A SIMPLIFIED ALGORITHM FOR COMPUTING THE VARIATION IN OXYHEMOGLOBIN SATURATION WITH pH, PCO₂, T AND DPG

REFERENCES

• Adair , G.S. , The hemoglobin system. VI. The oxygen dissociation curve of hemoglobin , J. Biol. Chem. , 63 , 529 – 545 , 1925 .
   Google Scholar
• Arturson , G. , Garby , L. , Robert , M. , and Zarr , B. , The oxygen dissociation curve of normal blood with special reference to the influence of physiological effector ligands. Scand . J. Clin. Lab. Invest. , 34 , 9 – 13 , 1974 .
   PubMed Web of Science ®Google Scholar
• Barnhart , M.C. , Micromethod for dynamic determination of O2 dissociation curves using a PO2 electrode . J. Appl. Physiol. , 56 , 795 – 797 , 1984 .
   PubMed Web of Science ®Google Scholar
• Buerk , D.G. , An evaluation of Easton's paradigm for the oxyhemoglobin equilibrium curve . In Oxygen Transport to Tissue-VI, Advances in Experimental Medicine and Biology (Vol. 180 ), Bruley, D., Bircher, H.I. and Reneau, D. (Eds.) , Plenum Press , N.Y ., pp. 333 – 344 , 1985 .
   Google Scholar
• Buerk , D.G. , Nair , P.K. , Bridges , E.W. , and Hanley , T.R. , Interpretation of oxygen disappearance curves measured in blood perfused tissues . In Oxygen Transport to Tissue-VIII, Advances in Experimental Medicine and Biology Series , Longmuir, I.A. (Ed.) , Plenum Press , N.Y . ( in press ).
   Google Scholar
• Dill , D.B. , In Handbook of Respiratory Data in Aviation , Dittmer, D.S. and Grebe, R.M. (Eds.) , National Research Council , Washington , D.C. , pp. 74 – 75 , 1958 .
   Google Scholar
• Easton , D.M. , Oxyhemoglobin dissociation curve as expo-exponential paradigm of asymmetric sigmoid function . J. Theor. Biol. , 76 , 335 – 349 , 1979 .
   PubMed Web of Science ®Google Scholar
• Fell , D.A. , Computer simulation studies of the mixing technique and nonlinear optimization used in the analysis of oxyhemoglobin dissociation . Math. Biosci , 46 , 59 – 69 , 1979 .
   Web of Science ®Google Scholar
• Hill , A.V. , The possible effects of the aggregation of the molecules of hemoglobin on its dissociation curves . J. Physiol . ( London ), 40 , iv, 1910 .
   Google Scholar
• Hlastala , M.P. , and Woodson , R.D. , Saturation dependency of the Bohr effect Interactions among H+, CO2 and DPG . J. Appl. Physiol. , 38 , 1126 – 1131 , 1975 .
   PubMed Web of Science ®Google Scholar
• Kelman , G.R. , Digital computer subroutine for the conversion of oxygen tension into saturation . J. Appl. Physiol. , 21 , 1375 – 1376 , 1966 .
   PubMed Web of Science ®Google Scholar
• Kon , K. , Maeda , N. , Sekiya , M. , Shiga , T. , and Suda , T. , A method for studying oxygen diffusion barrier in erythrocytes effects of haemoglobin content and membrane cholesterol . J. Physiol. , 309 , 569 – 590 , 1980 .
   PubMed Web of Science ®Google Scholar
• O'Riordan , J.F. , Goldstick , T.K. , Vida , L.N. , Honig , G.R. , and Ernest , J.T. , Modelling whole blood oxygen equilibrium Interconversion of oxygen tension and saturation . In Oxygen Transport to Tissue-VII, Advances in Experimental Medicine and Biology (Vol. 191 ), Kreuzer, F., Cain, S.M., Turek, Z. and Goldstick, T.K. (Eds.) , Plenum Press , N.Y , pp. 505 – 522 , 1985 .
   Google Scholar
• Reich , J.G. and Zinke , I. , Analysis of kinetic and binding measurements. IV. Redundancy of model parameters . Studia Biophysica , 43 , 91 – 107 , 1974 .
   Google Scholar
• Roughton , F.J.W. , DeLand , E.C. , Kernohan , J.C. and Severinghaus , J.W. Some recent studies of the oxyhaemoglobin dissociation curve under physiological conditions and the fitting of the Adair Equation to the standard curve . In Oxygen Affinity of Hemoglobin and Red Cell Acid Base Status , Astrup, P. and Rorth, M. (Eds) , Academic Press , N.Y ., pp. 73 – 83 , 1972 .
   Google Scholar
• Severinghaus , J.W., Blood gas calculator . J. Appl. Physiol. , 21 , 1108 – 1116 , 1966 .
   PubMed Web of Science ®Google Scholar
• Severinghaus , J.W. , Simple, accurate expressions for human blood oxygen dissociation computations . J. Appl. Physiol. , 45 , 289 – 297 , 1979 .
   Google Scholar
• Teisseire , B. , Teisseire , L. , Lautier , A. , Herigault , R. Laurent , D. A method of continuous recording on microsamples of the Hb–O2 dissociation curve. I. Technique and direct registration of sta dard results . Bull. Physio-Pathol. Respir. , 8 , 127 – 136 , 1975 .
   Google Scholar
• Winslow , R.M. , Swenberg , M. , Berger , R.L. , Shrager , R.I. , Luzzana , M. Samaja , M. and Rossi-Bernardi , L. Oxygen equilibrium curve of normal human blood and its evaluation by Adair's equation . J. Biol. Chem. , 252 , 2331 – 2337 , 1977 .
   PubMed Web of Science ®Google Scholar
• Winslow , R.M. , Samaja , M. , Winslow , N.J. , Rossi-Bernardi , L. and Shrager , R.I. Simulation of continuous blood O2 equilibrium curve over physiological pH, DPG and PCO2 range . J. Appl. Physiol. , 54 , 524 – 529 , 1983 .
   PubMed Web of Science ®Google Scholar
• Zwart , A. , Kwant , G. , Oseburg , B. and Zijlstra , W.G. Oxygen dissociation curves for whole blood, recorded with an instrument that continuously measures PO2 and SO2 independently at constant T, PCO2 and pH . Clin. Chem. , 28 , 1287 – 1292 , 1982 .
   PubMed Web of Science ®Google Scholar
• Zwart , A. , Kwant , G. , Oseburg , B. and Zijlstra , W.G. Human whole-blood oxygen affinity Effect of temperature . J. Appl. Physiol. , 57 , 429 – 434 , 1984 .
   PubMed Web of Science ®Google Scholar