Drug and Chemical Toxicology, Volume 46, Issue 6 (2023)

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Drug and Chemical Toxicology, Volume 46, Issue 6 (2023)

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Research Articles

Article
Nigella sativa oil reduces oxidative/nitrosative stress in the salivary gland of rats exposed to total cranial irradiation
Saleh Mouket, Elif Demir, Arzu Yucel & Seyithan Taysi
Pages: 1051-1056
Published online: 21 Sep 2022
AbstractforNigella sativa oil reduces oxidative/nitrosative stress in the salivary gland of rats exposed to total cranial irradiation | Full Text | References | PDF (643.2 KB) | EPUB
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Article
Protective effects of a polyherbal medicine, Majoon Suranjan against bisphenol-A induced genetic, oxidative and tissue damages
Deepti Singh, Mohammad Afsar Khan, Kafil Akhtar, Sumbul Rehman, Sabiha Parveen, K. M. Yusuf Amin & Hifzur R. Siddique
Pages: 1057-1069
Published online: 19 Sep 2022
AbstractforProtective effects of a polyherbal medicine, Majoon Suranjan against bisphenol-A induced genetic, oxidative and tissue damages | Full Text | References | PDF (3.1 MB) | EPUB
  • 207 Views
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Article
Hepatoprotective effects of a chemically-characterized extract from artichoke (Cynara scolymus L.) against AFB1-induced toxicity in rats
Mostafa A. Nasef, Mokhtar I. Yousef, Doaa A. Ghareeb, Maria Augustyniak, Mourad A. M. Aboul-Soud & Abeer El Wakil
Pages: 1070-1082
Published online: 04 Oct 2022
AbstractforHepatoprotective effects of a chemically-characterized extract from artichoke (Cynara scolymus L.) against AFB1-induced toxicity in rats | Full Text | References | PDF (3 MB) | EPUB
  • 249 Views
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Article
Evaluation of subchronic toxicity of the compound of diphenhydramine hydrochloride and caffeine after 28 days of repeated oral administration in Sprague-Dawley rats and beagle dogs
Lijun Ren, Lang Yan, Wenjing Shi, Tiantian Zhang, Bijiang Geng, Jingjing Mao, Jiqianzhu Zhang, Yijun Tian, Haoneng Wang, Fangyuan Gao, Xiaoyu Dai, Jinfeng Li, Jing Gu, Yun Chen, Xiaofang Zhang, Jikuai Chen & Jiangbo Zhu
Pages: 1083-1099
Published online: 16 Nov 2022
AbstractforEvaluation of subchronic toxicity of the compound of diphenhydramine hydrochloride and caffeine after 28 days of repeated oral administration in Sprague-Dawley rats and beagle dogs | Full Text | References | PDF (2.7 MB) | EPUB
  • 146 Views
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Article
Pentoxifylline inhibits phosgene-induced lung injury via improving hypoxia
Xiao-di Zhang, Wei-hua Yu, Meng-meng Liu, Rui Liu, Hao Wu, Zhao Wang & Chun-xu Hai
Pages: 1100-1107
Published online: 11 Oct 2022
AbstractforPentoxifylline inhibits phosgene-induced lung injury via improving hypoxia | Full Text | References | PDF (2.2 MB) | EPUB
  • 109 Views
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Article
The molecular evaluation of thioredoxin (TXN1 & TXN2), thioredoxin reductase 1 (TXNRd1), and oxidative stress markers in a binary rat model of hypo- and hyperthyroidism after treatment with gallic acid
Zohreh Najafi, Elham Chamani, Asghar Zarban, Zohreh Rezaei & Gholamreza Sharifzadeh
Pages: 1108-1115
Published online: 31 Oct 2022
AbstractforThe molecular evaluation of thioredoxin (TXN1 & TXN2), thioredoxin reductase 1 (TXNRd1), and oxidative stress markers in a binary rat model of hypo- and hyperthyroidism after treatment with gallic acid | Full Text | References | PDF (1.2 MB) | EPUB
  • 162 Views
