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Research Articles

Renal tubular response to titanium dioxide nanoparticles exposure

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Pages 1130-1137 | Received 23 May 2022, Accepted 30 Sep 2022, Published online: 18 Oct 2022

References

  • Abdou, K.H., et al., 2019. Moringa oleifera leaves extract protects titanium dioxide nanoparticles-induced nephrotoxicity via Nrf2/HO-1 signaling and amelioration of oxidative stress. Biological Trace Element Research, 187 (1), 181–191.
  • Baranowska-Wójcik, E., et al., 2020. Effects of titanium dioxide nanoparticles exposure on human health – a review. Biological Trace Element Research, 193 (1), 118–129.
  • Brand, W., et al., 2020. Possible effects of titanium dioxide particles on human liver, intestinal tissue, spleen and kidney after oral exposure. Nanotoxicology, 14 (7), 985–1007.
  • Bulacio, R.P., et al., 2015. Organic anion transporter 5 (Oat5) urinary excretion is a specific biomarker of kidney injury: evaluation of urinary excretion of exosomal Oat5 after N-acetylcysteine prevention of cisplatin induced nephrotoxicity. Chemical Research in Toxicology, 28 (8), 1595–1602.
  • Bulacio, R.P. and Torres, A.M., 2019. Caveolin-2 in urine as a novel biomarker of renal recovery after cisplatin induced nephrotoxicity in rats. Toxicology Letters, 313, 169–177.
  • Campagno, R.V., et al., 2018. Renal expression and urinary excretion of Na+/dicarboxylate cotransporter 1 (NaDC1) in obstructive nephropathy: a candidate biomarker for this pathology. Pflugers Archiv: European Journal of Physiology, 470 (12), 1777–1786.
  • Canli, E.G., Dogan, A., and Canli, M., 2018. Serum biomarker levels alter following nanoparticle (Al2O3, CuO, TiO2) exposures in freshwater fish (Oreochromis niloticus). Environmental Toxicology and Pharmacology, 62, 181–187.
  • Elgrabli, D., et al., 2015. Biodistribution and clearance of TiO2 nanoparticles in rats after intravenous injection. PLoS One, 10 (4), e0124490.
  • Fadoju, O., et al., 2019. Evaluation of cytogenotoxicity and oxidative stress parameters in male Swiss mice co-exposed to titanium dioxide and zinc oxide nanoparticles. Environmental Toxicology and Pharmacology, 70, 103204.
  • Geraets, L., et al., 2014. Tissue distribution and elimination after oral and intravenous administration of different titanium dioxide nanoparticles in rats. Particle and Fibre Toxicology, 11, 30.
  • Golasik, M., et al., 2016. Toxicokinetics and tissue distribution of titanium in ionic form after intravenous and oral administration. Toxicology Letters, 247, 56–61.
  • Gui, S., et al., 2013. Intragastric exposure to titanium dioxide nanoparticles induced nephrotoxicity in mice, assessed by physiological and gene expression modifications. Particle and Fibre Toxicology, 10, 4.
  • Hacisalihoglu, I., et al., 2014. Tribocorrosion properties of different type titanium alloys in simulated body fluid I. Wear, 12, 017.
  • Hazelhoff, M.H., et al., 2018. Renal expression of organic anion transporters is modified after mercuric chloride exposure: gender-related differences. Toxicology Letters, 295, 390–396.
  • Hazelhoff, M.H. and Torres, A.M., 2021. Effect of erythropoietin on mercury-induced nephrotoxicity: role of membrane transporters. Human & Experimental Toxicology, 40 (3), 515–525.
  • Heiene, R., Moe, L., and Mølmen, G., 2001. Calculation of urinary enzyme excretion, with renal structure and function in dogs with pyometra. Research in Veterinary Science, 70 (2), 129–137.
  • Hu, H., et al., 2018. RNA sequencing analysis shows that titanium dioxide nanoparticles induce endoplasmic reticulum stress, which has a central role in mediating plasma glucose in mice. Nanotoxicology, 12 (4), 341–356.,
  • Li, Y., et al., 2010. Cytotoxicity of titanium and titanium alloying elements. Journal of Dental Research, 89 (5), 493–497.
