Deep eutectic solvents for sustainable extraction of polyphenols and saponins from plant sources: assessment of the impact of influencing factors

References

• Markets & Markets. Plant Extracts Market by Product Type (Oleoresins, Essential Oils, Flavonoids, Alkaloids, Carotenoids), Application (Food & Beverages, Cosmetics, Pharmaceuticals, Dietary Supplements), Form, Source and Region-Global Forecast to 2027; 2023. https://www.marketsandmarkets.com/Market-Reports/plant-extracts-market-942.html.
   Google Scholar
• Şahin, S. Tailor-Designed Deep Eutectic Liquids as a Sustainable Extraction Media: An Alternative to Ionic Liquids. J. Pharm. Biomed. Anal. 2019, 174, 324–329. DOI: 10.1016/j.jpba.2019.05.059.
   PubMed Web of Science ®Google Scholar
• Jessop, P. G. Searching for Green Solvents. Green Chem. 2011, 13 (6), 1391–1398. DOI: 10.1039/c0gc00797h.
   Google Scholar
• Ruesgas-Ramón, M.; Figueroa-Espinoza, M. C.; Durand, E. Application of Deep Eutectic Solvents (DES) for Phenolic Compounds Extraction: Overview, Challenges, and Opportunities. J. Agric. Food. Chem. 2017, 65(18), 3591–3601. DOI: 10.1021/acs.jafc.7b01054.
   PubMed Web of Science ®Google Scholar
• Choi, Y. H.; Verpoorte, R. Green Solvents for the Extraction of Bioactive Compounds from Natural Products Using Ionic Liquids and Deep Eutectic Solvents. Curr. Opin. Food Sci. 2019, 26, 87–93. DOI: 10.1016/j.cofs.2019.04.003.
   Web of Science ®Google Scholar
• Murador, D. C.; De Souza Mesquita, L. M.; Vannuchi, N.; Braga, A. R. C.; De Rosso, V. V. Bioavailability and Biological Effects of Bioactive Compounds Extracted with Natural Deep Eutectic Solvents and Ionic Liquids: Advantages Over Conventional Organic Solvents. Curr. Opin. Food Sci. 2019, 26, 25–34. DOI: 10.1016/j.cofs.2019.03.002.
   Web of Science ®Google Scholar
• El Achkar, T.; Greige-Gerges, H.; Fourmentin, S. Basics and Properties of Deep Eutectic Solvents: A Review. Environ. Chem. Lett. 2021, 19(4), 3397–3408. DOI: 10.1007/s10311-021-01225-8.
   Web of Science ®Google Scholar
• Smith, E. L.; Abbott, A. P.; Ryder, K. S. Deep Eutectic Solvents (DESs) and Their Applications. Chem. Rev. 2014, 114(21), 11060–11082. DOI: 10.1021/cr300162p.
   PubMed Web of Science ®Google Scholar
• Skarpalezos, D.; Detsi, A. Deep Eutectic Solvents as Extraction Media for Valuable Flavonoids from Natural Sources. Applied Sciences. 2019, 9(19), 4169. DOI: 10.3390/app9194169.
   Google Scholar
• Chen, Y.; Mu, T. Revisiting Greenness of Ionic Liquids and Deep Eutectic Solvents. Green Chem. Eng. 2021, 2(2), 174–186. DOI: 10.1016/j.gce.2021.01.004.
   Google Scholar
• Wazeer, I.; AlNashef, I. M.; Al-Zahrani, A. A.; Hadj-Kali, M. K. The Subtle but Substantial Distinction Between Ammonium- and Phosphonium-Based Deep Eutectic Solvents. J. Mol. Liq. 2021, 332, 115838. DOI: 10.1016/j.molliq.2021.115838.
   Web of Science ®Google Scholar
• Zhang, X.; Su, J.; Chu, X.; Wang, X. A Green Method of Extracting and Recovering Flavonoids from Acanthopanax Senticosus Using Deep Eutectic Solvents. Molecules. 2022, 27(3), 923. DOI: 10.3390/molecules27030923.
   PubMed Web of Science ®Google Scholar
• Du, G.; Hong, W.; Li, Z.; Liu, Y.; Wang, C. Process Optimization of Deep Eutectic Solvent-Based Microwave-Assisted Extraction of Flavonoids from Ziziphi Spinosae Semen Using Response Surface Methodology. Food Sci. Technol. 2023, 43, e122622. DOI: 10.1590/fst.122622.
   Google Scholar
• Guan, S.; Li, Z.; Xu, B.; Wu, J.; Wang, N.; Zhang, J.; Han, J.; Guan, T.; Wang, J.; Li, K. Cyclodextrin-Based Deep Eutectic Solvents for Efficient Extractive and Oxidative Desulfurization Under Room Temperature. Chem. Eng. J. 2022, 441, 136022. DOI: 10.1016/j.cej.2022.136022.
   Web of Science ®Google Scholar
• Patil, S. S.; Rathod, V. K. Extraction and Purification of Curcuminoids from Curcuma Longa Using Microwave Assisted Deep Eutectic Solvent Based System and Cost Estimation. Process Biochem. 2023, 126, 61–71. DOI: 10.1016/j.procbio.2022.11.010.
   Web of Science ®Google Scholar
• Florindo, C.; Oliveira, F. S.; Rebelo, L. P. N.; Fernandes, A. M.; Marrucho, I. M. Insights into the Synthesis and Properties of Deep Eutectic Solvents Based on Cholinium Chloride and Carboxylic Acids. ACS Sustain. Chem. Eng. 2014, 2(10), 2416–2425. DOI: 10.1021/sc500439w.
   Web of Science ®Google Scholar
• Crawford, D. E.; Wright, L. A.; James, S. L.; Abbott, A. P. Efficient Continuous Synthesis of High Purity Deep Eutectic Solvents by Twin Screw Extrusion. Chem. Commun. 2016, 52(22), 4215–4218. DOI: 10.1039/C5CC09685E.
   PubMed Web of Science ®Google Scholar
• Shekaari, H.; Zafarani-Moattar, M. T.; Mokhtarpour, M. Effective Ultrasonic-Assisted Extraction and Solubilization of Curcuminoids from Turmeric by Using Natural Deep Eutectic Solvents and Imidazolium-Based Ionic Liquids. J. Mol. Liq. 2022, 360, 119351. DOI: 10.1016/j.molliq.2022.119351.
   Web of Science ®Google Scholar
• Gomez, F. J. V.; Espino, M.; Fernández, M. A.; Silva, M. F. A Greener Approach to Prepare Natural Deep Eutectic Solvents. ChemistrySelect. 2018, 3(22), 6122–6125. DOI: 10.1002/slct.201800713.
   Web of Science ®Google Scholar
• Farooq, M. Q.; Abbasi, N. M.; Anderson, J. L. Deep Eutectic Solvents in Separations: Methods of Preparation, Polarity, and Applications in Extractions and Capillary Electrochromatography. J. Chromatogr. A 2020, 1633, 461613. 10.1016/j.chroma.2020.461613.
   Google Scholar
• Gutiérrez, M. C.; Ferrer, M. L.; Mateo, C. R.; Del Monte, F. Freeze-Drying of Aqueous Solutions of Deep Eutectic Solvents: A Suitable Approach to Deep Eutectic Suspensions of Self-Assembled Structures. Langmuir. 2009, 25(10), 5509–5515. DOI: 10.1021/la900552b.
