93
Views
10
CrossRef citations to date
0
Altmetric
Original Articles

Preventive Activity of Olive Oil Phenolic Compounds on Alkene Epoxides Induced Oxidative DNA Damage on Human Peripheral Blood Mononuclear Cells

, , , , &
Pages 1322-1330 | Received 16 May 2014, Accepted 12 Aug 2014, Published online: 09 Oct 2014

REFERENCES

  • Rumchev K, Brown H, and Spickett, J: Volatile organic compounds: do they present a risk to our health? Rev Environ Health 22, 39–55, 2007.
  • Hurst HE: Toxicology of 1,3-butadiene, chloroprene, and isoprene. Rev Environ Contam Toxicol 189, 131–179, 2007.
  • Fabiani R, Rosignoli P, De Bartolomeo A, Fuccelli R, and Morozzi G: Genotoxicity of alkene epoxide in human peripheral blood mononuclear cells and HL60 leukemia cells evaluated with the comet assay. Mutat Res 747, 1–6, 2012.
  • Albertini RJ, Carson ML, Kirman CR, and Gargas ML: 1,3-Butadiene: II. Genotoxicity profile. Crit Rev Toxicol 40, 12–73, 2010.
  • Cemeli E, Mirkova E, Chiuchiarelli G, Alexandrova E, and Anderson D: Investigation on the mechanisms of genotoxicity of butadiene, styrene and their combination in human lymphocytes using the comet assay. Mut Res 664, 69–76, 2009.
  • Vodicka P, Koskinen M, Naccarati A, Oesch-Bartlomowicz B, Vodickova L, et al.: Styrene metabolism, genotoxicity, and potential carcinogenicity. Drug Metab Rev 38, 805–853, 2006.
  • Dhawan A, Bajpayee M, and Parmar D: Comet assay: a reliable tool for the assessment of DNA damage in different models. Cell Biol Toxicol 25, 5–32, 2009.
  • Collins AR: Investigating oxidative DNA damage and its repair using the comet assay. Mut Res 681, 24–32, 2009.
  • Bastlová T, Vodicka P, Peterková K, Hemminki K, and Lambert B: Styrene oxide-induced HPRT mutations, DNA adducts and DNA strand breaks in cultured human lymphocytes. Carcinogenesis 16, 2357–2362, 1995.
  • Laffon B, Pásaro E, and Méndez J: Genotoxic effects of styrene-7,8-oxide in human white blood cells: comet assay in relation to the induction of sister-chromatid exchanges and micronuclei. Mut Res 491, 163–172, 2001.
  • Laffon B, Pásaro E, and Méndez J: DNA damage and repair in human leucocytes exposed to styrene-7,8-oxide measured by the comet assay. Tox Letters 126, 61–68, 2002.
  • Laffon B, Pérez-Cadahía B, Pásaro E, and Méndez J: Effect of epoxide hydrolase and glutathione S-transferase genotypes on the induction of micronuclei and DNA damage by styrene-7,8-oxide in vitro. Mut Res 536, 49–59, 2003.
  • Laffon B, Pérez-Cadahía B, Pásaro E, and Méndez J: Individual sensitivity to DNA damage induced by styrene in vitro: influence of cytochrome p450, epoxide hydrolase and glutathione S-transferase genotypes. Toxicology 186, 131–141, 2003.
  • Buschini A, De Palma G, Poli P, Martino A, Rossi C, et al.: Genetic polymorphism of drug-metabolizing enzymes and styrene-induced DNA damage. Environ Mol Mutagen 41, 243–252, 2003.
  • Köhlerová R and Stĕtina R: The repair of DNA damage induced in human peripheral lymphocytes with styrene oxide. Acta Medica (Hradec Kralove) 46, 95–100, 2003.
  • Godderis L, De Boeck M, Haufroid V, Emmery M, Mateuca R, et al.: Influence of genetic polymorphisms on biomarkers of exposure and genotoxic effects in styrene-exposed workers. Environ Mol Mutagen 44, 293–303, 2004.
  • Godderis L, Aka P, Mateuca R, Kirsch-Volders M, Lison D, et al.: Dose-dependent influence of genetic polymorphisms on DNA damage induced by styrene oxide, ethylene oxide and gamma-radiation. Toxicology 219, 220–229, 2006.
  • Anderson D, Dobrzynska MM, and Basaran N: Effects of various genotoxins and reproductive toxins in human lymphocytes and sperm in the comet assay. Terat Carcin Mut 17, 29–43, 1997.
