Ameliorating effect of rutin against diclofenac-induced cardiac injury in rats with underlying function of FABP3, MYL3, and ANP

References

• Abdel-Daim, M.M., et al., 2018. Lycopene attenuates tulathromycin and diclofenac sodium-induced cardiotoxicity in mice. International Journal of Molecular Sciences, 19 (2), 344.
   PubMed Web of Science ®Google Scholar
• Abdulmajeed, N., et al., 2015. Amelioration of cardiotoxic impacts of diclofenac sodium by vitamin B complex. European Review for Medical and Pharmacological Sciences, 19, 671–681.
   PubMed Web of Science ®Google Scholar
• Alabi, Q.K., and Akomolafe, R., 2020. Kolaviron diminishes diclofenac-induced liver and kidney toxicity in Wistar rats via suppressing inflammatory events, upregulating antioxidant defenses, and improving hematological indices. Dose-Response: A Publication of International Hormesis Society, 18 (1), 1559325819899256.
   Web of Science ®Google Scholar
• Alonso-Castro, A.J., Domínguez, F., and García-Carrancá, A., 2013. Rutin exerts antitumor effects on nude mice bearing SW480 tumor. Archives of Medical Research, 44 (5), 346–351.
   PubMed Web of Science ®Google Scholar
• Arafa, M.H., Mohammad, N.S., and Atteia, H.H., 2020. Rho-kinase inhibitors ameliorate diclofenac-induced cardiotoxicity in chloroquine-treated adjuvant arthritic rats. Life Sciences, 254, 117605.
   PubMed Web of Science ®Google Scholar
• Arjumand, W., Seth, A., and Sultana, S., 2011. Rutin attenuates cisplatin induced renal inflammation and apoptosis by reducing NFκB, TNF-α and caspase-3 expression in Wistar rats. Food and Chemical Toxicology: An International Journal Published for the British Industrial Biological Research Association, 49 (9), 2013–2021.
   PubMed Web of Science ®Google Scholar
• Avila, A.M., et al., 2020. An FDA/CDER perspective on nonclinical testing strategies: classical toxicology approaches and new approach methodologies (NAMs). Regulatory Toxicology and Pharmacology: RTP, 114, 104662.
   PubMed Web of Science ®Google Scholar
• Awad, H.H., et al., 2021. Comparative study on beneficial effects of vitamins B and D in attenuating doxorubicin induced cardiotoxicity in rats: emphasis on calcium homeostasis. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 140, 111679.
   PubMed Web of Science ®Google Scholar
• Bhatt, S., et al., 2021. Glabridin attenuates paracetamol-induced liver injury in mice via CYP2E1-mediated inhibition of oxidative stress. Drug and Chemical Toxicology, 1–9. DOI:10.1080/01480545.2021.1945004
   Web of Science ®Google Scholar
• Chow, C.-W., et al., 2003. Oxidative stress and acute lung injury. American Journal of Respiratory Cell and Molecular Biology, 29 (4), 427–431.
   PubMed Web of Science ®Google Scholar
• Dogra, A., et al., 2020. Effect of rutin on pharmacokinetic modulation of diclofenac in rats. Xenobiotica; the Fate of Foreign Compounds in Biological Systems, 50 (11), 1332–1340.
   PubMed Web of Science ®Google Scholar
• Dogra, A., et al., 2021. Glabridin ameliorates methotrexate-induced liver injury via attenuation of oxidative stress, inflammation, and apoptosis. Life Sciences, 278, 119583.
   PubMed Web of Science ®Google Scholar
• Elsherif, N.A., Nasser, S.A., and Hussin, K.M., Effect of co-supplementation of vitamin C and E on diclofenac-induced renal injury in male albino mice. Journal of Academic Research, 308–329. http://lam.edu.ly/ar/images/acadj/issue8/15.pdf.
   Google Scholar
• Ferdinandy, P., et al., 2019. Definition of hidden drug cardiotoxicity: paradigm change in cardiac safety testing and its clinical implications. European Heart Journal, 40 (22), 1771–1777.
