Standardized aqueous stem bark extract of Gmelina arborea roxb. possesses nephroprotection against adriamycin-induced nephrotoxicity in Wistar rats

References

• Ajith, T.A., Aswathy, M.S., and Hema, U., 2008. Protective effect of Zingiber officinale Roscoe against anticancer drug doxorubicin-induced acute nephrotoxicity. Food and Chemical Toxicology, 46 (9), 3178–3181.
   PubMed Web of Science ®Google Scholar
• Aksun, S.A., et al., 2004. Beta2-microglobulin and cystatin C in type 2 diabetes: assessment of diabetic nephropathy. Experimental and Clinical Endocrinology and Diabetes. 12 (4), 195–200.
   Web of Science ®Google Scholar
• Al-Attar, A.M., Alrobai, A.A., and Almalki, D.A., 2017. Protective effect of olive and juniper leaves extracts on nephrotoxicity induced by thioacetamide in male mice. Saudi Journal of Biological Sciences, 24 (1), 15–22.
   PubMed Web of Science ®Google Scholar
• Allam, A.M.T., et al., 2015. Ameliorative potential of quercetin and berberine on experimentally induced nephrotoxicity in rats. Al-Azhar Assiut Medical Journal, 13 (4), 1–10.
   Google Scholar
• Al-Naimi, M.S., et al., 2019. Nephrotoxicity: Role and significance of renal biomarkers in the early detection of acute renal injury. Journal of Advanced Pharmaceutical Technology & Research, 10 (3), 95–99.
   PubMed Web of Science ®Google Scholar
• Amarasiri, A.M.S.S., et al., 2018. Acute nephroprotective and antioxidant activities of aqueous leaf extract of Plectranthus amboinicus (Roxb.) grown in Sri Lanka. Journal of Pharmacognosy and Phytochemistry, 7 (4), 155–161.
   Google Scholar
• Association of Analytical Communities (AOAC) 2000. 999.10, 999.11
   Google Scholar
• Attanayake, A.P., et al., 2015. Antioxidant activity of Gmelina arborea Roxb. (Verbenaceae) bark extract: In vivo and in vitro study. Journal of Medical Nutrition and Nutraceuticals, 4 (1), 32–38.
   Google Scholar
• Ayla, S., et al., 2011. Doxorubicin induced nephrotoxicity: protective effect of nicotinamide. International Journal of Cell Biology, 2011, 390238.
   PubMedGoogle Scholar
• Ayurveda Pharmacopoeia 1985. Department of Ayurveda, Colombo, Sri Lanka.
   Google Scholar
• Bartels, H., Böhmer, M., and Heierli, C., 1972. Serum creatinine determination without protein precipitation. Clinica Chimica Acta, 37, 193–197.
   PubMed Web of Science ®Google Scholar
• Bartholomew, R.J., and Delaney, A., 1964. Spectrophotometric studies and analytical application of the protein error of some pH indicators. Proceedings of the Australian Association of Clinical Biochemists, 1:64.
   Google Scholar
• Behairy, O.G., et al., 2017. Role of serum cystatin-C and beta-2 microglobulin as early markers of renal dysfunction in children with beta thalassemia major. International Journal of Nephrology and Renovascular Disease, 10, 261–268.
   PubMed Web of Science ®Google Scholar
• Benzer, F., et al., 2018. Chemoprotective effects of curcumin on doxorubicin-induced nephrotoxicity in wistar rats: by modulating inflammatory cytokines, apoptosis, oxidative stress and oxidative DNA damage. Archives of Physiology and Biochemistry, 124 (5), 448–457.
   PubMed Web of Science ®Google Scholar
• Blois, M., 1958. Antioxidant determinations by the use of a stable free radical. Nature, 181 (4617), 1199–1200.
   Web of Science ®Google Scholar
• Dhande, R.S., 2016. Folk medicinal therapy used in the treatment of renal calculi (kidney stone) in Maharashtra: A review. International Journal of Researches in Biosciences, Agriculture and Technology, 4 (3), 24–30.
   Google Scholar
• El-Sheikh, A.A.K., et al., 2012. Effect of coenzyme-Q10 on doxorubicin-Induced nephrotoxicity in rats. Advances in Pharmacological Sciences, 2012, 981461.