  • Liu, H., et al., 2009. Biochemical toxicity of nano-anatase TiO2 particles in mice. Biological Trace Element Research, 129 (1-3), 170–180. Erratum in: Biol. Trace Elem. Res., 2014, 160, 152.
  • Luo, Z., et al., 2020. Rethinking nano-TiO2 safety: overview of toxic effects in humans and aquatic animals. Small (Weinheim an Der Bergstrasse, Germany), 16 (36), e2002019.
  • Mathew, M.T., et al., 2009. Significance of tribocorrosion in biomedical applications: overview and current status. Advances in Tribology, 2009, 1–12.
  • Morgan, A., et al., 2017. Tiron ameliorates oxidative stress and inflammation in titanium dioxide nanoparticles induced nephrotoxicity of male rats. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie, 93, 779–787.
  • Niinomi, M., 2008b. Mechanical biocompatibilities of titanium alloys for biomedical applications. Journal of the Mechanical Behavior of Biomedical Materials, 1 (1), 30–42.
  • Niinomi, M., 2008a. Metallic biomaterials. Journal of Artificial Organs, 11 (3), 105–110.
  • Peters, R.J.B., et al., 2020. Silicon dioxide and titanium dioxide particles found in human tissues. Nanotoxicology, 14 (3), 420–432.
  • Price, C.P., Newall, R.G., and Boyd, J.C., 2005. Use of protein: creatinine ratio measurements on random urine samples for prediction of significant proteinuria: a systematic review. Clinical Chemistry, 51 (9), 1577–1586.
  • Pujalté, I., et al., 2017. Toxicokinetics of titanium dioxide (TiO2) nanoparticles after inhalation in rats. Toxicology Letters, 265, 77–85.
  • Rosner, M.H. and Bolton, W.K., 2006. Renal function testing. American Journal of Kidney Diseases, 47 (1), 174–183.
  • Sabolic, I., 2006. Common mechanisms in nephropathy induced by toxic metal. Nephron Physiol, 105, 106–114.
  • Shakeel, M., et al., 2016. Toxicity of nano-titanium dioxide (TiO2-NP) through various routes of exposure: a review. Biological Trace Element Research, 172 (1), 1–36.
  • Shi, H., et al., 2013. Titanium dioxide nanoparticles: a review of current toxicological data. Particle and Fibre Toxicology, 10, 15.
  • Sirota, J.C., Klawitter, J., and Edelstein, C.L.J., 2011. Biomarkers of acute kidney injury. Journal of Toxicology, 2011, 328120.
  • Smijs, T.G. and Pavel, S., 2011. Titanium dioxide and zinc oxide nanoparticles in sunscreens: focus on their safety and effectiveness. Nanotechnology, Science and Applications, 4, 95–112.
  • Trbojevich, R., et al., 2016. Comparative study of silver nanoparticles permeation using side-by-side and Franz diffusion cells. Journal of Nanoparticle Research, 18 (3), 1–12.
  • Trbojevich, R.A. and Torres, A.M., 2017. Biological synthesis, pharmacokinetic, and toxicity of different metal nanoparticles. In: M. Rai and R. Shegokar, eds. Metal Nanoparticles in Pharma. Basel, Switzerland: Springer International Publishing AG, 451–468.
  • Umbreit, T.H., et al., 2012. Tissue distribution and histopathological effects of titanium dioxide nanoparticles after intravenous or subcutaneous injection in mice. Journal of Applied Toxicology, 32 (5), 350–357.
  • Valentini, X., et al., 2019. Hepatic and renal toxicity induced by tio2 nanoparticles in rats: a morphological and metabonomic study. Journal of Toxicology, 2019, 5767012.
  • Wang, J., et al., 2007. Acute toxicity and biodistribution of different size titanium dioxide particles in mice after oral administration. Toxicology Letters, 168 (2), 176–185.
  • Weir, A., et al., 2012. Titanium dioxide nanoparticles in food and personal care products. Environmental Science & Technology, 46 (4), 2242–2250.
  • Westhuyzen, J., et al., 2003. Measurement of tubular enzymuria facilitates early detection of acute renal impairment in the intensive care unit. Nephrology Dialysis Transplantation, 18 (3), 543–551.
  • Xie, G., et al., 2011. Tissue distribution and excretion of intravenously administered titanium dioxide nanoparticles. Toxicology Letters, 205 (1), 55–61.

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