References
- Paulos CM, Kaiser A, Wrzesinski C, Hinrichs CS, Cassard L, et al.: Toll-like receptors in tumor immunotherapy. Clin Cancer Res 13, 5280–5289, 2007.
- Jouhi L, Renkonen S, Atula T, Mäkitie A, Haglund C, et al.: Different toll-like receptor expression patterns in progression toward cancer. Front Immunol 5, 638, 2014.
- Toussi DN and Massari P: immune adjuvant effect of molecularly-defined toll-like receptor ligands. Vaccines (Basel) 2, 323–353, 2014.
- Werner J, Decarlo CA, Escott N, Zehbe L, Ulanova M, et al.: Expression of integrins and toll-like receptors in cervical cancer: effect of infectious agents. Innate Immun 18, 55–69, 2012.
- Yu L, Wang L, Li M, Zhong J, Wang Z, et al.: Expression of toll-like receptor 4 is downregulated during progression of cervical neoplasia. Cancer Immunol Immunother 59, 1021–1028, 2010.
- Akira S and Takeda K: Toll-like receptor signalling. Nat Rev Immunol 4, 499–511, 2004.
- Rossol M, Heine H, Meusch U, Quandt D, Klein C, et al.: LPS-induced cytokine production in human monocytes and macrophages. Crit Rev Immunol 31, 379–446, 2011.
- Bai C, Yang X, Zou K, He H, Wang J, et al.: Anti-proliferative effect of RCE-4 from Reineckia carnea on human cervical cancer HeLa cells by inhibiting the PI3K/Akt/mTOR signaling pathway and NF-κB activation. Naunyn Schmiedebergs Arch Pharmacol 389, 573–584, 2016.
- Zhou YX, Xin HL, Rahman K, Wang SJ, Peng C, et al.: Portulaca oleracea L.: a review of phytochemistry and pharmacological effects. Biomed Res Int 925631, 2015.
- Jiao ZZ, Yue S, Sun HX, Jin TY, Wang HN, et al.: Indoline amide glucosides from portulaca oleracea: isolation, structure, and DPPH radical scavenging activity. J Nat Prod 25, 2588–2597, 2015.
- Rashed AN, Afifi FU, and Disi AM: Simple evaluation of the wound healing activity of a crude extract of Portulaca oleracea L. (growing in Jordan) in Mus musculus JVI-1. J Ethnopharmacol 88, 131–136, 2003.
- Chen T, Zhu L, Liu X, Li Y, Zhao C, et al.: Synthesis and antioxidant activity of phosphorylated polysaccharide from Portulaca oleracea L. with H3PW12O40 immobilized on polyamine functionalized polystyrene bead as catalyst. J Mol Catal A Chem 342, 74–82, 2011.
- Zhao R, Cai YP, and Chen ZB: Anti-uterine cervix cancer study of polysaccharide from portulace oleracea L. on aged tumor-bearing mice. Chinese J Gerontol 9, 4480–4482, 2013.
- Zhao R, Gao X, Cai Y, Shao X, Jia G, et al.: Antitumor activity of Portulaca oleracea L. polysaccharides against cervical carcinoma in vitro and in vivo. Carbohyd Polym 96, 376–383, 2013.
- Zhao Y, Wang C, Wu Z, Fang J, Zhu L, et al.: Synthesis and antitumor activity of novel aroylthiourea derivatives of podophyllotoxin. Invest New Drugs 30, 17–24, 2012.
- Wang W, Nag SA, and Zhang R: Targeting the NFκB signaling pathways for breast cancer prevention and therapy. Curr Med Chem 22, 264–289, 2015.
- Shathish K, Sakthivel KM, and Guruvayoorappan C: Protective Effect of Solanum muricatum on tumor metastasis by regulating inflammatory mediators and nuclear factor-kappa B subunits. J Environ Pathol Toxicol Oncol 34, 249–262, 2015.
