Sexual Function of Male Survivors of Hematological Malignancy Treated by Autologous Hematopoietic Stem Cell Transplantation: A Multicenter Controlled Observational Study

References

• Aksoy, S., Harputluoglu, H., Kilickap, S., Dincer, M., Dizdar, O., Akdogan, B., … Celik, I. (2008). Erectile dysfunction in successfully treated lymphoma patients. Supportive Care in Cancer, 16(3), 291–297. doi:10.1007/s00520-007-0307-y
   PubMed Web of Science ®Google Scholar
• Beckjord, E. B., Arora, N. K., Bellizzi, K., Hamilton, A. S., & Rowland, J. H. (2011, September). Sexual well-being among survivors of non-Hodgkin lymphoma. In Oncology Nursing Forum (Vol. 38). doi:10.1188/11.ONF.E351-E359
   Google Scholar
• Behringer, K., Müller, H., Görgen, H., Flechtner, H. H., Brillant, C., Halbsguth, T. V., … Borchmann, P. (2013). Sexual quality of life in Hodgkin Lymphoma: A longitudinal analysis by the German Hodgkin Study Group. British journal of cancer, 108(1), 49–57. doi:10.1038/bjc.2012.550
   PubMed Web of Science ®Google Scholar
• Bersvendsen, H. S., Haugnes, H. S., Dahl, A. A., Fagerli, U. M., Fluge, Ø., Holte, H., … Kiserud, C. E. (2020). Sexual function in long-term male lymphoma survivors after high-dose therapy with autologous stem-cell transplantation. Bone marrow transplantation, 55(5), 891–905. doi:10.1038/s41409-019-0745-4
   PubMed Web of Science ®Google Scholar
• Bersvendsen, H. S., Haugnes, H. S., Fagerli, U., Fluge, Ø., Holte, H., Smeland, K. B., & Kiserud, C. E. (2019). Reduced sexual function in long‐term male lymphoma survivors after high dose therapy with autologous stem cell transplantation. Hematological Oncology, 37, 544–545. doi:10.1002/hon.231_2631
   Google Scholar
• Bevans, M., El-Jawahri, A., Tierney, D. K., Wiener, L., Wood, W. A., Hoodin, F., … Syrjala, K. L. (2017). National Institutes of Health hematopoietic cell transplantation late effects initiative: The patient-centered outcomes working group report. Biology of Blood and Marrow Transplantation, 23(4), 538–551. doi:10.1016/j.bbmt.2016.09.011
   PubMed Web of Science ®Google Scholar
• Boyne, D. J., Mickle, A. T., Brenner, D. R., Friedenreich, C. M., Cheung, W. Y., Tang, K. L., … Rabi, D. M. (2018). Long‐term risk of cardiovascular mortality in lymphoma survivors: A systematic review and meta‐analysis. Cancer medicine, 7(9), 4801–4813. doi:10.1002/cam4.1572
   PubMed Web of Science ®Google Scholar
• Carreras, E., Dufour, C., Mohty, M., & Kröger, N. (2019). The EBMT handbook: Hematopoietic stem cell transplantation and cellular therapies (7th ed.). Cham: Springer. doi:10.1007/978-3-030-02278-5
   Google Scholar
• Carroll, J. B. (1993). Human cognitive abilities: A survey of factor-analytic studies (No. 1). Cambridge, England: Cambridge University Press. doi:10.1017/CBO9780511571312
   Google Scholar
• Dahan, J. F., & Auerbach, C. F. (2006). A qualitative study of the trauma and posttraumatic growth of multiple myeloma patients treated with peripheral blood stem cell transplant. Palliative & Supportive Care, 4(4), 365–387. doi:10.1017/s1478951506060470
   PubMedGoogle Scholar
• DeRogatis, L. R. (2008). Assessment of sexual function/dysfunction via patient reported outcomes. International Journal of Impotence Research, 20(1), 35–44. doi:10.1038/sj.ijir.3901591
   PubMed Web of Science ®Google Scholar
• Dominguez, L. J., & Barbagallo, M. (2016). Ageing and sexuality. European Geriatric Medicine, 7(6), 512–518. doi:10.1016/j.eurger.2016.05.013
   Web of Science ®Google Scholar
• Eeltink, C. M., Lissenberg-Witte, B. I., Incrocci, L., Braamse, A. M., Visser, O., Zijlstra, J., … Zweegman, S. (2020). Self-reported sexual function in sexually active male hodgkin lymphoma survivors. Sexual medicine, 8(3), 428–435. doi:10.1016/j.esxm.2020.04.005
   PubMed Web of Science ®Google Scholar
• Gan, G. G., Ng, D. L. C., & Leong, Y. C. (2022). Erectile dysfunction in male lymphoma survivors in a Southeast Asian country. Singapore medical journal, 63(7), 376–380. doi:10.11622/smedj.2021003
   PubMed Web of Science ®Google Scholar
• Georges, G. E., Bar, M., Onstad, L., Jean, C. Y., Shadman, M., Flowers, M. E., … Holmberg, L. A. (2020). Survivorship after autologous hematopoietic cell transplantation for lymphoma and multiple myeloma: Late effects and quality of life. Biology of Blood and Marrow Transplantation, 26(2), 407–412. doi:10.1016/j.bbmt.2019.10.002
   PubMed Web of Science ®Google Scholar
• Hatzimouratidis, K., Amar, E., Eardley, I., Giuliano, F., Hatzichristou, D., Montorsi, F., … Wespes, E. (2010). Guidelines on male sexual dysfunction: Erectile dysfunction and premature ejaculation. European Urology, 57(5), 804–814. doi:10.1016/j.eururo.2010.02.020
   PubMed Web of Science ®Google Scholar
• Hatzimouratidis, K., Tsimtsiou, Z., Karantana, A., Chatzichristou, D. (2001). Cultural and linguistic evaluation of the International Index of Erectile Function (IIEF) in the Greek language. Elliniki Ourologia, 13: 313–321.