   PubMed Web of Science ®Google Scholar
• Zhang, M.; Tian, R.; Han, H.; Wu, K.; Wang, B.; Liu, Y.; Zhu, Y.; Lu, H.; Liang, B. Preparation Strategy and Stability of Deep Eutectic Solvents: A Case Study Based on Choline Chloride-Carboxylic Acid. J. Clean. Prod. 2022, 345, 131028. DOI: 10.1016/j.jclepro.2022.131028.
   Web of Science ®Google Scholar
• Ali, M. C.; Chen, J.; Zhang, H.; Li, Z.; Zhao, L.; Qiu, H. Effective Extraction of Flavonoids from Lycium Barbarum L. Fruits by Deep Eutectic Solvents-Based Ultrasound-Assisted Extraction. Talanta. 2019, 203, 16–22. DOI: 10.1016/j.talanta.2019.05.012.
   PubMed Web of Science ®Google Scholar
• Mansur, A. R.; Song, N.-E.; Jang, H. W.; Lim, T.-G.; Yoo, M.; Nam, T. G. Optimizing the Ultrasound-Assisted Deep Eutectic Solvent Extraction of Flavonoids in Common Buckwheat Sprouts. Food Chem. 2019, 293, 438–445. DOI: 10.1016/j.foodchem.2019.05.003.
   PubMed Web of Science ®Google Scholar
• Qi, X.-L.; Peng, X.; Huang, Y.-Y.; Li, L.; Wei, Z.-F.; Zu, Y.-G.; Fu, Y.-J. Green and Efficient Extraction of Bioactive Flavonoids from Equisetum Palustre L. by Deep Eutectic Solvents-Based Negative Pressure Cavitation Method Combined with Macroporous Resin Enrichment. Ind. Crops Prod. 2015, 70, 142–148. DOI: 10.1016/j.indcrop.2015.03.026.
   Web of Science ®Google Scholar
• Roohinejad, S.; Koubaa, M.; Barba, F. J.; Greiner, R.; Orlien, V.; Lebovka, N. I. Negative Pressure Cavitation Extraction: A Novel Method for Extraction of Food Bioactive Compounds from Plant Materials. Trends Food Sci. Technol. 2016, 52, 98–108. DOI: 10.1016/j.tifs.2016.04.005.
   Web of Science ®Google Scholar
• Zainal-Abidin, M. H.; Hayyan, M.; Hayyan, A.; Jayakumar, N. S. New Horizons in the Extraction of Bioactive Compounds Using Deep Eutectic Solvents: A Review. Analytica Chimica Acta. 979, 1–23. DOI:10.1016/j.aca.2017.05.012.
   PubMed Web of Science ®Google Scholar
• Wang, H.; Ma, X.; Cheng, Q.; Wang, L.; Zhang, L. Deep Eutectic Solvent-Based Ultrahigh Pressure Extraction of Baicalin from Scutellaria Baicalensis Georgi. Molecules. 2018, 23(12), 3233. DOI: 10.3390/molecules23123233.
   PubMed Web of Science ®Google Scholar
• Prentice, P.; Cuschieri, A.; Dholakia, K.; Prausnitz, M.; Campbell, P. Membrane Disruption by Optically Controlled Microbubble Cavitation. Nature Phys. 2005, 1(2), 107–110. DOI: 10.1038/nphys148.
   Web of Science ®Google Scholar
• Perera, C. O.; Alzahrani, M. A. J. Ultrasound as a Pre-Treatment for Extraction of Bioactive Compounds and Food Safety: A Review. LWT. 2021, 142, 111114. DOI: 10.1016/j.lwt.2021.111114.
   Web of Science ®Google Scholar
• Nam, M. W.; Zhao, J.; Lee, M. S.; Jeong, J. H.; Lee, J. Enhanced Extraction of Bioactive Natural Products Using Tailor-Made Deep Eutectic Solvents: Application to Flavonoid Extraction from Flos Sophorae. Green Chem. 2015, 17(3), 1718–1727. DOI: 10.1039/C4GC01556H.
   Web of Science ®Google Scholar
• Tang, W.; Li, G.; Chen, B.; Zhu, T.; Row, K. H. Evaluating Ternary Deep Eutectic Solvents as Novel Media for Extraction of Flavonoids from Ginkgo Biloba. Sep. Sci. Technol. 2017, 52(1), 91–99. DOI: 10.1080/01496395.2016.1247864.
   Google Scholar
• Rosarina, D.; Narawangsa, D. R.; Chandra, N. S. R.; Sari, E.; Hermansyah, H. Optimization of Ultrasonic—Assisted Extraction (UAE) Method Using Natural Deep Eutectic Solvent (NADES) to Increase Curcuminoid Yield from Curcuma Longa L., Curcuma Xanthorrhiza, and Curcuma Mangga Val. Molecules. 2022, 27(18), 6080. DOI: 10.3390/molecules27186080.
   PubMed Web of Science ®Google Scholar
• Jeong, K. M.; Lee, M. S.; Nam, M. W.; Zhao, J.; Jin, Y.; Lee, D.-K.; Kwon, S. W.; Jeong, J. H.; Lee, J. Tailoring and Recycling of Deep Eutectic Solvents as Sustainable and Efficient Extraction Media. J. Chromatogr. A. 2015, 1424, 10–17. DOI: 10.1016/j.chroma.2015.10.083.
   PubMed Web of Science ®Google Scholar
• Li, L.; Liu, J.-Z.; Luo, M.; Wang, W.; Huang, Y.-Y.; Efferth, T.; Wang, H.-M.; Fu, Y.-J. Efficient Extraction and Preparative Separation of Four Main Isoflavonoids from Dalbergia Odorifera T. Chen Leaves by Deep Eutectic Solvents-Based Negative Pressure Cavitation Extraction Followed by Macroporous Resin Column Chromatography. J. Chromatogr. B. 2016, 1033-1034, 40–48. DOI: 10.1016/j.jchromb.2016.08.005.
   PubMed Web of Science ®Google Scholar
• Yang, G.-Y.; Song, J.-N.; Chang, Y.-Q.; Wang, L.; Zheng, Y.-G.; Zhang, D.; Guo, L. Natural Deep Eutectic Solvents for the Extraction of Bioactive Steroidal Saponins from Dioscoreae Nipponicae Rhizoma. Molecules. 2021, 26(7), 2079. DOI: 10.3390/molecules26072079.
   PubMed Web of Science ®Google Scholar
• Cao, J.; Wu, G.; Wang, L.; Cao, F.; Jiang, Y.; Zhao, L. Oriented Deep Eutectic Solvents as Efficient Approach for Selective Extraction of Bioactive Saponins from Husks of Xanthoceras Sorbifolia Bunge. Antioxidants. 2022, 11(4), 736. DOI: 10.3390/antiox11040736.
   Web of Science ®Google Scholar
• Pérez-Jiménez, J.; Neveu, V.; Vos, F.; Scalbert, A. Identification of the 100 Richest Dietary Sources of Polyphenols: An Application of the Phenol-Explorer Database. Eur. J. Clin. Nutr. 2010, 64(S3), 112–120. DOI: 10.1038/ejcn.2010.221.
   PubMedGoogle Scholar
• Sharma, K.; Kaur, R.; Kumar, S.; Saini, R. K.; Sharma, S.; Pawde, S. V.; Kumar, V. Saponins: A Concise Review on Food Related Aspects. Appl. & Heal Impl. Food Chem. Adv. 2023, 2, 100191. DOI: 10.1016/j.focha.2023.100191.
   Google Scholar
• Patil, S. S.; Pathak, A.; Rathod, V. K. Optimization and Kinetic Study of Ultrasound Assisted Deep Eutectic Solvent Based Extraction: A Greener Route for Extraction of Curcuminoids from Curcuma Longa. Ultrason Sonochem. 2021, 70, 105267. DOI: 10.1016/j.ultsonch.2020.105267.
