Cannabis use by women during pregnancy does not influence infant DNA methylation of the dopamine receptor DRD4

References

• Roth CK, Satran LA, Smith SM. Marijuana use in pregnancy. Nurs Women’s Health 2015;19:431–437.
   PubMedGoogle Scholar
• Calvigioni D, Hurd YL, Harkany T, Keimpema E. Neuronal substrates and functional consequences of prenatal cannabis exposure. Eur Child Adolesc Psychiatry 2014;23:931–941.
   PubMed Web of Science ®Google Scholar
• Cook J, Lloyd-Jones DM, Ogden E, Bonomo Y. Medical use of cannabis: an addiction medicine perspective. Intern Med J 2015;45:677–680.
   PubMed Web of Science ®Google Scholar
• Gunn JKL, Rosales CB, Center KE, Nuñez A, Gibson SJ, Christ C, Ehiri JE. Prenatal exposure to cannabis and maternal and child health outcomes: a systematic review and meta-analysis. BMJ Open 2016;6:e009986.
   Google Scholar
• Brown SJ, Mensah FK, Ah Kit J, Stuart-Butler D, Glover K, Leane C, Weetra D, et al. Use of cannabis during pregnancy and birth outcomes in an Aboriginal birth cohort: a cross-sectional, population-based study. BMJ Open 2016;6:e010286.
   Google Scholar
• Goldschmidt L, Richardson GA, Willford J, Day NL. Prenatal marijuana exposure and intelligence test performance at age 6. J Am Acad Child Adolesc Psychiatry 2008;47:254–263.
   PubMed Web of Science ®Google Scholar
• El Marroun H, Hudziak JJ, Tiemeier H, Creemers H, Steegers EA, Jaddoe VW, Hofman A, et al. Intrauterine cannabis exposure leads to more aggressive behavior and attention problems in 18-month-old girls. Drug Alcohol Depend 2011;118:470–474.
   PubMed Web of Science ®Google Scholar
• Goldschmidt L, Richardson GA, Cornelius MD, Day NL. Prenatal marijuana and alcohol exposure and academic achievement at age 10. Neurotoxicol Teratol 2004;26:521–532.
   PubMed Web of Science ®Google Scholar
• Sharma P, Murthy P, Bharath MM. Chemistry, metabolism, and toxicology of cannabis: clinical implications. Iran J Psychiatry 2012;7:149–156.
   PubMedGoogle Scholar
• Costa MA. The endocannabinoid system: a novel player in human placentation. Reprod Toxicol 2016;61:58–67.
   PubMed Web of Science ®Google Scholar
• Vaiserman AM. Long-term health consequences of early-life exposure to substance abuse: an epigenetic perspective. J Dev Orig Health Dis 2013;4:269–279.
   PubMed Web of Science ®Google Scholar
• Lan N, Chiu MP, Ellis L, Weinberg J. Prenatal alcohol exposure and prenatal stress differentially alter glucocorticoid signaling in the placenta and fetal brain. Neuroscience 2015; 342:167–179.
   Google Scholar
• Liu J, Chen J, Ehrlich S, Walton E, White T, Perrone-Bizzozero N, Bustillo J, et al. Methylation patterns in whole blood correlate with symptoms in schizophrenia patients. Schizophr Bull 2014;40:769–776.
   PubMed Web of Science ®Google Scholar
• Morris CV, DiNieri JA, Szutorisz H, Hurd YL. Molecular mechanisms of maternal cannabis and cigarette use on human neurodevelopment. Eur J Neurosci 2011;34:1574–1583.
   PubMed Web of Science ®Google Scholar
• Rice ME, Patel JC. Somatodendritic dopamine release: recent mechanistic insights. Philos Trans R Soc Lond B Biol Sci 2015;370:1672.
   Web of Science ®Google Scholar
• Bobadilla L, Vaske J, Asberg K. Dopamine receptor (D4) polymorphism is related to comorbidity between marijuana abuse and depression. Addict Behav 2013;38:2555–2562.
   PubMed Web of Science ®Google Scholar
• Di Ciano P, Pushparaj A, Kim A, Hatch J, Masood T, Ramzi A, Khaled MA, et al. The impact of selective Dopamine D2, D3 and D4 ligands on the rat gambling task. Plos One 2015;10: e0136267.
   PubMed Web of Science ®Google Scholar
• Baker TE, Stockwell T, Barnes G, Haesevoets R, Holroyd CB. Reward sensitivity of ACC as an intermediate phenotype between DRD4-521T and substance misuse. J Cogn Neurosci 2016;28:460–471.
   PubMed Web of Science ®Google Scholar
• Wazana A, Moss E, Jolicoeur-Martineau A, Graffi J, Tsabari G, Lecompte V, Pascuzzo K, et al. The interplay of birth weight, dopamine receptor D4 gene (DRD4), and early maternal care in the prediction of disorganized attachment at 36 months of age. Dev Psychopathol 2015;27:1145–1161.
   PubMed Web of Science ®Google Scholar
• Money KM, Stanwood GD. Developmental origins of brain disorders: roles for dopamine. Front Cell Neurosci 2013:7:260.
