114
Views
0
CrossRef citations to date
0
Altmetric
Original Article

Prevalence and correlates of DSM-5 opioid withdrawal syndrome in U.S. adults with non-medical use of prescription opioids: results from a national sample

, , , ORCID Icon & ORCID Icon
Pages 799-808 | Received 30 Nov 2022, Accepted 13 Aug 2023, Published online: 10 Nov 2023

References

  • Centers for Disease Control and Prevention. Atlanta (GA): CDC, National Center for Health Statistics. https://www.cdc.gov/drugoverdose/rxrate-maps/index.html.
  • Centers for Disease Control and Prevention. Atlanta (GA): CDC, National Center for Health Statistics; 2022. http://wonder.cdc.gov.2021.
  • Centers for Disease Control and Prevention. Atlanta (GA): CDC, National Center for Health Statistics. https://www.cdc.gov/nchs/nvss/vsrr/drug-overdose-data.htm.
  • Substance Abuse and Mental Health Service Adminstration. Key substance use and mental health indicators in the United States: results from the 2019 National survey on Drug use and health (HHS Publication No. PEP20-07-01-001, NSDUH Series H-55). Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration; 2020. https://www.samhsa.gov/data/
  • American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 5th ed. 2013. doi:10.1176/appi.books.9780890425596.
  • Pergolizzi JV, Varrassi G, Paladini A, LeQuang J. Stopping or decreasing opioid therapy in patients on chronic opioid therapy. Pain Ther. 2019;8:163–76. doi:10.1007/s40122-019-00135-6.
  • Northrup TF, Stotts AL, Green C, Potter JS, Marino EN, Walker R, Weiss RD, Trivedi M. Opioid withdrawal, craving, and use during and after outpatient buprenorphine stabilization and taper: a discrete survival and growth mixture model. Addict Behav. 2015;41:20–28. doi:10.1016/j.addbeh.2014.09.021.
  • Langabeer JR, Stotts AL, Bobrow BJ, Wang HE, Chambers KA, Yatsco AJ, Cardenas-Turanzas M, Champagne-Langabeer T. Prevalence and charges of opioid-related visits to U.S. emergency departments. Drug Alcohol Depend. 2021;221:108568. doi:10.1016/j.drugalcdep.2021.108568.
  • Slater T, Rodney T, Kozachik SL, Finnell DS. Recommendations for emergency departments caring for persons with opioid use and opioid use disorders: an integrative review. J Emerg Nurs. 2022;48:129–44. doi:10.1016/j.jen.2021.11.003.
  • Amato L, Davoli M, Minozzi S, Ferroni E, Ali R, Ferri M. Methadone at tapered doses for the management of opioid withdrawal. Cochrane Database Syst Rev. 2013;28:CD003409. doi:10.1002/14651858.CD003409.pub4.
  • Baxley C, Weinstock J, Lustman PJ, Garner AA. The influence of anxiety sensitivity on opioid use disorder treatment outcomes. Exp Clin Psychopharmacol. 2019;27:64–77. doi:10.1037/pha0000215.
  • Bluthenthal RN, Simpson K, Ceasar RC, Zhao J, Wenger L, Kral AH. Opioid withdrawal symptoms, frequency, and pain characteristics as correlates of health risk among people who inject drugs. Drug Alcohol Depend. 2020;211:107932. doi:10.1016/j.drugalcdep.2020.107932.
  • Srivastava AB, Mariani JJ, Levin FR. New directions in the treatment of opioid withdrawal. Lancet. 2020;395:1938–48. doi:10.1016/S0140-6736(20)30852-7.
  • Torres-Lockhart KE, Lu TY, Weimer MB, Stein MR, Cunningham CO. Clinical management of opioid withdrawal. Addiction. 2022;117:2540–50. doi:10.1111/add.15818.
  • Strain E, Saxon AJ, Hermann R. Opioid use disorder: epidemiology, pharmacology, clinical manifestations, course, screening, assessment, and diagnosis. UpToDate. Waltham (MA): UpToDate; 2018.
  • JV P Jr, Raffa RB, Rosenblatt MH. Opioid withdrawal symptoms, a consequence of chronic opioid use and opioid use disorder: Current understanding and approaches to management. J Clin Pharm Ther. 2020 Oct;45:892–903. doi:10.1111/jcpt.13114. Epub 2020 Jan 27.
  • Arroyo-Novoa CM, Figueroa-Ramos MI, Puntillo KA. Opioid and benzodiazepine iatrogenic withdrawal syndrome in patients in the intensive care unit. AACN Adv Crit Care. 2019 Dec 15;30:353–64. doi:10.4037/aacnacc2019267.