   PubMed Web of Science ®Google Scholar
• Tu, Y.; Li, L.; Fan, W.; Liu, L.; Wang, Z.; Yang, L. Development of Green and Efficient Extraction of Bioactive Ginsenosides from Panax Ginseng with Deep Eutectic Solvents. Molecules. 2022, 27(14), 4339. DOI: 10.3390/molecules27144339.
   PubMed Web of Science ®Google Scholar
• Zhou, R.-R.; Huang, J.-H.; He, D.; Yi, Z.-Y.; Zhao, D.; Liu, Z.; Zhang, S.-H.; Huang, L.-Q. Green and Efficient Extraction of Polysaccharide and Ginsenoside from American Ginseng (Panax Quinquefolius L.) by Deep Eutectic Solvent Extraction and Aqueous Two-Phase System. Molecules. 2022, 27(10), 3132. DOI: 10.3390/molecules27103132.
   PubMed Web of Science ®Google Scholar
• Zhao, B.-Y.; Xu, P.; Yang, F.-X.; Wu, H.; Zong, M.-H.; Lou, W.-Y. Biocompatible Deep Eutectic Solvents Based on Choline Chloride: Characterization and Application to the Extraction of Rutin from Sophora Japonica. ACS Sustain. Chem. Eng. 2015, 3(11), 2746–2755. DOI: 10.1021/acssuschemeng.5b00619.
   Web of Science ®Google Scholar
• Chen, X.; Lei, Z.; Cao, J.; Zhang, W.; Wu, R.; Cao, F.; Guo, Q.; Wang, J. Traditional Uses, Phytochemistry, Pharmacology and Current Uses of Underutilized Xanthoceras Sorbifolium Bunge: A Review. J. Ethnopharmacol. 2022, 283, 114747. DOI: 10.1016/j.jep.2021.114747.
   PubMed Web of Science ®Google Scholar
• Feng, Z.; Yang, D.; Guo, J.; Bo, Y.; Zhao, L.; An, M. Optimization of Natural Deep Eutectic Solvents Extraction of Flavonoids from Xanthoceras Sorbifolia Bunge by Response Surface Methodology. Sustain. Chem. Pharm. 2023, 31, 100904. DOI: 10.1016/j.scp.2022.100904.
   Web of Science ®Google Scholar
• Suresh, P. S.; Singh, P. P.; Anmol; Kapoor, S.; Padwad, Y. S.; Sharma, U. Lactic Acid-Based Deep Eutectic Solvent: An Efficient Green Media for the Selective Extraction of Steroidal Saponins from Trillium Govanianum. Sep. Purif. Technol. 2022, 294, 121105. DOI: 10.1016/j.seppur.2022.121105.
   Web of Science ®Google Scholar
• Liu, J.-Z.; Lin, Z.-X.; Kong, W.-H.; Zhang, C.-C.; Yuan, Q.; Fu, Y.-J.; Cui, Q. Ultrasonic-Assisted Extraction-Synergistic Deep Eutectic Solvents for Green and Efficient Incremental Extraction of Paris Polyphylla Saponins. J. Mol. Liq. 2022, 368, 120644. DOI: 10.1016/j.molliq.2022.120644.
   Web of Science ®Google Scholar
• Jayaprakasha, G. K.; Jaganmohan Rao, L.; Sakariah, K. K. Antioxidant Activities of Curcumin, Demethoxycurcumin and Bisdemethoxycurcumin. Food Chem. 2006, 98(4), 720–724. DOI: 10.1016/j.foodchem.2005.06.037.
   Web of Science ®Google Scholar
• Sharifi-Rad, J.; Rayess, Y. E.; Rizk, A. A.; Sadaka, C.; Zgheib, R.; Zam, W.; Sestito, S.; Rapposelli, S.; Neffe-Skocińska, K.; Zielińska, D., et al. Turmeric and Its Major Compound Curcumin on Health: Bioactive Effects and Safety Profiles for Food. Pharm. Biotech & Medi App. Front. Pharmacol. 2020, 11, 01021. DOI: 10.3389/fphar.2020.01021.
   Google Scholar
• Saffarionpour, S.; Diosady, L. L. Delivery of Curcumin Through Colloidal Systems and Its Applications in Functional Foods. Curr. Opin. Food Sci. 2022, 43, 155–162. DOI: 10.1016/j.cofs.2021.12.003.
   Web of Science ®Google Scholar
• Olivera, A.; Moore, T. W.; Hu, F.; Brown, A. P.; Sun, A.; Liotta, D. C.; Snyder, J. P.; Yoon, Y.; Shim, H.; Marcus, A. I., et al. Inhibition of the NF-Κb Signaling Pathway by the Curcumin Analog, 3,5-Bis(2-Pyridinylmethylidene)-4-Piperidone (EF31): Anti-Inflammatory and Anti-Cancer Properties. Int. Immunopharmacol. 2012, 12(2), 368–377. DOI: 10.1016/j.intimp.2011.12.009.
   PubMed Web of Science ®Google Scholar
• Nakagawa, Y.; Mukai, S.; Yamada, S.; Matsuoka, M.; Tarumi, E.; Hashimoto, T.; Tamura, C.; Imaizumi, A.; Nishihira, J.; Nakamura, T. Short-Term Effects of Highly-Bioavailable Curcumin for Treating Knee Osteoarthritis: A Randomized, Double-Blind, Placebo-Controlled Prospective Study. J. Orthop. Sci. 2014, 19(6), 933–939. DOI: 10.1007/s00776-014-0633-0.
   PubMed Web of Science ®Google Scholar
• Saffarionpour, S.; Diosady, L. L. Curcumin, a Potent Therapeutic Nutraceutical and Its Enhanced Delivery and Bioaccessibility by Pickering Emulsions. Drug Deli & Trans Res. 2022, 12(1), 124–157. DOI: 10.1007/s13346-021-00936-3.
   PubMed Web of Science ®Google Scholar
• Waman, A. A.; Bohra, P.; Sounderarajan, A. Propagule Size Affects Yield and Quality of Curcuma Mangga Val. et Zijp.: An Important Medicinal Spice. Ind. Crops Prod. 2018, 124, 36–43. DOI: 10.1016/j.indcrop.2018.07.011.
   Web of Science ®Google Scholar
• Awin, T.; Mediani, A.; Mohd Faudzi, S. M.; Maulidiani; Leong, S. W.; Shaari, K.; Abas, F. Identification of α-Glucosidase Inhibitory Compounds from Curcuma Mangga Fractions. Int. J. Food. Prop. 2020, 23(1), 154–166. DOI: 10.1080/10942912.2020.1716792.
   Web of Science ®Google Scholar
• Lee, H.-J.; Kang, S.-M.; Jeong, S.-H.; Chung, K.-H.; Kim, B.-I. Antibacterial Photodynamic Therapy with Curcumin and Curcuma Xanthorrhiza Extract against Streptococcus Mutans. Photodiagnosis. Photodyn. Ther. 2017, 20, 116–119. DOI: 10.1016/j.pdpdt.2017.09.003.
   PubMed Web of Science ®Google Scholar
• Lukitaningsih, E.; Rohman, A.; Rafi, M.; Windarsih, A. In Vivo Antioxidant Activities of Curcuma Longa and Curcuma Xanthorrhiza: A Review. Food Res. 2019, 4(1), 13–19. DOI: 10.26656/fr.2017.4(1).172.