   Web of Science ®Google Scholar
• Markunas CA, Xu Z, Harlid S, Wade PA, Lie RT, Taylor JA, Wilcox AJ. Identification of DNA methylation changes in newborns related to maternal smoking during pregnancy. Environ Health Perspect 2014;122:1147–1153.
   PubMed Web of Science ®Google Scholar
• Joubert BR, Felix JF, Yousefi P, Bakulski KM, Just AC, Breton C, Reese SE, et al. DNA methylation in newborns and maternal smoking in pregnancy: genome-wide consortium meta-analysis. Am J Hum Genet 2016;98:680–696.
   PubMed Web of Science ®Google Scholar
• Kupers LK, Xu X, Jankipersadsing SA, Vaez A, La Bastide-Van Gemert S, Scholtens S, Nolte IM, et al. DNA methylation mediates the effect of maternal smoking during pregnancy on birthweight of the offspring. Int J Epidemiol 2015;44:1224–1237.
   Google Scholar
• Chabarria KC, Racusin DA, Antony KM, Kahr M, Suter MA, Mastrobattista JM, Aagaard KM. Marijuana use and its effects in pregnancy. Am J Obstet Gynecol 2016;215:506.e1–7.
   Google Scholar
• Hutchinson D, Wilson J, Allsop A, Elliott E, Najman J, Burns L, Bartu A, et al. The Triple B Pregnancy Cohort Study: a longitudinal study of the relationship between alcohol, tobacco and other substance use during pregnancy and the health and wellbeing of Australian children and families. 2017;epub.
   Google Scholar
• Van Mil NH, Steegers-Theunissen RPM, Bouwland-Both MI, Verbiest MMPJ, Rijlaarsdam J, Hofman A, Steegers EA, et al. DNA methylation profiles at birth and child ADHD symptoms. J Psychiatr Res 2014;49:51–59.
   PubMed Web of Science ®Google Scholar
• Januar V, Ancelin ML, Ritchie K, Saffery R, Ryan J. BDNF promoter methylation and genetic variation in late-life depression. Transl Psychiatry 2015;5:e619.
   PubMed Web of Science ®Google Scholar
• Ion R, Bernal AL. Smoking and preterm birth. Reprod Sci 2015;22:918-926.
   Google Scholar
• Van De Giessen E, Weinstein JJ, Cassidy CM, Haney M, Dong Z, Ghazzaoui R, Ojeil N, et al. Deficits in striatal dopamine release in cannabis dependence. Mol Psychiatry 2017; 22:68–75.
   Google Scholar
• DiNieri JA, Wang X, Szutorisz H, Spano SM, Kaur J, Casaccia P, Dow-Edwards D, Hurd YL. Maternal cannabis use alters ventral striatal Dopamine D2 gene regulation in the offspring. Biol Psychiatry 2011;70:763–769.
   PubMed Web of Science ®Google Scholar
• Ballard ME, Mandelkern MA, Monterosso JR, Hsu E, Robertson CL, Ishibashi K, Dean AC, London ED. Low Dopamine D2/D3 receptor availability is associated with steep discounting of delayed rewards in methamphetamine dependence. Int J Neuropsychopharmacol 2015;18: pyu119.
   PubMed Web of Science ®Google Scholar
• Olsson CA, Moyzis RK, Williamson E, Ellis JA, Parkinson-Bates M, Patton GC, Dwyer T, et al. Gene-environment interaction in problematic substance use: interaction between DRD4 and insecure attachments. Addict Biol 2013;18:717–726.
   PubMed Web of Science ®Google Scholar
• Mallard TT, Doorley J, Esposito-Smythers CL, McGeary JE. Dopamine D4 receptor VNTR polymorphism associated with greater risk for substance abuse among adolescents with disruptive behavior disorders: preliminary results. Am J Addict 2016;25:56–61.
   PubMed Web of Science ®Google Scholar
• Zohsel K, Buchmann AF, Blomeyer D, Hohm E, Schmidt MH, Esser G, Brandeis D, et al. Mothers’ prenatal stress and their children’s antisocial outcomes: a moderating role for the dopamine D4 receptor (DRD4) gene. J Child Psychol Psychiatry 2014;55:69–76.
   PubMed Web of Science ®Google Scholar
• Dadds MR, Schollar-Root O, Lenroot R, Moul C, Hawes DJ. Epigenetic regulation of the DRD4 gene and dimensions of attention-deficit/hyperactivity disorder in children. Eur Child Adolesc Psychiatry 2016;25:1081–1089.
   Google Scholar
• Australian Institute of Health and Welfare. National Drug Strategy Household Survey Detailed Report 2013. Australian Institute of Health and Welfare; 2014.
   Google Scholar
• El Marroun H, Tiemeier H, Steegers EA, Jaddoe VW, Hofman A, Verhulst FC, van den Brink W, Huizink AC. Intrauterine cannabis exposure affects fetal growth trajectories: the Generation R Study. J Am Acad Child Adolesc Psychiatry 2009;48:1173–1181.
   PubMed Web of Science ®Google Scholar
• Wong CC, Caspi A, Williams B, Craig IW, Houts R, Ambler A, Moffitt TE, Mill J. A longitudinal study of epigenetic variation in twins. Epigenetics 2010;5:516–526.
   PubMed Web of Science ®Google Scholar