Postpartum human breast milk levels of neutrophil gelatinase-associated lipocalin (NGAL) and matrix metalloproteinase-9 (MMP-9)/NGAL complex in normal and pregnancies complicated with insulin-dependent gestational diabetes mellitus. A prospective pilot case-control study

References

• Abaci A, Catli G, Anik A, Kume T, Bober E. 2013. The relation of serum nesfatin-1 level with metabolic and clinical parameters in obese and healthy children. Pediatric Diabetes 14:189–195.
   PubMed Web of Science ®Google Scholar
• Aydin S. 2010. The presence of the peptides apelin, ghrelin and nesfatin-1 in the human breast milk, and the lowering of their levels in patients with gestational diabetes mellitus. Peptides 31:2236–2240.
   PubMed Web of Science ®Google Scholar
• Aydin S, Kuloglu T, Aydin S. 2013. Copeptin, adropin and irisin concentrations in breast milk and plasma of healthy women and those with gestational diabetes mellitus. Peptides 47:66–70.
   PubMed Web of Science ®Google Scholar
• Aydin S, Celik O, Gurates B, Sahin I, Ulas M, Yilmaz M, et al. 2013. Concentrations of preptin, salusins and hepcidins in plasma and milk of lactating women with or without gestational diabetes mellitus. Peptides 49:123–130.
   PubMed Web of Science ®Google Scholar
• Aydin S, Geckil H, Karatas F, Donder E, Kumru S, Kavak EC, et al. 2007. Milk and blood ghrelin level in diabetics. Nutrition 23:807–811.
   PubMed Web of Science ®Google Scholar
• Castan-Laurell I, Dray C, Attané C, Duparc T, Knauf C, Valet P, et al. 2011. Apelin, diabetes, and obesity. Endocrine 40:1–9.
   PubMed Web of Science ®Google Scholar
• Cheung PY, Sawicki G, Gross S, Van Aerde J, Radomski M. 2001. Differential expression of matrix metalloproteinases and the tissue inhibitor in human milk. Proceedings of the Western Pharmacology Society 44:97–98.
   PubMedGoogle Scholar
• Costantini S, Di Capua E, Zerega B, Nicoletti L, Corticelli A, Descalzi Cancedda F, et al. 2002. Pilot study on lipocalin expression into extracellular fluids of women in fertile age. Minerva Ginecologica 54:387–392.
   PubMedGoogle Scholar
• Coustan DR, Lowe LP, Metzger BE, Dyer AR; International Association of Diabetes and Pregnancy Study Groups. 2010. The hyperglycemia and adverse pregnancy outcome (HAPO) study: paving the way for new diagnostic criteria for gestational diabetes mellitus. American Journal of Obstetrics and Gynecology 202:e1–6.
   PubMed Web of Science ®Google Scholar
• Crowther CA, Hiller JE, Moss JR, McPhee AJ, Jeffries WS, Robinson JS, et al. 2005. Australian Carbohydrate Intolerance Study in Pregnant Women (ACHOIS) Trial Group. Effect of treatment of gestational diabetes mellitus on pregnancy outcomes. The New England Journal of Medicine 352:2477–2486.
   PubMed Web of Science ®Google Scholar
• D’Anna R, Baviera G, Corrado F, Giordano D, Recupero S, Di Benedetto A. 2009a. First trimester serum neutrophil gelatinase-associated lipocalin in gestational diabetes. Diabetic Medicine 26:1293–1295.
   PubMed Web of Science ®Google Scholar
• D’ Anna R, Baviera G, Giordano D, Russo S, Dugo N, Santamaria A, Corrado F. 2009b. First trimester serum PAPP-A and NGAL in the prediction of late-onset pre-eclampsia. Prenatal Diagnosis 29:1066–1068.
   PubMed Web of Science ®Google Scholar
• D’ Anna R, Baviera G, Giordano D, Todarello G, Corrado F, Buemi M. 2008. Second trimester neutrophil gelatinase-associated lipocalin as a potential prediagnostic marker of preeclampsia. Acta Obstetricia et Gynecologica Scandinavica 87:1370–1373.