   Google Scholar
• Liu, J.-L.; Li, L.-Y.; He, G.-H. Optimization of Microwave-Assisted Extraction Conditions for Five Major Bioactive Compounds from Flos Sophorae Immaturus (Cultivars of Sophora Japonica L.) Using Response Surface Methodology. Molecules. 2016, 21(3), 296. DOI: 10.3390/molecules21030296.
   PubMed Web of Science ®Google Scholar
• Dos Santos, J. S.; Suzan, A. J.; Bonafé, G. A.; Fernandes, A. M. A. D. P.; Longato, G. B.; Antônio, M. A.; Carvalho, P. D. O.; Ortega, M. M. Kaempferol and Biomodified Kaempferol from Sophora Japonica Extract as Potential Sources of Anti-Cancer Polyphenolics Against High Grade Glioma Cell Lines. IJMS. 2023, 24(13), 10716. DOI: 10.3390/ijms241310716.
   Google Scholar
• Zang, E.; Qiu, B.; Chen, N.; Li, C.; Liu, Q.; Zhang, M.; Liu, Y.; Li, M. Xanthoceras Sorbifolium Bunge: A Review on Botany, Phytochemistry, Pharmacology, and Applications. Front. Pharmacol. 2021, 12, 708549. DOI: 10.3389/fphar.2021.708549.
   PubMed Web of Science ®Google Scholar
• Zheng, Y.; Zhou, S.; Zhang, H.; Lu, Z.; Deng, R.; Feng, Y.; Liu, P.; Regmi, B. Comparative Study of the Flavonoid Content in Radix Scutellaria from Different Cultivation Areas in China. Int. J. Anal. Chem. 2023, 1–13. DOI: 10.1155/2023/3754549.
   Web of Science ®Google Scholar
• Liu, X.; Peng, X.; Cen, S.; Yang, C.; Ma, Z.; Shi, X. Wogonin Induces Ferroptosis in Pancreatic Cancer Cells by Inhibiting the Nrf2/GPX4 Axis. Front. Pharmacol. 2023, 14, 1129662. DOI: 10.3389/fphar.2023.1129662.
   PubMed Web of Science ®Google Scholar
• Morshed, A. K. M. H.; Paul, S.; Hossain, A.; Basak, T.; Hossain Md, S.; Hasan Md, M.; Hasibuzzaman Md, A.; Rahaman, T.; Mia Md, A. R.; Shing, P., et al. Baicalein as Promising Anticancer Agent: A Comprehensive Analysis on Molecular Mechanisms and Therapeutic Perspectives. Cancers. 2023, 15(7), 2128. DOI: 10.3390/cancers15072128.
   PubMed Web of Science ®Google Scholar
• Shin, B.-K.; Kwon, S. W.; Park, J. H. Chemical Diversity of Ginseng Saponins from Panax Ginseng. J. Ginseng Res. 2015, 39(4), 287–298. DOI: 10.1016/j.jgr.2014.12.005.
   PubMed Web of Science ®Google Scholar
• Kim, J.-H. Pharmacological and Medical Applications of Panax Ginseng and Ginsenosides: A Review for Use in Cardiovascular Diseases. J. Ginseng Res. 2018, 42(3), 264–269. DOI: 10.1016/j.jgr.2017.10.004.
   PubMed Web of Science ®Google Scholar
• Rawat, J. M.; Pandey, S.; Rawat, B.; Rai, N.; Preeti, P.; Thakur, A.; Butola, J. S.; Bachheti, R. K.; Wang, C.-H. Traditional Uses, Active Ingredients, and Biological Activities of Paris Polyphylla Smith: A Comprehensive Review of an Important Himalayan Medicinal Plant. J. Chem. 2023, 1–18. DOI: 10.1155/2023/7947224.
   Web of Science ®Google Scholar
• Bai, Y.; Zhang, X.-F.; Wang, Z.; Zheng, T.; Yao, J. Deep Eutectic Solvent with Bifunctional Brønsted-Lewis Acids for Highly Efficient Lignocellulose Fractionation. Bioresources Technol. 2022, 347, 126723. DOI: 10.1016/j.biortech.2022.126723.
   PubMed Web of Science ®Google Scholar
• Yu, L.; Bulone, V. De-Glycosylation and Enhanced Bioactivity of Flavonoids from Apple Pomace During Extraction with Deep Eutectic Solvents. Green Chem. 2021, 23(18), 7199–7209. DOI: 10.1039/D1GC01928G.
   Web of Science ®Google Scholar
• Li, G.; Jiang, Y.; Liu, X.; Deng, D. New Levulinic Acid-Based Deep Eutectic Solvents: Synthesis and Physicochemical Property Determination. J. Mol. Liq. 2016, 222, 201–207. DOI: 10.1016/j.molliq.2016.07.039.
   Web of Science ®Google Scholar
• Tzani, A.; Kalafateli, S.; Tatsis, G.; Bairaktari, M.; Kostopoulou, I.; Pontillo, A. R. N.; Detsi, A. Natural Deep Eutectic Solvents (NaDess) as Alternative Green Extraction Media for Ginger (Zingiber Officinale Roscoe). Sustain. Chem. 2021, 2(4), 576–598. DOI: 10.3390/suschem2040032.
   Google Scholar
• Like, B. D.; Uhlenbrock, C. E.; Panzer, M. J. A Quantitative Thermodynamic Metric for Identifying Deep Eutectic Solvents. Phys. Chem. Chem. Phys. 2023, 25(11), 7946–7950. DOI: 10.1039/D3CP00555K.
   PubMed Web of Science ®Google Scholar
• Kollau, L. J. B. M.; Vis, M.; Van Den Bruinhorst, A.; Esteves, A. C. C.; Tuinier, R. Quantification of the Liquid Window of Deep Eutectic Solvents. Chem. Commun. 2018, 54(95), 13351–13354. DOI: 10.1039/C8CC05815F.
   PubMed Web of Science ®Google Scholar
• González De Castilla, A.; Bittner, J. P.; Müller, S.; Jakobtorweihen, S.; Smirnova, I. Thermodynamic and Transport Properties Modeling of Deep Eutectic Solvents: A Review on G e -Models, Equations of State, and Molecular Dynamics. J. Chem. Eng, Data. 2020, 65(3), 943–967. DOI: 10.1021/acs.jced.9b00548.
   Web of Science ®Google Scholar
• Van Den Bruinhorst, A.; Costa Gomes, M. Is There Depth to Eutectic Solvents? Curr. Opin. Green Sustain. Chem. 2022, 37, 100659. DOI: 10.1016/j.cogsc.2022.100659.
   Web of Science ®Google Scholar
• Kalhor, P.; Ghandi, K. Deep Eutectic Solvents for Pretreatment, Extraction, and Catalysis of Biomass and Food Waste. Molecules. 24(22), 4012. DOI: 10.3390/molecules24224012.
   PubMed Web of Science ®Google Scholar
• Paiva, A.; Craveiro, R.; Aroso, I.; Martins, M.; Reis, R. L.; Duarte, A. R. C. Natural Deep Eutectic Solvents – Solvents for the 21st Century. ACS Sustain. Chem. Eng. 2014, 2(5), 1063–1071. DOI: 10.1021/sc500096j.
   Web of Science ®Google Scholar
• Abbott, A. P.; Ahmed, E. I.; Prasad, K.; Qader, I. B.; Ryder, K. S. Liquid Pharmaceuticals Formulation by Eutectic Formation. Fluid Ph. Equilibria. 2017, 448, 2–8. DOI: 10.1016/j.fluid.2017.05.009.
