515
Views
33
CrossRef citations to date
0
Altmetric
Original Article

Role of tranexamic acid in management of dysfunctional uterine bleeding in comparison with medroxyprogesterone acetate

, , &
Pages 673-678 | Published online: 02 Jul 2009

References

  • Bonnar J, Sheppard B L. Treatment of menorrhagia during menstruation: randomised controlled trial of ethamsylate, mefenamic acid and tranexamic acid. British Medical Journal 1996; 313: 579–582
  • Bonnar J, Sheppard B L, Dockeray C J. The haemostatic system and dysfunctional uterine bleeding. Research and Clinical Forums 1983; 5: 27–38
  • Callender S T, Warner G T, Cope E. Treatment of menorrhagia with tranexamic acid: a double blind trial. British Medical Journal 1970; 4: 214–216
  • Cameron I T, Haining R, Lumsden M A, Thomas V R, Smith S K. The effects of mefenamic acid and norethisterone on measured blood loss. Obstetrics and Gynecology 1990; 76: 85–88
  • Coulter A, Kelland J, Peto V, Rees M CP. Treating menorrhagia in primary care: an overview of drug trials and survey of prescribing practice. International Journal of Technology Assessment in Health Care 1995; 11: 456–471
  • Dicker R C, Geenspan J R, Stauss L T, et al. Complications of abdominal and vaginal hysterectomy among women of reproductive age in the United States. American Journal of Obstetrics and Gynaecology 1982; 144: 841–848
  • Fraser I S. Treatment of ovulatory and anovulatory dysfunctional uterine bleeding with oral progesterone. Australian and New Zealand Journal of Obstetrics and Gynaecology 1990; 30: 353–356
  • Fraser I S, McCarron G. Randomised trial of two hormonal and two prostaglandin-inhibiting agents in women with a complaint of menorrhagia. Australian and New Zealand Journal of Obstetrics and Gynaecology 1991; 31: 66–70
  • Gleeson N C, Buggy F, Sheppard B L, Bonnar J. The effect of tranexamic acid on measured menstrual loss and endometrial fibrinolytic enzymes in dysfunctional uterine bleeding. Acta Obstetricia et Gynecologica Scandinavica 1994; 73: 274–277
  • Higham J M, O'Brien P M, Shaw R W. Assessment of menstrual blood loss using a pictorial chart. British Journal of Obstetrics and Gynaecology 1990; 97: 734–739
  • Intercontinental Medical Statistics Ltd. United Kingdom and Ireland. IMS Ltd., London 1994
  • Irvine G A, Cameron I T. Medical management of dysfunctional uterine bleeding. Baillieres Best Practice and Research Clinical Obstetrics and Gynaecology 1999; 13: 189–202
  • Irvine G A, Campbell-Brown M B, Lumsden M A, Heikkila A, Walker J J, Cameron I T. Randomised comparative trial of the levonorgestrel intrauterine system and norethisterone for treatment of idiopathic menorrhagia. British Journal of Obstetrics and Gynaecology 1998; 105: 592–598
  • Kadir R A, Economides D L, Sabin C A, Owens D, Lee C A. Frequency of inherited bleeding disorders in women with menorrhagia. Lancet 1998; 351: 485–489
  • Lethaby A, Irvine G, Cameron I. Cyclical progesterones for heavy menstrual bleeding. Cochrane Database of Systematic Reviews 2000; 2: CD001016
  • Lethaby A, Farquhar C, Cooke I. Antifibrinolytics for heavy menstrual bleeding. Cochrane Database of Systematic Reviews 2001; 4: CD000249
  • Liu D TY. Treatment of dysfunctional uterine bleeding. Amenorrhoea need not be an end point. British Medical Journal 1995; 310: 802
  • Macdonald R. Modern treatment of menorrhagia. British Journal of Obstetrics and Gynaecology 1990; 97: 3–7
  • Milsom I, Anderson K, Andersch B, Rybo G. A comparison of flurbiprofen, tranexamic acid and a levonorgestrel releasing intrauterine contraceptive device in the treatment of idiopathic menorrhagia. American Journal of Obstetrics and Gynecology 1991; 164: 879–883
  • Munro M G. Medical management of abnormal uterine bleeding. Obstetrics and Gynecology Clinics of North America 2000; 27: 287–304
  • Nilsson L, Rybo G. Treatment of menorrhagia with an antifibrinolytic agent, tranexamic acid. Acta Obstetricia et Gynecologica Scandinavica 1967; 46: 572–580
  • Preston J T, Cameron I T, Adams E J, Smith S K. Comparative study of tranexamic acid and norethisterone in the treatment of ovulatory menorrhagia. British Journal of Obstetrics and Gynaecology 1995; 102: 401–406
  • Rybo G. Tranexamic acid therapy; effective treatment in heavy menstrual bleeding. Therapeutic Advances 1991; 4: 1–8
  • Rydin E, Lundberg P O. Letter: Tranexamic acid and intracranial thrombosis. Lancet 1976; 2: 49
  • Wellington K, Wagstaff A J. Tranexamic acid: A review of its use in the management of Menorrhagia. Drugs 2003; 63: 1417–1433

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.