  • Kosten TR, Baxter LE. Review article: effective management of opioid withdrawal symptoms: a gateway to opioid dependence treatment. Am J Addict. 2019;28:55–62. doi:10.1111/ajad.12862.
  • Kimmel SD, Kim JH, Kalesan B, Samet JH, Walley AY, Larochelle MR. Against medical advice discharges in injection and non-injection Drug use-associated infective endocarditis: a nationwide cohort study. Clin Infect Dis. 2021;73:e2484–e92. doi:10.1093/cid/ciaa1126.
  • Simon R, Snow R, Wakeman S. Understanding why patients with substance use disorders leave the hospital against medical advice: a qualitative study. Subst Abus. 2020;41:519–25. doi:10.1080/08897077.2019.1671942.
  • Southern WN, Nahvi S, Arnsten JH. Increased risk of mortality and readmission among patients discharged against medical advice. Am J Med. 2012;125:594–602. doi:10.1016/j.amjmed.2011.12.017.
  • Coloma-Carmona A, Carballo JL, Rodríguez-Marín J, Pérez-Carbonell A. Withdrawal symptoms predict prescription opioid dependence in chronic pain patients. Drug Alcohol Depend. 2019;195:27–32. doi:10.1016/j.drugalcdep.2018.11.013.
  • Hasin DS, Fenton MC, Beseler C, Park JY, Wall MM. Analyses related to the development of DSM-5 criteria for substance use related disorders: 2. Proposed DSM-5 criteria for alcohol, cannabis, cocaine and heroin disorders in 663 substance abuse patients. Drug Alcohol Depend. 2012;122:28–37. doi:10.1016/j.drugalcdep.2011.09.005.
  • Martins SS, Sarvet A, Santaella-Tenorio J, Saha T, Grant BF, Hasin DS. Changes in US lifetime heroin use and heroin use disorder: prevalence from the 2001-2002 to 2012-2013 national epidemiologic survey on alcohol and related conditions. JAMA Psychiarty. 2017 1;74: 445–55. 10.1001/jamapsychiatry.2017.0113.
  • Grant BF, Goldstein RB, Smith SM, Jung J, Zhang H, Chou SP, Pickering RP, Ruan WJ, Huang B, Saha TD, et al. The Alcohol Use Disorder and Associated Disabilities Interview Schedule-5 (AUDADIS-5): reliability of substance use and psychiatric disorder modules in a general population sample. Drug Alcohol Depend. 148;27–33. 10.1016/j.drugalcdep.2014.11.026. Epub 2014 Dec 8. PMID: 25595052; PMCID: PMC5554948.
  • Hasin DS, Greenstein E, Aivadyan C, Stohl M, Aharonovich E, Saha T, Goldstein R, Nunes EV, Jung J, Zhang H, et al. The Alcohol Use Disorder and Associated Disabilities Interview Schedule-5 (AUDADIS-5): procedural validity of substance use disorders modules through clinical re-appraisal in a general population sample. Drug Alcohol Depend. 2015 Mar 1;148:40–46. 10.1016/j.drugalcdep.2014.12.011. Epub 2014 Dec 18. PMID: 25604321; PMCID: PMC4330104.
  • Ware JJ, Kosinski M, Keller SD. A 12-item short-form health survey: construction of scales and preliminary tests of reliability and validity. Med Care. 1996 Mar;34:220–33. doi:10.1097/00005650-199603000-00003.
  • Burdine JN, Felix MR, Abel AL, Wiltraut CJ, Musselman YJ. The SF-12 as a population health measure: an exploratory examination of potential for application. Health Serv Res. 2000 Oct;35:885–904.
  • Jenkinson C, Layte R, Jenkinson D, Lawrence K, Petersen S, Paice C, Stradling J. A shorter form health survey: can the SF-12 replicate results from the SF-36 in longitudinal studies? J Public Health Med. 1997 Jun;19: 179–86. doi:10.1093/oxfordjournals.pubmed.a024606.
  • Krantz MJ, Palmer RB, Haigney MCP. Cardiovascular complications of opioid use: JACC state-of-the-Art review. J Am Coll Cardiol. 2021 Jan 19. 77;205–23. doi:10.1016/j.jacc.2020.11.002. PMID: 33446314.