   Web of Science ®Google Scholar
• Rahman, M. S.; Roy, R.; Jadhav, B.; Hossain, M. N.; Halim, M. A.; Raynie, D. E. F. Structure, and Applications of Therapeutic and Amino Acid-Based Deep Eutectic Solvents: An Overview. J. Mol. Liq. 2021, 321, 114745. DOI: 10.1016/j.molliq.2020.114745.
   Web of Science ®Google Scholar
• Mecerreyes, D.; Porcarelli, L. 8 - Green Electrolyte-Based Organic Electronic Devices. In Sustainable Strategies in Organic Electronics; Marrocchi A., Ed. Woodhead Publishing Series: India, 2022; pp 281–295.
   Google Scholar
• Pedro, S. N.; Freire, M. G.; Freire, C. S. R.; Silvestre, A. J. D. Deep Eutectic Solvents Comprising Active Pharmaceutical Ingredients in the Development of Drug Delivery Systems. Expert Opin. Drug Deliv. 2019, 16(5), 497–506. DOI: 10.1080/17425247.2019.1604680.
   PubMed Web of Science ®Google Scholar
• Li, D. Natural Deep Eutectic Solvents in Phytonutrient Extraction and Other Applications. Front Plant Sci. 2022, 13, 1004332. DOI: 10.3389/fpls.2022.1004332.
   PubMed Web of Science ®Google Scholar
• Dai, Y.; Witkamp, G.-J.; Verpoorte, R.; Choi, Y. H. Tailoring Properties of Natural Deep Eutectic Solvents with Water to Facilitate Their Applications. Food Chem. 2015, 187, 14–19. DOI: 10.1016/j.foodchem.2015.03.123.
   PubMed Web of Science ®Google Scholar
• Le, N. T.; Hoang, N. T.; Van, V. T. T.; Nguyen, T. P. D.; Chau, N. H. T.; Le, N. T. N.; Le, H. B. T.; Phung, H. T.; Nguyen, H. T.; Nguyen, H. M. Extraction of Curcumin from Turmeric Residue (Curcuma Longa L.) Using Deep Eutectic Solvents and Surfactant Solvents. Anal. Methods. 2022, 14(8), 850–858. DOI: 10.1039/D1AY02152D.
   PubMed Web of Science ®Google Scholar
• Hsieh, Y.-H.; Li, Y.; Pan, Z.; Chen, Z.; Lu, J.; Yuan, J.; Zhu, Z.; Zhang, J. Ultrasonication-Assisted Synthesis of Alcohol-Based Deep Eutectic Solvents for Extraction of Active Compounds from Ginger. Ultrason Sonochem. 2020, 63, 104915. DOI: 10.1016/j.ultsonch.2019.104915.
   PubMed Web of Science ®Google Scholar
• Katryniok, B.; Paul, S.; Bellière-Baca, V.; Rey, P.; Dumeignil, F. Glycerol Dehydration to Acrolein in the Context of New Uses of Glycerol. Green Chem. 2010, 12(12), 2079–2098. DOI: 10.1039/c0gc00307g.
   Web of Science ®Google Scholar
• Isci, A.; Kaltschmitt, M. Recovery and Recycling of Deep Eutectic Solvents in Biomass Conversions: A Review. Biomass Conv. Bioref. 2022, 12(S1), 197–226. DOI: 10.1007/s13399-021-01860-9.
   Google Scholar
• Xu, M.; Ran, L.; Chen, N.; Fan, X.; Ren, D.; Yi, L. Polarity-Dependent Extraction of Flavonoids from Citrus Peel Waste Using a Tailor-Made Deep Eutectic Solvent. Food Chem. 2019, 297, 124970. DOI: 10.1016/j.foodchem.2019.124970.
   PubMed Web of Science ®Google Scholar
• Della Posta, S.; Gallo, V.; Gentili, A.; Fanali, C. Strategies for the Recovery of Bioactive Molecules from Deep Eutectic Solvents Extracts. TrAc Trends Anal. Chem. 2022, 157, 116798. DOI: 10.1016/j.trac.2022.116798.
   Web of Science ®Google Scholar
• Doldolova, K.; Bener, M.; Lalikoğlu, M.; Aşçı, Y. S.; Arat, R.; Apak, R. Optimization and Modeling of Microwave-Assisted Extraction of Curcumin and Antioxidant Compounds from Turmeric by Using Natural Deep Eutectic Solvents. Food Chem. 2021, 353, 129337. DOI: 10.1016/j.foodchem.2021.129337.
   PubMed Web of Science ®Google Scholar
• Liu, G.; Feng, S.; Sui, M.; Chen, B.; Sun, P. Extraction and Identification of Steroidal Saponins from Polygonatum Cyrtonema Hua Using Natural Deep Eutectic Solvent‐Synergistic Quartz Sand‐Assisted Extraction Method. J. Sep. Sci. 2023, 46(7), 2200823. DOI: 10.1002/jssc.202200823.
   Web of Science ®Google Scholar
• Saffarionpour, S.; Sevillano, D. M.; Van Der Wielen, L. A. M.; Noordman, T. R.; Brouwer, E.; Ottens, M. Selective Adsorption of Flavor-Active Components on Hydrophobic Resins. J. Chromatogr. A. 2016, 1476, 25–34. DOI: 10.1016/j.chroma.2016.10.053.
   PubMed Web of Science ®Google Scholar
• Xia, G.-H.; Li, X.-H.; Jiang, Y. Deep Eutectic Solvents as Green Media for Flavonoids Extraction from the Rhizomes of Polygonatum Odoratum. Alex. Eng. J. 2021, 60(2), 1991–2000. DOI: 10.1016/j.aej.2020.12.008.
   Web of Science ®Google Scholar
• Ren, J.; Zheng, Y.; Lin, Z.; Han, X.; Liao, W. Macroporous Resin Purification and Characterization of Flavonoids from Platycladus Orientalis (L.) Franco and Their Effects on Macrophage Inflammatory Response. Food Funct. 2017, 8(1), 86–95. DOI: 10.1039/C6FO01474G.
   PubMed Web of Science ®Google Scholar
• Wang, X.; Su, J.; Chu, X.; Zhang, X.; Kan, Q.; Liu, R.; Fu, X. Adsorption and Desorption Characteristics of Total Flavonoids from Acanthopanax Senticosus on Macroporous Adsorption Resins. Molecules. 2021, 26(14), 4162. DOI: 10.3390/molecules26144162.
   PubMed Web of Science ®Google Scholar
• Liu, Y.; Zhang, Y.; Zhou, Y.; Feng, X. Anthocyanins in Different Food Matrices: Recent Updates on Extraction, Purification and Analysis Techniques. Crit. Rev. Anal. Chem. 2022, 1–32. DOI: 10.1080/10408347.2022.2116556.
   Web of Science ®Google Scholar
• Zhong, J.-L.; Muhammad, N.; Gu, Y.-C.; Yan, W.-D. A Simple and Efficient Method for Enrichment of Cocoa Polyphenols from Cocoa Bean Husks with Macroporous Resins Following a Scale-Up Separation. J. Food Eng. 2019, 243, 82–88. DOI: 10.1016/j.jfoodeng.2018.08.023.
   Web of Science ®Google Scholar
• Saffarionpour, S.; Ottens, M. Recent Advances in Techniques for Flavor Recovery in Liquid Food Processing. Food Eng. Rev. 2018, 10(2), 81–94. DOI: 10.1007/s12393-017-9172-8.