   Google Scholar
• Henkelman, M., Toivonen, K. I., Tay, J., Beattie, S., & Walker, L. M. (2022, March 1). Patient reported disease-specific concerns relating to sexuality in multiple myeloma. Preprint from Research Square. doi:10.21203/rs.3.rs-1293944/v1
   Google Scholar
• Hoffman, K. E., McCarthy, E. P., Recklitis, C. J., & Ng, A. K. (2009). Psychological distress in long-term survivors of adult-onset cancer: Results from a national survey. Archives of internal medicine, 169(14), 1274–1281. doi:10.1001/archinternmed.2009.179
   PubMed Web of Science ®Google Scholar
• Humphreys, C. T., Tallman, B., Altmaier, E. M., & Barnette, V. (2007). Sexual functioning in patients undergoing bone marrow transplantation: A longitudinal study. Bone marrow transplantation, 39(8), 491–496. doi:10.1038/sj.bmt.1705613
   PubMed Web of Science ®Google Scholar
• Kenyon, M., & Babic, A. (2018). The European blood and marrow transplantation textbook for nurses: Under the auspices of EBMT. Cham: Springer. doi:10.1007/978-3-319-50026-3
   Google Scholar
• Kim, I. R., Kim, S. H., Ok, O. N., Kim, S. H., Lee, S., Choi, E., … Lee, M. H. (2017). Sexual problems in male vs. female non-Hodgkin lymphoma survivors: Prevalence, correlates, and associations with health-related quality of life. Annals of hematology, 96(5), 739–747. doi:10.1007/s00277-017-2940-y
   PubMed Web of Science ®Google Scholar
• Kiserud, C. E., Schover, L. R., Dahl, A. A., Fosså, A., Bjøro, T., Loge, J. H., … Fosså, S. D. (2009). Do male lymphoma survivors have impaired sexual function? Journal of Clinical Oncology, 27(35), 6019–6026. doi:10.1200/JCO.2009.23.2280
   PubMed Web of Science ®Google Scholar
• Langer, S. L., Rudd, M. E., & Syrjala, K. L. (2007). Protective buffering and emotional desynchrony among spousal caregivers of cancer patients. Health Psychology, 26(5), 635. doi:10.1037/0278-6133.26.5.635
   PubMed Web of Science ®Google Scholar
• Lee, S. J., Schover, L. R., Partridge, A. H., Patrizio, P., Wallace, W. H., Hagerty, K., … Oktay, K. (2006). American Society of Clinical Oncology recommendations on fertility preservation in cancer patients. Journal of clinical oncology, 24(18), 2917–2931. doi:10.1200/JCO.2006.06.5888
   PubMed Web of Science ®Google Scholar
• Lee, J. J. (2011, July). Sexual dysfunction after hematopoietic stem cell transplantation. In Oncology Nursing Forum (Vol. 38, p. 409). Oncology Nursing Society. doi:10.1188/11.ONF.409-412
   Google Scholar
• Miner, M., Parish, S. J., Billups, K. L., Paulos, M., Sigman, M., & Blaha, M. J. (2019). Erectile Dysfunction and Subclinical Cardiovascular Disease. Sexual medicine reviews, 7(3), 455–463. doi:10.1016/j.sxmr.2018.01.001
   PubMed Web of Science ®Google Scholar
• Mitchell, K. R., Mercer, C. H., Ploubidis, G. B., Jones, K. G., Datta, J., Field, N., … Wellings, K. (2013). Sexual function in Britain: Findings from the third National Survey of Sexual Attitudes and Lifestyles (Natsal-3). The Lancet, 382(9907), 1817–1829. doi:10.1016/S0140-6736(13)62366-1
   PubMed Web of Science ®Google Scholar
• Mosher, C. E., Redd, W. H., Rini, C. M., Burkhalter, J. E., & DuHamel, K. N. (2009). Physical, psychological, and social sequelae following hematopoietic stem cell transplantation: A review of the literature. Psycho‐Oncology: Journal of the Psychological, Social and Behavioral Dimensions of Cancer, 18(2), 113–127. doi:10.1002/pon.1399
   PubMed Web of Science ®Google Scholar
