Interactions between cadmium and zinc on gene expression pattern of differentiation markers in MC3T3-E1 cell line

References

• Alcantara EH, Lomeda RA, Feldmann J, Nixon GF, Beattie JH, Kwun IS. 2011. Zinc deprivation inhibits extracellular matrix calcification through decreased synthesis of matrix proteins in osteoblasts. Mol Nutr Food Res. 55(10):1552–1560.
   PubMed Web of Science ®Google Scholar
• Alfven T, Elinder CG, Carlsson MD, Grubb A, Hellström L, Persson B, Pettersson C, Spång G, Schütz A, Järup L. 2000. Low-level cadmium exposure and osteoporosis. J Bone Miner Res. 15(8):1579–1586.
   PubMed Web of Science ®Google Scholar
• Baht G, Hunter G, Goldberg H. 2008. Bone sialoprotein-collagen interaction promotes hydroxyapatite nucleation. Matrix Biol. 27(7):600–608.
   PubMed Web of Science ®Google Scholar
• Banni M, Chouchene L, Saïd K, Kerkeni A, Messaoudi I. 2011. Mechanisms underlying the protective effect of zinc and selenium against cadmium-induced oxidative stress in zebrafish Danio rerio. Biometals. 24(6):981–992.
   PubMed Web of Science ®Google Scholar
• Bertin G, Averbeck D. 2006. Cadmium: cellular effects, modifications of biomolecules, modulation of DNA repair and genotoxic consequences (a review). Biochimie. 88(11):1549–1559.
   PubMed Web of Science ®Google Scholar
• Bianco P, Riminucci M, Bonucci E, Termine J, Robey PG. 1993. Bone sialoprotein (BSP) secretion and osteoblast differentiation: relationship to bromodeoxyuridine incorporation, alkaline phosphatase, and matrix deposition. J Histochem Cytochem. 41(2):183–191.
   PubMed Web of Science ®Google Scholar
• Bodo P, Balloni S, Lumare E, Bacci M, Calvitti M, Dell’Omo M, Murgia N, Marinucci L. 2010. Effects of sub-toxic cadmium concentrations on bone gene expression program: Results of an in vitro study. Toxicol in Vitro. 24(6):1670–1680.
   PubMed Web of Science ®Google Scholar
• Boughammoura S, Ben Mimouna S, Chemek M, Ostertag A, Cohen-Solal M, Messaoudi I. 2020. Disruption of bone zinc metabolism during postnatal development of rats after early life exposure to cadmium. Int J Mol Sci. 121(4):1218.
   Web of Science ®Google Scholar
• Boughammoura S, Chemek M, Ben Mimouna S, Banni M, Messaoudi I. 2017. Involvement of Zn depletion in Cd-induced toxicity on prenatal bone formation in rat. Biol Trace Elem Res. 180(1):70–80.
   PubMed Web of Science ®Google Scholar
• Brama M, Politi L, Santini P, Migliaccio S, Scandurraet R. 2012. Cadmium-induced apoptosis and necrosis in human osteoblasts: role of caspases and mitogen-activated protein kinases pathways. J Endocr Invest. 35:198–208.
   PubMed Web of Science ®Google Scholar
• Bremner I, Beattie JH. 1995. Copper and zinc metabolism in health and disease: speciation and interactions. Proc Nutr Soc. 54(2):489–499.
   PubMed Web of Science ®Google Scholar
• Brzoska MM, Majewska K, Moniuszko-Jakoniuk J. 2005. Mechanical properties of femoral diaphysis and femoral neck of female rats chronically exposed to various levels of cadmium. Calcif Tissue Int. 76(4):287–298.
   PubMed Web of Science ®Google Scholar
• Brzóska MM, Moniuszko-Jakoniuk J. 2001. Interactions between cadmium and zinc in the organism. Food Chem Toxicol. 39(10):967–980.
   PubMed Web of Science ®Google Scholar
• Brzoska MM, Moniuszko-Jakoniuk J, Jurczuk M, Gałazyn-Sidorczuk M, Rogalska J. 2000. Effect of short-term ethanol administration on cadmium retention and bioelement metabolism in rats continuously exposed to cadmium. Alcohol Alcohol. 5:439–445.
   Web of Science ®Google Scholar
• Brzoska MM, Moniuszko-Jakoniuk J, Jurczuk M, Gałażyn-Sidorczuk M, Rogalska J. 2001. The effect of zinc supply on cadmium-induced changes in the tibia of rats. Food Chem Toxicol. 39(7):729–734.
   PubMed Web of Science ®Google Scholar
• Brzóska MM, Rogalska J, Galażyn-Sidorczuk M, Jurczuk M, Roszczenko A, Kulikowska-Karpińska E, Moniuszko-Jakoniuk J. 2007. Effect of zinc supplementation on bone metabolism in male rats chronically exposed to cadmium. Toxicology. 237(1–3):89–103.