   PubMed Web of Science ®Google Scholar
• D’ Anna R, Baviera G, Giordano D, Todarello G, Russo S, Recupero S. et al. 2010. Neutrophil gelatinase-associated lipocalin serum evaluation through normal pregnancy and in pregnancies complicated by preeclampsia. Acta Obstetricia et Gynecologica Scandinavica 89:275–278.
   PubMed Web of Science ®Google Scholar
• Dabelea D, Snell-Bergeon JK, Hartsfield CL, Bischoff KJ, Hamman RF, McDuffie RS, et al. 2005. Increasing prevalence of gestational diabetes mellitus (GDM) over time and by birth cohort: Kaiser Permanente of Colorado GDM screening program. Diabetes Care 28:579–584.
   PubMed Web of Science ®Google Scholar
• de Bruyn M, Arijs I, De Hertogh G, Ferrante M, Van Assche G, Rutgeerts P, et al. 2015. Serum neutrophil gelatinase B-associated lipocalin and matrix metalloproteinase-9 complex as a surrogate marker for mucosal healing in patients with Crohn’s disease. Journal of Crohn’s and Colitis 9:1079–1087.
   PubMed Web of Science ®Google Scholar
• Farrar D, Simmonds M, Bryant M, Sheldon TA, Tuffnell D, Golder S, et al. 2016. Hyperglycaemia and risk of adverse perinatal outcomes: systematic review and meta-analysis. The BMJ 354:i4694.
   PubMed Web of Science ®Google Scholar
• Fernandez CA, Yan L, Louis G, Yang J, Kutok JL, Moses MA. 2005. The matrix metalloproteinase-9/neutrophil gelatinaseassociated lipocalin complex plays a role in breast tumor growth and is present in the urine of breast cancer patients. Clinical Cancer Research 11:5390–5395.
   PubMed Web of Science ®Google Scholar
• Flower DR. 1996. The lipocalin protein family: structure and function. Biochemical Journal 318:1–14.
   PubMed Web of Science ®Google Scholar
• Goetz DH, Holmes MA, Borregaard N, Bluhm ME, Raymond KN, Strong RK, et al. 2002. The neutrophil lipocalin NGAL is a bacteriostatic agent that interferes with siderophore-mediated iron acquisition. Molecular Cell 10:1033–1043.
   PubMed Web of Science ®Google Scholar
• Goetz DH, Willie ST, Armen RS, Bratt T, Borregaard N, Strong RK, et al. 2000. Ligand preference inferred from the structure of neutrophil gelatinase associated lipocalin. Biochemistry 39:1935–1941.
   PubMed Web of Science ®Google Scholar
• Hillier TA, Pedula KL, Schmidt MM, Mullen JA, Charles MA, Pettitt DJ, et al. 2007. Childhood obesity and metabolic imprinting: the ongoing effects of maternal hyperglycemia. Diabetes Care 30:2287.
   PubMed Web of Science ®Google Scholar
• Jiwani A, Marseille E, Lohse N, Damm P, Hod M, Kahn JG, et al. 2012. Gestational diabetes mellitus: results from a survey of country prevalence and practices. Journal of Maternal-Fetal and Neonatal Medicine 25:600–610.
   PubMed Web of Science ®Google Scholar
• Karampas G, Eleftheriades M, Panoulis K, Rizou M, Haliassos A, Hassiakos D, et al. 2014. Maternal serum levels of neutrophil gelatinase-associated lipocalin (NGAL), matrix metalloproteinase-9 (MMP-9) and their complex MMP-9/NGAL in pregnancies with preeclampsia and those with a small for gestational age neonate: a longitudinal study. Prenatal Diagnosis 34:726–733.
   PubMed Web of Science ®Google Scholar
• Kjeldsen L, Johnsen AH, Sengeløv H, Borregaard N. 1993. Isolation and primary structure of NGAL, a novel protein associated with human neutrophil gelatinase. Journal of Biological Chemistry 268:10425–10432.
   PubMed Web of Science ®Google Scholar
• Kjeldsen L, Bainton DF, Sengeløv H, Borregaard N. 1994. Identification of neutrophil gelatinase-associated lipocalin as a novel matrix protein of specific granules in human neutrophils. Blood 83:799–807.
