References
- Delyon J, Maio M, and Lebbé C: The ipilimumab lesson in melanoma: Achieving long-term survival. Semin Oncol 42, 387–401, 2015. doi:10.1053/j.seminoncol.2015.02.005
- Danielli R, Patuzzo R, Di Giacomo AM, Gallino G, Maurichi A, Di Florio A, et al.: Intralesional administration of L19-IL2/L19-TNF in stage III or stage IVM1a melanoma patients: results of a phase II study. Cancer Immunol Immunother 1–11, 2015. doi:10.1007/s00262-015-1704-6
- Beauchamp GK, Keast RSJ, Morel D, Lin J, Pika J, Han Q, et al.: Phytochemistry: ibuprofen-like activity in extra-virgin olive oil. Nature 437, 45–46, 2005. doi:10.1038/437045a
- Parkinson L and Keast R: Oleocanthal, a phenolic derived from virgin olive oil: a review of the beneficial effects on inflammatory disease. Int J Mol Sci 15, 12323–12334, 2014. doi:10.3390/ijms150712323
- Carpi S, Fogli S, Giannetti A, Adinolfi B, Tombelli S, Da Pozzo E, et al.: Theranostic properties of a survivin-directed molecular beacon in human melanoma cells. PLoS ONE 9, e114588, 2014. doi:10.1371/journal.pone.0114588
- Su DM, Zhang Q, Wang X, He P, Zhu YJ, Zhao J, et al.: Two types of human malignant melanoma cell lines revealed by expression patterns of mitochondrial and survival-apoptosis genes: implications for malignant melanoma therapy. Mol Cancer Ther 8, 1292–1304, 2009. doi:10.1158/1535-7163.MCT-08-1030
- Halaban R, Zhang W, Bacchiocchi A, Cheng E, Parisi F, Ariyan S, et al.: PLX4032, a selective BRAF(V600E) kinase inhibitor, activates the ERK pathway and enhances cell migration and proliferation of BRAF melanoma cells. Pigment Cell Melanoma Res 23, 190–200, 2010. doi:10.1111/j.1755-148X.2010.00685.x
- Arozarena I, Sanchez-Laorden B, Packer L, Hidalgo-Carcedo C, Hayward R, Viros A, et al.: Oncogenic BRAF induces melanoma cell invasion by downregulating the cGMP-specific phosphodiesterase PDE5A. Cancer Cell 19, 45–57, 2011. doi:10.1016/j.ccr.2010.10.029
- Akl MR, Ayoub NM, Mohyeldin MM, Busnena BA, Foudah AI, Liu Y-Y, et al.: Olive phenolics as c-Met inhibitors: (−)-Oleocanthal attenuates cell proliferation, invasiveness, and tumor growth in breast cancer models. PLoS ONE 9, e97622, 2014. doi:10.1371/journal.pone.0097622
- LeGendre O, Breslin PAS, and Foster DA: (−)-Oleocanthal rapidly and selectively induces cancer cell death via lysosomal membrane permeabilization (LMP). Mol Cell Oncol 2(4), e1006077, 2015. doi:10.1080/23723556.2015.1006077
- Oltersdorf T, Elmore SW, Shoemaker AR, Armstrong RC, Augeri DJ, Belli BA, et al.: An inhibitor of Bcl-2 family proteins induces regression of solid tumours. Nature 435, 677–681, 2005. doi:10.1038/nature03579
- Serasinghe MN, Missert DJ, Asciolla JJ, Podgrabinska S, Wieder SY, Izadmehr S, et al.: Anti-apoptotic BCL-2 proteins govern cellular outcome following B-RAF(V600E) inhibition and can be targeted to reduce resistance. Oncogene 34, 857–867, 2015. doi:10.1038/onc.2014.21
- Scotece M, Gomez R, Conde J, Lopez V, Gomez-Reino JJ, Lago F, et al.: Oleocanthal inhibits proliferation and MIP-1α expression in human multiple myeloma cells. Curr Med Chem 20(19), 2467–2475, 2013.
- Haarberg HE and Smalley KSM: Resistance to Raf inhibition in cancer. Drug Discov Today Technol 11, 27–32, 2014. doi:10.1016/j.ddtec.2013.12.004
- Cao H-H, Cheng C-Y, Su T, Fu X-Q, Guo H, Li T, et al.: Quercetin inhibits HGF/c-Met signaling and HGF-stimulated melanoma cell migration and invasion. Mol Cancer 14, 1–12, 2015. doi:10.1186/s12943-015-0367-4
- Gao L, Feng Y, Bowers R, Becker-Hapak M, Gardner J, Council L, et al.: Ras-associated protein-1 regulates extracellular signal-regulated kinase activation and migration in melanoma cells: two processes important to melanoma tumorigenesis and metastasis. Cancer Res 66, 7880–7888, 2006. doi:10.1158/0008-5472.CAN-06-0254
- Ma PC, Tretiakova MS, Nallasura V, Jagadeeswaran R, Husain AN, and Salgia R: Downstream signalling and specific inhibition of c-MET/HGF pathway in small cell lung cancer: implications for tumour invasion. Br J Cancer 97, 368–77, 2007. doi:10.1038/sj.bjc.6603884
- Busnena BA, Foudah AI, Melancon T, and Sayed El KA: Olive secoiridoids and semisynthetic bioisostere analogues for the control of metastatic breast cancer. Bioorg Med Chem 21, 2117–2127, 2013. doi:10.1016/j.bmc.2012.12.050
- Carpi S, Fogli S, Romanini A, Pellegrino M, Adinolfi B, Podestà A, et al.: AM251 induces apoptosis and G2/M cell cycle arrest in A375 human melanoma cells. Anticancer Drugs 2015;Publish Ahead of Print:1. doi:10.1097/CAD.0000000000000246
- Grösch S, Maier TJ, Schiffmann S, and Geisslinger G: Cyclooxygenase-2 (COX-2)-independent anticarcinogenic effects of selective COX-2 inhibitors. J Natl Cancer Inst 98, 736–747, 2006. doi:10.1093/jnci/djj206