Effects of Supernatants from Escherichia coli Nissle 1917 and Faecalibacterium prausnitzii on Intestinal Epithelial Cells and a Rat Model of 5-Fluorouracil-Induced Mucositis

References

• Wang H, Bastian SEP, and Howarth GS: Newly developed synbiotics and the chemotherapy-damaged gut. J Evid Based Complementary Altern Med 18, 198–208, 2013.
   Google Scholar
• Howarth GS, and Wang H: Role of endogenous microbiota, probiotics and their biological products in human health. Nutrients 5, 58–81, 2013.
   PubMed Web of Science ®Google Scholar
• Wang H, Bastian SE, Cheah KY, Lawrence A, and Howarth GS: Escherichia coli Nissle 1917-derived factors reduce cell death and late apoptosis and increase transepithelial electrical resistance in a model of 5-fluorouracil-induced intestinal epithelial cell damage. Cancer Biol Ther 15, 560–569, 2014.
   PubMed Web of Science ®Google Scholar
• Wang H, Bastian SE, Lawrence A, and Howarth GS: Factors derived from Escherichia coli nissle 1917, grown in different growth media, enhance cell death in a model of 5-fluorouracil-induced caco-2 intestinal epithelial cell damage. Nutr Cancer 67, 316–326, 2015.
   PubMed Web of Science ®Google Scholar
• Sokol H, Pigneur B, Watterlot L, Lakhdari O, Bermudez-Humaran LG, et al.: Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci U S A 105, 16731–16736, 2008.
   PubMed Web of Science ®Google Scholar
• Qiu X, Zhang M, Yang X, Hong N, and Yu C: Faecalibacterium prausnitzii upregulates regulatory T cells and anti-inflammatory cytokines in treating TNBS-induced colitis. J Crohns Colitis 7, e558–568, 2013.
   PubMed Web of Science ®Google Scholar
• Varela E, Manichanh C, Gallart M, Torrejon A, Borruel N, et al.: Colonisation by Faecalibacterium prausnitzii and maintenance of clinical remission in patients with ulcerative colitis. Aliment Pharmacol Ther 38, 151–161, 2013.
   PubMed Web of Science ®Google Scholar
• Fujimoto T, Imaeda H, Takahashi K, Kasumi E, Bamba S, et al.: Decreased abundance of Faecalibacterium prausnitzii in the gut microbiota of Crohn's disease. J Gastroenterol Hepatol 28, 613–619, 2013.
   PubMed Web of Science ®Google Scholar
• Louis P, and Flint HJ: Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine. FEMS Microbiol Lett 294, 1–8, 2009.
   PubMed Web of Science ®Google Scholar
• Zhang M, Qiu X, Zhang H, Yang X, Hong N, et al.: Faecalibacterium prausnitzii inhibits interleukin-17 to ameliorate colorectal colitis in rats. PLoS One 9, e109146, 2014.
   PubMed Web of Science ®Google Scholar
• Martin R, Chain F, Miquel S, Lu J, Gratadoux JJ, et al.: The commensal bacterium Faecalibacterium prausnitzii is protective in DNBS-induced chronic moderate and severe colitis models. Inflamm Bowel Dis 20, 417–430, 2014.
   PubMed Web of Science ®Google Scholar
• Prisciandaro LD, Geier MS, Butler RN, Cummins AG, and Howarth GS: Probiotic factors partially improve parameters of 5-fluorouracil-induced intestinal mucositis in rats. Cancer Biol Ther 11, 671–677, 2011.
   PubMed Web of Science ®Google Scholar
• Tomas FM, Knowles SE, Owens PC, Read LC, Chandler CS, et al.: Effects of full-length and truncated insulin-like growth factor-I on nitrogen balance and muscle protein metabolism in nitrogen-restricted rats. J Endocrinol 128, 97–105, 1991.
   PubMed Web of Science ®Google Scholar
• Mashtoub S, Tran CD, and Howarth GS: Emu oil expedites small intestinal repair following 5-fluorouracil-induced mucositis in rats. Exp Biol Med (Maywood) 238, 1305–1317, 2013.
   PubMed Web of Science ®Google Scholar
• Cheah KY, Howarth GS, Yazbeck R, Wright TH, Whitford EJ, et al.: Grape seed extract protects IEC-6 cells from chemotherapy-induced cytotoxicity and improves parameters of small intestinal mucositis in rats with experimentally-induced mucositis. Cancer Biol Ther 8, 382–390, 2009.