   PubMed Web of Science ®Google Scholar
• Chemek M, Ben Mimouna S, Boughammoura S, Delbès G, Messaoudi I. 2016. Protective role of zinc against the toxicity induced by exposure to cadmium during gestation and lactation on testis development. Reprod Toxicol. 63:151–160.
   PubMed Web of Science ®Google Scholar
• Chemek M, Boughammoura S, Ben Mimouna S, Chouchene L, Banni M, Messaoudi I. 2015. Changes of the mRNA expression pattern of Zn transporters: a probable mechanism for cadmium retention and zinc redistribution in the suckling rat tissues. Biol Trace Elem Res. 165(2):173–182.
   PubMed Web of Science ®Google Scholar
• Chen X, Zhu G, Gu S, Jin T, Shao C. 2009. Effect of cadmium on osteoblasts and osteoclasts in vitro. Environ Toxicol Pharmacol. 28(2):232–236.
   PubMed Web of Science ®Google Scholar
• Chen X, Zhu G, Jin T, Zhou Z, Gu S, Qiu J, Xiao H. 2012. Cadmium stimulates the osteoclastic differentiation of RAW264.7 cells in presence of osteoblasts. Biol Trace Elem Res. 146(3):349–353.
   PubMed Web of Science ®Google Scholar
• Cho YE, Kwun IS. 2018. Zinc upregulates bone-specific transcription factor Runx2 expression via BMP-2 signaling and Smad-1 phosphorylation in osteoblasts. J Nutr Health. 51(1):23.
   Google Scholar
• Chouchene L, Banni M, Kerkeni A, Saïd K, Messaoudi I. 2011. Cadmium-induced ovarian pathophysiology is mediated by change in gene expression pattern of zinc transporters in zebrafish (Daniorerio). Chem Biol Interact. 193(2):172–179.
   PubMed Web of Science ®Google Scholar
• Comelekoglu U, Yalin S, Bagis S, Ogenler O, Sahin NO, Yildiz A, Coskun B, Hatungil R, Turac A. 2007. Low-exposure cadmium is more toxic on osteoporotic rat femoral bone: mechanical, biochemical, and histopathological evaluation. Ecotoxicol Environ Saf. 66(2):267–271.
   PubMed Web of Science ®Google Scholar
• El Heni J, Hammouda F, Allègue N, Baati T, Messaoudi I, Kerkeni A. 2010. Cadmium retention increase: a probable key mechanism of the protective effect of zinc on cadmium-induced toxicity in the kidney. Toxicol Lett. 196:104–109.
   PubMed Web of Science ®Google Scholar
• Fernley HN, Walker PG. 1970. Inhibition of alkaline phosphatase by L-phenylalanine. Biochem J. 116(3):543–544.
   PubMed Web of Science ®Google Scholar
• Galicka A, Brzóska MM, Sredzińska K, Gindzienski A. 2004. Effect of cadmium on collagen content and solubility in rat bone. Acta Biochim Pol. 51(3):825–829.
   PubMed Web of Science ®Google Scholar
• Hamamura K, Yokota H. 2007. Stress to endoplasmic reticulum of mouse osteoblasts induces apoptosis and transcriptional activation for bone remodeling. FEBS Lett. 581(9):1769–1774.
   PubMed Web of Science ®Google Scholar
• Hashizume M, Yamaguchi M. 1994. Effect of beta-alanyl-L-histidina to zinc on differentiation of osteoblastic MC3T3-E1 cells: increases in alkaline phosphatase activity and protein concentration. Mol Cell Biochem. 131(1):19–24.
   PubMed Web of Science ®Google Scholar
• Hie M, Iitsuka N, Otsuka T, Nakanishi A, Tsukamoto I. 2011. Zinc deficiency decreases osteoblasts and osteoclasts associated with the reduced expression of Runx2 and RANK. Bone. 49(6):1152–1159.
   PubMed Web of Science ®Google Scholar
• Johri M, Morales RE, Hoch JS, Samayoa BE, Sommen C, Grazioso CF, Boivin JF, Barrios Matta IJ, Baide Diaz EL, Arathoon EG. 2010. A cross-sectional study of risk factors for HIV among pregnant women in Guatemala City, Guatemala: lessons for prevention. Int J STD Aids. 21(12):789–796.
   PubMed Web of Science ®Google Scholar
• Kaji T, Takata M, Hoshino T, Miyahara T, Kozuka H, Kurashige Y, Koizumi F. 1988. Role of zinc in protection against cadmium-induced toxicity in formation of embryonic chick bone in tissue culture. Toxicol Lett. 44(1–2):219–227.
