316
Views
15
CrossRef citations to date
0
Altmetric
Review

Prophylactic and Therapeutic Effects of Curcumin on Treatment-Induced Oral Mucositis in Patients with Head and Neck Cancer: A Meta-Analysis of Randomized Controlled Trials

, &
Pages 740-749 | Received 13 Apr 2020, Accepted 25 May 2020, Published online: 09 Jun 2020

References

  • Kawashita Y, Soutome S, Umeda M, Saito T. Oral management strategies for radiotherapy of head and neck cancer. Japan Dent Sci Rev. 2020;56(1):62–7. doi:10.1016/j.jdsr.2020.02.001
  • Leung HWC, Chan ALF. Glutamine in alleviation of radiation-induced severe oral mucositis: A meta-analysis. Nutr Cancer. 2016;68(5):734–42. doi:10.1080/01635581.2016.1159700
  • Sonis ST. The pathobiology of mucositis. Nat Rev Cancer. 2004;4(4):277–84. doi:10.1038/nrc1318
  • Blakaj A, Bonomi M, Gamez ME, Blakaj DM. Oral mucositis in head and neck cancer: Evidence-based management and review of clinical trial data. Oral Oncol. 2019;95:29–34. doi:10.1016/j.oraloncology.2019.05.013
  • Cho HK, Jeong YM, Lee HS, Lee YJ, Hwang SH. Effects of honey on oral mucositis in patients with head and neck cancer: A meta-analysis. Laryngoscope. 2015;125(9):2085–92. doi:10.1002/lary.25233
  • Kuo CC, Wang RH, Wang HH, Li CH. Meta-analysis of randomized controlled trials of the efficacy of propolis mouthwash in cancer therapy-induced oral mucositis. Support Care Cancer. 2018;26(12):4001–9. doi:10.1007/s00520-018-4344-5
  • Van Sebille YZA, Stansborough R, Wardill HR, Bateman E, Gibson RJ, Keefe DM. Management of mucositis during chemotherapy: From pathophysiology to pragmatic therapeutics. Curr Oncol Rep. 2015;17(11):50. doi:10.1007/s11912-015-0474-9
  • Lalla RV, Bowen J, Barasch A, Elting L, Epstein J, Keefe DM, McGuire DB, Migliorati C, Nicolatou-Galitis O, Peterson DE, et al. MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy. Cancer. 2014;120(10):1453–61. doi:10.1002/cncr.28592
  • Tayyem RF, Heath DD, Al-Delaimy WK, Rock CL. Curcumin content of turmeric and curry powders. Nutr Cancer. 2006;55(2):126–31. doi:10.1207/s15327914nc5502_2
  • Nabavi SM, Russo GL, Tedesco I, Daglia M, Orhan IE, Nabavi SF, Bishayee A, Nagulapalli Venkata KC, Abdollahi M, Hajheydari Z, et al. Curcumin and melanoma: From chemistry to medicine. Nutr Cancer. 2018;70(2):164–75.:doi:10.1080/01635581.2018.1412485
  • Liczbiński P, Michałowicz J, Bukowska B. Molecular mechanism of curcumin action in signaling pathways: Review of the latest research. Phytother Res. 2020. doi:10.1002/ptr.6663
  • Rao S, Dinkar C, Vaishnav LK, Rao P, Rai MP, Fayad R, Baliga MS. The Indian spice turmeric delays and mitigates radiation-induced oral mucositis in patients undergoing treatment for head and neck cancer: An investigational study. Integr Cancer Ther. 2014;13(3):201–10. doi:10.1177/1534735413503549
  • Normando AGC, de Menêses AG, de Toledo IP, Borges GÁ, de Lima CL, Dos Reis PED, Guerra ENS. Effects of turmeric and curcumin on oral mucositis: A systematic review. Phytother Res. 2019;33(5):1318–29. doi:10.1002/ptr.6326
  • Delavarian Z, Pakfetrat A, Ghazi A, Jaafari MR, Homaei Shandiz F, Dalirsani Z, Mohammadpour AH, Rahimi HR. Oral administration of nanomicelle curcumin in the prevention of radiotherapy-induced mucositis in head and neck cancers. Spec Care Dentist. 2019;39(2):166–72. doi:10.1111/scd.12358
  • Arun P, Sagayaraj A, Mohiyuddin SA, Santosh D. Role of turmeric extract in minimising mucositis in patients receiving radiotherapy for head and neck squamous cell cancer: a randomised, placebo-controlled trial. J Laryngol Otol. 2020;134(2):159–6. doi:10.1017/S0022215120000316