   PubMed Web of Science ®Google Scholar
• Ghosh, R., Alajbegovic, A., and Gomes, A.V., 2015. NSAIDs and cardiovascular diseases: role of reactive oxygen species. Oxidative Medicine and Cellular Longevity, 2015, 536962.
   PubMed Web of Science ®Google Scholar
• Gupta, A., et al., 2021. Antioxidant, anti-inflammatory and hepatoprotective activities of Terminalia bellirica and its bioactive component ellagic acid against diclofenac induced oxidative stress and hepatotoxicity. Toxicology Reports, 8, 44–52.
   PubMed Web of Science ®Google Scholar
• Hudson, M., et al., 2007. Risk of congestive heart failure with nonsteroidal antiinflammatory drugs and selective cyclooxygenase 2 inhibitors: a class effect? Arthritis and Rheumatism, 57 (3), 516–523.
   PubMed Web of Science ®Google Scholar
• Jin, H., et al., 2013. The role of sulfur dioxide in the regulation of mitochondrion-related cardiomyocyte apoptosis in rats with isopropylarterenol-induced myocardial injury. International Journal of Molecular Sciences, 14 (5), 10465–10482.
   PubMed Web of Science ®Google Scholar
• Kelleni, M. T., and Abdelbasset, M., 2018. Drug induced cardiotoxicity: mechanism, prevention and management. London: IntechOpen.
   Google Scholar
• Khafaga, A.F., and El-Sayed, Y.S., 2018. Spirulina ameliorates methotrexate hepatotoxicity via antioxidant, immune stimulation, and proinflammatory cytokines and apoptotic proteins modulation. Life Sciences, 196, 9–17.
   PubMed Web of Science ®Google Scholar
• Khan, R.A., Khan, M.R., and Sahreen, S., 2012. CCl 4-induced hepatotoxicity: protective effect of rutin on p53, CYP2E1 and the antioxidative status in rat. BMC Complementary and Alternative Medicine, 12 (1), 1–6.
   Web of Science ®Google Scholar
• Kim, G.E., and Kass, D.A., 2016. Cardiac phosphodiesterases and their modulation for treating heart disease. Heart Failure, 243, 249–269.
   Google Scholar
• Koc, K., et al., 2020. Gastroprotective effects of oleuropein and thymol on indomethacin-induced gastric ulcer in Sprague-Dawley rats. Drug and Chemical Toxicology, 43 (5), 441–453.
   PubMed Web of Science ®Google Scholar
• Korkut Celikates, B., et al., 2021. Effects of quetiapine administration on sperm quality and testicular histology. Drug and Chemical Toxicology, 1–9.
   PubMed Web of Science ®Google Scholar
• Lam, C.K., and Wu, J.C., 2021. Clinical trial in a dish: using patient-derived induced pluripotent stem cells to identify risks of drug-induced cardiotoxicity. Arteriosclerosis, Thrombosis, and Vascular Biology, 41 (3), 1019–1031.
   PubMed Web of Science ®Google Scholar
• Latimer, K. S., 2011. Duncan and Prasse's veterinary laboratory medicine: clinical pathology. Ames, Iowa, USA: John Wiley & Sons.
   Google Scholar
• Maity, T., et al., 2012. Hepatoprotective activity of Mikania scandens (L.) willd. against diclofenac sodium-induced liver toxicity in rats. Asian Journal of Pharmaceutical and Clinical Research, 5, 185–189.
   Google Scholar
• Martín Arias, L.H., et al., 2019. Cardiovascular risk of nonsteroidal anti-inflammatory drugs and classical and selective cyclooxygenase-2 inhibitors: a meta-analysis of observational studies. Journal of Clinical Pharmacology, 59 (1), 55–73.
   PubMed Web of Science ®Google Scholar
• Najenson, A.C., et al., 2018. Atrial natriuretic peptide reduces inflammation and enhances apoptosis in rat acute pancreatitis. Acta Physiologica, 222 (3), e12992.
   Web of Science ®Google Scholar
• Nishi, K., et al., 2018. Doxorubicin-induced female reproductive toxicity: an assessment of ovarian follicular apoptosis, cyclicity and reproductive tissue histology in Wistar rats. Drug and Chemical Toxicology, 41 (1), 72–81.