   PubMed Web of Science ®Google Scholar
• Kazantzis G. 2004. Cadmium, osteoporosis and calcium metabolism. Biometals. 17(5):493–498.
   PubMed Web of Science ®Google Scholar
• Keogh MB, O' Brien FJ, Daly JS. 2010. A novel collagen scaffold supports human osteogenesis-applications for bone tissue engineering. Cell Tissue Res. 340(1):169–177.
   PubMed Web of Science ®Google Scholar
• Kim J, Sharma RP. 2006. Cadmium-induced apoptosis in murine macrophages is antagonized by antioxidants and caspase inhibitors. J Toxicol Environ Health A. 69(12):1181–1201.
   PubMed Web of Science ®Google Scholar
• Kwun IS, Cho YE, Lomeda RAR, Shin HI, Choi JY, Kang YH, Beattie JH. 2010. Zinc deficiency suppresses matrix mineralization and retards osteogenesis transiently with catch-up possibly through Runx 2 modulation. Bone. 46(3):732–741.
   PubMed Web of Science ®Google Scholar
• Lansdown AB, Sampson B, Rowe A. 2001. Experimental observations in the rat on the influence of cadmium on skin wound repair. Int J Exp Pathol. 82(1):35–41.
   PubMed Web of Science ®Google Scholar
• Lévesque M, Martineau C, Jumarie C, Moreau R. 2008. Characterization of cadmium uptake and cytotoxicity in human osteoblast-like MG-63cells. Toxicol Appl Pharmacol. 231(3):308–317.
   PubMed Web of Science ®Google Scholar
• Livak KJ, Schmittgen TD. 2001. Analysis of relative gene expression data using real-time quantitative PCR and the 2 − ΔΔCt method. Methods. 25(4):402–408.
   PubMed Web of Science ®Google Scholar
• Mazorra MT, Rubio JA, Blasco J. 2002. Acid and alkaline phosphatase activities in the clam Scrobicularia plana: kinetic characteristics and effects of heavy metals. Comp Biochem Physiol B Biochem Mol Biol. 131(2):241–249.
   PubMed Web of Science ®Google Scholar
• Messaoudi I, Banni M, Saïd L, Saïd K, Kerkeni A. 2010. Evaluation of involvement of testicular metallothionein gene expression in the protective effect of zinc against cadmium-induced testicular pathophysiology in rat. Reprod Toxicol. 29(3):339–345.
   PubMed Web of Science ®Google Scholar
• Miyahara T, Oh-e Y, Takaine E, Kozuka H. 1983. Interaction between cadmium and zinc, copper, or lead in relation to the collagen and mineral content of embryonic chick bone in tissue culture. Toxicol Appl Pharmacol. 67(1):41–48.
   PubMed Web of Science ®Google Scholar
• Nakano Y, Addison WN, Kaartinen MT. 2007. ATP-mediated mineralization of MC3T3-E1 osteoblast cultures. Bone. 41(4):549–561.
   PubMed Web of Science ®Google Scholar
• Nishi Y. 1996. Zinc and growth. J Am Coll Nutr. 15(4):340–344.
   PubMed Web of Science ®Google Scholar
• Ogoshi K, Iwami K, Moriyama T, Nanzai Y. 1984. The changes in mechanical properties of rat bones under the low dose level of cadmium. (II) The torsional strength. Jpn J Hyg. 39(5):848–854.
   PubMedGoogle Scholar
• Ogoshi K, Nanzai Y, Moriyama T. 1992. Decrease in bone strength of cadmium-treated young and old rats. Arch Toxicol. 66(5):315–320.
   PubMed Web of Science ®Google Scholar
• Okano T. 1996. Effects of essential trace elements on bone turnover in relation to the osteoporosis. Nippon Rinsho. 54:148–154.
   PubMedGoogle Scholar
• Oner G, Bhaumick B, Bala RM. 1984. Effect of zinc deficiency on serum somatomedin levels and skeletal growth in young rats. Endocrinology. 114(5):1860–1863.
   PubMed Web of Science ®Google Scholar
• Ou L, Wang H, Wu Z, Wang P, Yang L, Li X, Sun K, Zhu X, Zhang R. 2021. Effects of cadmium on osteoblast cell line: exportin 1 accumulation, p-JNK activation, DNA damage and cell apoptosis. Ecotoxicol Environ Saf. 208:111668–111668.
   PubMed Web of Science ®Google Scholar
• Park KH, Choi Y, Yoon DS, Lee KM, Kim D, Lee JW. 2018. Zinc promotes osteoblast differentiation in human mesenchymal stem cells via activation of the cAMP-PKA-CREB signaling pathway. Stem Cells Dev. 27(16):1125–1135.
