TRIBUTYLTIN INDUCES HUMAN NEUTROPHIL APOPTOSIS AND SELECTIVE DEGRADATION OF CYTOSKELETAL PROTEINS BY CASPASES

References

• Colucci-Guyon , E. , Portier , M. M. , Dunia , I. , Paulin , D. , Pournin , S. and Babinet , C. 1994 . Mice lacking vimentin develop and reproduce without an obvious phenotype . Cell , 79 : 679 – 694 .
   PubMed Web of Science ®Google Scholar
• Dransfield , I. , Buckle , A. M. , Savill , J. S. , McDowall , A. , Haslett , C and Hogg , N. 1994 . Neutrophil apoptosis is associated with a reduction in CD16 (Fc gamma RIII) expression . J. lmmunol. , 153 : 1254 – 1263 .
   PubMed Web of Science ®Google Scholar
• Elferink , J. G. , Deierkauf , M. and Van Steveninck , J. 1986 . Toxicity of organotin compounds for polymorphonuclear leukocytes: The effect on +phagocytosis and exocytosis . Biochem. Pharmacol. , 35 : 3727 – 3732 .
   PubMed Web of Science ®Google Scholar
• Fadeel , B. , Ahlin , A. , Henter , J. I. , Orienius , S. and Hampton , M. B. 1998 . Involvement of caspases in neutrophil apoptosis: Regulation by reactive oxygen species . Blood , 92 : 4808 – 4818 .
   PubMed Web of Science ®Google Scholar
• Gennari , A. , Potters , M , Seinen , W. and Pieters , R. 1997 . Organotin-induced apoptosis as observed in vitro is not relevant for induction of thymus atrophy at antiproliferative doses . Toxicol. Appl. Pharmacol. , 147 : 259 – 266 .
   PubMed Web of Science ®Google Scholar
• Gennari , A. , Viviani , B. , Galli , C. L , Marinovich , M. , Pieters , R. and Corsini , E. 2000 . Organotins induce apoptosis by disturbance of (Ca(2+))(i) and mitochondrial activity, causing oxidative stress and activation of caspases in rat thymocytes . Toxicol. Appl. Pharmacol. , 169 : 185 – 190 .
   PubMed Web of Science ®Google Scholar
• Girard , D. , Paquet , M. E. , Paquin , R. and Beau lieu , A. D. 1996 . Differential effects of interleukin-15 (IL-15) and IL-2 on human neutrophils: Modulation of phagocytosis, cytoskeletal rearrangement, gene expression, and apoptosis by IL-15 . Blood , 88 : 3176 – 3184 .
   PubMed Web of Science ®Google Scholar
• Heerdt , B. G. , Houston , M. A. , Anthony , G. M and Augenlicht , L H. 1999 . Initiation of growth arrest and apoptosis of MCF-7 mammary carcinoma cells by tributyrin, a triglyceride analogue of the short-chain fatty acid butyrate, is associated with mitochondrial activity . Cancer Res. , 59 : 1584 – 1591 .
   PubMed Web of Science ®Google Scholar
• Kannan , K. , Villeneuve , D. L , Blankenship , A. L and Giesy , J. P. 1998 . Interaction of tributyltin with 3,3',4,4',5-pentachlorobiphenyl-induced ethoxyresorufin O-deethylase activity in rat hepatoma cells . J. Toxicol. Environ. Health A , 55 : 373 – 384 .
   PubMed Web of Science ®Google Scholar
• Karpiak , V. C , Bridges , R. J. and Eyer , C. L . 2001 . Organotins disrupt components of glutamate homeostasis in rat astrocyte cultures . J. Toxicol. Environ. Health A , 63 : 273 – 287 .
   PubMed Web of Science ®Google Scholar
• Kergosien , D. H. and Rice , C. D. 1998 . Macrophage secretory function is enhanced by low doses of tributyltin-oxide (TBTO), but not tributyltin-chbride (TBTCI) . Arch. Environ. Contam. Toxicol. , 34 : 223 – 228 .
