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Xenobiotica
the fate of foreign compounds in biological systems
Volume 47, 2017 - Issue 10
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Animal Pharmacokinetics and Metabolism

Pharmacokinetic characterization of anhuienoside C and its deglycosylated metabolites in rats

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Pages 885-893 | Received 10 Aug 2016, Accepted 22 Sep 2016, Published online: 24 Oct 2016

References

  • Bae JK, Kim YJ, Chae HS, et al. (2016). Korean red ginseng extract enhances paclitaxel distribution to mammary tumors and its oral bioavailability by P-glycoprotein inhibition. Xenobiotica 17:1–10
  • Balimane PV, Han YH, Chong S. (2006). Current industrial practices of assessing permeability and P-glycoprotein interaction. Aaps J 8:E1–13
  • Benet LZ. (2013). The role of BCS (biopharmaceutics classification system) and BDDCS (biopharmaceutics drug disposition classification system) in drug development. J Pharm Sci 102:34–42
  • Chen X, Murawski A, Patel K, et al. (2008). A novel design of artificial membrane for improving the PAMPA model. Pharm Res 25:1511–20
  • Cheng S, Du Y, Bing F, Zhang G. (2008). Synthesis of flaccidoside II, a bidesmosidic triterpene saponin isolated from Chinese folk medicine Di Wu. Carbohydr Res 343:462–9
  • Huang X, Cheng S, Du Y, Bing F. (2009). Synthesis of oleanolic acid saponins mimicking components of Chinese folk medicine Di Wu. Carbohydr Res 344:1153–8
  • Huang XJ, Tang JQ, Li MM, et al. (2014). Triterpenoid saponins from the rhizomes of Anemone flaccida and their inhibitory activities on LPS-induced NO production in macrophage RAW264.7 cells. J Asian Nat Prod Res 16:910–21
  • Kikuchi R, de Morais SM, Kalvass JC. (2013). In vitro P-glycoprotein efflux ratio can predict the in vivo brain penetration regardless of biopharmaceutics drug disposition classification system class. Drug Metab Dispos 41:2012–17
  • Li M, de Graaf IA, Siissalo S, et al. (2016). The consequence of drug-drug Interactions influencing the interplay between P-glycoprotein and cytochrome P450 3a: an ex vivo study with rat precision-cut intestinal slices. Drug Metab Dispos 44:683–91
  • Liu H, Sun H, Wu Z, et al. (2014). P-glycoprotein (P-gp)-mediated efflux limits intestinal absorption of the Hsp90 inhibitor SNX-2112 in rats. Xenobiotica 44:763–8
  • Liu Q, Zhu XZ, Feng RB, et al. (2015). Crude triterpenoid saponins from Anemone flaccida (Di Wu) exert anti-arthritic effects on type II collagen-induced arthritis in rats. Chin Med 10:20
  • Lu D, Dong D, Liu Z, et al. (2015). Metabolism elucidation of BJ-B11 (a heat shock protein 90 inhibitor) by human liver microsomes: identification of main contributing enzymes. Expert Opin Drug Metab Toxicol 11:1029–40
  • Lu D, Ma Z, Zhang T, et al. (2016). Metabolism of the anthelmintic drug niclosamide by cytochrome P450 enzymes and UDP-glucuronosyltransferases: metabolite elucidation and main contributions from CYP1A2 and UGT1A1. Xenobiotica 46:1–13
  • Martignoni M, Groothuis G, de Kanter R. (2006). Comparison of mouse and rat cytochrome P450-mediated metabolism in liver and intestine. Drug Metab Dispos 34:1047–54
  • Nakamura M, Osakai T. (2016). Evaluation of the artificial membrane permeability of drugs by digital simulation. Eur J Pharm Sci 91:154–61
  • Palm K, Luthman K, Ros J, et al. (1999). Effect of molecular charge on intestinal epithelial drug transport: pH-dependent transport of cationic drugs. J Pharmacol Exp Ther 291:435–43
  • Polli JW, Jarrett JL, Studenberg SD, et al. (1999). Role of P-glycoprotein on the CNS disposition of amprenavir (141W94), an HIV protease inhibitor. Pharm Res 16:1206–12
  • Sugiyama D, Nishimura K, Tamaki K, et al. (2010). Impact of smoking as a risk factor for developing rheumatoid arthritis: a meta-analysis of observational studies. Ann Rheum Dis 69:70–81
  • Thiel-Demby VE, Humphreys JE, St John Williams LA, et al. (2009). Biopharmaceutics classification system: validation and learnings of an in vitro permeability assay. Mol Pharm 6:11–18
  • Trdan Lušin T, Mrhar A, Stieger B, et al. (2012). Influence of hepatic and intestinal efflux transporters and their genetic variants on the pharmacokinetics and pharmacodynamics of raloxifene in osteoporosis treatment. Transl Res 160:298–308
  • Varma MV, Sateesh K, Panchagnula R. (2005). Functional role of P-glycoprotein in limiting intestinal absorption of drugs: contribution of passive permeability to P-glycoprotein mediated efflux transport. Mol Pharm 2:12–21
  • Volpe DA. (2008). Variability in Caco-2 and MDCK cell-based intestinal permeability assays. J Pharm Sci 97:712–25
  • Ye WC, Zhang QW, Zhao SX, Che CT. (2001). Four new oleanane saponins from Anemone anhuiensis. Chem Pharm Bull (Tokyo) 49:632–4
  • Zhao H, Liu H, Ma Z, et al. (2015). Metabolite profiling of anhuienoside C by rat intestinal bacteria using the LC-MS metabolomic approach. Xenobiotica 45:189–96

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