   PubMed Web of Science ®Google Scholar
• Regunathan A, Glesne DA, Wilson AK, Song J, Nicolae D, Flores T, Bhattacharyya MH. 2003. Microarray analysis of changes in bone cell gene expression early after cadmium gavage in mice. T Toxicol Appl Pharmacol. 191(3):272–293.
   PubMed Web of Science ®Google Scholar
• Romare A, Lundholm CE. 1999. Cadmium-induced calcium release and prostaglandin E2 production in neonatal mouse calvaria are dependent on cox-2 induction and protein kinase C activation. Arch Toxicol. 73(4–5):223–228.
   PubMed Web of Science ®Google Scholar
• Rükgauer M, Neugebauer RJ, Plecko T. 2001. The relation between selenium, zinc and copper concentration and the trace element dependent antioxidative status. J Trace Elem Med Biol. 15(2–3):73–78.
   PubMed Web of Science ®Google Scholar
• Seo HJ, Cho YE, Kim T, Shin HI, Kwun IS. 2010. Zinc may increase bone formation through stimulating cell proliferation, alkaline phosphatase activity and collagen synthesis in osteoblastic MC3T3-E1 cells. Nutr Res Pract. 4(5):356–361.
   PubMed Web of Science ®Google Scholar
• Smith SS, Reyes JR, Arbon KS, Harvey WA, Hunt LM, Heggland SJ. 2009. Cadmium-induced decrease in RUNX2 mRNA expression and recovery by the antioxidant N-acetylcysteine (NAC) in the human osteoblast-like cell line, Saos-2. Toxicol in Vitro. 23(1):60–66.
   PubMed Web of Science ®Google Scholar
• Stein GS, Lian JB. 1993. Molecular mechanisms mediating developmental and hormone-regulated expression of genes in osteoblasts: an integrated relationship of cell growth and differentiation. In: Noda M, editor. Cellular and molecular biology of bone. Tokyo: Academic Press; p. 47–95.
   Google Scholar
• Sudo H, Kodama HA, Amagai Y, Yamamoto S, Kasai S. l983. In vitro differentiation and calcification in a new clonal osteogenic cell line derived from newborn mouse calvaria. J Cell Biol. 96(1):191–198.
   PubMed Web of Science ®Google Scholar
• Sun JY, Wang JF, Zi NT, Jing MY, Weng XY. 2011. Effects of zinc supplementation and deficiency on bone metabolism and related gene expression in rat. Biol Trace Elem Res. 143(1):394–402.
   PubMed Web of Science ®Google Scholar
• Suzuki Y, Morita I, Yamane Y, Murota S. 1989. Preventive effects of zinc on cadmium-induced inhibition of alkaline phosphatase activity and mineralization activity in osteoblast-like cells, MC3T3-E1. J Pharmacobiodyn. 12(2):94–99.
   PubMedGoogle Scholar
• Tanaka M, Yanagi M, Shirota K, Une Y, Nomura Y, Masaoka T, Akahori F. 1995. Effect of cadmium in the zinc deficient rat. Vet Hum Toxicol. 37(3):203–208.
   PubMedGoogle Scholar
• Waalkes MP. 1986. Effect of dietary zinc deficiency on the accumulation of cadmium and metallothionein in selected tissues of the rat. J Toxicol Environ Health. 18(2):301–313.
   PubMed Web of Science ®Google Scholar
• Wallwork JC, Sandstead HH. 1990. Zinc in nutrition and bone development. Simmons DJ, editor. New York (NY): Oxford University Press.
   Google Scholar
• Yamaguchi M. 1998. Role of zinc in bone formation and bone resorption. J Trace Elem Exp Med. 11(2-3):119–135.
   Google Scholar
• Yao KL, Todescan R Jr, Sodek J. 1994. Temporal changes in matrix protein synthesis and mRNA expression during mineralized tissue formation by adult rat bone marrow cells in culture. J Bone Miner Res. 9(2):231–240.
   PubMed Web of Science ®Google Scholar
• Zhang D, Liu J, Gao J, Shahzad M, Han Z, Wang Z, Li J, Sjölinder H. 2014. Zinc supplementation protects against cadmium accumulation and cytotoxicity in Madin-Darby Bovine kidney cells. PLoS One. 9(8):e103427.
   PubMed Web of Science ®Google Scholar
• Zhukalin M, Blanksma MK, Silva TD, Suyehira SW, Harvey WA, Heggland SJ, Craig PR. 2007. Characterization and in vitro cytotoxicity testing of ethanolamine-derived cadmium chelating agents. Biometals. 20(1):61–72.
   PubMed Web of Science ®Google Scholar