   PubMed Web of Science ®Google Scholar
• Kothakota , S. , Azuma , T. , Reinhard , C , Klippel , A. , Tang , J. , Chu , K. , McGarry , T. J. , Kirschner , M. W. , Koths , K. , Kwiatkowski , D. J. and Williams , L T. 1997 . Caspase-3-generated fragment of gelsolin: Effector of morphological change in apoptosis . Science , 278 : 294 – 298 .
   PubMed Web of Science ®Google Scholar
• Lin , J. L and Hsueh , S. 1993 . Acute nephropathy of organotin compounds . Am. J. Nephrol. , 13 : 124 – 128 .
   PubMed Web of Science ®Google Scholar
• Lin , T. J. , Hung , D. Z. , Kao , C. H. , Hu , W. H. and Yang , D. Y. 1998 . Unique cerebral dysfunction following triphenyltin acetate poisoning . Hum. Exp. Toxicol. , 17 : 403 – 405 .
   PubMed Web of Science ®Google Scholar
• Marinovich , M. , Sanghvi , A. , CoIIi , S. , Tremoli , E. and GaIIi , C. L . 1990 . Cytoskeletal modifications induced by organotin compounds in human neutrophils . Toxicol. In Vitro , 4 : 109 – 114 .
   PubMed Web of Science ®Google Scholar
• Matsui , H. , Wada , O , Ushijima , Y. and Mizuta , T. 1983 . Inhibition of oxidative metabolism in rabbit polymorphonuclear leukocytes by triphenyltin chloride . Arch. Toxicol. , 54 : 227 – 233 .
   PubMed Web of Science ®Google Scholar
• Miura , Y. and Matsui , H. 1989 . Inhibition by triphenyltin chloride of cytosolic free calcium mobilization in human neutrophils stimulated by a chemotactic factor . Res. Commun. Chem. Pathol. Pharmacol. , 64 : 331 – 341 .
   PubMedGoogle Scholar
• Mizuhashi , S. , lkegaya , Y. and Matsuki , N. 2000 . Cytotoxicity of tributyltin in rat hippocampal slice cultures . Neurosci. Res. , 38 : 35 – 42 .
   PubMed Web of Science ®Google Scholar
• Morishima , N. 1999 . Changes in nuclear morphology during apoptosis correlate with vimentin cleavage by different caspases located either upstream or downstream of Bc1-2 action . Genes Cells , 4 : 401 – 414 .
   PubMed Web of Science ®Google Scholar
• Ogata , R. , Omura , M , Shimasaki , Y. , Kubo , K. , Oshima , Y. , Aou , S. and Inoue , N. 2001 . Two-generation reproductive toxicity study of tributyltin chloride in female rats . J. Toxicol. Environ. Health A , 63 : 127 – 144 .
   PubMed Web of Science ®Google Scholar
• Takubo , T and Tatsumi , N. 1999 . Microscopic co-distributions of myosin, actin, alpha-actinin and vinculin in human neutrophils during movement . Haematologia (Budap.) , 29 : 285 – 294 .
   PubMedGoogle Scholar
• Tan , L. P. , Ng , M. L and Kumar Das , V. G. 1978 . The effect of trialkyltin compounds on tubulin polymerisation . J. Neurochem. , 31 : 1035 – 1041 .
   PubMed Web of Science ®Google Scholar
• Whalen , M. M. , Loganathan , B. G. and Kannan , K. 1999 . Immunotoxicity of environmentally relevant concentrations of butyltins on human natural killer cells in vitro . Environ. Res. , 81 : 108 – 116 .
   PubMed Web of Science ®Google Scholar
• Arakawa , Y. and Wada , O. 1984 . Inhibition of neutrophil chemotaxis by organotin mpounds . Biochem. Biophys. Res. Commun. , 123 : 543 – 548 .
   PubMed Web of Science ®Google Scholar
• Aw , T. Y. , Nicotera , P. , Manzo , L and Orrenius , S. 1990 . Tributyltin stimulates apoptosis in rat thymocytes . Arch. Biochem. Biophys. , 283 : 46 – 50 .
   PubMed Web of Science ®Google Scholar
• Bhatia , M. , Kirkland , J. B. and Meckling-Gill , K. A. 1995 . Modulation of poly (ADP-ribose) polymerase during neutrophilc and monocytic differentiation of promyelocytic (NB4) and myelocytic (HL-60) leukaemia cells . Biochem. J. , 308 : 131 – 137 .
