Varicocele-Induced Testicular Dysfunction May Be Associated with Disruption of Blood-Testis Barrier

REFERENCES

• Behrens J, Birchmeier W, , et al (1985): Dissociation of Madin-Darby canine kidney epithelial cells by the monoclonal antibody anti-arc-1: mechanistic aspects and identification of the antigen as a component related to uvomorulin. J Cell Biol 101:1307–1315.
   PubMed Web of Science ®Google Scholar
• Cameron DF, Snydle FE (1980): The blood-testis barrier in men with varicocele: a lanthanum tracer study. Fertil Steril 34:255–258.
   PubMed Web of Science ®Google Scholar
• Cameron DF, Snydle FE, , et al (1980): Ultrastructural alterations in the adluminal testicular compartment in men with varicocele. Fertil Steril 33:526–533.
   PubMed Web of Science ®Google Scholar
• Coburn M, Kim ED, Wheeler TM (1997): Testicular biopsy in male infertility evaluation. In: Infertility in the Male, 3rd edition. Lipshultz LI, Howards SS, (Eds). St. Louis: CV Mosby CO, pp 219–248.
   Google Scholar
• Cockett AT, Takihara H, Cosentino MJ (1984): The varicocele. Fertil Steril 41:5–11.
   PubMed Web of Science ®Google Scholar
• Dym M, Fawcett DW (1970): The blood-testis barrier in the rat and the physiological compartmentation of the seminiferous epithelium. Biol Reprod 3:308–326.
   PubMedGoogle Scholar
• Eskew LA, Watson NE, , et al (1993): Ultrasonographic diagnosis of varicoceles. Fertil Steril 60:693–697.
   PubMed Web of Science ®Google Scholar
• Golomb J, Vardinon N, , et al (1986): Demonstration of antispermatozoal antibodies in varicocele-related infertility with an enzyme-linked immunosorbent assay (ELISA). Fertil Steril 45:397–402.
   PubMed Web of Science ®Google Scholar
• Gumbiner B, Simons K (1986): A functional assay for proteins involved in establishing an epithelial occluding barrier: identification of a uvomorulin-like polypeptide. J Cell Biol 102:457–468.
   PubMed Web of Science ®Google Scholar
• Gumbiner B, Stevenson B, Grimaldi A (1988): The role of the cell adhesion molecule uvomorulin in the formation and maintenance of the epithelial junctional complex. J Cell Biol 107:1575–1587.
   PubMed Web of Science ®Google Scholar
• Gumbiner BM, McCrea PD (1993): Catenins as mediators of the cytoplasmic functions of cadherins. J Cell Sci Suppl 17:155–158.
   PubMedGoogle Scholar
• Hirano S, Kimoto N, , et al (1992): Identification of a neural alpha-catenin as a key regulator of cadherin function and multicellular organization. Cell 70:293–301.
   PubMed Web of Science ®Google Scholar
• Imamura Y, Itoh M, , et al (1999): Functional domains of alpha-catenin required for the strong state of cadherin-based cell adhesion. J Cell Biol 144:1311–1322.
   PubMed Web of Science ®Google Scholar
• Koksal IT, Ozcan F, , et al (2002): Expression of E-cadherin in prostate cancer in formalin-fixed, paraffin-embedded tissues: correlation with pathological features. Pathology 34:233–238.
   PubMed Web of Science ®Google Scholar
• Koksal IT, Tefekli A, , et al (2000): The role of reactive oxygen species in testicular dysfunction associated with varicocele. BJU Int 86:549–552.
   PubMed Web of Science ®Google Scholar
• Koksal IT, Usta M, , et al (2003): Potential role of reactive oxygen species on testicular pathology associated with infertility. Asian J Androl 5:95–99.
   PubMed Web of Science ®Google Scholar
• Koksal T, Erdogru T, , et al (2002): Effect of experimental varicocele in rats on testicular oxidative stress status. Andrologia 34:242–247.
   PubMed Web of Science ®Google Scholar
• Krishnadath KK, Tilanus HW, , et al (1997): Reduced expression of the cadherin-catenin complex in oesophageal adenocarcinoma correlates with poor prognosis. J Pathol 182:331–338.
   PubMed Web of Science ®Google Scholar
• Marks JL, McMahon R, Lipshultz LI (1986): Predictive parameters of successful varicocele repair. J Urol 136:609–612.
   PubMed Web of Science ®Google Scholar
• Mruk DD, Cheng CY (2004): Sertoli-Sertoli and Sertoli-germ cell interactions and their significance in germ cell movement in the seminiferous epithelium during spermatogenesis. Endocr Rev 25:747–806.
   PubMed Web of Science ®Google Scholar
• Naughton CK, Nangia AK, Agarwal A (2001): Pathophysiology of varicoceles in male infertility. Hum Reprod Update 7:473–481.
   PubMed Web of Science ®Google Scholar
• Pitelka DR, Taggart BN, Hamamoto ST (1983): Effects of extracellular calcium depletion on membrane topography and occluding junctions of mammary epithelial cells in culture. J Cell Biol 96:613–624.
   PubMed Web of Science ®Google Scholar
• Raitsina SS, Kurnosov AV, , et al (1979): Autoimmune nature of spermatogenesis disorders in varicocele models in rats. Biull Eksp Biol Med 87:44–48.
   PubMedGoogle Scholar
• Shook TE, Nyberg LM, , et al (1988): Pathological and immunological effects of surgically induced varicocele in juvenile and adult rats. Am J Reprod Immunol Microbiol 17:141–144.
   PubMed Web of Science ®Google Scholar
• Takeichi M (1991): Cadherin cell adhesion receptors as a morphogenetic regulator. Science 251:1451–1455.
   PubMed Web of Science ®Google Scholar
• Terquem A, Dadoune JP (1981): Morphological findings in varicocele: an ultrastructural study of 30 bilateral testicular biopsies. Int J Androl 4:515–531.
   PubMedGoogle Scholar
• Turner TT, Jones CE, Roddy MS (1987): Experimental varicocele does not affect the blood-testis barrier, epididymal electrolyte concentrations, or testicular blood gas concentrations. Biol Reprod 36:926–932.
   PubMed Web of Science ®Google Scholar
• World Health Organization (1992): Laboratory manual for examination of human Semen and Sperm-cervical Mukus interaction. In: 3rd edition. Cambridge: Cambridge University Press.
   Google Scholar
• World Health Organization (1993): WHO manual for the standardized investigation and diagnosis of the infertile couple. In: 1st edition. Cambridge: Cambridge University Press.
   Google Scholar
• Wu JC, Gregory CW, DePhilip RM (1993): Expression of E-cadherin in immature rat and mouse testis and in rat Sertoli cell cultures. Biol Reprod 49:1353–1361.
   PubMed Web of Science ®Google Scholar