Probiotics Regulate the Expression of COX-2 in Intestinal Epithelial Cells

REFERENCES

• Eaden , J A , Abrams , K R and Mayberry , J F . 2001 . The risk of colorectal cancer in ulcerative colitis: a meta-analysis . Gut , 48 : 526 – 535 .
   PubMed Web of Science ®Google Scholar
• Munkholm , P . 2003 . Review article: the incidence and prevalence of colorectal cancer in inflammatory bowel disease . Aliment Pharmacol Ther , 18 ( 2 Suppl ) : 1 – 5 .
   PubMed Web of Science ®Google Scholar
• Weitzman , S A and Gordon , L I . 1990 . Inflammation and cancer: role of phagocyte-generated oxidants in carcinogenesis . Blood , 76 : 655 – 663 .
   PubMed Web of Science ®Google Scholar
• Gupta , R A and DuBois , R N . 2001 . Colorectal cancer prevention and treatment by inhibition of cyclooxygenase-2 . Nat Rev Cancer , 1 : 11 – 21 .
   PubMed Web of Science ®Google Scholar
• Kawai , N , Tsujii , M and Tsuji , S . 2002 . Cyclooxygenases and colon cancer . Prostaglandins Other Lipid Mediat , 187 : 19668 – 19669 .
   Google Scholar
• Ristimaki , A , Honkanen , N , Jankala , H , Sipponen , P and Harkonen , M . 1997 . Expression of cyclooxygenase-2 in human gastric carcinoma . Cancer Res , 57 : 1276 – 1280 .
   PubMed Web of Science ®Google Scholar
• Brown , J R and DuBois , R N . 2004 . Cyclooxygenase as a target in lung cancer . Clin Cancer Res , 10 : 4266s – 4269s . (12 Pt 2)
   PubMed Web of Science ®Google Scholar
• Liu , C H , Chang , S H , Narko , K , Trifan , O C Wu , M T . 2001 . Overexpression of cyclooxygenase-2 is sufficient to induce tumorigenesis in transgenic mice . J Biol Chem , 276 : 18563 – 18569 .
   PubMed Web of Science ®Google Scholar
• Marnett , L J and DuBois , R N . 2002 . COX-2: a target for colon cancer prevention . Annu Rev Pharmacol Toxicol , 42 : 55 – 80 .
   PubMed Web of Science ®Google Scholar
• Thun , M J , Namboodiri , M M and Heath , C W Jr . 1991 . Aspirin use and reduced risk of fatal colon cancer . N Engl J Med , 325 : 1593 – 1596 .
   PubMed Web of Science ®Google Scholar
• Reddy , B S , Tokumo , K , Kulkarni , N , Aligia , C and Kelloff , G . 1992 . Inhibition of colon carcinogenesis by prostaglandin synthesis inhibitors and related compounds . Carcinogenesis , 13 : 1019 – 1023 .
   PubMed Web of Science ®Google Scholar
• Jacoby , R F , Marshall , D J , Newton , M A , Novakovic , K Tutsch , K . 1996 . Chemoprevention of spontaneous intestinal adenomas in the Apc Min mouse model by the nonsteroidal anti-inflammatory drug piroxicam . Cancer Res , 56 : 710 – 714 .
   PubMed Web of Science ®Google Scholar
• Ramsay , R G , Ciznadija , D , Vanevski , M and Mantamadiotis , T . 2003 . Transcriptional regulation of cyclooxygenase expression: three pillars of control . Int J Immunopathol Pharmacol , 16 : 59 – 67 .
   PubMed Web of Science ®Google Scholar
• Mitchell , J A , Akarasereenont , P , Thiemermann , C , Flower , R J and Vane , J R . 1993 . Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase . Proc Natl Acad Sci USA , 90 : 11693 – 11697 .
   PubMed Web of Science ®Google Scholar
• Vane , J R , Mitchell , J A , Appleton , I , Tomlinson , A Bishop-Bailey , D . 1994 . Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation . Proc Natl Acad Sci USA , 91 : 2046 – 2450 .
   PubMed Web of Science ®Google Scholar
• Guo , Y S , Hellmich , M R , Wen , X D and Townsend , C M Jr . 2001 . Activator protein-1 transcription factor mediates bombesin-stimulated cyclooxygenase-2 expression in intestinal epithelial cells . J Biol Chem , 276 : 22941 – 22947 .
   PubMed Web of Science ®Google Scholar
• Tessner , T G , Muhale , F , Schloemann , S , Cohn , S M Morrison , A . 2002 . Basic fibroblast growth factor up-regulates cyclooxygenase-2 in 1407 cells through p38 MAP kinase . Am J Physiol , 284 : G269 – G279 .
