article
Determination of microsome and hepatocyte scaling factors for in vitro/in vivo extrapolation in the rat and dog
R. Smith, R. D. O. Jones, P. G. Ballard & H. H. Griffiths
Pages: 1386-1398
Published online: 04 Nov 2008
AbstractforDetermination of microsome and hepatocyte scaling factors for in vitro/in vivo extrapolation in the rat and dog | Full Text | References | PDF (81.8 KB)
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Article
Pharmacokinetics of bicyclol in rats with acute hepatic failure
Wei Tan, Baolian Wang, Jing Zhao, Li Sheng, Jinping Hu & Yan Li
Pages: 1399-1409
Published online: 04 Nov 2008
AbstractforPharmacokinetics of bicyclol in rats with acute hepatic failure | Full Text | References | PDF (120.3 KB)
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Article
Impaired intrinsic chiral inversion activity of ibuprofen in rats with adjuvant-induced arthritis
S. Uno, M. Uraki, H. Komura, H. Ikuta, A. Kawase & M. Iwaki
Pages: 1410-1421
Published online: 04 Nov 2008
AbstractforImpaired intrinsic chiral inversion activity of ibuprofen in rats with adjuvant-induced arthritis | Full Text | References | PDF (113.9 KB)
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Article
Influence of uridine diphosphate (UDP)-glucuronosyltransferases and ABCC2 genetic polymorphisms on the pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant recipients
W.-X. Zhang, B. Chen, Z. Jin, Z. Yu, X. Wang, H. Chen, A. Mao & W. Cai
Pages: 1422-1436
Published online: 04 Nov 2008
AbstractforInfluence of uridine diphosphate (UDP)-glucuronosyltransferases and ABCC2 genetic polymorphisms on the pharmacokinetics of mycophenolic acid and its metabolites in Chinese renal transplant recipients | Full Text | References | PDF (88.3 KB)
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Article
Assessing and minimizing time-dependent inhibition of cytochrome P450 3A in drug discovery: A case study with melanocortin-4 receptor agonists
W. Tang, R. A. Stearns, R. W. Wang, R. R. Miller, Q. Chen, J. Ngui, R. K. Bakshi, R. P. Nargund, D. C. Dean & T. A. Baillie
Pages: 1437-1451
Published online: 04 Nov 2008
AbstractforAssessing and minimizing time-dependent inhibition of cytochrome P450 3A in drug discovery: A case study with melanocortin-4 receptor agonists | Full Text | References | PDF (130.5 KB)
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