• Naik, A. D., Uy, N., Anaya, D. A., & Moye, J. (2015). The effects of age, education, and treatment on physical, sexual and body concern symptoms among multimorbid, colorectal cancer survivors. Journal of geriatric oncology, 6(4), 299–306. doi:10.1016/j.jgo.2015.04.001
   PubMed Web of Science ®Google Scholar
• Neijenhuijs, K. I., Holtmaat, K., Aaronson, N. K., Holzner, B., Terwee, C. B., Cuijpers, P., & Verdonck-de Leeuw, I. M. (2019). The International Index of Erectile Function (IIEF)—A systematic review of measurement properties. The Journal of Sexual Medicine, 16(7), 1078–1091. doi:10.1016/j.jsxm.2019.04.010
   PubMed Web of Science ®Google Scholar
• Niscola, P., Efficace, F., & Abruzzese, E. (2018). Sexual health in patients with hematological malignancies: A neglected issue. Supportive Care in Cancer, 26(6), 1699–1701. doi:10.1007/s00520-018-4124-2
   PubMed Web of Science ®Google Scholar
• Oken, M. M., Creech, R. H., Tormey, D. C., Horton, J., Davis, T. E., McFadden, E. T., & Carbone, P. P. (1982). Toxicity and response criteria of the Eastern Cooperative Oncology Group. American journal of clinical oncology, 5(6), 649–656. doi:10.1097/00000421-198212000-00014
   PubMed Web of Science ®Google Scholar
• Pulewka, K., Strauss, B., Hochhaus, A., & Hilgendorf, I. (2021). Clinical, social, and psycho-oncological needs of adolescents and young adults (AYA) versus older patients following hematopoietic stem cell transplantation. Journal of Cancer Research and Clinical Oncology, 147(4), 1239–1246. doi:10.1007/s00432-020-03419-z
   PubMed Web of Science ®Google Scholar
• Raheem, O. A., Su, J. J., Wilson, J. R., & Hsieh, T. C. (2017). The association of erectile dysfunction and cardiovascular disease: A systematic critical review. American journal of men’s health, 11(3), 552–563. doi:10.1177/1557988316630305
   PubMed Web of Science ®Google Scholar
• Recklitis, C. J., Sanchez Varela, V., Ng, A., Mauch, P., & Bober, S. (2010). Sexual functioning in long‐term survivors of Hodgkin’s lymphoma. Psycho‐Oncology, 19(11), 1229–1233. doi:10.1002/pon.1679
   PubMed Web of Science ®Google Scholar
• Rosen, R., Cappelleri, J. & Gendrano, N. (2002). The International Index of Erectile Function (IIEF): A state-of-the-science review. International Journal of Impotence Research, 14, 226–244. doi:10.1038/sj.ijir.3900857
   PubMed Web of Science ®Google Scholar
• Rosen, R. C., Riley, A., Wagner, G., Osterloh, I. H., Kirkpatrick, J., & Mishra, A. (1997). The international index of erectile function (IIEF): A multidimensional scale for assessment of erectile dysfunction. Urology, 49(6), 822–830. doi:10.1016/S0090-4295(97)00238-0
   PubMed Web of Science ®Google Scholar
• Sadovsky, R., Basson, R., Krychman, M., Morales, A. M., Schover, L., Wang, R., & Incrocci, L. (2010). Cancer and sexual problems. The journal of sexual medicine, 7(1), 349–373. doi:10.1111/j.1743-6109.2009.01620.x
   PubMed Web of Science ®Google Scholar
• Schover, L. R. (2007). Reproductive complications and sexual dysfunction in cancer survivors. In P. A. Ganz (Eds.), Cancer survivorship (pp. 251–271). New York, NY: Springer. doi:10.1007/978-0-387-68265-5_19
   Google Scholar
• Schover, L. R., van der Kaaij, M., van Dorst, E., Creutzberg, C., Huyghe, E., & Kiserud, C. E. (2014). Sexual dysfunction and infertility as late effects of cancer treatment. European journal of cancer supplements, 12(1), 41–53. doi:10.1016/j.ejcsup.2014.03.004
   Google Scholar