   Google Scholar
• Wollowski , I , Rechkemmer , G and Pool-Zobel , B L . 2001 . Protective role of probiotics and prebiotics in colon cancer . Am J Clin Nutr , 73 : 451 – 455 .
   PubMed Web of Science ®Google Scholar
• Reddy , B S and Riverson , A . 1993 . Inhibitory effect of Bifidobacterium longum on colon, mammary and liver carcinogenesis induced by 2-amino-3-methylimidazo[4,5-f]quinoline, a food mutagen . Cancer Res , 53 : 3914 – 3918 .
   PubMed Web of Science ®Google Scholar
• Goldin , B R and Gorbach , S L . 1980 . Effect of Lactobacillus acidophilus dietary supplements on 1,2-dimethylhydrazine dihydrochloride-induced intestinal cancer in rats . J Natl Cancer Inst , 64 : 263 – 265 .
   PubMed Web of Science ®Google Scholar
• Mitchell , J A , Larkin , S and Williams , T J . 1995 . Cyclooxygenase-2: regulation and relevance in inflammation . Biochem Pharmacol , 50 : 1535 – 1542 .
   PubMed Web of Science ®Google Scholar
• Wallace , J L . 2001 . Prostaglandin biology in inflammatory bowel disease . Gastroenterol Clin North Am , 30 : 971 – 980 .
   PubMed Web of Science ®Google Scholar
• Tanabe , T and Tohnai , N . 2002 . COX isozymes and their gene structures and expression . Prostaglandins Other Lipid Mediat , 68–69 : 95 – 114 .
   PubMed Web of Science ®Google Scholar
• Hinz , B and Brune , K . 2002 . Cyclooxygenase-2—10 years later . J Pharmacol Exp Ther , 300 : 367 – 375 .
   PubMed Web of Science ®Google Scholar
• Jobin , C , Morteau , O , Han , D S and Balfour Sartor , R . 1998 . Specific NF-kappaB blockade selectively inhibits tumor necrosis factor-alpha-induced COX-2 but not constitutive COX-1 gene expression in HT-29 cells . Immunology , 95 : 537 – 543 .
   PubMed Web of Science ®Google Scholar
• Weaver , S A , Russo , M P , Wright , K L , Kolios , G Jobin , C . 2001 . Regulatory role of phosphatidylinositol 3-kinase on TNF-alpha-induced cyclooxygenase 2 expression in colonic epithelial cells . Gastroenterology , 120 : 1117 – 1127 .
   PubMed Web of Science ®Google Scholar
• Guo , Y S , Cheng , J Z , Jin , G F , Gutkind , J S Hellmich , M R . 2002 . Gastrin stimulates cyclooxygenase-2 expression in intestinal epithelial cells through multiple signaling pathways: evidence for involvement of ERK5 kinase and transactivation of the epidermal growth factor receptor . J Biol Chem , 277 : 48755 – 48763 .
   PubMed Web of Science ®Google Scholar
• Colucci , R , Blandizzi , C , Tanini , M , Vassalle , C Breschi , M C . 2005 . Gastrin promotes human colon cancer cell growth via CCK-2 receptor-mediated cyclooxygenase-2 induction and prostaglandin E2 production . Br J Pharmacol , 144 : 338 – 348 .
   PubMed Web of Science ®Google Scholar
• Lammers , K M , Helwig , U , Swennen , E , Rizzello , F Venturi , A . 2002 . Effect of probiotic strains on interleukin 8 production by HT29/19A cells . Am J Gastroenterol , 97 : 1182 – 1186 .
   PubMed Web of Science ®Google Scholar
• Otte , J M and Podolsky , D K . 2004 . Functional modulation of enterocytes by gram-positive and gram-negative microorganisms . Am J Physiol Gastrointest Liver Physiol , 286 : G613 – G626 .
   PubMed Web of Science ®Google Scholar
• Komori , M , Tsuji , S , Sun , W H , Tsujii , M Kawai , N . 2002 . Gastrin enhances gastric mucosal integrity through cyclooxygenase-2 upregulation in rats . Am J Physiol Gastrointest Liver Physiol , 283 : G1368 – G1378 .
   PubMed Web of Science ®Google Scholar
• Tsuji , S , Sun , W H , Tsujii , M , Kawai , N Kimura , A . 2002 . Lansoprazole induces mucosal protection through gastrin receptor-dependent up-regulation of cyclooxygenase-2 in rats . J Pharmacol Exp Ther , 303 : 1301 – 1308 .
   PubMed Web of Science ®Google Scholar
• Yao , M , Song , D H , Rana , B and Wolfe , M M . 2002 . COX-2 selective inhibition reverses the trophic properties of gastrin in colorectal cancer . Br J Cancer , 87 : 574 – 579 .
