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Neurological Research
A Journal of Progress in Neurosurgery, Neurology and Neurosciences
Volume 39, 2017 - Issue 10
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Original Research Paper

Effects of neuroserpin on clinical outcomes and inflammatory markers in Chinese patients with acute ischemic stroke

, ORCID Icon, , , , , , , , & show all
Pages 862-868 | Received 10 May 2017, Accepted 14 Jul 2017, Published online: 24 Jul 2017

References

  • Hastings GA, Coleman TA, Haudenschild CC, et al. Neuroserpin, a brain-associated inhibitor of tissue plasminogen activator is localized primarily in neurons Implications for the regulation of motor learning and neuronal survival. J Biol Chem. 1997;272:33062–33067.10.1074/jbc.272.52.33062
  • Krueger SR, Ghisu G-P, Cinelli P, et al. Expression of neuroserpin, an inhibitor of tissue plasminogen activator, in the developing and adult nervous system of the mouse. J neurosci. 1997;17:8984–8996.
  • Osterwalder T, Contartese J, Stoeckli E, et al. Neuroserpin, an axonally secreted serine protease inhibitor. EMBO j. 1996;15:2944.
  • Yepes M, Sandkvist M, Wong MK, et al. Neuroserpin reduces cerebral infarct volume and protects neurons from ischemia-induced apoptosis. Blood. 2000;96:569–576.
  • Cinelli P, Madani R, Tsuzuki N, et al. Neuroserpin, a neuroprotective factor in focal ischemic stroke. Mol Cell Neurosci. 2001;18:443–457. Epub 2002/04/02.10.1006/mcne.2001.1028
  • Zhang Z, Zhang L, Yepes M, et al. Adjuvant treatment with neuroserpin increases the therapeutic window for tissue-type plasminogen activator administration in a rat model of embolic stroke. Circulation. 2002;106:740–745.10.1161/01.CIR.0000023942.10849.41
  • Lebeurrier N, Liot G, Lopez-Atalaya JP, et al. The brain-specific tissue-type plasminogen activator inhibitor, neuroserpin, protects neurons against excitotoxicity both in vitro and in vivo. Mol Cell Neurosci. 2005;30:552–558. Epub 2005/10/08.10.1016/j.mcn.2005.09.005
  • Lebeurrier N, Launay S, Macrez R, et al. Anti-Mullerian-hormone-dependent regulation of the brain serine-protease inhibitor neuroserpin. J Cell Sci. 2008;121:3357–3365. Epub 2008/09/18.10.1242/jcs.031872
  • Wu J, Echeverry R, Guzman J, et al. Neuroserpin protects neurons from ischemia-induced plasmin-mediated cell death independently of tissue-type plasminogen activator inhibition. Am J Pathol. 2010;177:2576–2584. Epub 2010/09/25.10.2353/ajpath.2010.100466
  • Gelderblom M, Neumann M, Ludewig P, et al. Deficiency in serine protease inhibitor neuroserpin exacerbates ischemic brain injury by increased postischemic inflammation. PLoS One. 2013;8:e63118. Epub 2013/05/10.10.1371/journal.pone.0063118
  • Liang W, Chuan-Zhen L, Qiang D, et al. Reductions in mRNA of the neuroprotective agent, neuroserpin, after cerebral ischemia/reperfusion in diabetic rats. Brain Res. 2004;1015:175–180. Epub 2004/06/30.10.1016/j.brainres.2004.04.053
  • Wang L, Zhang Y, Asakawa T, et al. Neuroprotective Effect of Neuroserpin in Oxygen-Glucose Deprivation-and Reoxygenation-Treated Rat Astrocytes In Vitro. PLoS One. 2015;10:e0123932.10.1371/journal.pone.0123932
  • Yang X, Asakawa T, Han S, et al. Neuroserpin protects rat neurons and microglia-mediated inflammatory response against oxygen-glucose deprivation- and reoxygenation treatments in an in vitro study. Cell Physiol Biochem. 2016;38:1472–1482.10.1159/000443089
