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Original Articles

Meat Consumption, Heterocyclic Amines, NAT2, and the Risk of Breast Cancer

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Pages 36-46 | Received 18 Mar 2008, Accepted 09 Jul 2008, Published online: 30 Dec 2008

REFERENCES

  • Boyd , N F , Martin , L J , Noffel , M , Lockwood , G A and Trichler , D L . 1993 . A meta-analysis of studies of dietary fat and breast cancer risk . Br J Cancer , 68 : 627 – 636 .
  • Ronco , A , DeStefani , E , Mendilaharsu , M and Deneo-Pellegrini , H . 1996 . Meat, fat and risk of breast cancer: a case-control study from Uruguay . Int J Cancer , 65 : 328 – 331 .
  • Toniolo , P , Riboli , E , Shore , R E and Pasternack , B S . 1994 . Consumption of meat, animal products, protein, and fat and risk of breast cancer: a prospective cohort study in New York . Epidemiology , 5 : 391 – 397 .
  • Boyd , N F , Stone , J , Vogt , K N , Connelly , B S Martin , L J . 2003 . Dietary fat and breast cancer risk revisited: a meta-analysis of the published literature . Br J Cancer , 89 : 1672 – 1685 .
  • Steck , S E , Gaudet , M M , Eng , S M , Britton , J A Teitelbaum , S L . 2007 . Cooked meat and risk of breast cancer-lifetime versus recent dietary intake . Epidemiology , 18 : 373 – 382 .
  • Dai , Q , Shu , X O , Jin , F , Gao , Y T Ruan , Z X . 2002 . Consumption of animal foods, cooking methods, and risk of breast cancer . Cancer Epidemiol Biomarkers Prev , 11 : 801 – 808 .
  • Zheng , W , Gustafson , D R , Sinha , R , Cerhan , J R Moore , D . 1998 . Well-done meat intake and the risk of breast cancer . J Natl Cancer Inst , 90 : 1724 – 1729 .
  • Hermann , S , Linseisen , J and Chang-Claude , J . 2002 . Nutrition and breast cancer risk by age 50: a population-based case-control study in Germany . Nutr Cancer , 44 : 23 – 34 .
  • Cho , E , Chen , W Y , Hunter , D J , Stampfer , M J Colditz , G A . 2006 . Red meat intake and risk of breast cancer among premenopausal women . Arch Intern Med , 166 : 2253 – 2259 .
  • Egeberg , R , Olsen , A , Autrup , H , Christensen , J Stripp , C . 2008 . Meat consumption, N-acetyl transferase 1 and 2 polymorphism and risk of breast cancer in Danish postmenopausal women . Eur J Cancer Prev , 17 : 39 – 47 .
  • Taylor , E F , Burley , V J , Greenwood , D C and Cade , J E . 2007 . Meat consumption and risk of breast cancer in the UK Women's Cohort Study . Br J Cancer , 96 : 1139 – 1146 .
  • Missmer , S A , Smith-Warner , S A , Spiegelman , D , Yaun , S S Adami , H O . 2002 . Meat and dairy food consumption and breast cancer: a pooled analysis of cohort studies . Int J Epidemiol , 31 : 78 – 85 .
  • Snyderwine , E G . 1994 . Some perspective on the nutritional aspects of breast cancer research: food-derived heterocyclic amines as etiologic agents in human mammary cancer . Cancer , 74 : 1070 – 1077 .
  • Felton , J S , Knize , M G , Shen , N H , Andresen , B D Bjeldanes , L F . 1986 . Identification of the mutagens in cooked beef . Environ Health Perspect , 67 : 17 – 24 .
  • Sinha , R , Rothman , N , Brown , E D , Mark , S D Hoover , R N . 1994 . Pan-fried meat containing high levels of heterocyclic aromatic amines but low levels of polycyclic aromatic hydrocarbons induces cytochrome P4501A2 activity in humans . Cancer Res , 54 : 6154 – 6159 .
  • Sinha , R and Rothman , N . 1997 . Exposure assessment of heterocyclic amines (HCAs) in epidemiologic studies . Mutat Res , 376 : 195 – 202 .
  • Nagao , M , Ushijima , T , Wakabayashi , K , Ochiai , M Kushida , H . 1994 . Dietary carcinogens and mammary carcinogenesis: induction of rat mammary carcinomas by administration of heterocyclic amines in cooked foods . Cancer , 74 : 1063 – 1069 .
  • Ito , N , Hasegawa , R , Sano , M , Tamano , S Esumi , H . 1991 . A new colon and mammary carcinogen in cooked food, 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) . Carcinogenesis , 12 : 1503 – 1506 .