- Figueiredo RT, Bittencourt VC, Lopes LC, Sassaki G, and Barreto-Bergter E: Toll-like receptors (TLR2 and TLR4) recognize polysaccharides of Pseudallescheria boydii cell wall. Carbohydr Res 356, 260–264, 2012.
- Lin KI, Kao YY, Kuo HK, Yang WB, Chou A, et al.: Reishi polysaccharides induce immunoglobulin production through the TLR4/TLR2-mediated induction of transcription factor Blimp-1. J Biol Chem 281, 24111–24123, 2006.
- Xu YY, Zhang YY, Ou YY, Lu XX, Pan LY, et al.: Houttuynia cordata Thunb. polysaccharides ameliorates lipopolysaccharide-induced acute lung injury in mice. J Ethnopharmacol 16, pii: S0378–8741(15)30032–5, 2015.
- Lei W, Browning JD Jr, Eichen PA, Lu CH, Mossine VV, et al.: Immuno-stimulatory activity of a polysaccharide-enriched fraction of Sutherlandia frutescens occurs by the toll-like receptor-4 signaling pathway. J Ethnopharmacol 172, 247–253, 2015.
- Hsu HY, Hua KF, Lin CC, Lin CH, Hsu J, et al.: Extract of Reishi polysaccharides induces cytokine expression via TLR4-modulated protein kinase signaling pathways. J Immunol 173, 5989–5999, 2004.
- Yin X, Chen L, Liu Y, Yang J, Ma C, et al.: Enhancement of the innate immune response of bladder epithelial cells by Astragalus polysaccharides through upregulation of TLR4 expression. Biochem Biophys Res Commun 397, 232–238, 2010.
- Zhao R, Zhang T, Zhao H, and Cai Y: Effects of Portulaca oleracea L. polysaccharides on phenotypic and functional maturation of murine bone marrow derived dendritic cells. Nutr Cancer 67, 987–993, 2015.
- O'Neill LA: When signaling pathways collide: positive and negative regulation of toll-like receptor signal transduction. Immunity 29, 12–20, 2008.
- Lin WW and Karin M: A cytokine-mediated link between innate immunity, inflammation, and cancer. J Clin Invest 117, 1175–1183, 2007.
- Chai EZ, Siveen KS, Shanmugam MK, Arfuso F, Sethi G, et al.: Analysis of the intricate relationship between chronic inflammation and cancer. Biochem J 468, 1–15, 2015.
- Balkwill F and Coussens LM: Cancer: an inflammatory link. Nature 431, 405–406, 2004.
- Chow MT and Luster AD: Chemokines in cancer. Cancer Immunol Res 2, 1125–1131, 2014.
- Vendramini-Costa DB and Carvalho JE: Molecular link mechanisms between inflammation and cancer. Curr Pharm Des 18, 3831–3852, 2012.
- Thompson PA, Khatami M, and Baglole CJ: Environmental immune disruptors, inflammation and cancer risk. Carcinogenesis 1, S232–S253, 2015.
- Miao JW, Liu LJ, and Huang J: Interleukin-6-induced epithelial-mesenchymal transition through signal transducer and activator of transcription 3 in human cervical carcinoma. Int J Oncol 45, 165–176, 2014.
- Hefler LA, Grimm C, and Ackermann S: An interleukin-6 gene promoter polymorphism influences the biological phenotype of ovarian cancer. Cancer Res 63, 3066–3068, 2003.
- Kassim SK, El-Salahy EM, Fayed ST, Helal SA, Helal T, et al.: Vascular endothelial growth factor and interleukin-8 are associated with poor prognosis in epithelial ovarian cancer patients. Clin Biochem 37, 363–369, 2004.
- Chen B, Hou ZH, Dong Z, and Li CD: Crocetin downregulates the proinflammatory cytokines in methylcholanthrene-induced rodent tumor model and inhibits COX-2 expression in cervical cancer cells. Biomed Res Int 2015, 829513, 2015.
- Balkwill F: Tumour necrosis factor and cancer. Nat Rev Cancer 9, 361–371, 2009.