  • Kligerman AD and Hu Y: Some insights into the mode of action of butadiene by examining the genotoxicity of its metabolites. Chem Biol Interact 166, 132–139, 2007.
  • Zhang PP, Wen Y, An J, Yu YX, Wu MH, and Zhang XY: DNA damage induced by three major metabolites of 1,3-butadiene in human hepatocyte L02 cells. Mutat Res 747, 240– 245, 2012.
  • Servili M and Montedoro GF: Contribution of phenolic compounds to virgin olive oil quality. Eur J Lipid Sci Technol 104, 602–613, 2002.
  • Servili M, Esposto S, Fabiani R, Urbani S, Taticchi A, et al.: Phenolic compounds in olive oil: antioxidant, health and organoleptic activities according to their chemical structure. Inflammopharmacology 17, 76–84, 2009.
  • De Flora S, Izzotti A, D’agostini F, Balansky RM, Noonan D, et al.: Multiple points of intervention of cancer and other mutation–related diseases. Mutat Res 480/481, 9–22, 2001.
  • Deiana M, Aruoma OI, Bianchi MP, Spencer JPE, Kaur H, et al.: Inhibition of peroxunitrite dependent DNA base modification and tyrosine nitration by the extra virgin olive oil derived antioxidant hydroxytyrosol. Free Radic Biol Med 26, 762–769, 1999.
  • Quiles JL, Farquharson AJ, Simpson DK, Grant I, and Wahle KWJ: Olive oil phenolics: effects on DNA oxidation and redox enzyme mRNA in prostate cells. Br J Nutr 28, 225–234, 2002.
  • Nousis L, Doulias PT, Aligiannis N, Bazios D, Agalias A, et al.: DNA protecting and genotoxic effects of olive oil related components in cells exposed to hydrogen peroxide. Free Radic Res 39, 787–795, 2005.
  • Grasso S, Siracusa L, Spatafora C, Renis M, and Tringali C: Hydroxytyrosol lipophilic analogues: enzymatic synthesis, radical scavenging activity and DNA oxidative damage protection. Bioorg Chem 35, 137–152, 2007.
  • Young J, Wahle KWJ, and Boyle SP: Cytoprotective effects of phenolic antioxidants and essential fatty acids in human blood monocyte and neuroblastoma cell lines: Surrogates for neurological damage in vivo. Prostaglandins, Leukotr Essent Fatty Acids 78, 45–59, 2008.
  • Fabiani R, Rosignoli P, De Bartolomeo A, Fuccelli R, Servili M, et al.: Oxidative DNA damage is prevented by extracts of olive oil, hydroxytyrosol, and other olive phenolic compounds in human blood mononuclear cells and HL60 cells. J Nutr 138, 1411–1416, 2008.
  • Warleta F, Sánchez Quesada C, Campos M, Allouche Y, Beltrán G, et al.: Hydroxytyrosol protects against oxidative DNA damage in human breast cells. Nutrients 3, 839–857, 2011.
  • Li J, Yang G, Wang S, Jiang L, Liu X, et al.: The protective effects of hydroxytyrosol against orthophenylphenol-induced DNA damage in HepG2 cells. Toxicol Mech Methods 22, 432–437, 2012.
  • Zhang Y, Jiang L, Jiang L, Geng C, Li L, et al.: Possible involvement of oxidative stress in potassium bromate-induced genotoxicity in human HepG2 cells. Chem Biol Interact 189, 186–191, 2011.
  • Zhang X, Cao J, Jiang L, Geng C, and Zhong L: Protective effect of hydroxytyrosol against acrylamide-induced cytotoxicity and DNA damage in HepG2 cells. Mutat Res 664, 64–68, 2009.
  • Zhang X, Jiang L, Geng C, Cao J, and Zhong L: The role of oxidative stress in deoxynivalenol-induced DNA damage in HepG2 cells. Toxicol 54, 513–518, 2009.
  • Zhang X, Jiang L, Geng C, Hu C, Yoshimura H, et al.: Inhibition of Sudan I genotoxicity in human liver-derived HepG2 cells by the antioxidant hydroxytyrosol. Free Radic Res 42, 189–195, 2008.
  • Ilavarasi K, Kiruthiga PV, Pandian SK, and Devi KP: Hydroxytyrosol, the phenolic compound of olive oil protect human PBMC against oxidative stress and DNA damage mediated by 2,3,7,8-TCDD. Chemosphere 84, 888–893, 2011.
  • Guo W, An Y, Jiang L, Geng C, and Zhong L: The protective effects of hydroxytyrosol against UVB-induced DANN damage in HaCaT cells. Phytother Res 24, 352–359, 2010.