  • Jairam V, Yang DX, Verma V, Yu JB, Park HS. National patterns in prescription opioid use and misuse among cancer survivors in the United States. JAMA Netw Open. 2020 Aug 3;3:e2013605. doi:10.1001/jamanetworkopen.2020.13605. PMID: 32804217; PMCID: PMC7431994.
  • Szigethy E, Knisely M, Drossman D. Opioid misuse in gastroenterology and non-opioid management of abdominal pain. Nat Rev Gastroenterol Hepatol. 2018 Mar;15:168–80. doi:10.1038/nrgastro.2017.141. Epub 2017 Nov 15. PMID: 29139482; PMCID: PMC6421506.
  • Rodríguez-Espinosa S, Coloma-Carmona A, Pérez-Carbonell A, Román-Quiles JF, Carballo JL. Clinical and psychological factors associated with interdose opioid withdrawal in chronic pain population. J Subst Abuse Treat. 2021 Oct;129:108386. doi:10.1016/j.jsat.2021.108386.
  • Cicero TJ, Ellis MS. The prescription opioid epidemic: a review of qualitative studies on the progression from initial use to abuse. Dialogues Clin Neurosci. 2017 Sep;19:259–69. doi:10.31887/DCNS.2017.19.3/tcicero.
  • Gowing L, Ali R, White JM, Mbewe D. Buprenorphine for managing opioid withdrawal. Cochrane Database Syst Rev. 2017 Feb 21;2:CD002025. doi:10.1002/14651858.CD002025.pub5. PMID: 28220474; PMCID: PMC6464315.
  • Chakravorty S, Vandrey RG, He S, Stein MD. Sleep management among patients with substance use disorders. Med Clin North Am. 2018 Jul;102:733–43. doi:10.1016/j.mcna.2018.02.012.
  • Darke S, Larney S, Farrell M. Yes, people can die from opiate withdrawal. Addiction. 2017 Feb;112:199–200. doi:10.1111/add.13512. Epub 2016 Aug 11.
  • Duber HC, Barata IA, Cioè-Peña E, Liang SY, Ketcham E, Macias-Konstantopoulos W, Ryan SA, Stavros M, Identification WL. Management, and transition of care for patients with opioid use disorder in the emergency department. Ann Emerg Med. 2018 Oct;72:420–31. doi:10.1016/j.annemergmed.2018.04.007. Epub 2018 Jun 5.
  • Fava GA, Benasi G, Lucente M, Offidani E, Cosci F, Guidi J. Withdrawal symptoms after serotonin-noradrenaline reuptake inhibitor discontinuation: systematic review. Psychother Psychosom. 2018;87:195–203. doi:10.1159/000491524. Epub 2018 Jul 17. PMID: 30016772.
  • McCance-Katz EF, Sullivan LE, Nallani S. Drug interactions of clinical importance among the opioids, methadone and buprenorphine, and other frequently prescribed medications: a review. Am J Addict. 2010 Jan–Feb;19:4–16. doi:10.1111/j.1521-0391.2009.00005.x.
  • Martins SS, Fenton MC, Keyes KM, Blanco C, Zhu H, Storr CL. Mood and anxiety disorders and their association with non-medical prescription opioid use and prescription opioid-use disorder: longitudinal evidence from the National Epidemiologic study on Alcohol and related conditions. Psychol Med. 2012 Jun;42:1261–72. doi:10.1017/S0033291711002145. Epub 2011 Oct 17.
  • Koob GF. Neurobiology of opioid Addiction: opponent process, hyperkatifeia, and negative reinforcement. Biol Psychiatry. 2020 Jan 1;87:44–53. doi:10.1016/j.biopsych.2019.05.023. Epub 2019 Jun 12.
  • Donroe JH, Holt SR, Tetrault JM. Caring for patients with opioid use disorder in the hospital. CMAJ. 2016 Dec 6;188:1232–39. doi:10.1503/cmaj.160290. Epub 2016 Sep 19.
  • Vivolo-Kantor AM, Seth P, Gladden RM, Mattson CL, Baldwin GT, Kite-Powell A, Coletta MA. Vital signs: trends in emergency department visits for suspected opioid overdoses - United States, July 2016-September 2017. MMWR Morb Mortal Wkly Rep. 2018 Mar 9;67:279–85. doi:10.15585/mmwr.mm6709e1.
  • Substance Abuse and Mental Health Services Administration. Preliminary findings from drug-related emergency department visits, 2021; drug abuse warning network. Rockville, MD: Center for Behavioral Health Statistics and Quality, Substance Abuse and Mental Health Services Administration. 2022. HHS Publication No. PEP22-07-03-001. https://www.samhsa.gov/data/.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.