References
- Akiyoshi, R., et al., 2018. Microglia enhance synapse activity to promote local network synchronization. eNeuro, 5 (5), ENEURO.0088-18.2018–13.
- Block, M.L., Zecca, L., and Hong, J.S., 2007. Microglia-mediated neurotoxicity: uncovering the molecular mechanisms. Nature Reviews. Neuroscience, 8 (1), 57–69.
- Chan, X.H.S., et al., 2020. Factors affecting the electrocardiographic QT interval in malaria: a systematic review and meta-analysis of individual patient data. PLoS Medicine, 17 (3), e1003040–20.
- He, S., et al., 2020. HERG channel and cancer: a mechanistic review of carcinogenic processes and therapeutic potential. Biochimica et Biophysica Acta. Reviews on Cancer, 1873 (2), 188355.
- Heal, D.J., et al., 2013. Amphetamine, past and present-a pharmacological and clinical perspective. Journal of Psychopharmacology (Oxford, England), 27 (6), 479–496.
- Heindl, S., et al., 2018. Automated morphological analysis of microglia after stroke. Frontiers in Cellular Neuroscience, 12 (106), 106–111.
- Hill, S.L., et al., 2011. Clinical toxicology of newer recreational drugs. Journal: Clinica.
- Hollister, L.E. and Gillespie, H.K., 1970. A new stimulant, prolintane hydrochloride, compared with dextroamphetamine in fatigued volunteers. The Journal of Clinical Pharmacology and the Journal of New Drugs, 10 (2), 103–109.
- Huang, X.P., et al., 2010. Identification of human Ether-à-go-go related gene modulators by three screening platforms in an academic drug-discovery setting. Assay and Drug Development Technologies, 8 (6), 727–742.
- Hughes, R. N., 2004. The value of spontaneous alternation behavior (SAB) as a test of retention in pharmacological investigations of memory. Neuroscience and Biobehavioral Reviews, 28, 497–505.
- International Conference on Harmonization (ICH), 1997. Timing of non-clinical safety studies for the conduct of human clinical trials for pharmaceuticals. Geneva: International Conference on Harmonization. Available from: https://www.pmda.go.jp/files/000156313.pdf [Accessed 2 May 2021].
- Ito, D., et al., 1998. Microglia-specific localisation of a novel calcium binding protein, Iba1. Brain Research. Molecular Brain Research, 57 (1), 1–9.
- Irwin S., 1968. Comprehensive observational assessment:1a. A systematic quantitative procedure for assessing the behavioural and physiologicstate of the mouse. Psychopharmacologia, Berlin, 13, 222–257.
- Ke, Y., and Solaro, R. J., 2008. Use of a decoy peptide to purify p21 activated kinase-1 in cardiac muscle and identification of ceramide-related activation. Biologics, 2, 903–909.
- Kirsch, G.E., et al., 2004. Variability in the measurement of hERG potassium channel inhibition: effects of temperature and stimulus pattern. Journal of Pharmacological and Toxicological Methods, 50 (2), 93–101.
- Kyle, P.B. and Daley, W.P., 2007. Domestic abuse of the European rave drug prolintane. Journal of Analytical Toxicology, 31 (7), 415–418.
- Larsen, K.E., et al., 2002. Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis. The Journal of Neuroscience : The Official Journal of the Society for Neuroscience, 22 (20), 8951–8960.
- Lee, H.B. and Blaufox, M.D., 1985. Blood volume in the rat. Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine, 26 (1), 72–76.
- Lee, S., et al., 2016. Evaluation of nefazodone-induced cardiotoxicity in human induced pluripotent stem cell-derived cardiomyocytes. Toxicology and Applied Pharmacology, 296, 42–53.
- Martinez-mir, et al., 1997. Prolintane: a “masked” amphetamine. Annals of Pharmacotherapy, 31, 256.
