Rufinamide pretreatment attenuates ischemia-reperfusion injury in the gerbil hippocampus

References

• Globus MY , Busto R , Martinez E , et al . Comparative effect of transient global ischemia on extracellular levels of glutamate, glycine, and gamma-aminobutyric acid in vulnerable and nonvulnerable brain regions in the rat. J Neurochem. 1991;57:470–478.10.1111/jnc.1991.57.issue-2
   PubMed Web of Science ®Google Scholar
• Murakami K , Kondo T , Kawase M , et al . The development of a new mouse model of global ischemia: focus on the relationships between ischemia duration, anesthesia, cerebral vasculature, and neuronal injury following global ischemia in mice. Brain Res. 1998;780:304–310.10.1016/S0006-8993(97)01217-1
   PubMed Web of Science ®Google Scholar
• Pulsinelli WA. Selective neuronal vulnerability: morphological and molecular characteristics. Prog Brain Res. 1985;63:29–37.10.1016/S0079-6123(08)61973-1
   PubMed Web of Science ®Google Scholar
• Yu DK , Yoo KY , Shin BN , et al . Neuronal damage in hippocampal subregions induced by various durations of transient cerebral ischemia in gerbils using Fluoro-Jade B histofluorescence. Brain Res. 2012;1437:50–57.10.1016/j.brainres.2011.12.029
   PubMed Web of Science ®Google Scholar
• Kirino T . Delayed neuronal death in the gerbil hippocampus following ischemia. Brain Res. 1982;239:57–69.10.1016/0006-8993(82)90833-2
   PubMed Web of Science ®Google Scholar
• Lee JC , Park JH , Ahn JH , et al . New GABAergic neurogenesis in the hippocampal CA1 region of a gerbil model of long-term survival after transient cerebral ischemic injury. Brain Pathol. 2016;26:581–592.10.1111/bpa.2016.26.issue-5
   PubMed Web of Science ®Google Scholar
• Park JH , Shin BN , Ahn JH , et al . Ischemia-induced changes of PRAS40 and p-PRAS40 immunoreactivities in the gerbil hippocampal CA1 region after transient cerebral ischemia. Cell Mol Neurobiol. 2016;36:821–828.10.1007/s10571-015-0265-8
   PubMed Web of Science ®Google Scholar
• Calabresi P , Cupini LM , Centonze D , et al . Antiepileptic drugs as a possible neuroprotective strategy in brain ischemia. Ann Neurol. 2003;53:693–702.10.1002/(ISSN)1531-8249
   PubMed Web of Science ®Google Scholar
• Lee CH , Park JH , Yoo KY , et al . Pre- and post-treatments with escitalopram protect against experimental ischemic neuronal damage via regulation of BDNF expression and oxidative stress. Exp Neurol. 2011;229:450–459.10.1016/j.expneurol.2011.03.015
   PubMed Web of Science ®Google Scholar
• Park JH , Shin BN , Chen BH , et al . Neuroprotection and reduced gliosis by atomoxetine pretreatment in a gerbil model of transient cerebral ischemia. J Neurol Sci. 2015;359:373–380.10.1016/j.jns.2015.11.028
   PubMed Web of Science ®Google Scholar
• Arroyo S . Rufinamide. Neurotherapeutics. 2007;4:155–162.10.1016/j.nurt.2006.11.006
   PubMed Web of Science ®Google Scholar
• Suter MR , Kirschmann G , Laedermann CJ , et al . Rufinamide attenuates mechanical allodynia in a model of neuropathic pain in the mouse and stabilizes voltage-gated sodium channel inactivated state. Anesthesiology. 2013;118:160–172.10.1097/ALN.0b013e318278cade
   PubMed Web of Science ®Google Scholar
• Vohora D , Saraogi P , Yazdani MA , et al . Recent advances in adjunctive therapy for epilepsy: Focus on sodium channel blockers as third-generation antiepileptic drugs. Drugs Today (Barc). 2010;46:265–277.10.1358/dot.2010.46.4.1445795
   PubMed Web of Science ®Google Scholar
• Mantegazza M , Curia G , Biagini G , et al . Voltage-gated sodium channels as therapeutic targets in epilepsy and other neurological disorders. Lancet Neurol. 2010;9:413–424.10.1016/S1474-4422(10)70059-4
   PubMed Web of Science ®Google Scholar
• Ahn JY , Yan BC , Park JH , et al . Novel antiepileptic drug lacosamide exerts neuroprotective effects by decreasing glial activation in the hippocampus of a gerbil model of ischemic stroke. Exp Ther Med. 2015;10:2007–2014.