   Web of Science ®Google Scholar
• Khan, A. S.; Ibrahim, T. H.; Jabbar, N. A.; Khamis, M. I.; Nancarrow, P.; Mjalli, F. S. Ionic Liquids and Deep Eutectic Solvents for the Recovery of Phenolic Compounds: Effect of Ionic Liquids Structure and Process Parameters. R.S.C. Adv. 2021, 11(20), 12398–12422. DOI: 10.1039/D0RA10560K.
   PubMed Web of Science ®Google Scholar
• Prasada Rao, T.; Biju, V. M. SPECTROPHOTOMETRY | Organic Compounds. In Encyclopedia of Analytical Science; Elsevier: 2005; pp. 358–366. doi:10.1016/B0-12-369397-7/00721-4
   Google Scholar
• Melwanki, M. B.; Fuh, M.-R. Dispersive Liquid–Liquid Microextraction Combined with Semi-Automated In-Syringe Back Extraction as a New Approach for the Sample Preparation of Ionizable Organic Compounds Prior to Liquid Chromatography. J. Chromatogr. A. 2008, 1198-1199, 1–6. DOI: 10.1016/j.chroma.2008.05.007.
   PubMed Web of Science ®Google Scholar
• Jafari, Z.; Hadjmohammadi, M. R. Development of Magnetic Solid Phase Extraction Based on Magnetic Chitosan–Graphene Oxide Nanoparticles and Deep Eutectic Solvents for the Determination of Flavonoids by High Performance Liquid Chromatography. Anal. Methods. 2021, 13(48), 5821–5829. DOI: 10.1039/D1AY01530C.
   PubMed Web of Science ®Google Scholar
• Abu Hatab, F.; Ibrahim, O. A. Z.; Warrag, S. E. E.; Darwish, A. S.; Lemaoui, T.; Alam, M. M.; Alsufyani, T.; Jevtovic, V.; Jeon, B.-H.; Banat, F., et al. Solvent Regeneration Methods for Combined Dearomatization, Desulfurization, and Denitrogenation of Fuels Using Deep Eutectic Solvents. ACS Omega. 2023, 8(1), 626–635. DOI: 10.1021/acsomega.2c05776.
   PubMed Web of Science ®Google Scholar
• Galanakis, C. M. Recovery of High Added-Value Components from Food Wastes: Conventional, Emerging Technologies and Commercialized Applications. Trends Food Sci. Technol. 2012, 26(2), 68–87. DOI: 10.1016/j.tifs.2012.03.003.
   Web of Science ®Google Scholar
• Plaza, A.; Tapia, X.; Yañez, C.; Vilches, F.; Candia, O.; Cabezas, R.; Romero, J. Obtaining Hydroxytyrosol from Olive Mill Waste Using Deep Eutectic Solvents and Then Supercritical CO2. Waste Biomass. Valor. 2020, 11(11), 6273–6284. DOI: 10.1007/s12649-019-00836-1.
   Web of Science ®Google Scholar
• Chen, Y.; Mu, T. Application of Deep Eutectic Solvents in Biomass Pretreatment and Conversion. Green Energy. Environ. 2019, 4(2), 95–115. DOI: 10.1016/j.gee.2019.01.012.
   Google Scholar
• Pochivalov, A.; Cherkashina, K.; Sudarkin, A.; Osmolowsky, M.; Osmolovskaya, O.; Krekhova, F.; Nugbienyo, L.; Bulatov, A. Liquid-Liquid Microextraction with Hydrophobic Deep Eutectic Solvent Followed by Magnetic Phase Separation for Preconcentration of Antibiotics. Talanta. 2023, 252, 123868. DOI: 10.1016/j.talanta.2022.123868.
   PubMed Web of Science ®Google Scholar
• Wang, N.; Li, Q. Study on Extraction and Antioxidant Activity of Polysaccharides from Radix Bupleuri by Natural Deep Eutectic Solvents Combined with Ultrasound-Assisted Enzymolysis. Sustain. Chem. Pharm. 2022, 30, 100877. DOI: 10.1016/j.scp.2022.100877.
   Web of Science ®Google Scholar
• Mackowiak, A.; Galek, P.; Fic, K. Deep Eutectic Solvents for High‐Temperature Electrochemical Capacitors. Chem. Electrochem. 2021, 8(21), 4028–4037. DOI: 10.1002/celc.202100711.
   Google Scholar
• Sui, M.; Feng, S.; Liu, G.; Chen, B.; Li, Z.; Shao, P. Deep Eutectic Solvent on Extraction of Flavonoid Glycosides from Dendrobium Officinale and Rapid Identification with UPLC-Triple-TOF/MS. Food Chem. 2023, 401, 134054. DOI: 10.1016/j.foodchem.2022.134054.
   PubMed Web of Science ®Google Scholar
• Hao, C.; Chen, L.; Dong, H.; Xing, W.; Xue, F.; Cheng, Y. Extraction of Flavonoids from Scutellariae Radix Using Ultrasound-Assisted Deep Eutectic Solvents and Evaluation of Their Anti-Inflammatory Activities. ACS Omega. 2020, 5(36), 23140–23147. DOI: https://doi.org/10.1021/acsomega.0c02898.
   PubMed Web of Science ®Google Scholar
• Nazir, F.; Nazir, A.; Javed, S.; Abid, H. A. Synthesis and Characterization of Natural Deep Eutectic Solvents as Green Extractants for Isolation of Bioactive Flavonoids from Amaranthus Viridis. Sustain. Chem. Pharm. 2023, 33, 101058. DOI: 10.1016/j.scp.2023.101058.
   Web of Science ®Google Scholar
• Bajkacz, S.; Adamek, J. Development of a Method Based on Natural Deep Eutectic Solvents for Extraction of Flavonoids from Food Samples. Food Anal. Methods 2018. Food Anal. Methods. 2018, 11(5), 1330–1344. DOI: https://doi.org/10.1007/s12161-017-1118-5.
   Web of Science ®Google Scholar
• Yu, Q.; Wang, F.; Jian, Y.; Chernyshev, V. M.; Zhang, Y.; Wang, Z.; Yuan, Z.; Chen, X. Extraction of Flavonoids from Glycyrrhiza Residues Using Deep Eutectic Solvents and Its Molecular Mechanism. J. Mol. Liq. 2022, 363, 119848. DOI: 10.1016/j.molliq.2022.119848.
   Web of Science ®Google Scholar
• Lin, S.; Meng, X.; Tan, C.; Tong, Y.; Wan, M.; Wang, M.; Zhao, Y.; Deng, H.; Kong, Y.; Ma, Y. Composition and Antioxidant Activity of Anthocyanins from Aronia Melanocarpa Extracted Using an Ultrasonic-Microwave-Assisted Natural Deep Eutectic Solvent Extraction Method. Ultrason Sonochem. 2022, 89, 106102. DOI: 10.1016/j.ultsonch.2022.106102.
   PubMed Web of Science ®Google Scholar
• Sang, J.; Liu, K.; Ma, Q.; Li, B.; Li, C. Combination of a Deep Eutectic Solvent and Macroporous Resin for Green Recovery of Anthocyanins from Nitraria Tangutorun Bobr. Fruit. Sep. Sci. Technol. 2019, 54(18), 3082–3090. DOI: 10.1080/01496395.2018.1559190.
   Web of Science ®Google Scholar
• Sang, J.; Li, B.; Huang, Y.; Ma, Q.; Liu, K.; Li, C. Deep Eutectic Solvent-Based Extraction Coupled with Green Two-Dimensional HPLC-DAD-ESI-MS/MS for the Determination of Anthocyanins from Lycium Ruthenicum Murr. Fruit. Anal. Methods. 2018, 10(10), 1247–1257. DOI: 10.1039/C8AY00101D.
