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Neurological Research
A Journal of Progress in Neurosurgery, Neurology and Neurosciences
Volume 45, 2023 - Issue 5
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Research Article

Investigation of therapeutic effects of calcium dobesilate in cerebral hypoxia/ reperfusion injury in rats

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Pages 472-487 | Received 22 Aug 2022, Accepted 12 Dec 2022, Published online: 22 Dec 2022

References

  • Nagahiro S, Uno M, Sato K, et al. Pathophysiology and treatment of cerebral ischemia. J Med Invest. 1998;45(1–4):57–70.
  • Widmer L, Biland L, Barras JP. Doxium 500 in chronic venous insufficiency: a double-blind placebo controlled multicentre study. Int Angiol. 1990;9(2):105–110.
  • Baricevic J. Does calcium dobesilate (doxium) improve the microcirculation and the musculovenous pump in patients with varicose veins? Vasa. 1980;9(3):240–245.
  • Brunet J, Farine JC, Garay RP, et al. Angioprotective action of calcium dobesilate against reactive oxygen species-induced capillary permeability in the rat. Eur J Pharmacol. 1998;358(3):213–220. DOI:10.1016/S0014-2999(98)00604-9
  • Angulo J, Peiró C, Romacho T, et al. Inhibition of vascular endothelial growth factor (VEGF)-induced endothelial proliferation, arterial relaxation, vascular permeability and angiogenesis by dobesilate. Eur J Pharmacol. 2011;667(1–3):153–159. DOI:10.1016/j.ejphar.2011.06.015
  • Casley-Smith JR. The effects of calcium dobesilate on acute lymphedema (with and without macrophages), and on burn edema. Lymphology. 1985;18(1):37–45.
  • Ruiz E, Lorente R, Tejerina T. Effects of calcium dobesilate on the synthesis of endothelium-dependent relaxing factors in rabbit isolated aorta. Br J Pharmacol. 1997;121(4):711–716.
  • Suschek C, Kolb H, Kolb-Bachofen V. Dobesilate enhances endothelial nitric oxide synthase-activity in macro- and microvascular endothelial cells. Br J Pharmacol. 1997;122(7):1502–1508.
  • Bozkurt AK, Konukoglu D, Ustundag N, et al. Calcium dobesilate ameliorates lung injury following lower limb ischemia/reperfusion. Drugs Exp Clin Res. 2002;28(4):127–132.
  • Cihan Ozbek I, Arslan C, Canturk E, et al. The effects of calcium dobesilate on the mechanical function of rat hearts. J Cardiovasc Surg (Torino). 2009;50(3):395–401.
  • Seker A, Bardakci O, Eryilmaz S, et al. Does calcium dobesilate protect against intestinal ischemia-reperfusion injury induced in rats? Eur Rev Med Pharmacol Sci. 2016;20(10):2168–2173.
  • Nair AB, Jacob S. A simple practice guide for dose conversion between animals and human. J Basic Clin Pharm. 2016;7(2):27–31.
  • Cetin C, Erdogan AM, Dincel GC, et al. Effects of sulphasalazine in cerebral ischemia reperfusion injury in rat. Arch Med Res. 2017;48(3):247–256. DOI:10.1016/j.arcmed.2017.06.004
  • Akkurt I, Cetin C, Erdogan AM, et al. Cerebral ischemia/reperfusion injury could be managed by using tramadol. Neurol Res. 2018;40(9):774–784. DOI:10.1080/01616412.2018.1477556
  • Hirsch FR, Varella-Garcia M, PA B Jr, et al. Epidermal growth factor receptor in non-small-cell lung carcinomas: correlation between gene copy number and protein expression and impact on prognosis. J Clin Oncol. 2003;21(20):3798–3807. DOI:10.1200/JCO.2003.11.069
  • Armstrong D, Al-Awadi F. Lipid peroxidation and retinopathy in streptozotocin-induced diabetes. Free Radic Biol Med. 1991;11(4):433–436.
