References
- Ahmed, K., et al., 2012. Nanoemulsion- and emulsion-based delivery systems for curcumin: encapsulation and release properties. Food Chemistry, 132 (2), 799–807.
- Ahn, S., Costa, J., and Emanuel, J., 1996. PicoGreen quantitation of DNA: effective evaluation of samples pre- or post-PCR. Nucleic Acids Research, 24 (13), 2623–2625.
- Armağan, H.H. and Nazıroğlu, M., 2021. Curcumin attenuates hypoxia-induced oxidative neurotoxicity, apoptosis, calcium, and zinc ion influxes in a neuronal cell line: involvement of TRPM2 channel. Neurotoxicity Research, 39 (3), 618–633.
- Ayati, Z., et al., 2019. Ethnobotany, phytochemistry and traditional uses of Curcuma spp. and pharmacological profile of two important species (C. longa and C. zedoaria): a review. Current Pharmaceutical Design, 25 (8), 871–935.
- Azami, S.J., et al., 2018. Curcumin nanoemulsion as a novel chemical for the treatment of acute and chronic toxoplasmosis in mice. International Journal of Nanomedicine, 13, 7363–7374.
- Bagheri, H., et al., 2020. Effects of curcumin on mitochondria in neurodegenerative diseases. BioFactors, 46 (1), 5–20.
- Bala, K., Tripathy, B.C., and Sharma, D., 2006. Neuroprotective and anti-ageing effects of curcumin in aged rat brain regions. Biogerontology, 7 (2), 81–89.
- Balaji, S. and Chempakam, B., 2010. Toxicity prediction of compounds from turmeric (Curcuma longa L). Food and Chemical Toxicology, 48 (10), 2951–2959.
- Barzegar, A. and Moosavi-Movahedi, A.A., 2011. Intracellular ROS protection efficiency and free radical-scavenging activity of curcumin. PLoS One, 6 (10), e26012.
- Bhat, A., et al., 2019. Benefits of curcumin in brain disorders. BioFactors, 45 (5), 666–689.
- Camacho-Barquero, L., et al., 2007. Curcumin, a Curcuma longa constituent, acts on MAPK p38 pathway modulating COX-2 and iNOS expression in chronic experimental colitis. International Immunopharmacology, 7 (3), 333–342.
- Choi, W., et al., 2012. The regulatory effect of veratric acid on NO production in LPS-stimulated RAW264.7 macrophage cells. Cellular Immunology, 280 (2), 164–170.
- Copetti, P.M., et al., 2020. Development, characterisation, stability study and antileukemic evaluation of nanoemulsions containing Astrocaryum aculeatum extract. Natural Product Research, 1–6.
- Costa, F., et al., 2012. Influence of Val16Ala SOD2 polymorphism on the in-vitro effect of clomiphene citrate in oxidative metabolism. Reproductive Biomedicine Online, 24 (4), 474–481.
- da Costa, I.M., et al., 2019. Supplementation with Curcuma longa reverses neurotoxic and behavioral damage in models of Alzheimer’s disease: a systematic review. Current Neuropharmacology, 17 (5), 406–421.
- Dalcin, A.J.F., et al., 2019. Nanoencapsulation of the flavonoid dihydromyricetin protects against the genotoxicity and cytotoxicity induced by cationic nanocapsules. Colloids and Surfaces. B, Biointerfaces, 173, 798–805.
- Del Prado-Audelo, M.L., et al., 2019. Formulations of curcumin nanoparticles for brain diseases. Biomolecules, 9 (2), 56–28.
- Eisenbrand, G., et al., 2002. Methods of in vitro toxicology. Food and Chemical Toxicology, 40 (2–3), 193–236.
- Fan, C., et al., 2018. Neuroprotective effects of curcumin on IL-1β-induced neuronal apoptosis and depression-like behaviors caused by chronic stress in rats. Frontiers in Cellular Neuroscience, 12, 516–517.
- Fujisawa, S., et al., 2004. Cytotoxicity, ROS-generation activity and radical-scavenging activity of curcumin and related compounds. Anticancer Research, 24 (2B), 563–569.
- Fukui, M., Choi, H.J., and Zhu, B.T., 2010. Mechanism for the protective effect of resveratrol against oxidative stress-induced neuronal death. Free Radical Biology & Medicine, 49 (5), 800–813.
- Gartlon, J., et al., 2006. Evaluation of a proposed in vitro test strategy using neuronal and non-neuronal cell systems for detecting neurotoxicity. Toxicology in Vitro, 20 (8), 1569–1581.
- Ghasemi, F., et al., 2019. Effects of curcumin on microglial cells. Neurotoxicity Research, 36 (1), 12–26.
- Gündel, S., et al., 2019. Evaluation of cytotoxicity, genotoxicity and ecotoxicity of nanoemulsions containing Mancozeb and Eugenol. Ecotoxicology and Environmental Safety, 169, 207–215.
- Gündel, S.S., et al., 2018. Basil oil-nanoemulsions: development, cytotoxicity and evaluation of antioxidant and antimicrobial potential. Journal of Drug Delivery Science and Technology, 46, 378–383.
- Hewlings, S. and Kalman, D., 2017. Curcumin: a review of its effects on human health. Foods, 6 (10), 92.
