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Neurological Research
A Journal of Progress in Neurosurgery, Neurology and Neurosciences
Volume 39, 2017 - Issue 12
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Original Research Paper

Anterior thalamic nuclei deep brain stimulation reduces disruption of the blood–brain barrier, albumin extravasation, inflammation and apoptosis in kainic acid-induced epileptic rats

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Pages 1103-1113 | Received 29 May 2017, Accepted 08 Sep 2017, Published online: 18 Sep 2017

References

  • Sheinberg R, Heyman E, Dagan Z, et al. Correlation between efficacy of levetiracetam and serum levels among children with refractory epilepsy. Pediatr Neurol. 2015;52:624–628 . Epub 2015/03/21.10.1016/j.pediatrneurol.2015.01.012
  • López González FJ, Rodríguez Osorio X, Gil-Nagel Rein A, et al. Drug-resistant epilepsy: definition and treatment alternatives. Neurologia 2015;30:439–446. Epub 2014/07/01.10.1016/j.nrl.2014.04.012
  • Laxpati NG, Kasoff WS, Gross RE. Deep brain stimulation for the treatment of epilepsy: circuits, targets, and trials. Neurotherapeutics 2014;11:508–526 . Epub 2014/06/25.10.1007/s13311-014-0279-9
  • Salanova V, Witt T, Worth R, et al. Long-term efficacy and safety of thalamic stimulation for drug-resistant partial epilepsy. Neurology 2015;84:1017–1025 . Epub 2015/02/11.10.1212/WNL.0000000000001334
  • Shi L, Yang AC, Li JJ, et al. Favorable modulation in neurotransmitters: effects of chronic anterior thalamic nuclei stimulation observed in epileptic monkeys. Exp Neurol. 2015;265:94–101 . Epub 2015/01/18.10.1016/j.expneurol.2015.01.003
  • Yang AC, Shi L, Li LM, et al. Potential protective effects of chronic anterior thalamic nucleus stimulation on hippocampal neurons in epileptic monkeys. Brain Stimul. 2015;8:1049–1057 . Epub 2015/08/25.10.1016/j.brs.2015.07.041
  • Radzik I, Miziak B, Dudka J, et al. Prospects of epileptogenesis prevention. Pharmacol Rep. 2015;67:663–668 . Epub 2015/05/03.10.1016/j.pharep.2015.01.016
  • Gorter JA, van, Vliet EA, Aronica E, et al. Potential new antiepileptogenic targets indicated by microarray analysis in a rat model for temporal lobe epilepsy. J Neurosci. 2006;26:11083–11110 . Epub 2006/10/27.10.1523/JNEUROSCI.2766-06.2006
  • Matin N, Tabatabaie O, Falsaperla R, et al. Epilepsy and innate immune system: a possible immunogenic predisposition and related therapeutic implications. Hum Vaccin Immunother. 2015;11:2021–2029 . Epub 2015/08/12.10.1080/21645515.2015.1034921
  • George Paxinos CW. The rat brain in stereotaxic coordinates. 6th ed. Amsterdam: Elsevier; 2007.
  • Phelan KD, Shwe UT, Williams DK, et al. Pilocarpine-induced status epilepticus in mice: a comparison of spectral analysis of electroencephalogram and behavioral grading using the Racine scale. Epilepsy Res. 2015;117:90–96 . Epub 2015/10/04.10.1016/j.eplepsyres.2015.09.008
  • Baj G, Del Turco D, Schlaudraff J, et al. Regulation of the spatial code for BDNF mRNA isoforms in the rat hippocampus following pilocarpine-treatment: a systematic analysis using laser microdissection and quantitative real-time PCR. Hippocampus 2013;23:413–423 . Epub 2013/02/26.10.1002/hipo.v23.5
  • Fukushima A, Ogura Y, Furuta M, et al. Ketogenic diet does not impair spatial ability controlled by the hippocampus in male rats. Brain Res. 2015;1622:36–42 . Epub 2015/06/27.10.1016/j.brainres.2015.06.016
  • Villapol S, Wang Y, Adams M, et al. Smad3 deficiency increases cortical and hippocampal neuronal loss following traumatic brain injury. Exp Neurol. 2013;250:353–365 . Epub 2013/10/15.10.1016/j.expneurol.2013.10.008
  • Meng DW, Liu HG, Yang AC, et al. Stimulation of anterior thalamic nuclei protects against seizures and neuronal apoptosis in hippocampal CA3 region of kainic acid-induced epileptic rats. Chin Med J. 2016;129:960–966 . Epub 2016/04/12.