   Web of Science ®Google Scholar
• Kongpol, K.; Sermkaew, N.; Makkliang, F.; Khongphan, S.; Chuaboon, L.; Sakdamas, A.; Sakamoto, S.; Putalun, W.; Yusakul, G. Extraction of Curcuminoids and Ar-Turmerone from Turmeric (Curcuma Longa L.) Using Hydrophobic Deep Eutectic Solvents (HDESs) and Application as HDES-Based Microemulsions. Food Chem. 2022, 396, 133728. DOI: 10.1016/j.foodchem.2022.133728.
   PubMed Web of Science ®Google Scholar
• Alioui, O.; Sobhi, W.; Tiecco, M.; Alnashef, I. M.; Attoui, A.; Boudechicha, A.; Kumar Yadav, K.; Fallatah, A. M.; Elboughdiri, N.; Jeon, B.-H., et al. Theoretical and Experimental Evidence for the Use of Natural Deep Eutectic Solvents to Increase the Solubility and Extractability of Curcumin. J. Mol. Liq. 2022, 359, 119149. DOI: 10.1016/j.molliq.2022.119149.
   Web of Science ®Google Scholar
• Huber, V.; Hioe, J.; Touraud, D.; Kunz, W. Uncovering the Curcumin Solubilization Ability of Selected Natural Deep Eutectic Solvents Based on Quaternary Ammonium Compounds. J. Mol. Liq. 2022, 361, 119661. DOI: 10.1016/j.molliq.2022.119661.
   Web of Science ®Google Scholar
• Dias Ribeiro, B.; Zarur Coelho, M. A.; Marrucho, I. M. Extraction of Saponins from Sisal (Agave Sisalana) and Juá (Ziziphus Joazeiro) with Cholinium-Based Ionic Liquids and Deep Eutectic Solvents. Eur. Food Res. Technol. 2013, 237(6), 965–975. DOI: 10.1007/s00217-013-2068-9.
   Web of Science ®Google Scholar
• Tang, Y.; He, X.; Sun, J.; Liu, G.; Li, C.; Li, L.; Sheng, J.; Zhou, Z.; Xin, M.; Ling, D., et al. Comprehensive Evaluation on Tailor-Made Deep Eutectic Solvents (DESs) in Extracting Tea Saponins from Seed Pomace of Camellia Oleifera Abel. Food Chem. 2021, 342, 128243. DOI: 10.1016/j.foodchem.2020.128243.
   PubMed Web of Science ®Google Scholar
• Petrochenko, A. A.; Orlova, A.; Frolova, N.; Serebryakov, E. B.; Soboleva, A.; Flisyuk, E. V.; Frolov, A.; Shikov, A. N. Natural Deep Eutectic Solvents for the Extraction of Triterpene Saponins from Aralia Elata Var. Mandshurica (Rupr. & Maxim.) J. Wen. Molecules. 2023, 28(8), 3614. DOI: 10.3390/molecules28083614.
   PubMed Web of Science ®Google Scholar
• Xu, W.; Chu, K.; Li, H.; Zhang, Y.; Zheng, H.; Chen, R.; Chen, L. Ionic Liquid-Based Microwave-Assisted Extraction of Flavonoids from Bauhinia Championii (Benth.) Benth. Molecules. 2012, 17(12), 14323–14335. DOI: 10.3390/molecules171214323.
   PubMed Web of Science ®Google Scholar
• Chen, Y.; Yu, D.; Chen, W.; Fu, L.; Mu, T. Water Absorption by Deep Eutectic Solvents. Phys. Chem. Chem. Phys. 2019, 21(5), 2601–2610. DOI: 10.1039/C8CP07383J.
   PubMed Web of Science ®Google Scholar
• Kivelä, H.; Salomäki, M.; Vainikka, P.; Mäkilä, E.; Poletti, F.; Ruggeri, S.; Terzi, F.; Lukkari, J. Effect of Water on a Hydrophobic Deep Eutectic Solvent. J. Phys. Chem B. 2022, 126(2), 513–527. DOI: 10.1021/acs.jpcb.1c08170.
   PubMed Web of Science ®Google Scholar
• Deep Eutectic Solvents for Medicine, Gas Solubilization and Extraction of Natural Substances. In Environmental Chemistry for a Sustainable World; Fourmentin, S., Costa Gomes, M., Lichtfouse, E., Eds.; Springer International Publishing: Cham, 2021; Vol. 56. DOI: 10.1007/978-3-030-53069-3.
   Google Scholar
• Gabriele, F.; Chiarini, M.; Germani, R.; Tiecco, M.; Spreti, N. Effect of Water Addition on Choline Chloride/Glycol Deep Eutectic Solvents: Characterization of Their Structural and Physicochemical Properties. J. Mol. Liq. 2019, 291, 111301. DOI: 10.1016/j.molliq.2019.111301.
   Web of Science ®Google Scholar
• Omar, K. A.; Sadeghi, R. Physicochemical Properties of Deep Eutectic Solvents: A Review. J. Mol. Liq. 2022, 360, 119524. DOI: 10.1016/j.molliq.2022.119524.
   Web of Science ®Google Scholar
• Taco, V.; Savarino, P.; Benali, S.; Villacrés, E.; Raquez, J.-M.; Gerbaux, P.; Duez, P.; Nachtergael, A. Deep Eutectic Solvents for the Extraction and Stabilization of Ecuadorian Quinoa (Chenopodium Quinoa Willd.) Saponins. J. Clean. Prod. 2022, 363, 132609. DOI: 10.1016/j.jclepro.2022.132609.
   Web of Science ®Google Scholar
• Lee, J. W.; Park, H. Y.; Park, J. Enhanced Extraction Efficiency of Flavonoids from Pyrus Ussuriensis Leaves with Deep Eutectic Solvents. Molecules. 2022, 27(9), 2798. DOI: 10.3390/molecules27092798.
   PubMed Web of Science ®Google Scholar
• Cunha, S. C.; Fernandes, J. O. Extraction Techniques with Deep Eutectic Solvents. TrAc Trends Anal. Chem. 2018, 105, 225–239. DOI: 10.1016/j.trac.2018.05.001.
   Web of Science ®Google Scholar
• Mansinhos, I.; Gonçalves, S.; Rodríguez-Solana, R.; Ordóñez-Díaz, J. L.; Moreno-Rojas, J. M.; Romano, A. Ultrasonic-Assisted Extraction and Natural Deep Eutectic Solvents Combination: A Green Strategy to Improve the Recovery of Phenolic Compounds from Lavandula Pedunculata Subsp. Lusitanica (Chaytor) Franco. Antioxidants. 2021, 10(4), 582. DOI: 10.3390/antiox10040582.
   Web of Science ®Google Scholar
• Tiwari, B. K. Ultrasound: A Clean, Green Extraction Technology. TrAc Trends Anal. Chem. 2015, 71, 100–109. DOI: 10.1016/j.trac.2015.04.013.
   Web of Science ®Google Scholar
• Kumar, K.; Srivastav, S.; Sharanagat, V. S. Ultrasound Assisted Extraction (UAE) of Bioactive Compounds from Fruit and Vegetable Processing By-Products: A Review. Ultrason. Sonochem. 2021, 70, 105325. DOI: 10.1016/j.ultsonch.2020.105325.
   PubMed Web of Science ®Google Scholar
• Panda, D.; Manickam, S. Cavitation Technology—The Future of Greener Extraction Method: A Review on the Extraction of Natural Products and Process Intensification Mechanism and Perspectives. Appl. Sci. 2019, 9(4), 766. DOI: 10.3390/app9040766.