   PubMed Web of Science ®Google Scholar
• Viviani , B. , Rossi , A. D. , Chow , S. C and Nicotera , P. 1995 . Organotin compounds induce calcium overload and apoptosis in PC12 cells . Neurotoxicology , 16 : 19 – 25 .
   PubMed Web of Science ®Google Scholar
• Yuruker , B. and Niggli , V. 1992 . Alpha-actinin and vinculin in human neutrophils: Reorganization during adhesion and relation to the actin network . J. Cell Sci. , 101 : 403 – 414 .
   PubMed Web of Science ®Google Scholar
• Zucker , R. M. , Elstein , K. H. , Thomas , D. J. and Rogers , J. M. 1994 . Tributyltin and dexamethasone induce apoptosis in rat thymocytes by mutually antagonistic mechanisms . Toxicol. Appl. Pharmacol. , 127 : 163 – 170 .
   PubMed Web of Science ®Google Scholar
• Bondy , S. C and Hall , D. L . 1986 . The relation of the neurotoxicity of organic tin and lead compounds to neurotubule disaggregation . Neurotoxicology , 7 : 51 – 55 .
   PubMed Web of Science ®Google Scholar
• Chow , S. C. , Kass , G. E. , McCabe , M. J. , Jr. and Orrenius , S. 1992 . Tributyltin increases cytosolic free Ca2+ concentration in thymocytes by mobilizing intracellular Ca2+ , activating a Ca2+ entry pathway, and inhibiting Ca2+ efflux . Arch. Biochem. Biophys. , 298 : 143 – 149 .
   PubMed Web of Science ®Google Scholar
• Cima , F. , Ballarin , L , Bressa , G. and Burighel , P. 1998a . Cytoskeleton alterations by tributyltin (TBT) in tunicate phagocytes . Ecotoxicol. Environ. Safety , 40 : 160 – 165 .
   PubMed Web of Science ®Google Scholar
• Cima , F. , Marin , M. G. , Matozzo , V. , Da Ros , L and Ballarin , L . 1998b . Immunotoxic effects of organotin compounds in Tapes philippinarum . Chemosphere , 37 : 3035 – 3045 .
   PubMed Web of Science ®Google Scholar
• Corsini , E. , Bruccoleri , A , Marinovich , M. and Galli , C. L . 1996 . Endogenous interleukin-1 alpha associated with skin irritation induced by tributyltin . Toxicol. Appl. Pharmacol. , 138 : 268 – 274 .
   PubMed Web of Science ®Google Scholar
• DeLong , G. T. and Rice , C. D. 1997 . Tributyltin potentiates 3,3',4,4',5-pentachlorobiphenyl-induced cytochrome P-4501 A-related activity . J. Toxicol. Environ. Health , 51 : 131 – 148 .
   PubMed Web of Science ®Google Scholar
• Negri , A. P. and Heyward , A. J. 2001 . Inhibition of coral fertilisation and larval metamorphosis by tributyltin and copper . Mar. Environ. Res. , 51 : 17 – 27 .
   PubMed Web of Science ®Google Scholar
• Nishimura , G. , Proske , R. J. , Doyama , H. and Higuchi , M. 2002 . Regulation of apoptosis by respiration: Cytochrome c release by respiratory substrates . FEBS Lett. , 505 : 399 – 404 .
   Web of Science ®Google Scholar
• Stridh , H. , Orrenius , S. and Hampton , M. B. 1999b . Caspase involvement in the induction of apoptosis by the environmental toxicants tributyltin and triphenyltin . Toxicol. Appl. Pharmacol. , 156 : 141 – 146 .
   PubMed Web of Science ®Google Scholar
• Yamanoshita , O , Kurasaki , M , Saito , T , Takahasi , K. , Sasaki , H. , Hosokawa , T. , Okabe , M. , Mochida , J and Iwakuma , T. 2000 . Diverse effect of tributyltin on apoptosis in PC12 cells . Biochem. Biophys. Res. Commun. , 272 : 557 – 562 .
   PubMed Web of Science ®Google Scholar
• Slee , E. A. , Adrain , C and Martin , S. J. 2001 . Executioner caspases-3, -6 and -7 perform distinct, non-redundant, roles during the demolition phase of apoptosis . J. Biol. Chem. , 276 : 7320 – 7326 .
