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Journal of Obstetrics and Gynaecology Volume 26, 2006 - Issue 8
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Original Article

Pregnancy outcome following use of large doses of vitamin B6 in the first trimester

A. Shrim The Motherisk Program, Division of Clinical Pharmacology/Toxicology, Hospital for Sick Children, University of Toronto, Ontario, CanadaCorrespondence[email protected]
,
R. Boskovic The Motherisk Program, Division of Clinical Pharmacology/Toxicology, Hospital for Sick Children, University of Toronto, Ontario, Canada
,
C. Maltepe The Motherisk Program, Division of Clinical Pharmacology/Toxicology, Hospital for Sick Children, University of Toronto, Ontario, Canada
,
Y. Navios The Motherisk Program, Division of Clinical Pharmacology/Toxicology, Hospital for Sick Children, University of Toronto, Ontario, Canada
,
F. Garcia–Bournissen The Motherisk Program, Division of Clinical Pharmacology/Toxicology, Hospital for Sick Children, University of Toronto, Ontario, Canada
&
G. Koren The Motherisk Program, Division of Clinical Pharmacology/Toxicology, Hospital for Sick Children, University of Toronto, Ontario, Canada
Pages 749-751 | Published online: 02 Jul 2009

References

  • Atanackovic G, Navioz Y, Moretti M E, Koren G. The safety of higher than standard dose of doxylamine-pyridoxine (Diclectin) for nausea and vomiting of pregnancy. Journal of Clinical Pharmacology 2001; 41: 842–845
  • Canadian Pharmacists Association. CPS – Compendium of Pharmaceuticals and Specialties. Canadian Pharmacists Association, Canada 1999
  • Cohen M, Bendich A. Safety of pyridoxine – a review of human and animal studies. Toxicology Letters 1986; 34: 129–139
  • Einarson T R, Leeder J S, Koren G. A method for meta-analysis of epidemiological studies. Drug Intelligence and Clinical Pharmacy 1988; 22: 813–824
  • Furneaux E C, Langley-Evans A J, Langley-Evans S C. Nausea and vomiting of pregnancy: endocrine basis and contribution to pregnancy outcome. Obstetrics and Gynecology Surveys 2001; 56: 775–782
  • Gadsby R, Barnie-Adshead A M, Jagger C. A prospective study of nausea and vomiting during pregnancy. British Journal of General Practice 1993; 43: 245–248
  • McKeigue P M, Lamm S H, Linn S, Kutcher J S. Bendectin and birth defects: I. A meta-analysis of the epidemiologic studies. Teratology 1994; 50: 27–37
  • Neutel C I. Variation in rates of hospitalization for excessive vomiting in pregnancy by Bendectin ‘Diclectin’ use in Canada. Nausea and vomiting of pregnancy: State of the art 2000, G Koren, R Bishai. Motherisk, Toronto 2000; 54–59
  • Sahakian V, Rouse D, Sipes S, Rose N, Niebyl J. Vitamin B6 is effective therapy for nausea and vomiting of pregnancy: a randomized, double-blind placebo-controlled study. Obstetrics and Gynecology 1991; 78: 33–36
  • Schaumburg H, Kaplan J, Windebank A, Vick N, Rasmus S, Pleasure D, et al. Sensory neuropathy from pyridoxine abuse. A new megavitamin syndrome. New England Journal of Medicine 1983; 309: 445–448
  • Vutyavanich T, Wongtra-ngan S, Ruangsri R. Pyridoxine for nausea and vomiting of pregnancy: a randomized, double-blind, placebo-controlled trial. American Journal of Obstetrics and Gynecology 1995; 173: 881–884

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