  • Zhvania MG, Ksovreli M, Japaridze NJ, et al. Ultrastructural changes to rat hippocampus in pentylenetetrazol- and kainic acid-induced status epilepticus: a study using electron microscopy. Micron 2015;74:22–29. Epub 2015/05/16.10.1016/j.micron.2015.03.015
  • Legido A, Katsetos CD. Experimental studies in epilepsy: immunologic and inflammatory mechanisms. Semin Pediatr Neurol. 2014;21:197–206 . Epub 2014/12/17.10.1016/j.spen.2014.10.001
  • Kim JE, Ryu HJ, Kang TC. P2X7 receptor activation ameliorates CA3 neuronal damage via a tumor necrosis factor-α-mediated pathway in the rat hippocampus following status epilepticus. J Neuroinflammation. 2011;8:62 . Epub 2011/06/03.10.1186/1742-2094-8-62
  • Ivens S, Kaufer D, Flores LP, et al. TGF-β receptor-mediated albumin uptake into astrocytes is involved in neocortical epileptogenesis. Brain 2007;130:535–547 . Epub 2006/11/24.10.1093/brain/awl317
  • Shin HJ, Kim H, Heo RW, et al. Tonicity-responsive enhancer binding protein haplodeficiency attenuates seizure severity and NF-κB-mediated neuroinflammation in kainic acid-induced seizures. Cell Death Differ. 2014;21:1095–1106 . Epub 2014/03/13.10.1038/cdd.2014.29
  • Oprica M, Eriksson C, Schultzberg M. Inflammatory mechanisms associated with brain damage induced by kainic acid with special reference to the interleukin-1 system. J Cell Mol Med. 2003;7:127–140 . Epub 2003/08/21.10.1111/jcmm.2003.7.issue-2
  • Chen YC, Zhu GY, Wang X, et al. Deep brain stimulation of the anterior nucleus of the thalamus reverses the gene expression of cytokines and their receptors as well as neuronal degeneration in epileptic rats. Brain Res. 2017;1657:304–311 . Epub 2016/12/29.10.1016/j.brainres.2016.12.020
  • Rahman S. Pathophysiology of mitochondrial disease causing epilepsy and status epilepticus. Epilepsy Behav. 2015;49:71–75 . Epub 2015/07/15.
  • Levy N, Milikovsky DZ, Baranauskas G, et al. Differential TGF-β Signaling in Glial Subsets Underlies IL-6–Mediated Epileptogenesis in Mice. J Immunol. 2015;195:1713–1722. Epub 2015/07/03.10.4049/jimmunol.1401446
  • Riazi K, Galic MA, Kuzmiski JB, et al. Microglial activation and TNFα production mediate altered CNS excitability following peripheral inflammation. Proc Natl Acad Sci. 2008;105:17151–17156 . Epub 2008/10/29.10.1073/pnas.0806682105
  • Gu Y, Dee CM, Shen J. Interaction of free radicals, matrix metalloproteinases and caveolin-1 impacts blood-brain barrier permeability. Front Biosci. 2011;S3:1216–1231 . Epub 2011/05/31.10.2741/222
  • Seiffert E, Dreier JP, Ivens S, et al. Lasting blood-brain barrier disruption induces epileptic focus in the rat somatosensory cortex. J Neurosci. 2004;24:7829–7836 . Epub 2004/09/10.10.1523/JNEUROSCI.1751-04.2004
  • Cacheaux LP, Ivens S, David Y, et al. Transcriptome profiling reveals TGF-β signaling involvement in epileptogenesis. J Neurosci. 2009;29:8927–8935 . Epub 2009/07/17.10.1523/JNEUROSCI.0430-09.2009
  • Ralay Ranaivo H, Wainwright MS. Albumin activates astrocytes and microglia through mitogen-activated protein kinase pathways. Brain Res. 2010;1313:222–231 . Epub 2009/12/08.10.1016/j.brainres.2009.11.063
  • Gan N, Yang L, Omran A, et al. Myoloid-related protein 8, an endogenous ligand of toll-like receptor 4, is involved in epileptogenesis of mesial temporal lobe epilepsy via activation of the nuclear factor-κB pathway in astrocytes. Mol Neurobiol. 2014;49:337–351 . Epub 2013/08/29.10.1007/s12035-013-8522-7
  • Bell RD, Winkler EA, Singh I, et al. Apolipoprotein E controls cerebrovascular integrity via cyclophilin A. Nature 2012;485:512–516 . Epub 2012/05/25.
  • Twele F, Tollner K, Brandt C, et al. Significant effects of sex, strain, and anesthesia in the intrahippocampal kainate mouse model of mesial temporal lobe epilepsy. Epilepsy Behav. 2016;55:47–56 . Epub 2016/01/07.

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