   PubMed Web of Science ®Google Scholar
• Snoeij , N. J. , Penninks , A. H. and Seinen , W. 1987 . Biological activity of organotin compounds--An overview . Environ. Res. , 44 : 335 – 353 .
   PubMed Web of Science ®Google Scholar
• Snoeij , N. J. , Penninks , A. H. and Seinen , W. 1989 . Thymus atrophy and immunosuppression induced by organotin compounds . Arch. Toxicol. Suppl. , 13 : 171 – 174 .
   PubMedGoogle Scholar
• Stridh , H. , Kimland , M. , Jones , D. P. , Orrenius , S. and Hampton , M. B. 1998 . Cytochrome c release and caspase activation in hydrogen peroxide-and tributyltin-induced apoptosis . FEBS Lett. , 429 : 351 – 355 .
   PubMed Web of Science ®Google Scholar
• Stridh , H. , Gigliotti , D. , Orrenius , S. and Cotgreave , 1. 1999a . The role of calcium in pre-and postmitochondrial events in tributyltin-induced T-cell apoptosis . Biochem. Biophys. Res. Commun. , 266 : 460 – 465 .
   PubMed Web of Science ®Google Scholar
• Pryzwansky , K. B , Wyatt , T. A. and Lincoln , T. M. 1995 . Cyclic guanosine monophosphate-dependent protein kinase is targeted to intermediate filaments and phosphorylates vimentin in A23187-stimulated human neutrophils . Blood , 85 : 222 – 230 .
   PubMed Web of Science ®Google Scholar
• Raffray , M , McCarthy , D. , Snowden , R. T. and Cohen , G. M. 1993 . Apoptosis as a mechanism of tributyltin cytotoxicity to thymocytes: Relationship of apoptotic markers to biochemical and cellular effects . Toxicol. Appl. Pharmacol. , 119 : 122 – 130 .
   PubMed Web of Science ®Google Scholar
• Reader , S. , Moutardier , V. and Denizeau , F. 1999 . Tributyltin triggers apoptosis in trout hepatocytes: the role of Ca2+ , protein kinase C and pro teases . Biochim. Biophys. Acta , 1448 : 473 – 478 .
   PubMed Web of Science ®Google Scholar
• Rice , C. D. and Roszell , L E. 1998 . Tributyltin modulates 3,3',4,4',5-pentachlorobiphenyl (PCB-126)-induced hepatic CYP1A activity in channel catfish, lctalurus punctatus . J. Toxicol. Environ. Health A , 55 : 197 – 212 .
   PubMed Web of Science ®Google Scholar
• Ryu , H. , Lee , J. H. , Kim , K. S. , Jeong , S. M. , Kim , P. H. and Chung , H. T. 2000 . Regulation of neutrophil adhesion by pituitary growth hormone accompanies tyrosine phosphorylation of Jak2, p125FAK, and paxillin . J. Immunol. , 165 : 2116 – 2123 .
   PubMed Web of Science ®Google Scholar
• Sanghavi , D. M , Thelen , M , Thornberry , N. A. , Casciola-Rosen , L and Rosen , A. 1998 . Caspase-mediated proteolysis during apoptosis: Insights from apoptotic neutrophils . FEBS Lett. , 422 : 179 – 184 .
   PubMed Web of Science ®Google Scholar
• Savoie , A. , Lavastre , V. , Pelletier , M , Hajto , T. , Hostanska , K. and Girard , D. 2000 . Activation of human neutrophils by the plant lectin Viscum album agglutinin-I: Modulation of de novo protein synthesis and evidence that caspases are involved in induction of apoptosis . J. Leukocyte Biol. , 68 : 845 – 853 .
   PubMed Web of Science ®Google Scholar
• Serrander , L , Skarman , P. , Rasmussen , B. , Witke , W. , Lew , D. P. , Krause , K. H. , Stendahl , O. and Nusse , O. 2000 . Selective inhibition of IgG-mediated phagocytosis in gelsolin-deficient in urine neutrophils . J. Immunol. , 165 : 2451 – 2457 .
   PubMed Web of Science ®Google Scholar