References
- ABE, T., FLANAGAN, A. M. and CHAMBERS, T. J., 1990, Comparative studies of actions of bisphosphonates on bone resorption in vitro. Journal of Bone and Mineral Research, 5 (suppl. 2), S86.
- BARBlER, A., ROQUE, C., MURAKAMI, H., NYS, M., TIRODE, F., MARTEL, C., CHABBERT, M., CAHARD, D., REMANDET, B. and LACITERETZ, F., 1995, Bone localization of '4 C-tiludronate in rats. Bone, 16 (suppl.), 228S.
- FLEISC H., 1991, Bisphosphonates : pharmacology and use in the treatment of tumour-induced hypercalcaemic and metastatic bone disease. Drugs, 42,919–944.
- GRYNPAS, M. D., RENLUND, R. and PRITZKER, K. P. H., 1991, The effect of short term pamidronate (APD) administration on canine bone mineral and matrix. Journal of Bone and Mineral Research, 6 (Suppl.), S98.
- HALL, D. G. and STOICA, G., 1994, Effect of the bisphosphonate risedronate on bone metastases in a rat mammary adenocarcinoma model system. Journal of Bone and Mineral Research, 9,221–230.
- HIRAGA, T., TANAKA, S., YAMAMOTO, M., NAKAJIMA, T. and OZAWA, H., 1996, Inhibitory effects of bisphosphonate (YM175) on bone resorption induced by a metastatic bone tumour. Bone, 18,1–7.
- KAWAMUKI, K., ABE, T., KUDO, M., OUCHI, N., MOTO1E, H., Usui, T., IsomuRA, Y., TAKEUCHI, M. and KAWASHEVIA, H., 1990, Effect of YM175 on bone positively correlates with its concentration in bone. Journal of Bone and Mineral Research, 5 (suppl. 2), S245.
- KUDO, M., ABE, T., KAWAMUKI, K., YAMAOKA, E., IsomuRA, Y., TAICEUCHI, M. and KAWASHIMA, H., 1990, Effect of YM175 on experimental hypercalcemia and tumour-induced osteolysis in rats. Journal of Bone and Mineral Research, 5 (suppl. 2), S166.
- MUNDY, G. R. and MARTIN, T. J., 1993, Pathophysiology of skeletal complications of cancer. In Physiology and Pharmacology of Bone, edited by G. R. Mundy and T. J. Martin (Berlin: Springer), pp. 641–671.
- NAGAO, Y., ISHITOBI, Y., FUKUSHIMA, S., KINOSHITA, H., KAWASHIMA, H. and KUMEGAWA, M., 1990, YM175 inhibits osteoclast differentiation and bone resorbing action of mature osteoclasts . Journal of Bone and Mineral Research, 5 (suppl. 2), S159.
- NAKAI, M., MUNDY, G. R., WILLIAMS, P. J., BOYCE, B. and YONEDA, T., 1992, A synthetic antagonist to laminin inhibits the formation of osteolytic metastases by human melanoma cells in nude mice. Cancer Research, 52,5395–5399.
- NAKAIVIURA, E., IMASAKI, H., Usui, T., WATANABE, T. and HIGUCHI, S., 1994, Metabolic fate of YM175: distribution and excretion of radioactivity after intravenous administration of '4C-YM175 to rats. Xenobiotic Metabolism and Disposition, 9,835–847.
- SASAKI, A., BOYCE, B. F., STORY, B., WRIGHT, K. R., CHAPMAN, M., BOYCE, R., MUNDY, G. R. and YONEDA, T., 1995, Bisphosphonate risedronate reduces metastatic human breast cancer burden in bone in nude mice. Cancer Research, 55,3551–3557.
- SATO, M., GRASSER, W., ENDO, N., AKINS, R., SIMMONS, H., THOMPSON, D. D., GOLUB, E. and RODAN, G. A., 1991, Bisphosphonate action: alendronate localization in rat bone and effects on osteoclast ultrastructure. Journal of Clinical Investigation, 88,2095–2105.
- TAKAHASHI, K., FUKUSHIMA, S., KoKuso, S., TERAMURA, K. and TANAKA, T., 1994, Effect of YM175 on hypercalcemia induced by human squamous cell carcinoma of oral cavity. Clinical Report, 28, 2905–2919.
- TAKEUCHI, M., SAKAMOTO, S., YOSHIDA, M., ABE, T. and IsomuRA, Y., 1993, Studies of novel bone re-sorption inhibitors. I. Synthesis and pharmacological activity of aminomethylenebisphosphonate derivatives. Chemical and Pharmaceutical Bulletin, 41,688–693.
- TANAKA, S., HIRAGA, T., O ZAWA, Y., TERAMURA, K., MOTOIE, H., TANAKA, T., YAMAMOTO, M. and O ZAWA, H., 1995, YM175 inhibits tumour-induced osteolysis in nude mice with bone metastases. Journal of Bone MM. Research., 10 (suppl. 1), P262.
- Uso, T., WATANABE, T. and HIGUCHI, S., 1995, Pharmacokinetics of YM175, a new bisphosphonate, in rats and dogs. Drug Metabolism and Disposition, 23,1214–1219.
- Uso, T., WATANABE, T. and HIGUCHI, S., 1996. Effect of dose, sex and age on the drug disposition of incadronate, a new bisphosphonate, in rat bone. Pharmacology and Toxicology, 79,254–258.