Low rates of thiamine prescribing in adult patients with alcohol-related diagnoses in the emergency department

References

• Grant BF, Goldstein RB, Saha TD, Chou SP, Jung J, Zhang H, Pickering RP, Ruan WJ, Smith SM, Huang B, et al. Epidemiology of DSM-5 alcohol use disorder. JAMA Psychiatry. 2015;72:757–66.
   PubMed Web of Science ®Google Scholar
• American Psychiatric Association. Diagnostic and Statistical manual of mental disorders. 5th ed.; 2013. https://dsm.psychiatryonline.org/doi/https://doi.org/10.1176/appi.books.9780890425596.dsm16#CHDIBCJD.
   Google Scholar
• Hammoud N, Jimenez-Shahed J. Chronic Neurologic Effects of Alcohol. Clin Liver Dis. 2019;23:141–55. doi:https://doi.org/10.1016/j.cld.2018.09.010.
   PubMed Web of Science ®Google Scholar
• Harper C. Wernicke’s Encephalopathy: A more common disease than realised. A neuropathological study of 51 cases. J Neurol Neurosurg Psychiatry. 1979;42:226–31. doi:https://doi.org/10.1136/jnnp.42.3.226.
   PubMed Web of Science ®Google Scholar
• Harper C. The Incidence of Wernicke’s Encephalopathy in Australia - a neuropathological study of 131 cases. J Neurol Neurosurg Psychiatry. 1983;46:593–98. doi:https://doi.org/10.1136/jnnp.46.7.593.
   PubMed Web of Science ®Google Scholar
• Torvik A, Lindboe CF, Rogde S. Brain lesions in alcoholics. A neuropathological study with clinical correlations. J Neurol Sci. 1982;56:233–48. doi:https://doi.org/10.1016/0022-510X(82)90145-9.
   PubMed Web of Science ®Google Scholar
• Galvin R, Bråthen G, Ivashynka A, Hillbom M, Tanasescu R, Leone MA. EFNS guidelines for diagnosis, therapy and prevention ff Wernicke Encephalopathy. Eur J Neurol. 2010;17:1408–18. doi:https://doi.org/10.1111/j.1468-1331.2010.03153.x.
   PubMed Web of Science ®Google Scholar
• Isenberg-Grzeda E, Kutner HE, Nicolson SE. Wernicke-Korsakoff-syndrome: under-recognized and under-treated. Psychosomatics. 2012;53:507–16. doi:https://doi.org/10.1016/j.psym.2012.04.008.
   PubMed Web of Science ®Google Scholar
• Latt N, Dore G. Thiamine in the treatment of wernicke encephalopathy in patients with alcohol use disorders. Intern Med J. 2014;44:911–15. doi:https://doi.org/10.1111/imj.12522.
   PubMed Web of Science ®Google Scholar
• Donnino MW, Vegav J, Miller J, Walsh M. Myths and misconceptions of Wernicke’s Encephalopathy: what every emergency physician should know. Ann Emerg Med. 2007;50:715–21. doi:https://doi.org/10.1016/j.annemergmed.2007.02.007.
   PubMed Web of Science ®Google Scholar
• Day E, Bentham PW, Callaghan R, Kuruvilla T, George S. Thiamine for prevention and treatment of Wernicke-Korsakoff syndrome in people who abuse alcohol. Cochrane Database Syst Rev. 2013;2013:7. doi:https://doi.org/10.1002/14651858.CD004033.pub3.
   Google Scholar
• Hoffman RS. Thiamine hydrochloride. In: Nelson LS, Howland MA, Lewin NA, Smith SW, Goldfrank LR, Hoffman RS, editors. Goldfrank’s toxicologic emergencies. 11 ed. New York (NY): McGraw Hill Education; 2019. p. 1175–1164.
   Google Scholar
• Sanvisens A, Zuluaga P, Fuster D, Rivas I, Tor J, Marcos M, Chamorro AJ, Muga R. Long-term mortality of patients with an alcohol-related Wernicke–Korsakoff syndrome. Alcohol Alcohol. 2017;52:466–71.
   PubMed Web of Science ®Google Scholar
• Wrenn KD, Murphy F, Slovis CM, Toxicity A. Study of parenteral thiamine hydrochloride. Ann Emerg Med. 1989;18:867–70. doi:https://doi.org/10.1016/S0196-0644(89)80215-X.
   PubMed Web of Science ®Google Scholar
• Tjugum SL, Hedrick TL, Jean SJ, Heeney SA, Rohde KA, Campbell-Bright SL. Evaluation of the safety of intravenous thiamine administration in a large academic medical center. J Pharm Pract. September 2019:089719001987258. doi:https://doi.org/10.1177/0897190019872584.
   Google Scholar
• Kumar PD. Thiamine shortage – plight of low-cost, lifesaving orphan drugs. N Engl J Med. 2006;354:532–33. doi:https://doi.org/10.1056/NEJMc053127.
   PubMed Web of Science ®Google Scholar
• White AM, Slater ME, Ng G, Hingson R, Breslow R. Trends in alcohol-related emergency department visits in the United States: results from the nationwide emergency department sample, 2006 to 2014. Alcohol Clin Exp Res. 2018;42:352–59. doi:https://doi.org/10.1111/acer.13559.
