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Xenobiotica
the fate of foreign compounds in biological systems
Volume 49, 2019 - Issue 4
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Animal Pharmacokinetics and Metabolism

Evaluation of interconversion pharmacokinetics of 16α-hydroxycleroda-3,13(14)Z-dien-15,16-olide – a novel HMG-CoA reductase inhibitor and its acid metabolite using multi-compartmental pharmacokinetic model in mice

Tulsankar Sachin LaxmanPharmacokinetics & Metabolism Division, CSIR-Central Drug Research Institute, Lucknow, India; ;Academy of Scientific and Innovative Research (AcSIR), New Delhi, India; View further author information
,
Santosh Kumar PuttervuPharmacokinetics & Metabolism Division, CSIR-Central Drug Research Institute, Lucknow, India; ;Academy of Scientific and Innovative Research (AcSIR), New Delhi, India; View further author information
,
Anjali MishraPharmacokinetics & Metabolism Division, CSIR-Central Drug Research Institute, Lucknow, India; View further author information
,
Sarvesh VermaPharmacokinetics & Metabolism Division, CSIR-Central Drug Research Institute, Lucknow, India; View further author information
,
S. P. SinghMedicinal & Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow, India; View further author information
,
K. V. SashidharaMedicinal & Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow, India; View further author information
,
C. M. MarandiDepartment of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Rae Bareli, IndiaView further author information
,
Shivani SaxenaDepartment of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Rae Bareli, IndiaView further author information
,
Manoj K. YadavMedicinal & Process Chemistry Division, CSIR-Central Drug Research Institute, Lucknow, India; View further author information
&
Rabi S. BhattaPharmacokinetics & Metabolism Division, CSIR-Central Drug Research Institute, Lucknow, India; ;Department of Pharmaceutics, National Institute of Pharmaceutical Education and Research (NIPER), Rae Bareli, IndiaCorrespondence[email protected] [email protected]
View further author information
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Pages 474-483 | Received 01 Feb 2018, Accepted 09 Mar 2018, Published online: 11 Apr 2018

References

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  • Tulsankar SL, SKP, Sarvesh Verma A, Sankar Bhatta R. 2018. In vitro and in vivo metabolite identification of 16α-hydroxycleroda-3,13(14)Z-dien-15,16-olide in mice and rat. Unpublished laboratory observations.

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