  • Higgins JPT, Green S editors. Cochrane handbook for systematic reviews of interventions version 5.1.0 (updated March 2011. The Cochrane Collaboration, 2011. www.cochrane-handbook.org
  • Lachenbruch PA, Cohen J. Statistical power ANALYSIS for the behavioral sciences. Journal of the American Statistical Association 2nd. 1989;84(408):1096–500. doi:10.2307/2290095
  • Higgins JP, Thompson SG, Deeks JJ, Altman DG. Measuring inconsistency in meta-analyses. BMJ. 2003;327(7414):557–60. doi:10.1136/bmj.327.7414.557
  • Mansourian A, Amanlou M, Shirazian S, Moosavian JZ, Amirian A. The effect of “Curcuma Longa” topical gel on radiation-induced oral mucositis in patients with head and neck cancer. 2015.
  • Charantimath S. Use of curcumin in radiochemotherapy induced oral mucositis patients: A control trial study. World Acad Sci Eng Technol Int J Med Health Bio-Medl Bioeng Pharm Eng. 2016;10:147–52.
  • Patil K, Guledgud MV, Kulkarni PK, Keshari D, Tayal S. Use of curcumin mouthrinse in radio-chemotherapy induced oral mucositis patients: a pilot study. J Clin Diagn Res. 2015;9(8):ZC59–ZC62. doi:10.7860/JCDR/2015/13034.6345
  • Oronsky B, Goyal S, Kim MM, Cabrales P, Lybeck M, Caroen S, Oronsky N, Burbano E, Carter C, Oronsky A. A review of clinical radioprotection and chemoprotection for oral mucositis. Transl Oncol. 2018;11(3):771–8. doi:10.1016/j.tranon.2018.03.014
  • Peterson DE, Bensadoun R-J, Roila F, Roila F. Management of oral and gastrointestinal mucositis: ESMO clinical practice guidelines. Ann Oncol. 2011;22 Suppl 6(Suppl 6):vi78–84. doi:10.1093/annonc/mdr391
  • Elad S, Meidan I, Sellam G, Simaan S, Zeevi I. Topical curcumin for the prevention of oral mucositis in pediatric patients: case series. Altern Ther Health Med. 2013;19:21–4.
  • Daly L, Dolan R, Power D, Ní Bhuachalla É, Sim W, Fallon M, Cushen S, Simmons C, McMillan DC, Laird BJ, et al. The relationship between the BMI-adjusted weight loss grading system and quality of life in patients with incurable cancer. J Cachexia Sarcopenia Muscle. 2020;11(1):160–8. doi:10.1002/jcsm.12499
  • Doello K, Ortiz R, Alvarez PJ, Melguizo C, Cabeza L, Prados J. Latest in vitro and in vivo assay, clinical trials and patents in cancer treatment using curcumin: A literature review. Nutr Cancer. 2018;70(4):569–78. doi:10.1080/01635581.2018.1464347
  • Verma V. Relationship and interactions of curcumin with radiation therapy. World J Clin Oncol. 2016;7(3):275–83. doi:10.5306/wjco.v7.i3.275
  • Sonis ST. Mucositis: The impact, biology and therapeutic opportunities of oral mucositis. Oral Oncol. 2009;45(12):1015–20. doi:10.1016/j.oraloncology.2009.08.006
  • Raber-Durlacher JE, Elad S, Barasch A. Barasch A: Oral mucositis. Oral Oncol. 2010;46(6):452–6. doi:10.1016/j.oraloncology.2010.03.012
  • Farhood B, Mortezaee K, Goradel NH, Khanlarkhani N, Salehi E, Nashtaei MS, Najafi M, Sahebkar A. Curcumin as an anti-inflammatory agent: Implications to radiotherapy and chemotherapy. J Cell Physiol. 2019;234(5):5728–40. doi:10.1002/jcp.27442
  • Schmidt TR, Curra M, Wagner VP, Martins MAT, de Oliveira AC, Batista AC, Valadares MC, Marreto RN, Martins MD. Mucoadhesive formulation containing Curcuma longa L. reduces oral mucositis induced by 5-fluorouracil in hamsters. Phytother Res. 2019;33(4):881–90. doi:10.1002/ptr.6279

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.