- Jaguezeski, A.M., et al., 2019. Low-dose curcumin-loaded Eudragit L-100-nanocapsules in the diet of dairy sheep increases antioxidant levels and reduces lipid peroxidation in milk. Journal of Food Biochemistry, 43 (8), 1–14.
- Khan, M.S., et al., 2019. Dietary supplementation of the antioxidant curcumin halts systemic LPS-induced neuroinflammation-associated neurodegeneration and memory/synaptic impairment via the JNK/NF-κB/Akt signaling pathway in adult rats. Oxidative Medicine and Cellular Longevity, 2019, 1–23.
- Khazdair, M.R., et al., 2019. Neuroprotective potency of some spice herbs, a literature review. Journal of Traditional and Complementary Medicine, 9 (2), 98–105.
- Kunwar, A., et al., 2008. Quantitative cellular uptake, localization and cytotoxicity of curcumin in normal and tumor cells. Biochimica et Biophysica Acta, 1780 (4), 673–679.
- Liczbiński, P., Michałowicz, J., and Bukowska, B., 2020. Molecular mechanism of curcumin action in signaling pathways: review of the latest research. Phytotherapy Research, 34 (8), 1992–2005.
- Maiti, P. and Dunbar, G., 2018. Use of curcumin, a natural polyphenol for targeting molecular pathways in treating age-related neurodegenerative diseases. International Journal of Molecular Sciences, 19 (6), 1637.
- Mendonça, L.M., et al., 2009. Evaluation of the cytotoxicity and genotoxicity of curcumin in PC12 cells. Mutation Research, 675 (1–2), 29–34.
- Mursaleen, L., Somavarapu, S., and Zariwala, M.G., 2020. Deferoxamine and curcumin loaded nanocarriers protect against rotenone-induced neurotoxicity. Journal of Parkinson’s Disease, 10 (1), 99–111.
- Nakamae, I., et al., 2019. Curcumin derivatives verify the essentiality of ROS upregulation in tumor suppression. Molecules, 24 (22), 4067–4025.
- Namgyal, D., et al., 2020. The neuroprotective effect of curcumin against Cd-induced neurotoxicity and hippocampal neurogenesis promotion through CREB-BDNF signaling pathway. Toxicology, 442, 152542.
- Parasuraman, S., 2011. Toxicological screening. Journal of Pharmacology & Pharmacotherapeutics, 2 (2), 74–79.
- Qureshi, S., Shah, A.H., and Ageel, A.M., 1992. Toxicity studies on Alpinia galanga and Curcuma longa. Planta Medica, 58 (2), 124–127.
- Rakotoarisoa, M. and Angelova, A., 2018. Amphiphilic nanocarrier systems for curcumin delivery in neurodegenerative disorders. Medicines, 5 (4), 126.
- Sadegh Malvajerd, S., et al., 2019. Brain delivery of curcumin using solid lipid nanoparticles and nanostructured lipid carriers: preparation, optimization, and pharmacokinetic evaluation. ACS Chemical Neuroscience, 10 (1), 728–739.
- Soleimani, V., Sahebkar, A., and Hosseinzadeh, H., 2018. Turmeric (Curcuma longa) and its major constituent (curcumin) as nontoxic and safe substances: review. Phytotherapy Research, 32 (6), 985–995.
- Syng-Ai, C., Kumari, A.L., and Khar, A., 2004. Effect of curcumin on normal and tumor cells: role of glutathione and bcl-2. Molecular Cancer Therapeutics, 3 (9), 1101–1108.
- Tomeh, M.A., Hadianamrei, R., and Zhao, X., 2019. A review of curcumin and its derivatives as anticancer agents. International Journal of Molecular Sciences, 20 (5), 1033.
- Umerska, A., et al., 2018. Polymeric nanoparticles for increasing oral bioavailability of Curcumin. Antioxidants, 7 (4), 46.
- Vaiserman, A., Koliada, A., and Lushchak, O., 2020. Neuroinflammation in pathogenesis of Alzheimer’s disease: phytochemicals as potential therapeutics. Mechanisms of Ageing and Development, 189, 111259.
- Wang, Z., et al., 2020. A curcumin derivative activates TFEB and protects against parkinsonian neurotoxicity in vitro. International Journal of Molecular Sciences, 21 (4), 1515.
- Wei, W., et al., 2021. Dichloroacetic acid-induced dysfunction in rat hippocampus and the protective effect of curcumin. Metabolic Brain Disease, 36 (4), 545–556.
- Willenbacher, E., et al., 2019. Curcumin: new insights into an ancient ingredient against cancer. International Journal of Molecular Sciences, 20 (8), 1808–1813.
- Xiang, B., et al., 2021. Curcumin ameliorates copper-induced neurotoxicity through inhibiting oxidative stress and mitochondrial apoptosis in SH-SY5Y cells. Neurochemical Research, 46 (2), 367–378.
- Zaki, S.M., et al., 2020. Nano-curcumin versus curcumin in amelioration of deltamethrin-induced hippocampal damage. Histochemistry and Cell Biology, 154 (2), 157–175.
- Zhang, J., et al., 2019. Curcumin inhibits LPS-induced neuroinflammation by promoting microglial M2 polarization via TREM2/ TLR4/ NF-κB pathways in BV2 cells. Molecular Immunology, 116, 29–37.
- Zielińska, A., et al., 2020. Polymeric nanoparticles: production, characterization, toxicology and ecotoxicology. Molecules, 25 (16), 3731.