   PubMed Web of Science ®Google Scholar
• Oda, S.S., and Derbalah, A.E., 2018. Impact of diclofenac sodium on tilmicosin-induced acute cardiotoxicity in rats (tilmicosin and diclofenac cardiotoxicity). Cardiovascular Toxicology, 18 (1), 63–75.
   PubMed Web of Science ®Google Scholar
• Owumi, S.E., Aliyu‐Banjo, N.O., and Odunola, O.A., 2020. Selenium attenuates diclofenac-induced testicular and epididymal toxicity in rats. Andrologia, 52 (9), e13669.
   PubMed Web of Science ®Google Scholar
• Owumi, S.E., and Dim, U.J., 2019. Biochemical alterations in diclofenac-treated rats: effect of selenium on oxidative stress, inflammation, and hematological changes. Toxicology Research and Application, 3, 239784731987435.
   Google Scholar
• Prince, P.S.M., and Priya, S., 2010. Preventive effects of rutin on lysosomal enzymes in isoproterenol induced cardio toxic rats: biochemical, histological and in vitro evidences. European Journal of Pharmacology, 649 (1-3), 229–235.
   PubMed Web of Science ®Google Scholar
• Punithavathi, V., Shanmugapriya, K., and Prince, P.S.M., 2010. Protective effects of rutin on mitochondrial damage in isoproterenol-induced cardiotoxic rats: an in vivo and in vitro study. Cardiovascular Toxicology, 10 (3), 181–189.
   PubMed Web of Science ®Google Scholar
• Shah, A., et al., 2011. Oxidative stress augments the secretion of atrial natriuretic peptide in isolated rat atria. Peptides, 32 (6), 1172–1178.
   PubMed Web of Science ®Google Scholar
• Shingu, Y., et al., 2018. Decreased gene expression of fatty acid binding protein 3 in the atrium of patients with new onset of atrial fibrillation in cardiac perioperative phase. Journal of Cardiology, 71 (1), 65–70.
   PubMed Web of Science ®Google Scholar
• Song, G.X., et al., 2012. Overexpression of FABP3 promotes apoptosis through inducing mitochondrial impairment in embryonic cancer cells. Journal of Cellular Biochemistry, 113 (12), 3701–3708.
   PubMed Web of Science ®Google Scholar
• Spitz, S., 2013. Physicians should be cautious when prescribing diclofenac. CMAJ: Canadian Medical Association Journal = Journal de L'association Medicale Canadienne, 185 (6), 470–470.
   PubMed Web of Science ®Google Scholar
• Takahashi, A., et al., 2004. Oxidative stress-induced apoptosis is associated with alterations in mitochondrial caspase activity and Bcl-2-dependent alterations in mitochondrial pH (pHm). Brain Research Bulletin, 62 (6), 497–504.
   PubMed Web of Science ®Google Scholar
• Waksman, J.C., Brody, A., and Phillips, S.D., 2007. Nonselective nonsteroidal antiinflammatory drugs and cardiovascular risk: are they safe? The Annals of Pharmacotherapy, 41 (7), 1163–1173.
   PubMed Web of Science ®Google Scholar
• World Health Organization, 2021. Fact sheet for cardiovascular diseases (CVDs), 11th June, 2021. Available from: https://www.who.int/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds).
   Google Scholar
• Yoo, H., et al., 2014. Anti-inflammatory effects of rutin on HMGB1-induced inflammatory responses in vitro and in vivo. Inflammation Research, 63 (3), 197–206.
   PubMed Web of Science ®Google Scholar
• Zhang, S., et al., 2019. Protective effect of Shenmai injection on doxorubicin-induced cardiotoxicity via regulation of inflammatory mediators. BMC Complementary and Alternative Medicine, 19 (1), 1–10.
   PubMed Web of Science ®Google Scholar
• Zhang, X., et al., 2005. Apoptosis and cell proliferation in proliferative retinal disorders: PCNA, Ki-67, caspase-3, and PARP expression. Current Eye Research, 30 (5), 395–403.
   PubMed Web of Science ®Google Scholar