POLYCYCLIC AROMATIC HYDROCARBON-DNA ADDUCTS IN BELUGA WHALES FROM THE ARCTIC

References

• Dunn , B. P. , Black , J. J. , and Maccubbin , A. 1987 . 32P-postlabeling analysis of aromatic DNA adducts in fish from polluted areas . Cancer Res. 47 6543 – 6548 .
   PubMed Web of Science ®Google Scholar
• Gelboin , H. V. 1980 . Benzo(a)pyrene metabolism, activation and carcinogenesis Role and regulation of mixed-function oxidases and related enzymes . Physiol. Rev. 60 1107 – 1166 .
   PubMed Web of Science ®Google Scholar
• Heidelberger , C. 1976 . Studies on the mechanisms of carcinogenesis by polycyclic aromatic hydrocarbons and their derivatives . In Carcinogenesis—A Comprehensive Survey , vol. I Polynuclear Aromatic Hydrocarbons Chemistry, Metabolism and Carcinogenesis, edited by R. Freudenthal and P. W. Jones , pp. 1 – 8 . New York Raven Press .
   Google Scholar
• International Agency for Research on Cancer. 1993 . Postlabelling Methods for the Detection of DNA Adducts , edited by D. H. Phillips , M. Castegnaro , and H. Bartsch , IARC Scientific Publications No. 124 . Lyon , France International Agency for Research on Cancer .
   Google Scholar
• Kurelec , B. , Carg , A. , Krca , S. , Chacko , M. , and Gupta , R. C. 1989 . Natural environment surpasses polluted environment in inducing DNA damage in fish . Carcinogenesis 10 1337 – 1339 .
   PubMed Web of Science ®Google Scholar
• Martineau , D. , DeCuise , S. , Fournier , M. , Shugart , L , Cirard , C , Lagace , A. , and Beland , P. 1994 . Pathology and toxicology of beluga whales from the St. Lawrence Estuary, Quebec Canada. Past, present and future . Sci. Total Environ. 154 201 – 215 .
   PubMed Web of Science ®Google Scholar
• Muir , D. C. C , Wagemann , R. , Hargrave , B. T. , Thomas , D. J. , Peakall , D. B. , and Norstrom , R. J. , 1992 . Arctic marine ecosystem contamination . Sci. Total Environ. 122 : 75 – 134
   Google Scholar
• Payne , J. F. , Kiceniuk , J. , Fancey, L L, Williams , U. , Fletcher , C. L , Rahimtula , A. , and Fowler , B. 1988 . What is a safe level of polycyclic aromatic hydrocarbons for fish Subchronic toxicity study on winter flounder (Pseudopleuronectes americanus) . Can. J. Fish. Aquat.Sci. 45 1983 – 1993 .
   Web of Science ®Google Scholar
• Poirier , M. C. 1994 . Human exposure monitoring, dosimetry, and cancer risk assessment The use of antisera specific for carcinogen–DNA adducts and carcinogen modified DNA . Drug Metab. Rev. 26 87 – 109 .
   PubMed Web of Science ®Google Scholar
• Randerath , K. , Putnam , K. L , Osterburg , H. H. , Johnson , S. A. , Morgan , D. C , and Finch , C. E. 1993 . Age-dependent increases of DNA–adducts (l-compounds) in human and rat-brain DNA . Mutat.Res. 295 11 – 18 .
   PubMed Web of Science ®Google Scholar
• Ray , S. , Dunn , B. P. , Payne , J. F. , Fancey , L. L , and Beland , P. 1992 . Aromatic DNA-carcino-gen adducts in beluga whales from the Canadian Arctic and Gulf of St. Lawrence . Mar. Pollut. Bull. 22 392 – 396 .
   Web of Science ®Google Scholar
• Santella , R. M. , Weston , A. , Perera , F. P. , Trivers , C. T. , Harris , C. C. , Young , T. L. , Nguyen , D. , Lee , B. M. , and Poirier , M. C. 1988 . Interlaboratory comparison of antisera and immunoassays for benzo(a)pyrene-diol-epoxide-l-modified DNA . Carcinogenesis 9 1265 – 1269 .
   PubMed Web of Science ®Google Scholar
• Santodonato , J. , Howard , P. , and Basu , D. 1981 . Health and ecological assessment of polynu-clear aromatic hydrocarbons . J. Environ. Pathol. Toxicol. 5 1 – 16 .
   PubMed Web of Science ®Google Scholar
• Stein , J. E. , Reichert , W. L. , and Varanasi , U. 1994 . Molecular epizootiology Assessment of exposure to genotoxic compounds in teleosts . Environ. Health Perspect . 102 19 – 23 .
   PubMed Web of Science ®Google Scholar
• Stowers , S. J. , and Anderson , M. W. 1985 . Formation and persistence of benzo(a)pyrene metabo-lite-DNA adducts . Environ. Health Perspect . 62 31 – 39 .
   PubMed Web of Science ®Google Scholar