  • Rodriguez-Gonzalez R, Millan M, Sobrino T, et al. The natural tissue plasminogen activator inhibitor neuroserpin and acute ischaemic stroke outcome. Thromb Haemost. 2011;105:421–429. Epub 2010/12/22.
  • Rodriguez-Gonzalez R, Sobrino T, Rodriguez-Yanez M, et al. Association between neuroserpin and molecular markers of brain damage in patients with acute ischemic stroke. J Transl Med. 2011;9:58. Epub 2011/05/17.10.1186/1479-5876-9-58
  • 2010 CfetCGftEMoPwAIS. Chinese Guidelines for the Early Management of Patients with Acute Ischemic Stroke 2010. Chin J Neurol. 2010;43:146–153.
  • Vogt G, Laage R, Shuaib A, et al. Initial lesion volume is an independent predictor of clinical stroke outcome at day 90 an analysis of the virtual international stroke trials archive (VISTA) database. Stroke. 2012;43:1266–1272.10.1161/STROKEAHA.111.646570
  • Brott T, Adams H, Olinger CP, et al. Measurements of acute cerebral infarction: a clinical examination scale. Stroke. 1989;20:864–870.10.1161/01.STR.20.7.864
  • Lyden PD, Hantson L. Assessment scales for the evaluation of stroke patients. J Stroke Cerebrovascular Diseases. 1998;7:113–127.10.1016/S1052-3057(98)80138-9
  • Asakawa T, Fang H, Sugiyama K, et al. Human behavioral assessments in current research of Parkinson’s disease. Neurosci Biobehav Rev. 2016;68:741–772.10.1016/j.neubiorev.2016.06.036
  • Asakawa T, Fang H, Sugiyama K, et al. Animal behavioral assessments in current research of Parkinson’s disease. Neurosci Biobehav Rev. 2016;65:63–94.10.1016/j.neubiorev.2016.03.016
  • Fang X, Namba H, Akamine S, et al. Methylenetetrahydrofolate reductase gene polymorphisms in patients with cerebral hemorrhage. Neurol Res. 2005;27:73–76.10.1179/016164105X18313
  • Rodriguez-Gonzalez R, Agulla J, Perez-Mato M, et al. Neuroprotective effect of neuroserpin in rat primary cortical cultures after oxygen and glucose deprivation and tPA. Neurochem Int. 2011;58:337–343 . Epub 2010/12/18.10.1016/j.neuint.2010.12.006
  • Yepes M, Lawrence DA. Neuroserpin: a selective inhibitor of tissue-type plasminogen activator in the central nervous system. Thrombosis Haemostasis-Stuttgart. 2004;91:457–464.
  • Dziedzic T. Systemic inflammation as a therapeutic target in acute ischemic stroke. Expert Rev Neurother. 2015;15:523–531.10.1586/14737175.2015.1035712
  • Beamer NB, Coull BM, Clark WM, et al. Interleukin-6 and interleukin-1 receptor antagonist in acute stroke. Annals Neurol. 1995;37:800–805.10.1002/ana.410370614
  • Acalovschi D, Wiest T, Hartmann M, et al. Multiple levels of regulation of the interleukin-6 system in stroke. Stroke. 2003;34:1864–1869.10.1161/01.STR.0000079815.38626.44
  • Waje-Andreassen U, Kråkenes J, Ulvestad E, et al. IL-6: an early marker for outcome in acute ischemic stroke. Acta Neurol Scand. 2005;111:360–365.10.1111/ane.2005.111.issue-6
  • Audebert HJ, Rott MM, Eck T, et al. Systemic inflammatory response depends on initial stroke severity but is attenuated by successful thrombolysis. Stroke. 2004;35:2128–2133.10.1161/01.STR.0000137607.61697.77
  • Vila N, Castillo J, Dávalos A, et al. Proinflammatory cytokines and early neurological worsening in ischemic stroke. Stroke. 2000;31:2325–2329.10.1161/01.STR.31.10.2325

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