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Article
A comparative study on the sensitivity of selected freshwater fishes against triclosan exposure
Ramesh Neetha, John Nikhil & Kumari Chidambaran Chitra
Pages: 1116-1129
Published online: 18 Oct 2022
AbstractforA comparative study on the sensitivity of selected freshwater fishes against triclosan exposure | Full Text | References | PDF (5.3 MB) | EPUB
  • 124 Views
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Article
Renal tubular response to titanium dioxide nanoparticles exposure
María H. Hazelhoff, Romina P. Bulacio & Adriana M. Torres
Pages: 1130-1137
Published online: 18 Oct 2022
AbstractforRenal tubular response to titanium dioxide nanoparticles exposure | Full Text | References | PDF (1.1 MB) | EPUB
  • 198 Views
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Article
Effect of curcumin on lipid profile, fibrosis, and apoptosis in liver tissue in abemaciclib-administered rats
Zübeyir Huyut, Bünyamin Uçar, Fikret Altındağ, Kenan Yıldızhan & Mehmet Tahir Huyut
Pages: 1138-1146
Published online: 19 Oct 2022
AbstractforEffect of curcumin on lipid profile, fibrosis, and apoptosis in liver tissue in abemaciclib-administered rats | Full Text | References | PDF (3.6 MB) | EPUB
  • 431 Views
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Article
In vitro cytogenotoxic evaluation of aripiprazole on human peripheral lymphocytes and computational molecular docking analysis
Yasemin Eldemir Okay, İbrahim Halil Kenger, Hamit Yildiz, Mehmet Tahir Hüsunet, Lale Dönbak & Ahmet Kayraldiz
Pages: 1147-1153
Published online: 24 Oct 2022
AbstractforIn vitro cytogenotoxic evaluation of aripiprazole on human peripheral lymphocytes and computational molecular docking analysis | Full Text | References | PDF (1.4 MB) | EPUB
  • 284 Views
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Article
Synthesized gold nanoparticles mediated by Crassocephalum rubens extract down-regulate KIM-1/NGAL genes and inhibit oxidative stress in cadmium-induced kidney damage in rats
Olusola Bolaji Adewale, Scholastica Onyebuchi Anadozie, Regina T. Okpiri, Kikelomo Folake Jaiyesimi, Olutunmise V. Owolabi, Oluwatobiloba Akinlade, Tajudeen Olabisi Obafemi, Olukemi Adetutu Osukoya & Amos Onasanya
Pages: 1154-1161
Published online: 27 Oct 2022
AbstractforSynthesized gold nanoparticles mediated by Crassocephalum rubens extract down-regulate KIM-1/NGAL genes and inhibit oxidative stress in cadmium-induced kidney damage in rats | Full Text | References | PDF (2.1 MB) | EPUB
  • 140 Views
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Article
The preventive effects of Centaurea maroccana Ball. extract against oxidative stress induced by cisplatin in mice brains: in vitro and in vivo studies
Imane Aissous, Mouad Benrebai, Souad Ameddah, Ahmed Menad, Ramazan Erenler, Samir Benayache & Fadila Benayache
Pages: 1162-1175
Published online: 04 Nov 2022
AbstractforThe preventive effects of Centaurea maroccana Ball. extract against oxidative stress induced by cisplatin in mice brains: in vitro and in vivo studies | Full Text | References | PDF (3.7 MB) | EPUB
  • 229 Views
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Article
Influence of zinc oxide nanoparticles (ZnO NPs) on the hemocyte count and hemocyte-mediated immune responses of the Greater Wax Moth Galleria mellonella (Lepidoptera: Pyralidae)
Ata Eskin & Zahide Ulya Nurullahoğlu
Pages: 1176-1186
Published online: 04 Nov 2022
AbstractforInfluence of zinc oxide nanoparticles (ZnO NPs) on the hemocyte count and hemocyte-mediated immune responses of the Greater Wax Moth Galleria mellonella (Lepidoptera: Pyralidae) | Full Text | References | PDF (1.7 MB) | EPUB