   PubMed Web of Science ®Google Scholar
• Landon MB, Spong CY, Thom E, Carpenter MW, Ramin SM, Casey B, et al. 2009. A multicenter, randomized trial of treatment for mild gestational diabetes. New England Journal of Medicine 361:1339–1348.
   PubMed Web of Science ®Google Scholar
• Librach CL, Werb Z, Fitzgerald ML, Chiu K, Corwin NM, Esteves RA, et al. 1991. 92-kD type IV collagenase mediates invasion of human cytotrophoblasts. The Journal of Cell Biology 113:437–449.
   PubMed Web of Science ®Google Scholar
• Lou Y, Wu C, Wu M, Xie C, Ren L. 2014. The changes of neutrophil gelatinase-associated lipocalin in plasma and its expression in adipose tissue in pregnant women with gestational diabetes. Diabetes Research and Clinical Practice 104:136–142.
   PubMed Web of Science ®Google Scholar
• Lubetzky R, Mandel D, Mimouni FB, Herman L, Reich R, Reif S, et al. 2010. MMP-2 and MMP-9 and their tissue inhibitor in preterm human milk. Journal of Pediatric Gastroenterology and Nutrition 51:210.
   PubMed Web of Science ®Google Scholar
• Makris K, Rizos D, Kafkas N, Haliassos A. 2012. Neurophil gelatinase associated lipocalin as a new biomarker in laboratory medicine. Clinical Chemistry and Laboratory Medicine 50:1519–1532.
   PubMed Web of Science ®Google Scholar
• Pettitt DJ, Bennett PH, Saad MF, Charles MA, Nelson RG, Knowler WC, et al. 1991. Abnormal glucose tolerance during pregnancy in Pima Indian women. Long-term effects on offspring. Diabetes 40(2):126–130.
   PubMed Web of Science ®Google Scholar
• Stamenkovic I. 2003. Extracellular matrix remodelling: the role of matrix metalloproteinases. The Journal of Pathology 200:448–464.
   PubMed Web of Science ®Google Scholar
• Stepan H, Philipp A, Reiche M, Klostermann K, Schrey S, Reisenbüchler C, et al. 2010. Serum levels of the adipokine lipocalin-2 are increased in preeclampsia. Journal of Endocrinological Investigation 33:629–632.
   PubMed Web of Science ®Google Scholar
• Stojanovic N, Lewandowski K, Salata I, Bienkiewicz M, Tuck S, Prelevic G, et al. 2010. Serum levels of matrix metalloproteinases MMP-2 and MMP-9 and their inhibitors in women with glucose intolerance in pregnancy and normal controls. Gynecological Endocrinology 26:201–207.
   PubMed Web of Science ®Google Scholar
• Tam WH, Ma RCW, Ozaki R, Li AM, Chan MHM, Yuen LY, et al. 2017. In utero exposure to maternal hyperglycemia increases childhood cardiometabolic risk in offspring. Diabetes Care 40:679.
   PubMed Web of Science ®Google Scholar
• Wender-Ozegowska E, Michałowska-Wender G, Zawiejska A, Pietryga M, Brazert J, Wender M, et al. 2008. Concentration of chemokines in peripheral blood in first trimester of diabetic pregnancy. Acta Obstetricia et Gynecologica Scandinavica 87:14–19.
   PubMed Web of Science ®Google Scholar
• Wenyi Q, Zhang K, Kliethermes B, Ruhlen RL, Browne EP, Arcaro KF, Sauter ER. 2012. Differential expression of cancer associated proteins in breast milk based on age at first full term pregnancy. BMC Cancer 12:100.
   PubMed Web of Science ®Google Scholar
• Xu SY, Carlson M, Engström A, Garcia R, Peterson CG, Venge P. 1994. Purification and characterization of a human neutrophil lipocalin (HNL) from the secondary granules of human neutrophils. Scandinavian Journal of Clinical and Laboratory Investigation 54:36–76.
   Web of Science ®Google Scholar