- Ministry of Health, Labor and Welfare (MHLW), 2015. Minutes of the drug department designated by Pharmacists and Food Sanitation Council. Tokyo: Chemicals Investigation Promoting Council. Available from: https://www.mhlw.go.jp/stf/shingi2/0000110684.html [Accessed 1 May 2021].
- Miyamoto, A., et al., 2016. Microglia contact induces synapse formation in developing somatosensory cortex. Nature Communications, 7 (1), 12540–12512.
- National Research Council 2011. Guide for the care and use of laboratory animals. 8th ed. Washington: National Academies Press.
- Parkhurst, C.N., et al., 2013. Microglia promote learning-dependent synapse formation through brain-derived neurotrophic factor. Cell, 155 (7), 1596–1609.
- Redfern, W.S., et al., 2003. Relationships between preclinical cardiac electrophysiology, clinical QT interval prolongation and torsade de pointes for a broad range of drugs: evidence for a provisional safety margin in drug development. Cardiovascular Research, 58 (1), 32–45.
- Ruth, J.A., Ullman, E.A., and Collins, A.C., 1988. An analysis of cocaine effects on locomotor activities and heart rate in four inbred mouse strains. Pharmacology Biochemistry and Behavior, 29 (1), 157–162.
- Sectioning 2020. Histological methods for CNS. Available from: https://pathologycenter.jp/method-e/method10-1.html [Accessed 5 December 2020].
- Shin, W.H., Kim, K.S., and Kim, E.J., 2006. Electrophysiological effects of brompheniramine on cardiac ion channels and action potential. Pharmacological Research, 54 (6), 414–420.
- Sofuoglu, M. and Sewell, R.A., 2009. Norepinephrine and stimulant addiction. Addiction Biology, 14 (2), 119–129.
- Stahl, S. M., 2020. Prescriber’s guide: Stahl’s essential psychopharmacology. Cambridge: Cambridge University Press.
- Tamijani, S.M.S., et al., 2018. Effect of three different regimens of repeated methamphetamine on rats’ cognitive performance. Cognitive Processing, 19 (1), 107–115.
- United Nations Office on Drugs and Crime (UNODC), 2017. Global synthetic drugs assessment: amphetamine-type stimulants and new psychoactive substances. UNODC Research. Vienna: UNDOC. Available from: https://www.unodc.org. [Accessed 5 May 2021].
- United Nations Office on Drugs and Crime (UNODC), 2007. Commission on Narcotic Drugs. UNODC Research. Available from: https://www.unodc.org. [Accessed 5 May 2021].
- United Nations Office on Drugs and Crime (UNODC), 2020. World drug report, 2020. UNODC Research. Vienna: UNDOC. Available from: https://www.unodc.org. [Accessed 5 May 2021].
- Wolf, A., et al., 2016. A comprehensive behavioral test battery to assess learning and memory in 129S6/Tg2576 mice. PLoS One, 11 (1), e0147733–23.
- Yoon, K.S., et al., 2019. 2-(2,5-Dimethoxy-4-methylphenyl)-N-(2-methoxybenzyl)ethanamine (25D-NBOMe) and N-(2-methoxybenzyl)-2,5-dimethoxy-4-chlorophenethylamine (25C-NBOMe) induce adverse cardiac effects in vitro and in vivo. Toxicology Letters, 304, 50–57.
- Yun, J., et al., 2016. P21 (Cdc42/Rac)-activated kinase 1 (PAK1) is associated with cardiotoxicity induced by antihistamines. Archives of Pharmacal Research, 39 (12), 1644–1652.
- Yun, J.S. and Kim, S.Y., 2015. Antihistamines modulate the integrin signaling pathway in h9c2 rat cardiomyocytes: Possible association with cardiotoxicity. Human & Experimental Toxicology, 34 (8), 796–807.
- Zhao, X., et al., 2008. Arsenic trioxide-induced apoptosis in H9c2 cardiomyocytes: implications in cardiotoxicity. Basic & Clinical Pharmacology & Toxicology, 102 (5), 419–425.