   PubMed Web of Science ®Google Scholar
• Minato H , Kikuta C , Fujitani B , et al . Protective effect of zonisamide, an antiepileptic drug, against transient focal cerebral ischemia with middle cerebral artery occlusion-reperfusion in rats. Epilepsia. 1997;38:975–980.10.1111/epi.1997.38.issue-9
   PubMed Web of Science ®Google Scholar
• White HS , Franklin MR , Kupferberg HJ , et al . The anticonvulsant profile of rufinamide (CGP 33101) in rodent seizure models. Epilepsia. 2008;49:1213–1220.10.1111/epi.2008.49.issue-7
   PubMed Web of Science ®Google Scholar
• Lee JC , Ahn JH , Lee DH , et al . Neuronal damage and gliosis in the somatosensory cortex induced by various durations of transient cerebral ischemia in gerbils. Brain Res. 2013;1510:78–88.10.1016/j.brainres.2013.03.008
   PubMed Web of Science ®Google Scholar
• Ha Park J , Yoo KY , Hye Kim I , et al . Hydroquinone strongly alleviates focal ischemic brain injury via blockage of blood-brain barrier disruption in rats. Toxicol Sci. 2016;154:430–441.10.1093/toxsci/kfw167
   PubMed Web of Science ®Google Scholar
• Choi HY , Park JH , Chen BH , et al . Increases of catalase and glutathione peroxidase expressions by lacosamide pretreatment contributes to neuroprotection against experimentally induced transient cerebral ischemia. Neurochem Res. 2016;41:2380–2390.10.1007/s11064-016-1951-8
   PubMed Web of Science ®Google Scholar
• Cuomo O , Rispoli V , Leo A , et al . The antiepileptic drug levetiracetam suppresses non-convulsive seizure activity and reduces ischemic brain damage in rats subjected to permanent middle cerebral artery occlusion. PLoS One. 2013;8:e80852.10.1371/journal.pone.0080852
   PubMed Web of Science ®Google Scholar
• Suda S , Katsura K , Kanamaru T , et al . Valproic acid attenuates ischemia-reperfusion injury in the rat brain through inhibition of oxidative stress and inflammation. Eur J Pharmacol. 2013;707:26–31.10.1016/j.ejphar.2013.03.020
   PubMed Web of Science ®Google Scholar
• Kuroiwa T , Bonnekoh P , Hossmann KA . Locomotor hyperactivity and hippocampal CA1 injury after transient forebrain ischemia of gerbils. Neurosci Lett. 1991;122:141–144.10.1016/0304-3940(91)90842-H
   PubMed Web of Science ®Google Scholar
• Andersen MB , Zimmer J , Sams-Dodd F . Postischemic hyperactivity in the Mongolian gerbil correlates with loss of hippocampal neurons. Behav Neurosci. 1997;111:1205–1216.10.1037/0735-7044.111.6.1205
   PubMed Web of Science ®Google Scholar
• Katoh A , Ishibashi C , Shiomi T , et al . Ischemia-induced irreversible deficit of memory function in gerbils. Brain Res. 1992;577:57–63.10.1016/0006-8993(92)90537-J
   PubMed Web of Science ®Google Scholar
• Das A , McDowell M , O’Dell CM , et al . Post-treatment with voltage-gated Na(+) channel blocker attenuates kainic acid-induced apoptosis in rat primary hippocampal neurons. Neurochem Res. 2010;35:2175–2183.10.1007/s11064-010-0321-1
   PubMed Web of Science ®Google Scholar
• Kato H , Takahashi A , Itoyama Y . Cell cycle protein expression in proliferating microglia and astrocytes following transient global cerebral ischemia in the rat. Brain Res Bull. 2003;60:215–221.10.1016/S0361-9230(03)00036-4
   PubMed Web of Science ®Google Scholar
• Lee TK , Park JH , Ahn JH , et al . Pretreated duloxetine protects hippocampal CA1 pyramidal neurons from ischemia-reperfusion injury through decreases of glial activation and oxidative stress. J Neurol Sci. 2016;370:229–236.10.1016/j.jns.2016.09.059
   PubMed Web of Science ®Google Scholar
• Amantea D , Certo M , Russo R , et al . Early reperfusion injury is associated to MMP2 and IL-1beta elevation in cortical neurons of rats subjected to middle cerebral artery occlusion. Neuroscience. 2014;277:755–763.10.1016/j.neuroscience.2014.07.064
   PubMed Web of Science ®Google Scholar
• Webster CM , Hokari M , McManus A , et al . Microglial P2Y12 deficiency/inhibition protects against brain ischemia. PLoS One. 2013;8:e70927.10.1371/journal.pone.0070927
   PubMed Web of Science ®Google Scholar
• Yan BC , Kim SK , Park JH , et al . Comparison of inflammatory cytokines changes in the hippocampal CA1 region between the young and adult gerbil after transient cerebral ischemia. Brain Res. 2012;1461:64–75.10.1016/j.brainres.2012.04.025
   PubMed Web of Science ®Google Scholar
• Wei R , Wang J , Xu Y , et al . Probenecid protects against cerebral ischemia/reperfusion injury by inhibiting lysosomal and inflammatory damage in rats. Neuroscience. 2015;301:168–177.10.1016/j.neuroscience.2015.05.070
   PubMed Web of Science ®Google Scholar
• Xiao Z , Ren P , Chao Y , et al . Protective role of isoflurane pretreatment in rats with focal cerebral ischemia and the underlying molecular mechanism. Mol Med Rep. 2015;12:675–683.
   PubMed Web of Science ®Google Scholar
• Mao X , Ji C , Sun C , et al . Topiramate attenuates cerebral ischemia/reperfusion injury in gerbils via activating GABAergic signaling and inhibiting astrogliosis. Neurochem Int. 2012;60:39–46.10.1016/j.neuint.2011.10.015
   PubMed Web of Science ®Google Scholar
• Kim HJ , Rowe M , Ren M , et al . Histone deacetylase inhibitors exhibit anti-inflammatory and neuroprotective effects in a rat permanent ischemic model of stroke: multiple mechanisms of action. J Pharmacol Exp Ther. 2007;321:892–901.10.1124/jpet.107.120188
   PubMed Web of Science ®Google Scholar