  • Liu Z, Sun L, Zhu L, Jia X, Li X, et al.: Hydroxytyrosol protects retinal pigment epithelial cells from acrolein-induced oxidative stress and mitochondrial dysfunction. J Neurochem 103, 2690–2700, 2007.
  • Erol Ö, Arda N, and Erdem G: Phenols of virgin olive oil protects nuclear DNA against oxidative damage in HeLa cells. Food Chem Toxicol 50, 3475–3479, 2012.
  • Rosignoli P, Fabiani R, De Bartolomeo A, Fuccelli R, Pelli MA, et al.: Genotoxic effect of bile acids on human normal and tumor cells and protection by dietary antioxidants and butyrate. Eur J Nutr 47, 301–309, 2008.
  • Collins AR, Duthie SJ, and Dobson VL: Direct enzyme detection of endogenous oxidative base damage in human lymphocytes DNA. Carcinogenesis 14, 1733–1735, 1993.
  • Koskinen M and Plnà K: Specific DNA adducts by some mono-substituted epoxides in vitro and in vivo. Chem Biol Interact 129, 209–229, 2000.
  • Speit G and Hartaman A: The comet assay: a sensitive genotoxicity test for the detection of DNA damage and repair. Methods Mol Biol 314, 275–286, 2006.
  • Fortini P, Raspaglio G, Falchi M, and Dogliotti E: Analysis of DNA alkylation damage and repair in mammalian cells by the comet assay. Mutagenesis 11, 169–175, 1996.
  • Vettori MV, Caglieri A, Goldoni M, Castaldi AF, Darè E, et al.: Analysis of oxidarive stress in SK-N-MC neurons exposed to styrene-7,8-oxide. Toxicol in Vitro 19, 11–20, 2005.
  • Meszka-Jordan A, Mahlapuu R, Soomets U, and Carlson GP: Oxidative stress due to (R)-styrene oxide exposure and the role of antioxidants in non-Swiss albino mice. J Toxicol Environ Health A 72, 642–650, 2009.
  • Harvilchuck JA, Pu X, Klaunig JE, and Carlson GP: Indicators of oxidative stress and apoptosis in mouse whole lung and Clara cells following exposure to styrene and its metabolites. Toxicology 264, 171–178, 2009.
  • Yadavilli S, Martinez-Ceballos E, Snowden-Aikens J, Hurst A, Joseph T, et al.: Diepoxybutane activates the mitochondrial apoptotic pathway and mediates apoptosis in human lymphoblasts through oxidative stress. Toxicol in Vitro 21, 1429–1441, 2007.
  • De Flora S, Izzotti A, D’agostini F, and Balansky RM: Mechanisms of N-acetylcysteine in the prevention of DNA damage and cancer, with special references to smoking-related end-points. Carcinogenesis 22, 999–1013, 2001.
  • Harvilchuck JA and Carlson GP: Comparison of styrene and its metabolites styrene oxide and 4-vinylphenol on cytotoxicity and glutathione depletion in Clara cells of mice and rats. Toxicology 227, 165–172, 2006.
  • Niture SK, Velu CS, Smith QR, Bhat GJ, and Srivenugopal KS: Increased expression of the MGMT repair protein mediated by cysteine prodrugs and chemopreventive natural products in human lymphocytes and tumor cell lines. Carcinogenesis 28, 378–389, 2007.
  • Pelucchi C, Bosetti C, Negri E, Lipworth L, and La Vecchia C: Olive oil and cancer risk: an update of epidemiological findings through 2010. Curr Pharm Des 17, 805–812, 2011.
  • Casaburi I, Puoci F, Chimento A, Sirianni R, Ruggiero C, et al.: Potential of olive oil phenols as chemopreventive and therapeutic agents against cancer: a review of in vitro studies. Mol Nutr Food Res 57, 71–83, 2013.
  • Raederstorf D: Antioxidant activity of olive oil polyphenols in human: a review. Int J Vitam Nutr Res 79, 152–165, 2009.
  • Mirò-Casas E, Covas MI, Fitò M, Farré-Albadalejo M, Marrugat J, et al.: Tyrosol and hydroxytyrosol are absorbed from moderate and sustained doses of virgin olive oil in humans. Eur J Clin Nutr 57, 186–190, 2003.
  • Covas MI, de la Torre K, Farré-Albadalejo M, Kaikkonen J, Fitò M, et al.: Postprandial LDL phenolic content and LDL oxidation are modulated by olive oil phenolic compounds in human. Free Radic Biol Med 40, 608–616, 2006.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.