AMIODARONE-INDUCED PULMONARY TOXICITY IN FISCHER RATS: RELEASE OF TUMOR NECROSIS FACTOR ALPHA AND TRANSFORMING GROWTH FACTOR BETA BY PULMONARY ALVEOLAR MACROPHAGES

References

• Akoun , C. M. , Liote, C, Milleron , B. J. , and Mayaud , C. M. 1987 . Amiodarone lung. In Current topics in pulmonary pharmacology and toxicology , ed. M. A. Hollinger , pp. 176 – 194 . New Yor Elsevier .
   Google Scholar
• Beddows , S. A. , Page , S. R. , Taylor , A. H. , McNerney , R. , Withley, C. St. J., Johnstone , A. P. , and Nussey , S. S. 1989 . Cytotoxic effects of amiodarone and desethylamiodarone on human thyrocytes . Biochem. Pharmacol . 38 4397 – 4403 .
   PubMed Web of Science ®Google Scholar
• Danielpour , D. , Dart, L. L, Flanders, K. C, Roberts , A. B. , and Sporn , M. B. 1989 . Immunodetection and quantification of the two forms of transforming growth factor-beta (TGF-B1 and TCF-P2) secreted by cells in culture . J. Cell. Physiol . 138 79 – 86 .
   PubMed Web of Science ®Google Scholar
• Daniels , J. M. , Brien , J. F. , and Massey , T. E. 1989 . Pulmonary fibrosis induced in the hamster by amiodarone and desethylamiodarone . Toxicol. Appl. Pharmacol . 100 350 – 359 .
   PubMed Web of Science ®Google Scholar
• Dayer , J.-M. , Beutler , B. , and Cerami , A. 1985 . Cachectin/tumor necrosis factor stimulates collage-nase and prostaglandin E2 production by human synovial cells and dermal fibroblasts . J. Exp. Med . 162 2163 – 2168 .
   PubMed Web of Science ®Google Scholar
• Cross , S. A. , Bandyopadhyay , S. , Klaunig , J. E. , and Somani , P. 1989 . Amiodarone and desethylamiodarone toxicity in isolated hepatocytes in culture . Proc. Soc. Exp. Biol. Med . 190 163 – 169 .
   PubMed Web of Science ®Google Scholar
• Hajjar , K. A. , Hajjar , D. P. , Silverstein, R. L,Nachman, R. L 1987 . Tumor necrosis factor-mediated release of platelet-derived growth factor from cultured endothelial cells . J. Exp. Med . 166 235 – 245 .
   PubMed Web of Science ®Google Scholar
• Hoyt , D. C , and Lazo , J. S. 1988 a. Alterations in pulmonary mRNA encoding procollagens, fibronectin and transforming growth factor-P precede bleomycin-induced pulmonary fibrosis in mice . J. Pharmacol. Exp. Trier . 246 765 – 771 .
   PubMed Web of Science ®Google Scholar
• Hoyt , D. C , and Lazo , J. S. 1988 b. Early increases in pulmonary mRNA encoding procollagens and transforming growth factor-p in mice sensitive to cyclophosphamide-induced pulmonary fibrosis . J. Pharmacol. Exp. Ther . 249 38 – 43 .
   Web of Science ®Google Scholar
• Ignotz , R. A. , and Massague , J. 1986 . Transforming growth factor-p stimulates the expression of fibronectin and collagen and their incorporation into the extracellular matrix . J. Biol. Chem . 261 4337 – 4345 .
   PubMed Web of Science ®Google Scholar
• Israel-Biet , D. , Venet , A. , Caubarrere , I. , Bonan , C , Danel , C , Chretien , J. , and Hance , A. J. 1987 . Bronchoalveolar lavage in amiodarone pneumonitis Cellular abnormalities and their relevance to pathogenesis . Chest 91 214 – 221 .
   PubMed Web of Science ®Google Scholar
• Kohase , M. , Henriksen-DeStefano , D. , May , L. T. , Vilcek , J. , Sehgal . P. B. 1986 . Induction of p2-interferon by tumor necrosis factor A homeostatic mechanism in the control of cell proliferation . Cell 45 659 – 666 .
   PubMed Web of Science ®Google Scholar
• Kramer , S. M. , and Carver , M. E. 1986 . Serum-free in vitro bioassay for the detection of tumor necrosis factor . J. Immunol. Methods 93 201 – 206 .
   PubMed Web of Science ®Google Scholar
• Le , J. , Weinstein , D. , Gubler , U. , and Vilcek , J. 1987 . Induction of membrane-associated inter-leukin 1 by tumor necrosis factor in human fibroblasts . J. Immunol . 138 2137 – 2142 .
   PubMed Web of Science ®Google Scholar
• Martin , W. J. II , Rosenow , E. C. III . 1988 . Amiodarone pulmonary toxicity. Recognition and pathogenesis . Chest 93 1067 – 1075 .