  • Snyderwine , E G , Venugopal , M and Yu , M . 2002 . Mammary gland carcinogenesis by food-derived heterocyclic amines and studies on the mechanisms of carcinogenesis of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) . Mutat Res , 506–507 : 145 – 152 .
  • Hasegawa , R , Sano , M , Tamano , S , Imaida , K Shirai , T . 1993 . Dose-dependence of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine (PhIP) carcinogenicity in rats . Carcinogenesis , 14 : 2553 – 2557 .
  • Deitz , A C , Zheng , W , Leff , M A , Gross , M Wen , W Q . 2000 . N-Acetyltransferase-2 genetic polymorphism, well-done meat intake, and breast cancer risk among postmenopausal women . Cancer Epidemiol Biomarkers Prev , 9 : 905 – 910 .
  • Gooderham , N J , Murray , S , Lynch , A M , Yadollahi-Farsani , M Zhao , K . 1997 . Assessing human risk to heterocyclic amines . Mutat Res , 376 : 53 – 60 .
  • Lynch , A M , Knize , M G , Boobis , A R , Gooderham , N J Davies , D S . 1992 . Intra- and inter-individual variability in systemic exposure in man to MeIQx and PhIP, carcinogens present in cooked beef . Cancer Res , 52 : 6216 – 6223 .
  • Hein , D . 2002 . Molecular genetics and function of NAT1 and NAT2: role in aromatic amine metabolism and carcinogenesis . Mutat Res , 506–507 : 65 – 77 .
  • Brockton , N , Little , J , Sharp , L and Cotton , S C . 2000 . N-acetyltransferase polymorphisms and colorectal cancer: a HuGE review . Am J Epidemiol , 151 : 846 – 861 .
  • Hirvonen , A . 1999 . Polymorphic NAT's and cancer predisposition. Chap. 20 . IARC Sci Publications , 148 : 251 – 270 .
  • Stone , E M , Williams , J A , Grover , P L , Gusterson , B A and Phillips , D H . 1998 . Interindividual variation in the metabolic activation of heterocyclic amines and their N-hydroxy derivatives in primary cultures of human mammary epithelial cells . Carcinogenesis , 19 : 873 – 879 .
  • Gertig , D M , Hankinson , S E , Hough , H , Spiegelman , D Colditz , G A . 1999 . N-acetyl transferase 2 genotypes, meat intake and breast cancer risk . Int J Cancer , 80 : 13 – 17 .
  • Ambrosone , C B , Freudenheim , J L , Sinha , R , Graham , S Marshall , J R . 1998 . Breast cancer risk, meat consumption and N-acetyltransferase (NAT2) genetic polymorphisms . Int J Cancer , 75 : 825 – 830 .
  • Delfino , R J , Sinha , R , Smith , C , West , J White , E . 2000 . Breast cancer, heterocyclic aromatic amines from meat and N-acetyltransferase 2 genotype . Carcinogenesis , 21 : 607 – 615 .
  • Ochs-Balcom , H M , Wiesner , G and Elston , R C . 2007 . A meta-analysis of the association of N-acetyltransferase 2 gene (NAT2) variants with breast cancer . Am J Epidemiol , 166 : 246 – 254 .
  • Egan , K M , Newcomb , P A , Titus-Ernstoff , L , Trentham-Dietz , A Mignone , L I . 2003 . Association of NAT2 and smoking in relation to breast cancer incidence in a population-based case-control study . Cancer Causes Control , 14 : 43 – 51 .
  • Ambrosone , C B , Kropp , S , Yang , J , Yao , S Shields , P G . 2008 . Cigarette smoking, N-acetyltransferase 2 genotypes, and breast cancer risk: pooled analysis and meta-analysis . Cancer Epidemiol Biomarkers Prev , 17 : 15 – 26 .
  • Salvini , S , Hunter , D J , Sampson , L , Stampfer , M J Colditz , G A . 1989 . Food-based validation of a dietary questionnaire: the effects of week-to-week variation in food consumption . Int J Epidemiol , 18 : 858 – 867 .
  • Voskuil , D W , Augustsson , K , Dickman , P W , van't Veer , P and Steineck , G . 1999 . Assessing the human intake of heterocyclic amines: limited loss of information using reduced sets of questions . Cancer Epidemiol Biomarkers Prev , 8 : 809 – 814 .
  • Sinha , R . 2002 . An epidemiologic approach to studying heterocyclic amines . Mutat Res , 506–507 : 197 – 204 .
  • National Cancer Institute . 2004 . Computerized Heterocyclic Amines Resource for Research in Epidemiology of Disease (CHARRED). Version 1.6 Bethesda, MD