   PubMedGoogle Scholar
• Falah, S., Katayama, T., and Suzuki, T., 2008. Chemical constituents from Gmelina arborea bark and their antioxidant activity. Journal of Wood Science, 54 (6), 483–489.
   Web of Science ®Google Scholar
• Farnsworth, N.R., 1966. Biological and phytochemical screening of plants. Journal of Pharmaceutical Sciences, 55 (3), 225–276.
   PubMed Web of Science ®Google Scholar
• Heidari-Soreshjani, S., et al., 2017. Phytotherapy of nephrotoxicity-induced by cancer drugs: an updated review. Journal of Nephropathology, 6 (3), 254–263.
   PubMedGoogle Scholar
• Heravi, N.E., et al., 2018. Effect of Plantago major extract on doxorubicin-induced nephropathy in rat. Physiology and Pharmacology, 22, 269–278.
   Web of Science ®Google Scholar
• Ibrahim, K.M., et al., 2020. Protection from doxorubicin-induced nephrotoxicity by clindamycin: novel antioxidant, anti-inflammatory and anti-apoptotic roles. Naunyn-Schmiedeberg's Archives of Pharmacology, 393 (4), 739–748.
   PubMed Web of Science ®Google Scholar
• Insaf, A., and Raju, P.N., 2019. Potential of pure phytoconstituents and herbs in protection of drug induced nephrotoxicity. Indian Journal of Pharmaceutical Education and Research, 53 (3), 400–413.
   Web of Science ®Google Scholar
• Izzedine, H., and Perazella, M.A., 2017. Anticancer drug-induced acute kidney injury. Kidney International Reports, 2 (4), 504–514.
   PubMed Web of Science ®Google Scholar
• Jayaweera, D. M. A., 1982. Medicinal plants (indigenous and exotic) used in Ceylon. Sri Lanka: National Science Foundation in Sri Lanka.
   Google Scholar
• Kaur, S., Bedi, P.M.S., and Kaur, N., 2018. Anti-inflammatory effect of methanolic extract of Gmelina arborea bark and its fractions against carrageenan induced paw oedema in rats. Natural Product Research, 32 (23), 2861–2864.
   PubMed Web of Science ®Google Scholar
• Khajavi-Rad, A., Mohebbati, R., and Hosseinian, S., 2017. Drug-induced nephrotoxicity and medicinal plants. Iranian Journal of Kidney Diseases, 11 (3), 169–179.
   PubMed Web of Science ®Google Scholar
• Lawrence, L., et al., 2016. In vitro and in vivo antioxidant potential of Gmelina arborea stem bark. Journal of Chemical and Pharmaceutical Research, 8 (6), 167–172.
   Google Scholar
• Mohammadi, A., and Ahmadizadeh, M., 2018. Effects of antioxidants on xenobiotics-induced nephrotoxicity. Journal of Renal Injury Prevention, 7 (2), 56–57.
   Web of Science ®Google Scholar
• Mohebbati, R., et al., 2016. Adriamycin-induced oxidative stress is prevented by mixed hydro-alcoholic extract of Nigella sativa and Curcuma longa in rat kidney. Avicenna Journal of Phytomedicine, 6 (1), 86–94.
   PubMed Web of Science ®Google Scholar
• Molehin, O.R., 2020. Alleviation of doxorubicin-induced nephrotoxicity by Clerodendrum volubile leaf extract in Wistar rats: A preliminary study. Journal of Herbmed Pharmacology, 9 (2), 138–144.
   Google Scholar
• Oddoze, C., et al., 2001. Cystatin C is not more sensitive than creatinine for detecting early renal impairment in patients with diabetes. American Journal of Kidney Diseases, 38 (2), 310–316.
   PubMed Web of Science ®Google Scholar
• Ou, B., Hampsch-Woodill, M., and Prior, R.L., 2001. Development and validation of an improved oxygen radical absorbance capacity assay using fluorescein as the fluorescent probe. Journal of Agricultural and Food Chemistry, 49 (10), 4619–4626.
   PubMed Web of Science ®Google Scholar
• Pathala, D., Harini, A., and Hegde, P.L., 2015. A review on Gambhari (Gmelina arborea Roxb.). Journal of Pharmacognosy and Phytochemistry, 4 (2), 127–132.
