References
- Abraham SK, Stopper H. (2004). Anti-genotoxicity of coffee against N-methyl-N-nitro-N-nitrosoguanidine in mouse lymphoma cells. Mutat Res 561:23–33
- Bøyum A. (1976). Isolation of lymphocytes, granulocytes and macrophages. Scand J Immunol 5:9–15
- Bravo J, Arbillaga L, de Peña MP, Cid C. (2013). Antioxidant and genoprotective effects of spent coffee extracts in human cells. Food Chem Toxicol 60:397–403
- Christensen R, Kristensen PK, Bartels EM, et al. (2007). Efficacy and safety of the weight-loss drug rimonabant: a meta-analysis of randomised trials. Lancet 370:1706–1713
- da Silva CJ, dos Santos JE, Takahashi CS. (2010). An evaluation of the genotoxic and cytotoxic effects of the anti-obesity drugs sibutramine and fenproporex. Hum Exp Toxicol 29:187–197
- Devasagayam TPA, Kamat JP, Mohan H, Kesavan PC. (1996). Caffeine as an antioxidant: inhibition of lipid peroxidation induced by reactive oxygen species. Biochim Biophys Acta 1282:63–70
- Drew BS. (2007). Obesity management: update on orlistat. Vasc Health Risk Manag 3:817–821
- Faust F, Kassie F, Knasmüller S, et al. (2004). The use of the alkaline comet assay with lymphocytes in human biomonitoring studies. Mutat Res 566:209–229
- Filippatos TD, Derdemezis CS, Gazi IF, et al. (2008). Orlistat-associated adverse effects and drug interactions: a critical review. Drug Saf 31:53–65
- Fujiwara J, Sowa Y, Horinaka M, et al. (2012). The anti-obesity drug orlistat promotes sensitivity to TRAIL by two different pathways in hormone-refractory prostate cancer cells. Int J Oncol 40:1483–1491
- Geriyol P, Basavanneppa HH, Dhananjaya BL. (2015). Protecting effect of caffeine against vinblastine (an anticancer drug) induced genotoxicity in mice. Drug Chem Toxicol 38:188–195
- Guzmán CD, García HE, Jacobo JA, et al. (2011). Effect of orlistat on lipid peroxidation, Na+, K + ATPase, glutathione and serotonin in rat brain. Proc West Pharmacol Soc 54:73–77
- Heck AM, Yanovski JA, Calis KA. (2000). Orlistat, a new lipase inhibitor for the management of obesity. Pharmacotherapy 20:270–279
- James WPT, Caterson ID, Coutinho W, et al. (2010). Effect of sibutramine on cardiovascular outcomes in overweight and obese subjects. N Engl J Med 363:905–917
- Kang JG, Park CY. (2012). Anti-obesity drugs: a review about their effects and safety. Diabetes Metab J 36:13–25
- Kazmi SAJ, Khan M, Mashori GR, et al. (2009). Influence of sibutramine, orlistat and Ispaghula in reducing body weight and total body fat content in obese individuals. J Ayub Med Coll Abbottabad 21:45–48
- Li MF, Cheung BM. (2011). Rise and fall of anti-obesity drugs. World J Diabetes 2:19–23
- Lin K-H, Yang Y-Y, Yang C-M, et al. (2013). Antioxidant activity of herbaceous plant extracts protect against hydrogen peroxide-induced DNA damage in human lymphocytes. BMC Res Notes 6:10–11
- Manning S, Pucci A, Finer N. (2014). Pharmacotherapy for obesity: novel agents and paradigms. Ther Adv Chronic Dis 5:135–148
- Møller P. (2004). Genotoxicity of environmental agents assessed by the alkaline comet assay. Basic Clin Pharmacol Toxicol 96:1–42
- OECD. (2010). In vitro mammalian cell micronucleus test. OECD guideline for the testing of chemicals. Test guideline no. 487. Paris, France
- Ohara T, Muroyama K, Yamamoto Y, Murosaki S. (2015). A combination of glucosyl hesperidin and caffeine exhibits an anti-obesity effect by inhibition of hepatic lipogenesis in mice. Phytother Res 29:310–316
- Orsolin PC, Silva-Oliveira RG, Nepomuceno JC. (2012). Assessment of the mutagenic, recombinagenic and carcinogenic potential of orlistat in somatic cells of Drosophila melanogaster. Food Chem Toxicol 50:2598–2604
- Pendleton M, Brown S, Thomas CM, Odle B. (2013). Potential toxicity of caffeine when used as a dietary supplement for weight loss. J Diet Suppl 10:1–5
- Rodgers RJ, Tschöp MH, Wilding JP. (2012). Anti-obesity drugs: past, present and future. Dis Model Mech 5:621–626
- Sabisz M, Skladanowski A. (2008). Modulation of cellular response to anticancer treatment by caffeine: inhibition of cell cycle checkpoints, DNA repair and more. Curr Pharm Biotechnol 9:325–336
- Sen S, Agarwal K, Mukherjee A, Sharma A. (1994). Potentiation by caffeine of the frequencies of chromosomal aberrations induced by chronic exposure to fenfluramine in mice. Drug Chem Toxicol 17:113–124
- Sinha S, Jothiramajayam M, Ghosh M, Mukherjee A. (2014). Evaluation of toxicity of essential oils palmarosa, citronella, lemongrass and vetiver in human lymphocytes. Food Chem Toxicol 68:71–77
- Tennant JR. (1964). Evaluation of the trypan blue technique for determination of cell viability. Transplantation 2:685–694
- Tice RR, Agurell E, Anderson D, et al. (2000). Single cell gel/comet assay: guidelines for in vitro and in vivo genetic toxicology testing. Environ Mol Mutagen 35:206–221
- World Health Organization. (2016). Obesity and overweight [Online]. Available from: http://www.who.int/mediacentre/factsheets/fs311/en/index.html
- Zheng G, Sayama K, Okubo T, et al. (2004). Anti-obesity effects of three major components of green tea, catechins, caffeine and theanine, in mice. In Vivo 18:55–62