   PubMed Web of Science ®Google Scholar
• Matsushima , K. , Morishita , K. , and Yoshimura , T. , Lavu , Sukadev , Kobayashi , Y. , Lew , W. , Appella , E. , Kung , H. S. , Leonard , E. J. , and Oppenheim , J. J. 1988 . M olecular cloning of a human monocyte-derived neutrophil chemotactic factor (MDNCF) and the induction of MDNCF mRNA by interleukin-1 and tumor necrosis factor . J. Exp. Med . 167 1883 – 1893 .
   PubMed Web of Science ®Google Scholar
• Nawroth , P. P. , Bank , I. , Handley , D. , Cassimeris , J. , Chess , L. , and Stern , D. 1986 . Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of inter-leukin 1 . J. Exp. Med . 163 1363 – 1375 .
   PubMed Web of Science ®Google Scholar
• Ogle , C. L. , and Reasor , M. J. 1990 . Response of alveolar macrophages to amiodarone and desethylamiodarone, in vitro . Toxicology 62 227 – 238 .
   PubMed Web of Science ®Google Scholar
• Penttinen , R. P. , Kobayashi , S. , and Bornstein , P. 1988 . Transforming growth factor p increases mRNA for matrix proteins both in the presence and absence of changes in mRNA stability . Proc. Natl. Acad. Sci . USA 85 1105 – 1108 .
   Google Scholar
• Phan , S. H. , and Kunkel , S. L. 1992 . Lung cytokine production in bleomycin-induced pulmonary fibrosis . Exp. Lung Res . 18 29 ^ p13 p.
   PubMed Web of Science ®Google Scholar
• Piguet , P. F. , Collart , M. A. , Crau , C. E. , Kapanci , Y. , and Vassalli , P. 1989 . Tumor necrosis factor/cachectin plays a key role in bleomycin-induced pneumopathy and fibrosis . J. Exp. Med . 170 655 – 663 .
   PubMed Web of Science ®Google Scholar
• Pober , J. S. , Bevilacqua , M. P. , Mendrick , D. L. , Lapierre , L. A. , Fiers , W. , and Cimbrone , M. A. 1986 . Two distinct monokines, interleukin 1 and tumor necrosis factor, each independently induce biosynthesis and transient expression of the same antigen on the surface of cultured human vascular endothelial cells . J. Immunol . 136 1680 – 1687 .
   PubMed Web of Science ®Google Scholar
• Reasor , M. J. , and Kacew , S. 1990 . Amiodarone pulmonary toxicity Morphologic and biochemical features . Proc. Soc. Exp. Biol. Med . 196 1 – 7 .
   Google Scholar
• Reasor , M. J. , and Kacew , S. 1996 . An evaluation of possible mechanisms underlying amiodarone-induced pulmonary toxicity . Proc. Soc. Exp. Biol. Med . 212 297 – 304 .
   PubMed Web of Science ®Google Scholar
• Reasor , M. J. , Ogle , C. L. , and Kacew , S. 1989 . Amiodarone-induced pulmonary toxicity in rats Biochemical and pharmacological characteristics . Toxicol. Appl. Pharmacol . 97 124 – 133 .
   PubMed Web of Science ®Google Scholar
• Reasor , M. J. , McCloud , C. M. , DiMatteo , M. , Schafer , R. , Ima , A. , and Lemaire , I. 1996 . Effects of amiodarone-induced phospholipidosis on pulmonary host defense functions in rats . Proc. Soc. Exp. Biol. Med . 211 346 – 352 .
   PubMed Web of Science ®Google Scholar
• Reinhart , P. C , Lai , Y.-L. , and Gairbia , C. G. 1996 . Amiodarone-induced pulmonary fibrosis in Fischer 344 rats . Toxicology 110 95 – 101 .
   PubMed Web of Science ®Google Scholar
• Roberts , A. B. , and Sporn , M. B. 1990 . The transforming growth factor betas. In Peptide growth factors and their receptors. Handbook of experimental pharmacology , eds. M. B. Sporn and A. B. Roberts , pp. 419 – 472 . New York Springer-Verlag .
   Google Scholar
• Venet , A. , Caubarrere , I. , and Bonan , C. 1984 . Five cases of immune-mediated amiodarone pneumonitis . Lancet 1 962 – 963 .
   PubMed Web of Science ®Google Scholar
• Vilcek , J. , Palombella , V. J. , Henriksen-DeStefano , D. , Swenson, C, Feinman , R. , Hirai , M. , and Tsujimoto , M. 1986 . Fibroblast growth enhancing activity of tumor necrosis factor and its relationship to other polypeptide growth factors . J. Exp. Med . 163 632 – 643 .
   PubMed Web of Science ®Google Scholar
• Wilson , B. D. , and Lippmann , M. L. 1990 . Pulmonary accumulation of amiodarone and N-desethylamiodarone. Relationship to the development of pulmonary toxicity . Am. Rev. Respir. Dis . 141 1553 – 1558 .
   PubMed Web of Science ®Google Scholar
• Wilson , B. D. , Clarkson , C. E. , and Lippmann , M. L. 1991 . Amiodarone-induced pulmonary inflammation Correlation with drug dose and lung levels of drug, metabolite, and phospholipid . Am. Rev. Respir. Dis . 143 ssssss 1110 – 1114 .
   PubMed Web of Science ®Google Scholar