• Silvestri, A., Galetta, P., Cerquetani, E., Marazzi, G., Patrizi, R., Fini, M., & Rosano, G. M. (2003). Report of erectile dysfunction after therapy with beta-blockers is related to patient knowledge of side effects and is reversed by placebo. European heart journal, 24(21), 1928–1932. doi:10.1016/j.ehj.2003.08.016
   PubMed Web of Science ®Google Scholar
• Syrjala, K. L., Kurland, B. F., Abrams, J. R., Sanders, J. E., & Heiman, J. R. (2008). Sexual function changes during the 5 years after high-dose treatment and hematopoietic cell transplantation for malignancy, with case-matched controls at 5 years. Blood, The Journal of the American Society of Hematology, 111(3), 989–996. doi:10.1182/blood-2007-06-096594
   Web of Science ®Google Scholar
• Syrjala, K. L., Langer, S. L., Abrams, J. R., Storer, B. E., & Martin, P. J. (2005). Late effects of hematopoietic cell transplantation among 10-year adult survivors compared with case-matched controls. Journal of Clinical Oncology, 23(27), 6596–6606. doi:10.1200/JCO.2005.12.674
   PubMed Web of Science ®Google Scholar
• Syrjala, K. L., Langer, S. L., Abrams, J. R., Storer, B., Sanders, J. E., Flowers, M. E., & Martin, P. J. (2004). Recovery and long-term function after hematopoietic cell transplantation for leukemia or lymphoma. JAMA, 291(19), 2335–2343. doi:10.1001/jama.291.19.2335
   PubMed Web of Science ®Google Scholar
• Syrjala, K. L., Martin, P., Deeg, J., & Boeckh, M. (2007). Medical and psychosocial issues in transplant survivors. In P. A. Ganz (Eds.), Cancer survivorship (pp. 188–114). New York, NY: Springer. doi:10.1007/978-0-387-68265-5_15
   Google Scholar
• Syrjala, K. L., Schoemans, H., Jean, C. Y., Langer, S. L., Mukherjee, A., Onstad, L., & Lee, S. J. (2021). Sexual functioning in long-term survivors of hematopoietic cell transplantation. Transplantation and cellular therapy, 27(1), 80–e1. doi:10.1016/j.bbmt.2020.09.027
   Google Scholar
• Syrjala, K. L., Schroeder, T. C., Abrams, J. R., Atkins, T. Z., Brown, W. S., Sanders, J. E., … Heiman, J. R. (2000). Sexual function measurement and outcomes in cancer survivors and matched controls. Journal of Sex Research, 37(3), 213–225. doi:10.1080/00224490009552042
   Web of Science ®Google Scholar
• Tichelli, A., Bhatia, S., & Socié, G. (2008). Cardiac and cardiovascular consequences after haematopoietic stem cell transplantation. British journal of hematology, 142(1), 11–26. doi:10.1111/j.1365-2141.2008.07165.x
   PubMed Web of Science ®Google Scholar
• Tierney, D. K. (2008). Sexuality: A quality-of-life issue for cancer survivors. In Seminars in Oncology Nursing (Vol. 24, pp. 71–79). WB Saunders. doi:10.1016/j.soncn.2008.02.001
   Google Scholar
• Tsatsou, I., Mystakidou, K., Panagou, E., Adamakidou, T., Kalemikerakis, I., Vastardi, M., & Gkovina, O. (2020). Sexuality and quality of life of patients with hematologic malignancy and hematopoietic stem cell transplantation: A critical review. J BUON, 25, 1693–1706.
   PubMed Web of Science ®Google Scholar
• Wong, F. L., Francisco, L., Togawa, K., Kim, H., Bosworth, A., Atencio, L., … Bhatia, S. (2013). Longitudinal trajectory of sexual functioning after hematopoietic cell transplantation: Impact of chronic graft-versus-host disease and total body irradiation. Blood, The Journal of the American Society of Hematology, 122(24), 3973–3981. doi:10.1182/blood-2013-05-499806
   Web of Science ®Google Scholar
• Yi, J. C., & Syrjala, K. L. (2009). Sexuality after hematopoietic stem cell transplantation. Cancer Journal (Sudbury, Mass.), 15(1), 57. doi:10.1097/PPO.0b013e318198c758
   PubMed Web of Science ®Google Scholar