An electroamalgamation approach to separate ⁴⁷Sc from neutron-activated ⁴⁶Ca target for use in cancer theranostics

References

• Bhattacharyya, S.; Dixit, M. (2011) Metallic radionuclides in the development of diagnostic and therapeutic radiopharmaceuticals. Dalton Transactions, 40 (23): 6112.
   PubMed Web of Science ®Google Scholar
• Cutler, C.S.; Hennkens, H.M.; Sisay, N.; Huclier-Markai, S.; Jurisson, S.S. (2013) Radiometals for combined imaging and therapy. Chemical Reviews, 113 (2): 858.
   PubMed Web of Science ®Google Scholar
• Minegishi, K.; Nagatsu, K.; Fukada, M.; Suzuki, H.; Ohya, T.; Zhang, M.R. (2016) Production of scandium-43 and -47 from a powdery calcium oxide target via the nat/44Ca(alpha,x)-channel. Applied Radiation and Isotopes, 116: 8.
   PubMed Web of Science ®Google Scholar
• Muller, C.; Bunka, M.; Haller, S.; Koster, U.; Groehn, V.; Bernhardt, P.; van der Meulen, N.; Turler, A.; Schibli, R. (2014) Promising prospects for 44Sc/47Sc-based theragnostics: Application of 47Sc for radionuclide tumor therapy in mice. Journal of Nuclear Medicine, 55 (10): 1658.
   PubMed Web of Science ®Google Scholar
• Kolsky, K.L.; Joshi, V.; Mausner, L.F.; Srivastava, S.C. (1998) Radiochemical purification of no-carrier-added scandium-47 for radioimmunotherapy. Applied Radiation and Isotopes, 49 (12): 1541.
   PubMed Web of Science ®Google Scholar
• Lahiri, S.; Banerjee, S.; Das, N.R. (1996) LLX separation of carrier-free 47Sc, 48V and 48,49,51Cr produced in α-particle activated titanium with HDEHP. Applied Radiation and Isotopes, 47 (1): 1–6.
   Web of Science ®Google Scholar
• Banerjee, S.; Das, N.R.; Lahiri, S. (1995) Sequential separation of carrier free 47Sc, 48V and 48,49,51Cr from α-particle activated titanium with TOA. Radiochimica Acta, 69: 61–64.
   Web of Science ®Google Scholar
• Kolsky, K.L.; Mausner, L.F.; Mease, R.C.; Chinol, M.; Straub, R.F.; Meinken, G.E.; Steplewski, Z.; Srivastava, S.C. (1992) Evaluation of reactor produced Sc-47 for radioimmunotherapy. Journal of Nuclear Medicine, 33: 900.
   Google Scholar
• International Atomic Energy Agency. Operation Research Reactors in the World [database]. Available at: www.naweb.iaea.org/napc/physics/research_reactors/database/RR%20Data%20Base/datasets/foreword_home.html.
   Google Scholar
• Valdovinos, H.F.; Hernandez, R.; Barnhart, T.E.; Graves, S.; Cai, W.; Nickles, R.J. (2014) Separation of cyclotron-produced 44Sc from a natural calcium target using a dipentyl pentylphosphonate functionalized extraction resin. Applied Radiation and Isotopes, 95: 23–29.
   PubMed Web of Science ®Google Scholar
• Müller, C.; Bunka, M.; Reber, J.; Fischer, C.; Zhernosekov, K.; Türler, A; Schibli, R. (2013) Promises of cyclotron-produced 44Sc as a diagnostic match for trivalent β-emitters: In vitro and in vivo study of a 44Sc-DOTA-folate conjugate. Journal of Nuclear Medicine, 54: 2168.
   PubMed Web of Science ®Google Scholar
• Hernandez, R.; Valdovinos, H.F.; Yang, Y.; Chakravarty, R.; Hong, H.; Barnhart, T.E.; Cai, W. (2014) 44Sc: An attractive isotope for peptide-based PET imaging. Molecular Pharmaceutics, 11: 2954.
   PubMed Web of Science ®Google Scholar
• Chakravarty, R.; Chakraborty, S.; Ram, R.; Nair, K.V.; Rajeswari, A.; Sarma, H.D.; Dash, A. (2016) Palliative care of bone pain due to skeletal metastases: Exploring newer avenues using neutron activated 45Ca. Nuclear Medicine and Biology, 43 (2): 140.
   PubMed Web of Science ®Google Scholar
• Chakravarty, R.; Dash, A.; Pillai, M.R.A. (2012) Electrochemical separation is an attractive strategy for development of radionuclide generators for medical applications. Current Radiopharmaceuticals, 5 (3): 271.
   PubMedGoogle Scholar
• Koumarianou, E.; Pawlak, D.; Korsak, A.; Mikolajczak, R. (2011) Comparison of receptor affinity of natSc-DOTA-TATE versus natGa-DOTA-TATE. Nuclear Medicine Review. Central & Eastern Europe, 14 (2): 85–89.
   PubMedGoogle Scholar
• Chakraborty, S.; Chakravarty, R.; Vatsa, R.; Bhusari, P.; Sarma, H.D.; Shukla, J.; Mittal, B.R.; Dash, A. (2016) Toward realization of ‘mix-and-use’ approach in ⁶⁸Ga radiopharmacy: Preparation, evaluation and preliminary clinical utilization of ⁶⁸Ga-labeled NODAGA-coupled RGD peptide derivative. Nuclear Medicine and Biology, 43 (1): 116.
   PubMed Web of Science ®Google Scholar
• Shukla, J.; Vatsa, R.; Garg, N.; Bhusari, P.; Watts, A.; Mittal, B.R. (2010) Quality control of positron emission tomography radiopharmaceuticals: An institutional experience. Indian Journal of Nuclear Medicine, 28: 200.
   Google Scholar
• Chakravarty, R.; Das, T.; Venkatesh, M.; Dash, A. (2012) An electro-amalgamation approach to produce 175Yb suitable for radiopharmaceutical applications. Radiochimica Acta, 100: 255.
   Web of Science ®Google Scholar
• Legal status of Ayurvedic, Siddha and Unani medicines. Order issued by Government of India, Department of Ayush, F.No. K-11020/5/97-DCC (AYUSH) 2005.
   Google Scholar