   PubMed Web of Science ®Google Scholar
• Whittle , B J . 2003 . Gastrointestinal effects of nonsteroidal anti-inflammatory drugs . Fundam Clin Pharmacol , 17 : 301 – 313 .
   PubMed Web of Science ®Google Scholar
• Kruis , W , Fric , P , Pokrotnieks , J , Lukas , M Fixa , B . 2004 . Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as with standard mesalazine . Gut , 53 : 1617 – 1623 .
   PubMed Web of Science ®Google Scholar
• Matsumoto , S , Hara , T , Hori , T , Mitsuyama , K Nagaoka , M . 2005 . Probiotic Lactobacillus-induced improvement in murine chronic inflammatory bowel disease is associated with the down-regulation of pro-inflammatory cytokines in lamina propria mononuclear cells . Clin Exp Immunol , 140 : 417 – 426 .
   PubMed Web of Science ®Google Scholar
• Yan , F , Cao , H , Cover , T L , Whitehead , R Washington , M K . 2007 . Soluble proteins produced by probiotic bacteria regulate intestinal epithelial cell survival and growth . Gastroenterology , 132 : 562 – 575 .
   PubMed Web of Science ®Google Scholar
• Chapman , T M , Plosker , G L and Figgitt , D P . 2007 . Spotlight on VSL#3 probiotic mixture in chronic inflammatory bowel diseases . BioDrugs , 21 : 61 – 63 .
   PubMed Web of Science ®Google Scholar
• Nurmi , J T , Puolakkainen , P A and Rautonen , N E . 2005 . Bifidobacterium Lactis sp. 420 up-regulates cyclooxygenase (Cox)-1 and down-regulates Cox-2 gene expression in a Caco-2 cell culture model . Nutr Cancer , 51 : 83 – 92 .
   PubMed Web of Science ®Google Scholar
• Brzozowski , T , Konturek , P C , Mierzwa , M , Drozdowicz , D Bielanski , W . 2006 . Effect of probiotics and triple eradication therapy on the cyclooxygenase (COX)-2 expression, apoptosis, and functional gastric mucosal impairment in Helicobacter pylori-infected Mongolian gerbils . Helicobacter , 11 : 10 – 20 .
   PubMed Web of Science ®Google Scholar
• Peran , L , Camuesco , D , Comalada , M , Bailon , E Henriksson , A . 2007 . A comparative study of the preventative effects exerted by three probiotics, Bifidobacterium lactis, Lactobacillus casei Lactobacillus acidophilus, in the TNBS model of rat colitis . J Appl Microbiol , 103 : 836 – 844 .
   PubMed Web of Science ®Google Scholar
• Rachmilewitz , D , Katakura , K , Karmeli , F , Hayashi , T Reinus , C . 2004 . Toll-like receptor 9 signaling mediates the anti-inflammatory effects of probiotics in murine experimental colitis . Gastroenterology , 126 : 520 – 528 .
   PubMed Web of Science ®Google Scholar
• Obermeier , F , Strauch , U G , Dunger , N , Grunwald , N Rath , H C . 2005 . In vivo CpG DNA/toll-like receptor 9 interaction induces regulatory properties in CD4+CD62L+ T cells which prevent intestinal inflammation in the SCID transfer model of colitis . Gut , 54 : 1428 – 1436 .
   PubMed Web of Science ®Google Scholar
• Cario , E , Gerken , G and Podolsky , D K . 2007 . Toll-like receptor 2 controls mucosal inflammation by regulating epithelial barrier function . Gastroenterology , 132 : 1359 – 1374 .
   PubMed Web of Science ®Google Scholar
• Fukata , M , Chen , A , Klepper , A , Krishnareddy , S Vamadevan , A S . 2006 . Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: role in proliferation and apoptosis in the intestine . Gastroenterology , 131 : 862 – 877 .
   PubMed Web of Science ®Google Scholar
• Yeo , S J , Gravis , D , Yoon , J G and Yi , A K . 2003 . Myeloid differentiation factor 88-dependent transcriptional regulation of cyclooxygenase-2 expression by CpG DNA: role of NF-kappaB and p38 . J Biol Chem , 278 : 22563 – 22573 .
   PubMed Web of Science ®Google Scholar
• Suzuki , M , Hisamatsu , T and Podolsky , D K . 2003 . Gamma interferon augments the intracellular pathway for lipopolysaccharide (LPS) recognition in human intestinal epithelial cells through coordinated up-regulation of LPS uptake and expression of the intracellular Toll-like receptor 4-MD-2 complex . Infect Immun , 71 : 3503 – 3511 .
   PubMed Web of Science ®Google Scholar