   PubMed Web of Science ®Google Scholar
• Maguire D, Talwar D, Burns A, Catchpole A, Stefanowicz F, Robson G, Ross DP, Young D, Ireland A, Forrest E, et al. A prospective evaluation of thiamine and magnesium status in relation to clinicopathological characteristics and 1-year mortality in patients with alcohol withdrawal syndrome. J Transl Med. 2019;17:384.
   PubMed Web of Science ®Google Scholar
• Ismail MF, Doherty K, Bradshaw P, O’Sullivan I, Cassidy EM. Symptom-triggered therapy for assessment and management of alcohol withdrawal syndrome in the emergency department short-stay clinical decision unit. Emerg Med J. 2018;36. emermed-2017-206997. DOI:https://doi.org/10.1136/emermed-2017-206997.
   Google Scholar
• ICD-10-CM tabular list of diseases and injuries. Centers for Medicare & Medicaid Services. Published 2020 [accessed 2021 Feb 1]. https://www.cms.gov/Medicare/Coding/ICD10/2020-ICD-10-CM.
   Google Scholar
• Isenberg-Grzeda E, Chabon B, Nicolson SE. Prescribing thiamine to inpatients with alcohol use disorders: how well are we doing? J Addict Med. 2014;8:1–5. doi:https://doi.org/10.1097/01.ADM.0000435320.72857.c8.
   PubMed Web of Science ®Google Scholar
• Thomson AD. The Royal college of physicians report on alcohol: guidelines for managing Wernicke’s encephalopathy in the accident and emergency department. Alcohol Alcohol. 2002;37:513–21. doi:https://doi.org/10.1093/alcalc/37.6.513.
   PubMed Web of Science ®Google Scholar
• Tallaksen CME, Sande A, Bøhmer T, Bell H, Karlsen J. Kinetics of thiamin and thiamin phosphate esters in human blood, plasma and urine after 50 Mg intravenously or orally. Eur J Clin Pharmacol. 1993;44:73–78. doi:https://doi.org/10.1007/BF00315284.
   PubMed Web of Science ®Google Scholar
• Baines M, Bligh JG, Madden JS. Tissue thiamin levels of hospitalised alcoholics before and after oral or parenteral vitamins. Alcohol Alcohol. 1988;23:49–52. doi:https://doi.org/10.1093/oxfordjournals.alcalc.a044754.
   PubMed Web of Science ®Google Scholar
• Thomson AD, Cook CCH. Parenteral thiamine and wernicke’s encephalopathy: the balance of risks and perception of concern. Alcohol Alcohol. 1997;32:207–09. doi:https://doi.org/10.1093/oxfordjournals.alcalc.a008259.
   PubMed Web of Science ®Google Scholar
• Alim U, Bates D, Langevin A, Werry D, Dersch-Mills D, Herman RJ, Mintz M, Ghosh S. Thiamine prescribing practices for adult patients admitted to an internal medicine service. Can J Hosp Pharm. 2017;70:179–87.
   PubMed Web of Science ®Google Scholar
• Wheeler M. Thiamine injection – current drug shortages. American Society of Health-System Pharmacists. Published 2018. accessed 2020 Aug 1]. https://www.ashp.org/Drug-Shortages/Current-Shortages/Drug-Shortage-Detail.aspx?id=387.
   Google Scholar
• Schabelman E, Kuo D. Glucose before thiamine for wernicke encephalopathy: a literature review. J Emerg Med. 2012;42:488–94. doi:https://doi.org/10.1016/j.jemermed.2011.05.076.
   PubMed Web of Science ®Google Scholar
• Nabipour S, Ayu Said M, Hussain Habil M. Burden and nutritional deficiencies in opiate addiction- systematic review article. Iran J Public Health. 2014; 43: 1022–32. http://www.ncbi.nlm.nih.gov/pubmed/25927032.
   PubMed Web of Science ®Google Scholar
• Li SF, Jacob J, Feng J, Kulkarni M. Vitamin deficiencies in acutely intoxicated patients in the Ed. Am J Emerg Med. 2008;26:792–95. doi:https://doi.org/10.1016/j.ajem.2007.10.003.
   PubMed Web of Science ®Google Scholar
• Schwab RA, Powers RD. Prevalence of folate deficiency in emergency department patients with alcohol-related illness or injury. Am J Emerg Med. 1992;10:203–07. doi:https://doi.org/10.1016/0735-6757(92)90209-G.
   PubMed Web of Science ®Google Scholar
• Krishel S, Safranek D, Clark RF. Intravenous vitamins for alcoholics in the emergency department: a review. J Emerg Med. 1998;16:419–24. doi:https://doi.org/10.1016/S0736-4679(98)00007-9.
   PubMedGoogle Scholar
• Faine B, Nunge M, Denning G, Nugent A. Implementing evidence-based changes in emergency department treatment: alternative vitamin therapy for alcohol-related illnesses. Ann Emerg Med. 2012;59:408–12. doi:https://doi.org/10.1016/j.annemergmed.2011.06.021.
   PubMed Web of Science ®Google Scholar
• Flannery AH, Adkins DA, Cook AM. Unpeeling the evidence for the banana bag: evidence-based recommendations for the management of alcohol-associated vitamin and electrolyte deficiencies in the ICU. Crit Care Med. 2016;44:1545–52. doi:https://doi.org/10.1097/CCM.0000000000001659.
   PubMed Web of Science ®Google Scholar