   Google Scholar
• Boateng, I. D. Recent Processing of Fruits and Vegetables Using Emerging Thermal and Non-Thermal Technologies. A Critical Review of Their Potentialities and Limitations on Bioactives, Structure, and Drying Performance. Critical Reviews In Food Sci. & Nutrit. 2022, 1–35. DOI: 10.1080/10408398.2022.2140121.
   PubMed Web of Science ®Google Scholar
• Rojas, R.; Castro-López, C.; Sánchez-Alejo, E. J.; Niño-Medina, G.; Martínez-Ávila, G. C. G. Phenolic Compound Recovery from Grape Fruit and By- Products: An Overview of Extraction Methods. In Grape and Wine Biotechnology; Morata, A. Loira, I., Eds.; InTech, 2016. DOI: 10.5772/64821.
   Google Scholar
• Xi, J. Ultrahigh Pressure Extraction of Bioactive Compounds from Plants—A Review. Crit. Rev. Food Sci. Nutr. 2017, 57(6), 1097–1106. DOI: 10.1080/10408398.2013.874327.
   PubMed Web of Science ®Google Scholar
• Routray, W.; Orsat, V. Microwave-Assisted Extraction of Flavonoids: A Review. Food Bioprocess. Technol. 2012, 5(2), 409–424. DOI: 10.1007/s11947-011-0573-z.
   Web of Science ®Google Scholar
• Ekezie, F.-G. C.; Sun, D.-W.; Cheng, J.-H. Acceleration of Microwave-Assisted Extraction Processes of Food Components by Integrating Technologies and Applying Emerging Solvents: A Review of Latest Developments. Trends Food Sci. Technol. 2017, 67, 160–172. DOI: 10.1016/j.tifs.2017.06.006.
   Web of Science ®Google Scholar
• Chan, C.-H.; Yusoff, R.; Ngoh, G.-C.; Kung, F. W.-L. Microwave-Assisted Extractions of Active Ingredients from Plants. J. Chromatogr. A. 2011, 1218(37), 6213–6225. DOI: 10.1016/j.chroma.2011.07.040.
   PubMed Web of Science ®Google Scholar
• Liu, W.; Fu, Y.; Zu, Y.; Kong, Y.; Zhang, L.; Zu, B.; Efferth, T. Negative-Pressure Cavitation Extraction for the Determination of Flavonoids in Pigeon Pea Leaves by Liquid Chromatography–Tandem Mass Spectrometry. J. Chromatogr. A. 2009, 1216(18), 3841–3850. DOI: 10.1016/j.chroma.2009.02.073.
   PubMed Web of Science ®Google Scholar
• Cui, Q.; Liu, J.-Z.; Yu, L.; Gao, M.-Z.; Wang, L.-T.; Wang, W.; Zhao, X.-H.; Fu, Y.-J.; Jiang, J.-C. Experimental and Simulative Studies on the Implications of Natural and Green Surfactant for Extracting Flavonoids. J. Clean. Prod. 2020, 274, 122652. DOI: 10.1016/j.jclepro.2020.122652.
   Web of Science ®Google Scholar
• Huang, H.-W.; Hsu, C.-P.; Yang, B. B.; Wang, C.-Y. Advances in the Extraction of Natural Ingredients by High Pressure Extraction Technology. Trends Food Sci. Technol. 2013, 33(1), 54–62. DOI: 10.1016/j.tifs.2013.07.001.
   Web of Science ®Google Scholar
• Jun, X.; Deji, S.; Ye, L.; Rui, Z. Micromechanism of Ultrahigh Pressure Extraction of Active Ingredients from Green Tea Leaves. Food Control. 2011, 22(8), 1473–1476. DOI: 10.1016/j.foodcont.2011.03.008.
   Web of Science ®Google Scholar
• Chen, R.; Meng, F.; Zhang, S.; Liu, Z. Effects of Ultrahigh Pressure Extraction Conditions on Yields and Antioxidant Activity of Ginsenoside from Ginseng. Sep. Purif. Technol. 2009, 66(2), 340–346. DOI: 10.1016/j.seppur.2008.12.026.
   Web of Science ®Google Scholar
• Sammani, M. S.; Clavijo, S.; Cerdà, V. R. Recent, Advanced Sample Pretreatments and Analytical Methods for Flavonoids Determination in Different Samples. TrAc Trends Anal. Chem. 2021, 138, 116220. DOI: 10.1016/j.trac.2021.116220.
   Web of Science ®Google Scholar
• Xie, Z.; Sun, Y.; Lam, S.; Zhao, M.; Liang, Z.; Yu, X.; Yang, D.; Xu, X. Extraction and Isolation of Flavonoid Glycosides from Flos Sophorae Immaturus Using Ultrasonic-Assisted Extraction Followed by High-Speed Countercurrent Chromatography: Liquid Chromatography. J. Sep. Sci. 2014, 37(8), 957–965. DOI: 10.1002/jssc.201301340.
   PubMed Web of Science ®Google Scholar
• Zhang, H.; Xie, G.; Tian, M.; Pu, Q.; Qin, M. Optimization of the Ultrasonic-Assisted Extraction of Bioactive Flavonoids from Ampelopsis Grossedentata and Subsequent Separation and Purification of Two Flavonoid Aglycones by High-Speed Counter-Current Chromatography. Molecules 2016, 21 (8), 1096. 10.3390/molecules21081096.
   Google Scholar
• Xiao, X.; Si, X.; Tong, X.; Li, G. Preparation of Flavonoids and Diarylheptanoid from Alpinia Katsumadai Hayata by Microwave-Assisted Extraction and High-Speed Counter-Current Chromatography. Sep. Purif. Technol. 2011, 81(3), 265–269. DOI: 10.1016/j.seppur.2011.07.013.
   Web of Science ®Google Scholar
• Huang, L.; Cao, Y.; Chen, G. Purification of Quercetin in Anoectochilu Roxburghii (Wall) Lindl Using UMAE by High-Speed Counter-Current Chromatography and Subsequent Structure Identification. Sep. Purif. Technol. 2008, 64(1), 101–107. DOI: 10.1016/j.seppur.2008.07.021.
   Web of Science ®Google Scholar
• Zhang, Y.; Wang, B.; Jia, Z.; Scarlett, C. J.; Sheng, Z. Adsorption/Desorption Characteristics and Enrichment of Quercetin, Luteolin and Apigenin from Flos Populi Using Macroporous Resin. Rev. Bras. Farmacogn. 2019, 29(1), 69–76. DOI: 10.1016/j.bjp.2018.09.002.
   Google Scholar
• Luo, H.; Liu, H.; Cao, Y.; Xu, D.; Mao, Z.; Mou, Y.; Meng, J.; Lai, D.; Liu, Y.; Zhou, L. Enhanced Production of Botrallin and TMC-264 with in situ Macroporous Resin Adsorption in Mycelial Liquid Culture of the Endophytic Fungus Hyalodendriella Sp. Ponipodef12. Molecules. 2014, 19(9), 14221–14234. DOI: 10.3390/molecules190914221.
   PubMed Web of Science ®Google Scholar
• Gong, L.; Wu, Y.; Qiu, X.; Xin, X.; An, F.; Guo, M. Adsorption Characteristics and Enrichment of Emodin from Marine-Derived Aspergillus Flavipes HN4-13 Extract by Macroporous Resin XAD-16. Mar. Drugs. 2022, 20(4), 231. DOI: 10.3390/md20040231.
   PubMed Web of Science ®Google Scholar