   PubMed Web of Science ®Google Scholar
• Tung D, Cheung PH, Tudor G, Booth C, and Saha S: In vivo effects of immunomodulators in a murine model of fluorouracil-induced mucositis. Curr Ther Res Clin Exp 72, 262–272, 2011.
   PubMed Web of Science ®Google Scholar
• Martin R, Miquel S, Chain F, Natividad JM, Jury J, et al.: Faecalibacterium prausnitzii prevents physiological damages in a chronic low-grade inflammation murine model. BMC Microbiol 15, 67, 2015.
   PubMed Web of Science ®Google Scholar
• Tian T, Yu S, and Ma D: Th22 and related cytokines in inflammatory and autoimmune diseases. Expert Opin Ther Targets 17, 113–125, 2013.
   PubMed Web of Science ®Google Scholar
• Carlsson AH, Yakymenko O, Olivier I, Hakansson F, Postma E, et al.: Faecalibacterium prausnitzii supernatant improves intestinal barrier function in mice DSS colitis. Scand J Gastroenterol 48, 1136–1144, 2013.
   PubMed Web of Science ®Google Scholar
• Al-Sadi R, Boivin M, and Ma T: Mechanism of cytokine modulation of epithelial tight junction barrier. Frontiers in bioscience (Landmark edition) 14, 2765–2778, 2009.
   PubMed Web of Science ®Google Scholar
• Capaldo CT, and Nusrat A: Cytokine regulation of tight junctions. Biochim Biophys Acta 1788, 864–871, 2009.
   PubMed Web of Science ®Google Scholar
• Laval L, Martin R, Natividad JN, Chain F, Miquel S, et al.: Lactobacillus rhamnosus CNCM I-3690 and the commensal bacterium Faecalibacterium prausnitzii A2-165 exhibit similar protective effects to induced barrier hyper-permeability in mice. Gut Microbes 6, 1–9, 2015.
   PubMed Web of Science ®Google Scholar
• Ukena SN, Singh A, Dringenberg U, Engelhardt R, Seidler U, et al.: Probiotic Escherichia coli Nissle 1917 inhibits leaky gut by enhancing mucosal integrity. PLoS One 2, e1308, 2007.
   PubMed Web of Science ®Google Scholar
• Zyrek AA, Cichon C, Helms S, Enders C, Sonnenborn U, et al.: Molecular mechanisms underlying the probiotic effects of Escherichia coli Nissle 1917 involve ZO-2 and PKCzeta redistribution resulting in tight junction and epithelial barrier repair. Cell Microbiol 9, 804–816, 2007.
   PubMed Web of Science ®Google Scholar
• Lindsay RJ, Geier MS, Yazbeck R, Butler RN, and Howarth GS: Orally administered emu oil decreases acute inflammation and alters selected small intestinal parameters in a rat model of mucositis. Br J Nutr 104, 513–519, 2010.
   PubMed Web of Science ®Google Scholar
• De Angelis PM, Svendsrud DH, Kravik KL, and Stokke T: Cellular response to 5-fluorouracil (5-FU) in 5-FU-resistant colon cancer cell lines during treatment and recovery. Mol Cancer 5, 20, 2006.
   PubMed Web of Science ®Google Scholar
• Pulli B, Ali M, Forghani R, Schob S, Hsieh KL, et al.: Measuring myeloperoxidase activity in biological samples. PLoS One 8, e67976, 2013.
   PubMed Web of Science ®Google Scholar
• Miquel S, Leclerc M, Martin R, Chain F, Lenoir M, et al.: Identification of metabolic signatures linked to anti-inflammatory effects of Faecalibacterium prausnitzii. mBio 6, e00300–00315, 2015.
   Web of Science ®Google Scholar
• Li M, Wang B, Zhang M, Rantalainen M, Wang S, et al.: Symbiotic gut microbes modulate human metabolic phenotypes. Proc Natl Acad Sci U S A 105, 2117–2122, 2008.
   PubMed Web of Science ®Google Scholar
• Lalles J: Gut wall homeostasis: roles and regulations of barrier funcion, inducible heat shock proteins and intestinal alkaline phosphatase (abstr). Proceedings of the International Scientific Conference on Probiotics and Prebiotics, (abstr) 13, 2014.
   Google Scholar