   Google Scholar
• Principal, G.S., et al., 2010. New advances in molecular mechanisms and the prevention of adriamycin toxicity by antioxidant nutrients. Food and Chemical Toxicology, 48 (6), 1425–1438.
   PubMed Web of Science ®Google Scholar
• Prša, P., et al., 2020. The potential use of natural products to negate hepatic, renal and neuronal toxicity induced by cancer therapeutics. Biochemical Pharmacology, 173, 113551.
   PubMed Web of Science ®Google Scholar
• Raza, Z., and Naureen, Z., 2020. Melatonin ameliorates the drug induced nephrotoxicity: Molecular insights. Nefrologia : publicacion Oficial de la Sociedad Espanola Nefrologia, 40 (1), 12–25.
   PubMed Web of Science ®Google Scholar
• Re, R., et al., 1999. Antioxidant activity applying an improved ABTS radical cation decolorization assay. Free Radical Biology and Medicine, 26 (9-10), 1231–1237.
   PubMed Web of Science ®Google Scholar
• Rohit, K., Manodeep, C., and Jag, K., 2012. Phytochemical and pharmacological profile of Gmelina arborea: An overview. International Research Journal of Pharmacy, 3 (2), 61–64.
   Google Scholar
• Sampson, E.J., et al., 1980. A coupled- enzyme equilibrium method for measuring urea in serum: optimization and evaluation of the AACC study group on urea candidate reference method. Clinical Chemistry, 26 (7), 816–826.
   PubMed Web of Science ®Google Scholar
• Shahbazi, F., et al., 2020. Potential nephroprotective effects of resveratrol in drug induced nephrotoxicity: a narrative review of safety and efficacy data. Advances in Traditional Medicine. doi:https://doi.org/10.1007/s13596-020-00432-y
   Google Scholar
• Sharma, V., et al., 2015. Standardization and antioxidant activity of an Ayurvedic formulation “Kushavleha. International Journal of Green Pharmacy, 9 (4), S55–S62.
   Google Scholar
• Siddhuraju, P., and Becker, K., 2003. Antioxidant properties of various solvent extracts of total phenolic constituents from three different agroclimatic origins of drumstick tree (Moringa oleifera Lam.) leaves. Journal of Agricultural and Food Chemistry, 51 (8), 2144–2155.
   PubMed Web of Science ®Google Scholar
• Singleton, V.L., Orthofer, R., and Lamuela-Raventos, R.M., 1999. Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin- Ciocaltue reagent. Methods in Enzymology, 299, 152–178.
   Web of Science ®Google Scholar
• Sreejith, G., et al., 2014. Hepatoprotective activity of Oxalis corniculata L. ethanolic extract against paracetamol induced hepatotoxicity in Wistar rats and its in vitro antioxidant effects. Indian Journal of Experimental Biology, 52 (2), 147–152.
   PubMed Web of Science ®Google Scholar
• Sri Lanka Standard (SLS) 1973. 242: Bureau of Ceylon Standards.
   Google Scholar
• Sri Lanka Standard (SLS) 1982. 516, Part 3 Bureau of Ceylon Standards.
   Google Scholar
• Sri Lanka Standard (SLS) 1992. 516, Part 6 Bureau of Ceylon Standards.
   Google Scholar
• Watanabe, N., et al., 1986. Urinary protein as measured with a pyrogallol red-molybdate complex, manually and in a Hitachi 726 automated analyzer. Clinical Chemistry, 32 (8), 1551–1554.
   PubMed Web of Science ®Google Scholar
• Weichselbaum, T.E., 1946. An accurate and rapid method for the determination of proteins in small amounts of blood serum and plasma. American Journal of Clinical Pathology, 10, 40–49.
   PubMedGoogle Scholar
• WHO 2007. WHO guidelines for assessing quality of herbal medicines with reference to contaminants and residues. Geneva: World Health Organization.
   Google Scholar
• Xiao, Y., et al., 2013. The effect of Chinese herbal medicine on albuminuria levels in patients with diabetic nephropathy: A systematic review and meta-analysis. Evidence-Based Complementary and Alternative Medicine: Ecam, 2013, 937549.
   PubMed Web of Science ®Google Scholar
• Yagmurca, M., Yasar, Z., and Bas, O., 2015. Effects of quercetin on kidney injury induced by doxorubicin. Bratisl Lek Listy, 116 (8), 486–489.
   PubMed Web of Science ®Google Scholar