  • 364 Views
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Article
Phycocyanin improved alcohol-induced hepatorenal toxicity and behavior impairment in Wistar rats
Boukari Oumayma, Khemissi Wahid, Ghodhbane Soumaya, Tebourbi Olfa, Khemais Ben Rhouma, Sakly Mohsen & Hallegue Dorsaf
Pages: 1187-1192
Published online: 07 Nov 2022
AbstractforPhycocyanin improved alcohol-induced hepatorenal toxicity and behavior impairment in Wistar rats | Full Text | References | PDF (766.1 KB) | EPUB
  • 144 Views
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Article
Protective effects of royal jelly and Echinacea against moxifloxacin-induced renal and hepatic injury in rats
Rasha E. Mostafa, Nermeen M. Shaffie & Rasha M. Allam
Pages: 1193-1202
Published online: 02 Nov 2022
AbstractforProtective effects of royal jelly and Echinacea against moxifloxacin-induced renal and hepatic injury in rats | Full Text | References | PDF (3.1 MB) | EPUB
  • 111 Views
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Article
Protective effects of Biebersteinia multifida on sub-chronic toxicity of DZN in male Wistar rats: biochemical, hematological, and oxidative stress indices
Fatemeh Esmailpour, Asieh Karimani, Mohammad Heidarpour & Amir Moghaddam Jafari
Pages: 1203-1211
Published online: 02 Nov 2022
AbstractforProtective effects of Biebersteinia multifida on sub-chronic toxicity of DZN in male Wistar rats: biochemical, hematological, and oxidative stress indices | Full Text | References | PDF (1.7 MB) | EPUB
  • 78 Views
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Article
Effect of Moringa oleifera leaf extract on valproate-induced oxidative damage in muscle
Onur Ertik, Umar Faruk Magaji, Ozlem Sacan & Refiye Yanardag
Pages: 1212-1222
Published online: 13 Nov 2022
AbstractforEffect of Moringa oleifera leaf extract on valproate-induced oxidative damage in muscle | Full Text | References | PDF (1.6 MB) | EPUB
  • 315 Views
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Article
Rutin ameliorates perfluorooctanoic acid-induced testicular injury in mice by reducing oxidative stress and improving lipid metabolism
Xinzhuang Ma, Xijuan Ren, Xuemin Zhang, Nathan Griffin, Hui Liu & Li Wang
Pages: 1223-1234
Published online: 13 Nov 2022
AbstractforRutin ameliorates perfluorooctanoic acid-induced testicular injury in mice by reducing oxidative stress and improving lipid metabolism | Full Text | References | PDF (3.2 MB) | EPUB
  • 227 Views
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Article
Changes in hormones, Leukocyte Telomere Length (LTL), and p16INK4a expression in SM-exposed individuals in favor of the cellular senescence
Susan K. Ardestani, Tahereh Jamali, Ali Taravati, Hossein Behboudi, Mohamad-Reza Vaez-Mahdavi, Elham Faghihzadeh & Tooba Ghazanfari
Pages: 1235-1241
Published online: 27 Dec 2022
AbstractforChanges in hormones, Leukocyte Telomere Length (LTL), and p16INK4a expression in SM-exposed individuals in favor of the cellular senescence | Full Text | References | PDF (1 MB) | EPUB
  • 146 Views
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Review Article

Review
Genotoxic and genoprotective effects of phytoestrogens: a systematic review
Ghada Tagorti, Burçin Yalçın, Merve Güneş, Ayşen Yağmur Kurşun & Bülent Kaya
Pages: 1242-1254
Published online: 05 Jan 2023
AbstractforGenotoxic and genoprotective effects of phytoestrogens: a systematic review | Full Text | References | PDF (2.3 MB) | EPUB | Supplemental
  • 235 Views
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