  • Ceylan-Isik AF, Dong M, Zhang Y, et al. Cardiomyocyte-specific deletion of endothelin receptor a rescues aging-associated cardiac hypertrophy and contractile dysfunction: role of autophagy. Basic Res Cardiol. 2013;108(2):335. DOI:10.1007/s00395-013-0335-3
  • Doyle KP, Simon RP, Stenzel-Poore MP. Mechanisms of ischemic brain damage. Neuropharmacology. 2008;55(3):310–318.
  • Iadecola C, Anrather J. The immunology of stroke: from mechanisms to translation. Nat Med. 2011 7;17(7):796–808. DOI:10.1038/nm.2399.
  • Yamasaki Y, Matsuo Y, Zagorski J, et al. New therapeutic possibility of blocking cytokine-induced neutrophil chemoattractant on transient ischemic brain damage in rats. Brain Res. 1997;759(1):103–111. DOI:10.1016/S0006-8993(97)00251-5
  • Hu X, Li P, Guo Y, et al. Microglia/Macrophage polarization dynamics reveal a novel mechanism of injury expansion after focal cerebral ischemia. Stroke. 2012;43(11):3063–3070. DOI:10.1161/STROKEAHA.112.659656
  • Ito D, Tanaka K, Suzuki S, et al. Enhanced expression of Iba1, ionized calcium-binding adapter molecule 1, after transient focal cerebral ischemia in rat brain. Stroke. 2001 May;32(5):1208–1215.
  • Perego C, Fumagalli S, De Simoni MG. Temporal pattern of expression and colocalization of microglia/macrophage phenotype markers following brain ischemic injury in mice. J Neuroinflammation. 2011 10;8(1):174. DOI:10.1186/1742-2094-8-174.
  • Garcia JH, Liu KF, Relton JK. Interleukin-1 receptor antagonist decreases the number of necrotic neurons in rats with middle cerebral artery occlusion. Am J Pathol. 1995;147(5):1477–1486.
  • Relton JK, Martin D, Thompson RC, et al. Peripheral administration of Interleukin-1 receptor antagonist inhibits brain damage after focal cerebral ischemia in the rat. Exp Neurol. 1996;138(2):206–213. DOI:10.1006/exnr.1996.0059
  • Yamasaki Y, Matsuura N, Shozuhara H, et al. Interleukin-1 as a pathogenetic mediator of ischemic brain damage in rats. Stroke. 1995;26(4):676–681. DOI:10.1161/01.STR.26.4.676
  • Yamasaki Y, Shozuhara H, Onodera H, et al. Blocking of interleukin-1 activity is a beneficial approach to ischemia brain edema formation. Acta Neurochir Suppl (Wien). 1994;60:300–302.
  • Lu SC. Glutathione synthesis. Biochim Biophys Acta. 2013;1830(5):3143–3353.
  • Bazmandegan G, Fatemi I, Kaeidi A, et al. Calcium dobesilate prevents cisplatin-induced nephrotoxicity by modulating oxidative and histopathological changes in mice. Naunyn Schmiedebergs Arch Pharmacol. 2021;394(3):515–521. DOI:10.1007/s00210-020-01990-3
  • Cerrahoglu M, Taner Kurdal A, Iskesen I, et al. Calcium dobesilate reduces oxidative stress in cardiac surgery. J Cardiovasc Surg (Torino). 2009;50(5):695–701.
  • Unal Y, Tuncal S, Kosmaz K, et al. The effect of calcium dobesilate on liver damage in experimental obstructive jaundice. J Invest Surg. 2019;32(3):238–244. DOI:10.1080/08941939.2018.1451936
  • Jin T, Jiang L, Zhang X. Influence of lower extremity deep venous thrombosis in cerebral infarction on coagulation index and Thromboelastogram and its risk factors. J Healthc Eng. 2022;2022:2754727.
  • Bravata DM, Wells CK, Lo AC, et al. Processes of care associated with acute stroke outcomes. Arch Intern Med. 2010;170(9):804–810. DOI:10.1001/archinternmed.2010.92

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