  • Sinha , R , Rothman , N , Salmon , C P , Knize , M G Brown , E D . 1998 . Heterocyclic amine content in beef cooked by different methods to varying degrees of doneness and gravy made from meat drippings . Food Chem Toxicol , 36 : 279 – 287 .
  • Sinha , R , Rothman , N , Brown , E D , Salmon , C P Knize , M G . 1995 . High concentrations of the carcinogen 2-amino-1-methyl-6-phenylimidazo- [4,5-b]pyridine (PhIP) occur in chicken but are dependent on the cooking method . Cancer Res , 55 : 4516 – 4519 .
  • Vatsis , K P , Weber , W W , Bell , D A , Dupret , J M Evans , D A . 1995 . Nomenclature for N-acetyltransferases . Pharmacogenetics , 5 : 1 – 17 .
  • Titus-Ernstoff , L , Egan , K , Newcomb , P , Baron , J Stampfer , M . 1998 . Exposure to breast milk in infancy and breast cancer risk in post-menopausal women . J Natl Cancer Inst , 90 : 921 – 924 .
  • Sinha , R and Rothman , N . 1999 . Role of well-done, grilled red meat, heterocyclic amines (HCAs) in the etiology of human cancer . Cancer Lett , 143 : 189 – 194 .
  • Lang , N P , Butler , M A , Massengill , J , Lawson , M Stotts , R C . 1994 . Rapid metabolic phenotypes for acetyltransferase and cytochrome P4501A2 and putative exposure to food-borne heterocyclic amines increase the risk for colorectal cancer or polyps . Cancer Epidemiol Biomarkers Prev , 3 : 675 – 682 .
  • Zhu , J , Chang , P , Bondy , M L , Sahin , A A Singletary , S E . 2003 . Detection of 2-amino-1-methyl-6-phenylimidazo[4,5-b]-pyridine-DNA adducts in normal breast tissues and risk of breast cancer . Cancer Epidemiol Biomarkers Prev , 12 : 830 – 837 .
  • Pfeifer , G P , Denissenko , M F , Olivier , M , Tretyakova , N Hecht , S S . 2002 . Tobacco smoke carcinogens, DNA damage and p53 mutations in smoking-associated cancers . Oncogene , 21 : 7435 – 7451 .
  • Furihata , C and Matsushima , T . 1986 . Mutagens and carcinogens in foods . Annu Rev Nutr , 6 : 67 – 94 .
  • Murray , S , Lake , B G , Gray , S , Edwards , A J Springall , C . 2001 . Effect of cruciferous vegetable consumption on heterocyclic aromatic amine metabolism in man . Carcinogenesis , 22 : 1413 – 1420 .
  • Bogaards , J J , Verhagen , H , Willems , M I , van Poppel , G and van Bladeren , P J . 1994 . Consumption of Brussels sprouts results in elevated alpha-class glutathione S-transferase levels in human blood plasma . Carcinogenesis , 15 : 1073 – 1075 .
  • Pantuck , E J , Pantuck , C B , Garland , W A , Min , B H Wattenberg , L W . 1979 . Stimulatory effect of Brussels sprouts and cabbage on human drug metabolism . Clin Pharmacol Ther , 25 : 88 – 95 .
  • Pantuck , E J , Pantuck , C B , Anderson , K E , Wattenberg , L W Conney , A H . 1984 . Effect of brussels sprouts and cabbage on drug conjugation . Clin Pharmacol Ther , 35 : 161 – 169 .
  • Garte , S , Gaspari , L , Alexandrie , A K , Ambrosone , C Autrup , H . 2001 . Metabolic gene polymorphism frequencies in control populations . Cancer Epidemiol Biomarkers Prev , 10 : 1239 – 1248 .
  • Wacholder , S , Rothman , N and Caporaso , N . 2000 . Population stratification in epidemiologic studies of common genetic variants and cancer: quantification of bias . J Natl Cancer Inst , 92 : 1151 – 1158 .
  • Salmon , C P , Knize , M G and Felton , J S . 1997 . Effects of marinating on heterocyclic amine carcinogen formation in grilled chicken . Food Chem Toxicol , 35 : 433 – 441 .
  • Byrne , C , Sinha , R , Platz , E A , Giovannucci , E Colditz , G A . 1998 . Predictors of dietary heterocyclic amine intake in three prospective cohorts . Cancer Epidemiol Biomarkers Prev , 7 : 523 – 529 .
  • Cantwell , M , Mittl , B , Curtin , J , Carroll , R Potischman , N . 2004 . Relative validity of a food frequency questionnaire with a meat-cooking and heterocyclic amine module . Cancer Epidemiol Biomarkers Prev , 13 : 293 – 298 .

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