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Original Articles

Soy Isoflavones Ameliorate the Adverse Effects of Chemotherapy in Children

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Pages 1001-1005 | Received 23 May 2010, Accepted 16 Jul 2010, Published online: 04 Oct 2010

REFERENCES

  • Sarkar , F H and Li , Y . 2004 . The role of isoflavones in cancer chemoprevention . Front Biosci , 9 : 2714 – 2724 .
  • Zhou , J R , Gugger , E T , Tanaka , T , Guo , Y Blackburn , G L . 1999 . Soybean phytochemicals inhibit the growth of transplantable human prostate carcinoma and tumor angiogenesis in mice . J Nutr , 129 : 1628 – 1635 .
  • Hussain , M , Banerjee , M , Sarkar , F H , Djuric , Z Pollak , M N . 2003 . Soy isoflavones in the treatment of prostate cancer . Nutr Cancer , 47 : 111 – 117 .
  • Li , Y , Kucuk , O , Hussain , M , Abrams , J Cher , M L . 2006 . Antitumor and antimetastatic activities of docetaxel are enhanced by genistein through regulation of osteoprotegerin/receptor activator of nuclear factor-kappaB (RANK)/receptor activator of nuclear factor kappaB ligand (RANKL)/matrix metalloproteinase-9 (MMP-9) signaling in prostate cancer . Cancer Res , 66 : 4816 – 4825 .
  • Li , Y , Ahmed , F , Ali , S , Philip , P A Kucuk , O . 2005 . Inactivation of nuclear factor-kappaB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells . Cancer Res , 65 : 6934 – 6942 .
  • Mohammad , R M , Banerjee , S , Li , Y , Aboukameel , A Kucuk , O . 2006 . Anti-tumor activity of cisplatin is potentiated by soy isoflavone genistein in BxPC-3 pancreatic tumor xenografts . Cancer , 1006 : 1260 – 1268 .
  • Khoshyomn , S , Manske , G C , Lew , S M , Wald , S L and Penar , P L . 2000 . Synergistic action of genistein and cisplatin on growth inhibition and cytotoxicity of human medulloblastoma cells . Pediatr Neurosurg , 33 : 123 – 131 .
  • Hillman , G G , Forman , J D , Kucuk , O , Yudelev , M Maughan , R L . 2001 . Genistein potentiates radiation effect on prostate carcinoma cells . Clin Cancer Res , 7 : 382 – 390 .
  • Hillman , G G , Wang , Y , Kucuk , O , Che , M Doerge , D R . 2004 . Genistein potentiates inhibition of tumor growth by radiation in a prostate cancer orthotopic model . Mol Cancer Ther , 3 : 1271 – 1279 .
  • Raffoul , J J , Banerjee , S , Che , M , Knoll , Z E Doerge , D R . 2007 . Soy isoflavones enhance radiotherapy in a metastatic prostate cancer model . Int J Cancer , 120 : 2491 – 2498 .
  • Yashar , C M , Spanos , W J , Taylor , D D and Gercel-Taylor , C . 2005 . Potentiation of the radiation effect with genistein in cervical cancer cells . Gynecol Oncol , 99 : 199 – 205 .
  • Djuric , Z , Chen , G , Doerge , D , Heilbrun , L and Kucuk , O . 2001 . Effect of soy supplementation on oxidative stress in men and women . Cancer Lett , 172 : 1 – 6 .
  • Ruiz-Larrea , M B , Mohan , A R , Paganga , G , Miller , N J Bolwell , G P . 1997 . Antioxidant activity of phytoestrogenic isoflavones . Free Radic Res , 26 : 63 – 70 .
  • Kapiotis , S , Hermann , M , Held , I , Seelos , C Ehringer , H . 1997 . Genistein, the dietary-derived angiogenesis inhibitor, prevents LDL oxidation and protects endothelial cells from damage by atherogenic LDL . Arterioscler Thromb Vasc Biol , 17 : 2868 – 2874 .
  • Blay , M , Espinel , A E , Delgado , M A , Baiges , I Bladé , C . 2010 . Isoflavone effect on gene expression profile and biomarkers of inflammation . J Pharm Biomed Anal , 51 : 382 – 390 .
  • Hall , W L , Vafeiadou , K , Hallund , J , Bügel , S Koebnick , C . 2005 . Soy-isoflavone-enriched foods and inflammatory biomarkers of cardiovascular disease risk in postmenopausal women: interactions with genotype and equol production . Am J Clin Nutr , 82 : 1260 – 1268 .
  • Duan , W , Kuo , I C , Selvarajan , S , Chua , K Y Bay , B H . 2003 . Anti-inflammatory effects of genistein, a tyrosine kinase inhibitor, on a guinea pig model of asthma . Am J Respir Crit Care Med , 167 : 185 – 192 .
  • Park , Y J , Jang , Y M and Kwon , Y H . 2009 . Isoflavones prevent endoplasmic reticulum stress-mediated neuronal degeneration tau hyperphosphorylation in SH-SY5Y cells . J Med Food , 12 : 528 – 535 .
  • Kuzu , N , Metin , K , Dagli , A F , Akdemir , F Orhan , C . 2007 . Protective role of genistein in acute liver damage induced by carbon tetrachloride . Mediators Inflamm , doi: doi: 10.1155/2007/36381
  • Ahmad , I U , Forman , J D , Sarkar , F H , Hillman , G G Heath , E . Soy Isoflavones in conjunction with radiation therapy in patients with prostate cancer . Nutr Cancer. , Forthcoming
  • Piskula , M K , Yamakoshi , J and Iwai , Y . 1999 . Daidzein and genistein but not their glucosides are absorbed from the rat stomach . FEBS Lett , 447 : 287 – 291 .
  • Takimoto , C H , Glover , K , Huang , X , Hayes , S A Gallot , L . 2003 . Phase I pharmaco kinetic and pharmacodynamic analysis of unconjugated soy isoflavones administered to individuals with cancer . Cancer Epidemiol Biomarkers Prev , 12 : 1213 – 1221 .
  • Fischer , L , Mahoney , C , Jeffcoat , A R , Koch , M A Thomas , B E . 2004 . Clinical characteristics and pharmacokinetics of purified soy isoflavones: multiple-dose administration to men with prostate neoplasia . Nutr Cancer , 48 : 160 – 170 .
  • Kumar , N B , Krischer , J P , Allen , K , Riccardi , D Besterman-Dahan , K . 2007 . A phase II randomized, placebo-controlled clinical trial of purified isoflavones in modulating steroid hormones in men diagnosed with localized prostate cancer . Nutr Cancer , 59 : 163 – 168 .
  • Sakai , T and Kogiso , M . 2008 . Soy isoflavones and immunity . J Med Invest , 55 : 167 – 173 .
  • Andres , A , Donovan , S M and Kuhlenschmidt , M S . 2009 . Soy isoflavones and virus infections . J Nutr Biochem , 20 : 563 – 569 .

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